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Open Journal of Thoracic Surgery 2022年第1期12卷 1-10页

作者： md. Abir Tazim Chowdhury Sohail Ahmed md. Zulfiqur Haider S. m. A. Zulker Nine md. Kamrul Hasan md. Estiak Ullah Sahid musfaqus Shalehin md. Abdullah Al-mahammud Kabir Niaz Ahmed munama magdum Department of Cardiothoracic and Vascular Surgery Evercare Hospital Dhaka Bangladesh Department of Cardiothoracic Anesthesia Evercare Hospital Dhaka Bangladesh Department of Community medicine Shaheed Monsur Ali Medical College Dhaka Bangladesh

Among chronic pulmonary infections, pulmonary actinomycosis is a rare one, caused by a gram-positive microaerophilic bacterium called Actinomyces. Aside from cervicofacial or abdominopelvic actinomycosis, pulmonary involvement is rare, and sometimes this type of infection results in a misdiagnosis of pulmonary tuberculosis or carcinoma. Clinical presentation of pulmonary actinomycosis could be acute or subacute, with lobar involvement. However, the disease is most commonly diagnosed at the chronic phase, with patients presenting mild fever, weight loss, and occasional hemoptysis. Here, we described the case of a 30-year-old male patient, presented with a history of respiratory complaints for more than three years and was diagnosed clinically and radiologically as a case of a destroyed left lung. Later on, post-operative tissue diagnosis was confirmed—pulmonary actinomycosis.

关键词： Pulmonary Actinomycosis Destroyed Lung Diagnostic Dilemma

Laubry-Pezzi Syndrome in an Adult male Patient and Its Surgical Correction: A Case Report and Literature Review

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World Journal of Cardiovascular Surgery 2022年第10期12卷 219-228页

作者： md. Abir Tazim Chowdhury md. Zulfiqur Haider Sohail Ahmed S. m. A. Zulker Nine Arup Khan Naheed Rayhan musfaqus Shalehin md. Sifat Uddin Nakib Shah Alam Saiful Islam Khan Niaz Ahmed munama magdum Department of Cardiothoracic and Vascular Surgery Evercare Hospital Dhaka Bangladesh Department of Cardiothoracic Anesthesia Evercare Hospital Dhaka Bangladesh Department of Community medicine Shaheed Monsur Ali Medical College Dhaka Bangladesh

This Laubry-Pezzi syndrome is rarely seen in patients with ventricular septal defect (VSD) combined with aortic regurgitation. A 20-year-old male patient presented to the Cardiothoracic and vascular surgery department with a large VSD with severe aortic regurgitation (AR). However, he was first symptomatic at 12 years of age and initially treated by medical management with the suggestion of surgical correction. Nevertheless, he was delayed getting surgical management due to his financial problem. This article reported on an adult patient with Laubry-Pezzi syndrome and his surgical correction and outcome. The association of congenital defects VSD and AR needs to be identified and corrected in early life for better outcomes.

关键词： Laubry-Pezzi syndrome Adult Ventricular Septal Defect (VSD) Aortic Regurgitation (AR) Surgical Correction of Adult VSD

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新型自组装纳米胶团人工过氧化物酶研究

广州化工 2014年第16期42卷 34-37页

作者：杨天杨晓璐张钰帅耿方勇康慧茹肖保林洪军穆萨维姆瓦赫迪河南大学生命科学学院河南开封475000 河南大学生物工程研究所河南开封475000 伊朗德黑兰大学生物化学与生物物理研究所

十二烷基肌氨酸钠与天然细胞色素c通过自组装方式构建了一种新型纳米胶团结构人工过氧化物酶(Artificial Peroxidase,AP)。采用紫外可见光分光光度计对AP酶促反应过程进行研究。表明AP在较宽的pH范围具有活性,并在pH 5.0,100 mmol/L磷... 详细信息

十二烷基肌氨酸钠与天然细胞色素c通过自组装方式构建了一种新型纳米胶团结构人工过氧化物酶(Artificial Peroxidase,AP)。采用紫外可见光分光光度计对AP酶促反应过程进行研究。表明AP在较宽的pH范围具有活性,并在pH 5.0,100 mmol/L磷酸盐缓冲液中达到最大。该AP的米氏常数Km、催化速率kcat以及催化效率分别为1.70μmol/L、0.11 s-1、0.065μm-1s-1,催化效率为天然辣根过氧化物酶的90.2%。

关键词：细胞色素c 人工过氧化物酶十二烷基肌氨酸钠纳米胶团催化效率

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大型射电望远镜脉冲星观测能力的模拟研究

新疆大学学报（自然科学版） 2012年第2期29卷 203-210页

作者：阿里木·克力木艾力·伊沙木丁阿布都加怕尔·如苏力迪里努尔·阿布都热西提袁建平新疆大学物理科学与技术学院新疆乌鲁木齐830046 中国科学院新疆天文台新疆乌鲁木齐830011

本文首先采用Lorimer等人提出的脉冲星主要参数模型,根据Parkes多波束巡天与Parkes高银纬巡天发现的1059颗正常脉冲星和27颗毫秒脉冲星的实际情况,使用monte Carlo方法,模拟得到脉冲星在整个银河系中分布的样本;然后,对该模拟样本,通过... 详细信息

本文首先采用Lorimer等人提出的脉冲星主要参数模型,根据Parkes多波束巡天与Parkes高银纬巡天发现的1059颗正常脉冲星和27颗毫秒脉冲星的实际情况,使用monte Carlo方法,模拟得到脉冲星在整个银河系中分布的样本;然后,对该模拟样本,通过设定射电望远镜各观测参数,进行虚拟探测,比较研究了一台虚拟的处于乌鲁木齐地理纬度上的110 m口径射电望远镜与美国Green Bank天文台口径为100 m射电望远镜(GBT)对脉冲星巡天观测方面的能力.特别分析了观测波段、积分时间、消色散终端参数、巡天天区等方面对巡天观测产生的影响,讨论了观测参数的优化选择问题.本研究结果显示,在共同可观测天区,在纬度42°处的110m口径射电望远镜搜寻脉冲星的能力比GBT的高约12%;该望远镜在银纬为|b|mHz～1500 mHz之内的观测频率搜寻脉冲星效率最高;消色散终端的子通道带宽对正常脉冲星的搜寻选择1.0 mHz,对毫秒脉冲星的搜寻选择0.1 mHz为最佳;同时考虑增加极端消零脉冲星样本的需要以及巡天周期的限制,每波束积分时间可选择3600 s.

关键词：脉冲星射电望远镜 monte Carlo模拟

Unusual Presentation of a Large multi-Septated Cystic Hygroma: A Case Report and Comprehensive Literature Review

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Surgical Science 2023年第7期14卷 486-495页

作者： md. Abir Tazim Chowdhury Sohail Ahmed md. Zulfiqur Haider Niaz Ahmed A. K. m. Fazlul Haque Nasrin Aktar Arup Khan md. Abdullah-Al-mahammud Kabir md. Sifat Uddin Abrar Bin Ahsan Trishna Sarker md. Khaled Hossain munama magdum Department of Cardiothoracic and Vascular Surgery Evercare Hospital Dhaka Dhaka Bangladesh Department of Cardiothoracic Anesthesia Evercare Hospital Dhaka Dhaka Bangladesh Department of Plastic and Reconstructive Surgery Evercare Hospital Dhaka Dhaka Bangladesh Department of Community medicine Shahid Monsur Ali Medical College Dhaka Bangladesh

Background: Cystic hygromas are primarily found in the cervicofacial, thoracic, and abdominal regions, with limited occurrences in other areas. Despite existing literature on this condition, comprehensive descriptions and mRI findings of cystic hygromas in the extremities are rare. Aim: This case report aims to present a unique instance of a cystic hygroma in the left thigh. The objective is to provide detailed insights into the characteristics of this atypical presentation. Case Presentation: The case involves a 2-year-10 month-old girl with a cystic hygroma in her left thigh. The report includes a comprehensive description of the lesion’s clinical features and diagnostic evaluation, emphasizing the mRI findings to enhance understanding of this rare occurrence. Conclusion: This case report highlights the rarity of cystic hygromas outside the cervicofacial, thoracic, and abdominal regions, explicitly focusing on the occurrence in the left thigh. By presenting detailed insights into the clinical features, mRI findings, histopathological findings, and the surgical approach employed, this report contributes to the existing knowledge on this condition in atypical locations and informs future treatment strategies.

关键词： Cystic Hygroma Lymphangioma multi-Septated Cystic Hygroma Unusual Presentation Vascular Tumors Benign Soft Tissue Tumors

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巴音布鲁克高寒区气象观测资料分析

沙漠与绿洲气象 2017年第4期11卷 48-53页

作者：吴烨巩庆黄向春买买提艾力.买买提依明产秀媚张广兴李红军刘新春何清中国气象局乌鲁木齐沙漠气象研究所新疆乌鲁木齐830002 库尔勒市气象局新疆库尔勒841000 巴音布鲁克气象站新疆和静841310 布尔津县气象局新疆布尔津836600

利用2011—2013年巴音布鲁克高寒无人区的自动气象站资料,揭示了观测区域的气象条件,给出部分气象参数的变化特征。结果表明:(1)迎风坡盛行风向为东南风(SE)和北风(N),其中SE占35%,N占25%,N向风力集中4级以下,SE明显偏大,3级风比重15%,... 详细信息

利用2011—2013年巴音布鲁克高寒无人区的自动气象站资料,揭示了观测区域的气象条件,给出部分气象参数的变化特征。结果表明:(1)迎风坡盛行风向为东南风(SE)和北风(N),其中SE占35%,N占25%,N向风力集中4级以下,SE明显偏大,3级风比重15%,4级风比重7%,5级风比重4%;6级风比重1%。背风坡主导风向角度范围在247.5°~337.5°,风力基本在6级以下,3~5级风出现频率最高,6级及以上风力出现频率不足1%。(2)日平均气温≤-10℃日数所占观测总日数的百分比,其值分别为:0.0%(恰西)、44.5%(江布肯达坂)、9.8%(江巴口子)、15.1%(铁力买提达坂)。恰西、江布肯达坂、江巴口子、铁力买提达坂4站日平均相对湿度≥80%的频率分别为5.9%、18.4%、16.1%和22.6%。(3)换算得出恰西、江布肯达坂、江巴口子、铁力买提达坂观测期间10 m高度最大瞬时风速与小时平均风速分别为33.8/27.9、41.0/27.3、25.7/17.7、34.0/17.2 m/s。

关键词：巴音布鲁克中天山高海拔气象要素

Effects of methyl palmitate and lutein on LPS-induced acute lung injury in rats

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World Journal of Respirology 2013年第2期3卷 20-28页

作者： El-Sayed m Ammar maha H Sharawy Asem A Shalaby Dina S El-Agamy Department of Pharmacology and Toxicology Faculty of PharmacyMansoura University Mansoura 35516 Egypt Department of Pathology Faculty of Medicine Mansoura University Mansoura 35516 Egypt

AIm: To investigate the effects of methyl palmitate and lutein on lipopolysaccharide(LPS)-induced acute lung injury(ali) in rats and explore the possible mechanisms. mETHODS: male Sprague-Dawley rats were divided into 4 groups:(1) control;(2) LPS;(3) methyl palmitate; and(4) Lutein groups. methyl palmitate(300 mg/kg, ip) was administered 3 times per week on alternating days while lutein(100 mg/kg, oral) was given once daily. After 1 wk of vehicle/methyl palmitate/lutein treatment, ali was induced by a single dose of LPS(7.5 mg/kg, iv). After 24 h of LPS injection, animals were sacrificed then biochemical parameters and histopathology were assessed. RESULTS: Treatment with methyl palmitate attenuated ali, as it significantly decreased the lung wet/dry weight(W/D) ratio, the accumulation of the inflammatory cells in the bronchoalveolar lavage fluid(BALF) andhistopathological damage. However, methyl palmitate failed to decrease lactate dehydrogenase(LDH) activity in BALF. On the other hand, lutein treatment produced significant anti-inflammatory effects as revealed by significant decrease in accumulation of inflammatory cells in lung, LDH level in BALF and histopathological damage. methyl palmitate and lutein significantly increased superoxide dismutase(SOD) and reduced glutathione(GSH) activities with significant decrease in the lung malondialdehyde(mDA) content. Importantly, methyl palmitate and lutein decreased the level of the inflammatory cytokine tumor necrosis factor-α(TNF-α) in the lung. Lutein also reduced LPS-mediated overproduction of pulmonary nitrite/nitrate(NO-2/NO-3), which was not affected by methyl palmitate pretreatment. CONCLUSION: These results demonstrate the potent protective effects of both methyl palmitate and lutein against LPS-induced ali in rats. These effects can be attributed to potent antioxidant activities of these agents, which suppress inflammatory cell infiltration and regulated cytokine effects.

关键词： Acute lung injury Lipopolysaccharide methyl palmitate Lutein Rats

用ELISA方法检测原头节及Egm免疫犬IgG变化情况

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地方病通报 2007年第4期22卷 1-4页

作者：郭宝平张壮志张文宝石宝新古努尔.吐尔逊吐尔洪.依米提哈斯也提艾力王进成新疆农业大学动物医学学院乌鲁木齐830052 新疆畜牧科学院兽医所乌鲁木齐830000

目的用不同的抗原检测免疫犬后的血清,判定所引起的IgG变化和有无与其他虫种的交叉反应。方法在用原头节可溶性粗抗原和Egm家族重组表达蛋白对犬的免疫保护实验中,以原头节可溶性粗抗原、细粒棘球绦虫成虫可溶性粗抗原和多头绦虫可溶性... 详细信息

目的用不同的抗原检测免疫犬后的血清,判定所引起的IgG变化和有无与其他虫种的交叉反应。方法在用原头节可溶性粗抗原和Egm家族重组表达蛋白对犬的免疫保护实验中,以原头节可溶性粗抗原、细粒棘球绦虫成虫可溶性粗抗原和多头绦虫可溶性粗抗原包被检测时,通过间接ELISA的方法检测其中的特异性抗体IgG的变化规律及与多头绦虫抗原有无交叉反应。结果原头节可溶性粗抗原检测出相对应免疫组实验犬IgG应答变化情况,同时用细粒棘球绦虫成虫包被抗原亦检测出IgG存在一定差异,但不十分明显,与多头绦虫无交叉反应。检测Egm重组蛋白免疫组IgG时它们存在一定差异,但不十分明显。结论原头节可溶性粗抗原免疫组通过ELISA的方法较为准确地检测出其IgG的应答情况;Egm重组蛋白免疫组的抗体检测仍需进一步完善。

关键词：原头节可溶性粗抗原细粒棘球绦虫多头绦虫 ELISA IgG

土大黄根提取物对银屑病模型小鼠血清代谢组学指标的影响

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中国药业 2023年第5期32卷 40-46页

作者：巴合沙拉·马乃甫尤力都孜·买买提玉素甫江·艾力阿布都帕塔尔·阿布迪热扎克热比姑丽·伊斯拉木新疆维吾尔自治区维吾尔医药研究所新疆乌鲁木齐830000 新疆维吾尔医方剂学实验室新疆乌鲁木齐830000

目的探讨土大黄根提取物对银屑病模型小鼠血清代谢组学指标的影响。方法将70只Km小鼠随机分为模型对照组(CON组,0.5%羧甲基纤维素钠),化学药阳性对照组(DXm组,1.05 mg/kg醋酸地塞米松片),中药制剂阳性对照组(XYKL组,1.577 g/kg消银颗粒)... 详细信息

目的探讨土大黄根提取物对银屑病模型小鼠血清代谢组学指标的影响。方法将70只Km小鼠随机分为模型对照组(CON组,0.5%羧甲基纤维素钠),化学药阳性对照组(DXm组,1.05 mg/kg醋酸地塞米松片),中药制剂阳性对照组(XYKL组,1.577 g/kg消银颗粒),维吾尔医药阳性对照组(mB组,2 g/kg异常黏液质成熟剂浸膏粉),土大黄根提取物低、中、高剂量组(RE-L组、RE-m组、RE-H组,1,2,4 g/kg),各10只。各组小鼠灌胃相应药物或0.5%羧甲基纤维素钠,每天1次,连续15 d。末次给药后取小鼠血清,苏木精-伊红染色,光学显微镜下观察小鼠尾部皮肤组织的病理形态;采用^(1)H-NmR技术结合正交偏最小二乘法判别分析各组小鼠血清差异性代谢物组分。结果与CON组比较,RE-L组、RE-m组、RE-H组小鼠均出现不同程度的颗粒细胞层增厚或促进颗粒细胞层形成,血清丙氨酸、甘氨酸、肌酸、乳酸、胆碱水平均显著升高,低密度脂蛋白(LDL)、极低密度脂蛋白(VLDL)水平均显著降低(Pm组、RE-H组小鼠血清α-葡萄糖、β-葡萄糖水平均显著升高,糖蛋白水平显著降低(P<0.05);RE-H组小鼠血清苯丙氨酸、不饱和脂类水平均显著升高,丙酮水平显著降低(P<0.05)。结论土大黄根提取物对银屑病模型小鼠有一定治疗作用,可能与其能升高小鼠血清丙氨酸、甘氨酸、乳酸、胆碱的水平及降低LDL与VLDL的水平有关。

关键词：土大黄银屑病血清代谢组学组织病理学作用机制

皱纹盘鲍4个群体与九孔鲍16S rRN A基因遗传差异分析

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水产科学 2014年第11期33卷 702-707页

作者：陈丽申欣向治楚秦银银林权享孟学平江苏省海洋资源开发研究院江苏连云港 222005 江办省海洋生物产业技术协同创新中心江苏连去港 222005 淮海工学院海洋学院江苏连云港222005

采用PCR方法扩增了皱纹盘鲍（4个群体）和九孔鲍（1个群体）共5个群体（53个样本）16S rRNA基因片段（16S），测序获得了1000 bp核苷酸序列，其中669 bp核苷酸序列用于遗传差异分析，旨在评估我国皱纹盘鲍不同群体间及其与九孔鲍间的遗... 详细信息

采用PCR方法扩增了皱纹盘鲍（4个群体）和九孔鲍（1个群体）共5个群体（53个样本）16S rRNA基因片段（16S），测序获得了1000 bp核苷酸序列，其中669 bp核苷酸序列用于遗传差异分析，旨在评估我国皱纹盘鲍不同群体间及其与九孔鲍间的遗传差异。从52个序列中共检测到17种单倍型，其中皱纹盘鲍4个群体有13种单倍型，九孔鲍1个群体（9个样本）有4种单倍型。单倍型核苷酸序列比对显示，变异位点占比对位点的20．5％，基于单倍型的皱纹盘鲍4个群体间的遗传距离为0．002～0．011，平均为0．005；九孔鲍群体内的平均遗传距离为0．004，两种鲍间的平均遗传距离为0．218；两种鲍间的遗传分化系数 F‐统计量 FST平均为0．982，皱纹盘鲍4群体间的 FST值为0．0051～0．0065。本研究显示2种鲍群体内16S变异很小。系统发育分析鲍属11种鲍的聚类关系，显示皱纹盘鲍与盘鲍、日本鲍交叉聚为一支，九孔鲍与杂色鲍也交叉聚为一支，4个种类未聚成单系支。

关键词：皱纹盘鲍九孔鲍 16S rRNA基因遗传差异