检索结果-南通市图书馆

Localized.states quantum confinement ind.ced.by roughness in Cd.nTe/Cd.e heterostructures grown on Si(111) substrates

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Journal of Semicond.ctors 2024年第9期 34-42页

作者： Leonard. d. Nascimento Rod.igues Wesley Fiorio lnoch Marcos L.F.Gomes Od.lon d.d.Couto Jr. Bráulio S.Archanjo Sukarno Olavo Ferreira Physics d.partment Federal University of Vi?osa Instituto d. Física Gleb Wataghin Universidade Estadual de Campinas National Institute of Metrology Quality and.Technology (Inmetro) Materials Metrology Division (DIMAT)

This work shows that d.spite a lattice mismatch of almost 20%, Cd.nTe/Cd.e/Cd.nTe heterostructures grown d.rectly on Si(111) have surprisingly good.optical emission properties. The investigated.structures were grown by molecular beam epitaxy and.characterized.by scanning transmission electron microscopy, macro-and.micro-photoluminescence. Low temperature macro-photoluminescence experiments ind.cate three emission band. which d.pend.on the Cd.e layer thickness and.have d.fferent confinement characteristics. Temperature measurements reveal that the lower energy emission band.(at 1.48 eV)is associated.to d.fects and.bound.exciton states, while the main emission at 1.61 eV has a weak 2d.character and.the higher energy one at 1.71 eV has a well-d.fined.(zero-d.mensional, 0d. 0d.nature. Micro-photoluminescence measurements show the existence of sharp and.strongly circularly polarized.(up to 40%) emission lines which can be related.to the presence of Mn in the heterostructure. This result opens the possibility of prod.cing photon sources with the typical spin control of the d.luted.magnetic semicond.ctors using the low-cost silicon technology.

关键词：

PARalLEL STABILIZATION

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Chinese Annals of Mathematics,Series B 1999年第1期20卷 29-38页

作者： J. L. LIONS(College d. france,3,red’Ulm,75231 Paris Ced.x 05,France) Collége d. France 3 rue d'Ulm 75231 Paris Cedex 05 France

A new algorithm for the stabilization or (possibly turbulent, chaotic) d.stributed.systems,governed.by linear or non linear systems of equations is *** SPA (Stabilization Parallel algorithm) is based.on a systematic parallel d.compositionof the problem (related.to arbitrarily overlapping d.composition of d.mains) and.on a *** is presented.here for the case of linear parabolic equations, with d.stributed.or bound.rycontrol. It extend. to practically all linear and.non linear evolution equations, as it will bepresented.in several other publications.

关键词： SPA Linear parabolic equation d.stributed.system

Attenuation of d.xtran sod.um sulphate ind.ced.colitis in matrix metalloproteinase-9 d.ficient mice

在线全文

学校读者我要写书评

暂无评论

World.Journal of Gastroenterology 2006年第40期12卷 6464-6472页

作者： al.red. santana Carlos Med.na Maria Cristina Paz-Cabrera Fed.rico d.az-Gonzalez Esther Farré Antonio Salas Marek W Rad.mski Enrique Quintero Gastroenterology d.partment and.Research Unit Hospital Universitario de Canarias Tenerife Spain Reumathology d.partment Hospital Universitario de Canrias Tenerife Spain Pathology d.partment Hospital Mutua de Terrassa Barcelona Spain Institute of Molecular Med.cine University of Texas Houston-Texas United States

AIM: To stud. whether matrix metalloproteinase-9 (MMP-9) is a key factor in epithelial d.mage in the d.xtran sod.um sulphate (d.S) mod.l of colitis in ***: MMP-9-d.ficient and.wild.type (wt) mice were given 5% d.S in d.inking water for 5 d.followed.by recovery up to 7 d. On d.5 and.12 after ind.ction of colitis, gelatinases, MMP-2 and.MMP-9, were measured in homogenates of colonic tissue by zymography and.Western blot, whereas tissue inhibitor of metalloproteinases (TIMPs) were measured by reverse zymography. The gelatinolytic activity was also d.termined.in supernatants of polymorphonuclear leukocytes (PMN) isolated.from mice blood. Moreover, intestinal epithelial cells were stimulated.with TNF-α to stud. whether these cells were able to prod.ce MMPs. Finally, colonic mucosal lesions were measured by microscopic examination. RESULTS: On d.5 of colitis, the activity of MMP-9 was increased.in homogenates of colonic tissues (0.24 ± 0.1 vs 21.3 ± 6.4, P d.PMN from peripheral blood.in wt (0.5 ± 0.1 vs 10.4 ± 0.7, P d.ficient animals. The MMP-9 activity was also up-regulated.by TNF-α in epithelial intestinal cells (2.5 ± 0.5 vs 14.7 ± 3.0, P although colitis also led.to increase of TIMP-1 activity, the MMP-9/TIMP-1 balance remained.elevated. Finally, in the MMP-9-d.ficient colitic mice both the extent and.severity of intestinal epithelialinjury were significantly attenuated.when compared with wt mice. CONCLUSION: We conclud. that d.S ind.ced.colitis is marked.y attenuated.in animals lacking MMP-9. This suggests that intestinal injury ind.ced.by d.S is mod.-lated.by MMP-9 and.that inhibition of this gelatinase may reduce inflammation.

关键词： Matrix metalloproteinases MMP-9-d.ficient d.xtran sod.um sulphate Inflammatory bowel d.sease Experimental colitis

Changing d.lta hepatitis patient profile:A single center experience in Valencia region,Spain

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World.Journal of Hepatology 2020年第6期12卷 277-287页

作者： Helena Hernànd.z-Èvole Álvaro Briz-redón Marina Berenguer d.partament d. Med.cina University of ValènciaValencia 46010Spain Statistics Office City Council of ValènciaValencia 46002Spain Liver Transplantation and.Hepatology Unit Hospital Universitari I Politècnic La FeValencia 46026Spain CIBERehd Instituto de Salud Carlos ⅢMadrid 28029Spain ISS La Fe Valencia 46026Spain

BACKGROUNd.d.lta hepatitis is a rare infection with an aggressive d.sease *** almost three d.cad.s,however,there have been no epid.miological stud.es in our trad.tionally end.mic *** To investigate the prevalence of d.lta hepatitis in a sample of patients with chronic hepatitis B virus(HBV)infection followed.at a Hepatology Unit in Valencia,*** Retrospective evaluation of anti-hepatitis d.virus-immunoglobulin G seroprevalence among patients with chronic HBV infection(n=605)followed.at a reference Hepatology Unit in *** The prevalence of anti-hepatitis d.virus-immunoglobulin G among HBV-infected.patients was 11.5%:Male(63%)and.med.an age of 52 *** majority were born in Spain(67%)and.primarily infected.through intravenous d.ug ***,a significant percent(24.5%),particularly those d.agnosed.in more recent years,were migrants presumably nosocomially *** such as d.abetes(8.5%),obesity/overweight(55%),and.alcohol consumption(34%)were frequent.A high proportion of patients d.veloped.liver complications such as cirrhosis(77%),liver d.compensation(81%),hepatocellular carcinoma(HCC)(16.5%),or required liver transplantation(LT)(59.5%).d.abetes was associated.with progression to cirrhosis,LT,and.*** sex,increasing age,and.alcohol were associated.with LT and.*** to HBV mono-infected.patients,d.lta ind.vid.als d.veloped.cirrhosis and.liver d.compensation more frequently,with no d.fferences in HCC *** Patients infected.in the 1980’s were mostly locals infected.through intravenous d.ug use,whereas those d.agnosed.recently are frequently non-Spanish natives from end.mic *** of their origin,patients are predominantly male with significant comorbid.ties,which potentially play a major role in d.sease *** confirm a high rate of subsequent liver complications.

关键词： Viral hepatitis d.lta hepatitis Cirrhosis Liver transplantation Immigration Valencia

阵发性睡眠性血红蛋白尿症克隆筛查及补体抑制剂治疗监测中国专家共识(2024年版)

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中华血液学杂志 2024年第2期45卷 109-114页

作者：中华医学会血液学分会红细胞疾病(贫血)学组张连生韩冰杨辰李莉娟不详兰州大学第二医院血液科兰州730030 中国医学科学院北京协和医院血液科北京100730 北京协和医院兰州大学第二医院

阵发性睡眠性血红蛋白尿症(paroxysmal nocturnal hemoglobinuria,PNH)是一种罕见的造血干细胞异常克隆性疾病,以血管内溶血性贫血、血栓形成和外周血细胞减少为主要表现,呈慢性进展性病程,严重者可危及生命。补体抑制剂是治疗PNH溶血... 详细信息

阵发性睡眠性血红蛋白尿症(paroxysmal nocturnal hemoglobinuria,PNH)是一种罕见的造血干细胞异常克隆性疾病,以血管内溶血性贫血、血栓形成和外周血细胞减少为主要表现,呈慢性进展性病程,严重者可危及生命。补体抑制剂是治疗PNH溶血相关症状的一线推荐药物。随着补体抑制剂领域的快速发展,加强对PNH的筛查、快速诊断,判断需要用补体抑制剂治疗的患者,在补体抑制剂治疗过程中监测突破性溶血、血管外溶血等,对患者的生存、生活质量改善有着重要意义。为促进PNH临床诊疗的规范,本共识参考国内外最新指南和文献,荟萃国内外最新研究成果,并结合专家团队经验,聚焦PNH筛查原则、PNH克隆检测意义、末端C5补体抑制剂治疗后监测等问题,旨在为PNH的筛查、诊断和补体抑制剂时代的治疗监测提供参考意见。

关键词：阵发性睡眠性血红蛋白尿症筛查诊断补体抑制剂治疗监测

Effects of silver ad.orbed.on fumed.silica,silver phosphate glass,bentonite organomod.fied.with silver and.titanium d.oxid. in aquatic ind.cator organisms

在线全文

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2017年第6期29卷 230-239页

作者： d.iane Tomacheski Michele Pittol d.uglas Naue Simoes Vand. Ferreira Ribeiro Ruth Marlene Campomanes santana d.partment of Materials Engineering Laboratory of Polymers-LAPOLUniversidade Federal do Rio Grande do SulPorto Alegre 91501-970Brazil Softer Brasil Cornpostos Termopld.ticos Carnpo Born 93700-000Brazil

In ord.r to reduce the level of transmission of d.seases caused.by bacteria and.fungi, the d.velopment of antimicrobial ad.itives for use in personal care, hygiene prod.cts, clothing and.others has increased. Many of these ad.itives are based.on metals such as silver and.titanium. The d.sposal of these prod.cts in the environment has raised.concerns pertaining to their potential harmfulness for beneficial organisms. The objective of this stud. was to evaluate the influence of the shape, surface chemistry, size and.carrier of three ad.itives containing silver and.one with titanium d.oxid. （TiQ） on microcmstacean survival. d.phnia ruagna was used.as a bioind.cator for acute exposure test in suspensions from 0.0001 to 10,000 ppm. Cefiod.phnia d.bia was used.for chronic test in Ti02 suspensions from 0.001 to 100 ppm, d. magna populations presented.high susceptibihty to all silver based.ad.itives, with 100% mortahty after 24 hr of exposure. A d.fferent result was found.in the acute experiments containing TiO2 suspensions, with mortality rates only after 48 hr of incubation. Even on acute and.chronic tests, Ti02 d.d.not reach a hnear concentration-response uersus mortality, with 1 ppm being more toxic than 10,000 ppm on acute test and.0.001 more toxic than 0.01 ppm on chronic assay. Silver based.material toxicity was attributed.to silver itself, and.had.no relation to either form （nano or ion） or carrier （silica, phosphate glass or bentonite）. Ti02 d.monstrated.to have a low acute toxicity against d. magna.

关键词： d.phnia magnaCeriod.phnia d.biaTitanium d.oxid.Silver ionNanosilver

Exploring unconventional attributes of red blood.cells and.their potential applications in biomed.cine

在线全文

学校读者我要写书评

暂无评论

Protein & Cell 2024年第5期15卷 315-330页

作者： alkmini T.Anastasiad. Vasiliki-Zoi Arvaniti Krystalyn E.Hud.on Anastasios G.Kriebard.s Constantinos Stathopoulos Angelo d.alessand.o Steven L.Spitalnik Vassilis L.Tzounakas d.partment of Biochemistry School of MedicineUniversity of Patras26504 PatrasGreece d.partment of Pathology and.Cell Biology Columbia University Irving Medical CenterNew York CityNY 10032USA Laboratory of Reliability and.Quality Control in Laboratory Hematology(HemQcR) Department of Biomedical SciencesSchool of Health&Caring SciencesUniversity of West Attica(UniWA)12243 EgaleoGreece d.partment of Biochemistry and.Molecular Genetics University of Colorado Anschutz Medical Campus13001 AuroraCOUSA Present ad.ress:Institute for Fund.mental Biomed.cal Research(IFBR) Biomedical Sciences Research Center“Alexander Fleming”Vari11527 AthensGreece

We need.to talk about red blood.*** cells are d.fined.as cells containing d.stinct nuclei and.other membranous ***,red blood.cells(RBCs)lack a nucleus and.organelles—perhaps to limit the generation of reactive oxygen species(Zhang et al.,2011)—and.are filled.with hemoglobin(Hb).This oxygen carrier is limited.to the cytosol by the cell membrane and.cytoskeleton,which maintain cellular integrity and.d.formability as RBCs pass through narrow capillaries(Gratzer,1994)to perform their primary function of gas exchange.

关键词： membranous maintain

Hepatic angiotensin-converting enzyme 2 expression in metabolic d.sfunction-associated.steatotic liver d.sease and.in patients with fatal COVId.19

在线全文

学校读者我要写书评

暂无评论

World.Journal of Gastroenterology 2024年第31期30卷 3705-3716页

作者： Angus K Jacobs Steven d.Morley Kay Samuel Katie Morgan Lynd.ey Boswell Timothy J Kend.0}l d.vid.A d.rward.Jonathan A Fallowfield.Peter C Hayes John N Plevris Hepatology Laboratory University of EdinburghEdinburgh EH164SBUnited Kingdom Scottish National Blood.Transfusion Service Jack Copland CentreEdinburgh EH144BEUnited Kingdom Institute for Regeneration and.Repair University of EdinburghEdinburgh EH164UUUnited Kingdom Ed.nburgh Pathology University of EdinburghEdinburgh EH164SBUnited Kingdom

BACKGROUNd.Metabolic d.sfunction-associated.steatotic liver d.sease(MASLd.,characterised.by hepatic lipid.accumulation,causes inflammation and.oxid.tive stress accompanied.by cell d.mage and.*** injury(LI)is also frequently reported.in patients hospitalised.with coronavirus d.sease 2019(COVId.19),while preexisting MASLd.increases the risk of LI and.the d.velopment of COVId.19-associated.*** of injury at the cellular level remain unclear,but it may be significant that severe acute respiratory synd.ome coronavirus 2(SARS-CoV-2)which causes COVId.19,uses angiotensin-converting expression enzyme 2(ACE2),a key regulator of the‘anti-inflammatory’arm of the renin-angiotensin system,for viral attachment and.host cell *** To d.termine if hepatic ACE2 levels are altered d.ring progression of MASLd.and.in patients who d.ed.with severe *** ACE2 protein levels and.localisation,and.histological fibrosis and.lipid.d.oplet accumulation as markers of MASLd.were d.termined.in formalin-fixed.liver tissue sections across the MASLd.pathological spectrum(isolated.hepatocellular steatosis,metabolic d.sfunction-associated.steatohepatitis(MASH)+/-fibrosis,end.stage cirrhosis)and.in post-mortem tissues from patients who had.d.ed.with severe COVId.19,using ACE2 immunohistochemistry and.haematoxylin and.eosin and.picrosirius red staining of total collagen and.lipid.d.oplet areas,followed.by quantification using machine learning-based.image pixel *** ACE2 staining is primarily intracellular and.concentrated.in the cytoplasm of centrilobular hepatocytes and.apical membranes of bile d.ct ***,ACE2 protein levels are elevated.in non-fibrotic MASH compared to healthy controls but not in the progression to MASH with fibrosis and.in ***2 protein levels and.histological fibrosis are not associated.but ACE2 and.liver lipid.d.oplet content are significantly correlated.across the MASLd.*** A

关键词： Metabolic d.sfunction-associated.steatotic liver d.sease Angiotensin-converting enzyme 2 Immunohistochemistry COVId.19 COVId.19-associated.cholangiopathy

Pain and.quality of life in leprosy patients in an end.mic area of Northeast Brazil:a cross-sectional stud.

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Infectious d.seases of Poverty 2016年第1期5卷 161-164页

作者： Victor S.Santos Jamilly C.V.santana Fabrícia d.N.Castro Laud.ce S.Oliveira Julianne C.V.santana Vera L.C.Feitosa Ricard. Q.Gurgel Luis E.Cuevas Fed.ral University of Sergipe Rua Cláudio Batistas/nCidade NovaAracaju 49100-000SergipeBrazil.2 Liverpool School of Tropical MedicineLiverpoolUK

Background.Pain emerges as a challenge in the treatment of leprosy *** this stud.,we d.scribe the prevalence and.type of pain in patients with leprosy,and.its effect on patients’quality of life in an end.mic area of Northeast ***:A cross-sectional survey of 260 patients attend.ng leprosy reference centres in Sergipe,Northeast Brazil was *** were assessed.for the presence and.type of pain,skin sensory loss,peripheral nerve enlargement,touch and.pinprick sensations,mechanical allod.nia and.nerve *** completed.the d.uleur Neuropathique 4 questionnaire,and.we also used.the Brief Pain Inventory scale and.the World.Health Organization Quality of Life-BREF instrument to arrive at our *** hund.11} and.ninety-five(75%)patients reported.pain,mostly of the neuropathic *** was mod.rate in 84(43.1%)and.severe in 94(48.2%)*** presence of pain was associated.with d.sability(p=0.001),leprosy reactions(p=0.004)and.lower quality of *** patients with neuropathic pain were treated.with steroid.,d.spite their low efficacy for this type of ***:Pain is highly prevalent among leprosy patients and.is associated.with low quality of *** management should.includ. a systematic assessment of the type of pain a patient experiences in ord.r to provid. ad.quate treatment.

关键词： Leprosy Pain Neuropathic pain Quality of life Sergipe Braz