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Potential role of micro ribonucleic acids in screening for anal cancer in human papilloma virus and human immunodeficiency virus related malignancies

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World Journal of Gastrointestinal Pathophysiology 2021年第4期12卷 59-83页

作者： Samar al Bitar Tala Ballouz Samer Doughan Hala Gali-Muhtasib Nesrine Rizk Department of Biology American University of BeirutBeirut 11072020Lebanon Department of Internal Medicine American University of Beirut Medical CenterBeirut 11072020Lebanon Department of Surgery American University of Beirut Medical CenterBeirut 11072020Lebanon Department of Biology and Center for Drug Discovery American University of BeirutBeirut 11072020Lebanon

Despite advances in antiretroviral treatment(ART),human immunodeficiency virus(HIV)continues to be a major global public health issue owing to the increased mortality rates related to the prevalent oncogenic viruses among people living with HIV(PLWH).Human papillomavirus(HPV)is the most common sexually transmitted viral disease in both men and women ***-risk or oncogenic HPV types are associated with the development of HPV-related malignancies,including cervical,penile,and anal cancer,in addition to oral *** incidence of anal squamous cell cancers is increasing among PLWH,necessitating the need for reliable screening methods in this population at *** fact,the currently used screening methods,including the Pap smear,are invasive and are neither sensitive nor *** are interested in circulatory and tissue micro ribonucleic acids(miRNAs),as these small non-coding RNAs are ideal biomarkers for early detection and prognosis of *** miRNAs are deregulated during HIV and HPV infection and their deregulation contributes to the pathogenesis of ***,we will review the molecular basis of HIV and HPV co-infections and focus on the pathogenesis and epidemiology of anal cancer in *** limitations of screening for anal cancer and the need for a reliable screening program that involves specific miRNAs with diagnostic and therapeutic values is also discussed.

关键词： Human papillomavirus Human immunodeficiency virus Anal cancer Micro ribonucleic acids Biomarkers Cancer screening

Coping Strategies among Parents of Children with Acute Lymphoblastic Leukemia

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Health 2017年第7期9卷 987-999页

作者： Rosnah Sutan Nahlah Abduljaleel al-Saidi Zarina Abdul Latiff Hishamshah Mohd Ibrahim Department of Community Health Universiti Kebangsaan Malaysia Kuala Lumpur Malaysia Department of Pediatrics Universiti Kebangsaan Malaysia Kuala Lumpur Malaysia Institute of Pediatrics General Hospital Kuala Lumpur Kuala Lumpur Malaysia

Background: Having a child with acute lymphoblastic leukemia represents challenges to the family which may impact their quality of life. In such circumstances, parents use various coping strategies to face this stressful situation, and understanding the relation of coping strategies on quality of life among parents of children with acute lymphoblastic leukemia may provide professionals with ideas about how to support them which in turn may improve their quality of life. Aim: The aim of the present study was to assess the correlation between coping strategies and the health related quality of life of parents whose children are suffering from acute lymphoblastic leukemia. Study design: A cross-sectional design using guided self-administered questionnaire by a single researcher was used. Methods: A universal sample consisted of 299 parents of children with acute lymphoblastic leukemia (alL) was recruited from Hospital Universiti Kebangsaan Malaysia and Kuala Lumpur Institute Pediatrics. The response rate was 98%. The data collection tools were WHOQOL BREF which is the World Health Organization Quality of Life shorter version and Brief COPE questionnaires. Results: The results revealed that half of the parents perceived their health related quality of life as good. The highest scores for parents were reported on the social relationship domain meanwhile the lowest were reported on the environmental health domain. In regard to the coping strategies, it was found that religion was most frequently used while humor was the least to be used. Moreover, there was a significant positive relationship between quality of life of the parents and problem-focused coping style and a significant negative relationship with emotion-focused coping style. Conclusion: On the basis of the finding of present study, an appropriate intervention could be design to include program that promote the use of problem-focused copings such as active coping and planning and discourage the use of emotion-f

关键词： Health Related QOL Childhood Cancer Leukemia Coping

Application of Scale Relativity (ScR) Theory to the Problem of a Particle in a Finite One-Dimensional Square Well (FODSW) Potential

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Journal of Quantum Information Science 2011年第1期1卷 7-17页

作者： Saeed N. T al-Rashid Mohammed A. Z Habeeb Khalid A Ahmad Physics Department College of Science Al-Anbar University Anbar Iraq

In the present work, and along the lines of Hermann, ScR theory is applied to a finite one-dimensional square well potential problem. The aim is to show that scale relativity theory can reproduce quantum mechanical results without employing the Schr?dinger equation. Some mathematical difficulties that arise when obtaining the solution to this problem were overcome by utilizing a novel mathematical connection between ScR theory and the well-known Riccati equation. Computer programs were written using the standard MATLAB 7 code to numerically simulate the behavior of the quantum particle in the above potential utilizing the solutions of the fractal equations of motion obtained from ScR theory. Several attempts were made to fix some of the parameters in the numerical simulations to obtain the best possible results in a practical computer CPU time within limited local computer facilities [1,2]. Comparison of the present results with the corresponding results obtained from conventional quantum mechanics by solving the Schr?dinger equation, shows very good agreement. This agreement was improved further by optimizing the parameters used in the numerical simulations [1,3]. This represents a new example where scale relativity theory, based on a fractal space-time concept, can accurately reproduce quantum mechanical results without invoking the Schr?dinger equation.

关键词： Square Well ScR Theory Numerical Simulations Fractal Space-Time

Eczema Disease Detection and Recognition in Cloud Computing

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Computer Technology and Application 2016年第1期7卷 57-64页

作者： Azmi Shawkat Abdulbaki Samir Abdulrasoul Khadim Saif al-din M. Najim College of Computer Science & Info. Tech. University of Anbar Ramadi Iraq Dept. of Computer Science University of Al-Maarif College Ramadi Iraq

ED (eczema disease) is the most common form of skin inflammation in humans. Most of the skin disease is curable at initial stages with the advancement of technology. So, an early detection of skin disease can save the patient’s life and prevent theprogression of the disease. It is proposed to have a study on the diagnosis of ED using BpNN (backpropagation neural network) in cloud computing approach due to that BpNN is currently widespread research area in medicine and plays an important role in a decision support system. In this paper, an attempt has been made to make use of BpNN in the medical field along cloud computing to detect ED.

关键词： BpNN cloud computing EDD (eczema disease detection) Skin Inflammation GA (genetic algorithm)

手征性媒体中双各向同性散射特征的研究(英文)

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河南科学 2008年第5期26卷 534-539页

作者： al-Majdi Kadhum 祁明 al-Moussawy Raed 华南理工大学自动化科学与工程学院广州510640 库发大学电力工程学院伊拉克库发999049

讨论麦克斯韦等式下广义圆极化在手征性媒体中的不同的本构关系.在某类手征性媒体中广义圆极化波的场,与在非手征性媒体中麦克斯韦等式描述的同构关联有着相同的形式;但是不同的圆极化对应场的物理参数也不同.不管传播方向如何,这样的... 详细信息

讨论麦克斯韦等式下广义圆极化在手征性媒体中的不同的本构关系.在某类手征性媒体中广义圆极化波的场,与在非手征性媒体中麦克斯韦等式描述的同构关联有着相同的形式;但是不同的圆极化对应场的物理参数也不同.不管传播方向如何,这样的圆极化波(左或右)传播同等的波数.本文基于球面积分等式研究广义双各向同性物体的电磁散射特征.应用基层顶面等效性原理,能够把在均匀的双各向同性域中的电磁场用分布在它的边界面上的等量电磁流表示出来.

关键词：本构关系圆极化左手圆极化等效性原理力矩分配法

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基于激光诱导击穿光谱的铝合金定量分析

基于激光诱导击穿光谱的铝合金定量分析

作者： Ahlam Abdul salam Abdul Jabbar al-Muaalemi 西安电子科技大学

学位级别：硕士

激光诱导击穿光谱法（LIBS）是一种基于光辐射光谱学的分析方法,该方法使用激光脉冲来蒸发、气化并激发热等离子体作为光谱的辐射源。尽管LIBS已经在许多领域展现其实用性和吸引力,但LIBS的定量分析能力被认为是其致命的缺点。从原理的... 详细信息

激光诱导击穿光谱法（LIBS）是一种基于光辐射光谱学的分析方法,该方法使用激光脉冲来蒸发、气化并激发热等离子体作为光谱的辐射源。尽管LIBS已经在许多领域展现其实用性和吸引力,但LIBS的定量分析能力被认为是其致命的缺点。从原理的角度来看,这可能是由于激光诱导等离子体作为LIBS应用的光谱发射源的复杂性质。在LIBS技术里,激光诱导等离子体的时间和空间特性被认为是关键点之一。另一方面,从分析的角度来看,激光的直接烧蚀是LIBS的主要特征。然而,对于某些材料,例如粉末,液体,这种烧蚀可能是相当有限的。适当的样品制备或处理允许在金属表面沉积一层均匀的薄膜从而可以极大提高这类材料的分析性能。本文在LIBS分析方面做了三个工作。第一个工作是通过使用校准曲线（CC）和偏最小二乘（PLS）两种方法对不同距离和不同延迟时间的标准铝合金样品进行定量分析。铝合金样品中主要元素和痕量元素定量分析的数值结果表明,就回归系数而言,（PLS）方法优于（CC）方法。此外,在激光诱导击穿光谱中使用（PLS）方法是同时定量分析铝合金元素的理想选择。第二个工作是使用三种方法对液体中的铬元素（Cr）进行了定量分析,这三种方法分别是校正曲线（CC）方法,偏最小二乘（PLS）方法和神经网络方法。实验的数值结果表明三种方法在回归系数方面均表现良好,线性拟合的回归系数值均大于0.97。此外,我们观察到,与其他方法相比,（PLS）方法在回归系数方面显示出最好的结果。第三个工作是激光诱导击穿光谱（LIBS）结合人工神经网络（ANN）对三种植物样品（女贞,珊瑚树,竹子）的叶子进行了分类。讨论了正确分类率（CCR）与人工神经网络设置的关系。在多层感知器网络中,测试集数据的ANN模型的CCR达到了 99.99

关键词：激光诱导击穿技术定量分析偏最小二乘法(PLS) 神经网络

Analysis of Association between Interleukin-6 (IL6), Interleukin-13 (IL13) and Tumor Necrosis Factor-alpha (TNF-alpha) Gene Polymorphisms and Genetic Susceptibility of Rheumatoid Arthritis in Kuwaiti Arab

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Open Journal of Rheumatology and Autoimmune Diseases 2022年第4期12卷 99-113页

作者： Adel M. al-Awadhi Mohammad Z. Haider Aminah M. al-Awadi Anita K. Kalarikkal Jalaja Sukumaran Eman A. H. Hasan Youssef Bartella Department of Medicine College of Medicine Kuwait University Jabriya Kuwait Rheumatic Disease Unit Amiri Hospital Dasman Kuwait Department of Pediatrics College of Medicine Kuwait University Jabriya Kuwait

Background: Rheumatoid arthritis (RA) is a common autoimmune disease in which a combination of risk alleles from different susceptibility genes predisposes the patients to develop clinical symptoms following exposure to environmental factors. RA is a chronic and progressive disease characterized by synovial inflammation that results in destruction in the affected joints and severe problems in individual’s mobility. Several immune-related risk factors have been associated with RA, these include single nucleotide polymorphisms (SNPs) in cytokine genes. The impact of these cytokine gene polymorphisms is due to their association either with elevated serum levels and/or variations in their serum levels are associated with disease-onset and progression. The objective of this study was to investigate the role of Interleukin-6 (IL6), Interleukin-13 (IL13) and Tumor necrosis factor-alpha (TNF-alpha) gene polymorphisms in genetic susceptibility of RA in Kuwaiti patients. Methods: We have determined the genotypes of IL6 gene (-174G/C;rs1800795), IL13 gene (R130Q;rs20541) and TNF-alpha gene (-308A/G' rs1800629) polymorphisms in 192 Kuwaiti patients with RA and compared it to that in 104 healthy controls. The diagnosis of RA was based on the American College of Rheumatology (ACR) classification criteria. The genotypes for IL6, IL13 and TNF-alpha gene polymorphisms were determined by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) methods and confirmed by DNA sequencing. Results: The frequency of IL6 gene (-174G/C;rs1800795) and TNF-alpha gene (-308A/G' rs1800629) polymorphisms manifested a statistically significant difference between Kuwaiti RA patients and controls (P = 0.02 and 0.002 respectively). In contrast, the frequency of IL13 gene (R130Q;rs20541) polymorphism did not show a significant difference between Kuwaiti RA patients and controls. Conclusions: Our data showed an association of two cytokine gene polymorphisms (i.e. IL6 gene -174G/C;rs

关键词： Genotype Cytokine Gene Polymorphism Rheumatoid Arthritis Kuwait

Triple-Band Metamaterial Inspired Antenna for Future Terahertz(THz)Applications

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Computers, Materials & Continua 2022年第7期72卷 1071-1087页

作者： Adel Y.I.Ashyap S.alamri S.H.Dahlan Z.Z.Abidin M.Inam Abbasi Huda A.Majid M.R.Kamarudin Y.A.al-Gumaei M.Hashim Dahri Center for Applied Electromagnetic(EMCenter) Faculty of Electrical and Electronic EngineeringUniversiti Tun Hussein Onn Malaysia(UTHM)Batu Pahat86400JohorMalaysia Faculty of Engineering Electrical Engineering Dep. Al Baha UniversityAlaqiq65799Al-BahaSaudi Arabia Advanced Telecommunication Research Center(ATRC) Faculty of Electrical and Electronic EngineeringUniversiti Tun Hussein Onn Malaysia(UTHM)Batu Pahat86400JohorMalaysia Faculty of Electrical and Electronic Engineering Technology Universiti Teknikal Malaysia MelakaHang Tua Jaya76100Durian TunggalMelakaMalaysia Department of Mathematics Physicsand Electrical EngineeringNorthumbria UniversityNE18ST Newcastle Upon TyneUK Department of Electronic Engineering Dawood University of Engineering and TechnologyKarachi74800Pakistan

For future healthcare in the terahertz(THz)band,a triple-band microstrip planar antenna integrated with metamaterial(MTM)based on a polyimide substrate is *** frequencies of operation are 500,600,and 880 *** triple-band capability is accomplished by etching metamaterial on the patch without affecting the overall antenna *** of a partial ground plane,a full ground plane is used as a buffer to shield the body from back radiation emitted by the *** overall dimension of the proposed antenna is 484×484μm^(2).The antenna’s performance is investigated based on different crucial factors,and excellent results are *** gain for the frequencies 500,600,880GHz is 6.41,6.77,10.1 dB,respectively while the efficiency for the same frequencies is 90%,95%,96%,*** research has been conducted by mounting the presented antenna on a single phantom layer with varying dielectric *** results show that the design works equally well with and without the phantom model,in contrast to a partially ground antenna,whose performance is influenced by the presence of the phantom *** a result,the presented antenna could be helpful for future healthcare applications in the THz band.

关键词： THz metamaterial triple-band wireless body area networks(WBAN)

A Novel Decoding Method for Non-Binary TCM Codes

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Communications and Network 2014年第1期6卷 22-28页

作者： Riyadh A. al-Hilali Abdulkareem S. Abdallah Raad H. Thaher College of Engineering al-Mustansiriyah University Baghdad Iraq College of Engineering Al-Mustansiriyah University Baghdad Iraq College of Engineering Basrah University Basrah Iraq

A new non-binary decoding method, which is called Yaletharatalhussein decoding algorithm, is designed and implemented for decoding non-binary convolutional codes which is based on the trellis diagram representing the convolutional encoder. Yaletharatalhussein decoding algorithm outperforms the Viterbi algorithm and other algorithms in its simplicity, very small computational complexity, decoding reliability for high states TCM codes that suitable for Fourth-Generation (4G), decreasing errors with increasing word length, and easy to implement with real-time applications. The proposed Yaletharatalhussein decoding algorithm deals with non-binary error control coding of the convolutional and TCM codes. Convolutional codes differ from block codes in that a block code takes a fixed message length and encodes it, whereas a convolutional code can encode a continuous stream of data, and a hard-decision decoding can easily be realized using the Yaletharatalhussein algorithm. The idea of non-binary codes has been extended for symbols defined over rings of integers, which outperform binary codes with only a small increase in decoding complexity. The simulation results show that the performance of the nonbinary TCM-based Yaletharatalhussein algorithm outperforms the binary and non-binary decoding methods.

关键词： Convolutional Codes Coded Modulation (CM) Trellis Code Modulation (TCM) Non-Binary Error Correcting Codes Groups Rings of Integers