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Transition Behavior in the Use of Complementary and Alternative Medicine during Follow-up after Radical Prostatectomy: A Multicenter Survey in Japan

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Health 2010年第12期2卷 1460-1465页

作者： Koji Yoshimura Yoshiteru Sumiyoshi Toshiyuki Kamoto Osamu Ogawa Yoichi Arai Yoshiyuki Kakehi akito terai Hiroshi Kanamaru Mutsushi Kawakita Naoko Kinukawa 不详

We evaluated the prevalence of use of complementary and alternative medicine (CAM), as well as the transitional nature of its use, before and after radical prostatectomy in Japa-nese patients with localized prostate cancer. Methods: We enrolled 376 patients, who an-swered a self-administered questionnaire on CAM use, psychological health locus of control (HLC), and general-health-related quality of life (GHQL). Detailed information regarding CAM use according to the transtheoretical model, and the time at initiation and abandonment of CAM use were assessed. Medical information was also extracted from patient charts. Results: 45.7% of patients belonged to the “precontem-plation” stage, 29.8% to the “contemplation” stage, 1.9% to the “preparation” stage, 14.4% to the “action” stage, and 8.2% to the “relapse” stage. Although patient age and educational status had a significant impact on stage of CAM use, HLC and GHQL were not associated with them. The time-course of prevalence of CAM use during follow-up was divided into three phases: “initial,” “rapid-increase,” and “main-tenance”. Conclusions: Among patients under-going radical prostatectomy, non-users can be classified into several behavioral stages, while users do not use CAM constantly during fol-low-up.

关键词： Prostate Cancer Alternative Medicine Health Survey Health Locus Of Control Epidemiology

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Esophageal diverticulum: New perspectives in the era of minimally invasive endoscopic treatment

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World Journal of Gastroenterology 2019年第12期25卷 1457-1464页

作者： Hiroki Sato Manabu Takeuchi Satoru Hashimoto Ken-ichi Mizuno Koichi Furukawa akito Sato Junji Yokoyama Shuji terai Division of Gastroenterology Niigata University Medical and Dental Hospital Division of Gastroenterology Nagaoka Red Cross Hospital Division of Gastroenterology Niigata City General Hospital Division of Gastroenterology Nagaoka Chuo General Hospital

Esophageal diverticula are rare conditions that cause esophageal symptoms, such as dysphagia, regurgitation, and chest pain. They are classified according to their location and characteristic pathophysiology into three types: epiphrenic diverticulum, Zenker's diverticulum, and Rokitansky diverticulum. The former two disorders take the form of protrusions, and symptomatic cases require interventional treatment. However, the esophageal anatomy presents distinct challenges to surgical resection of the diverticulum, particularly when it is located closer to the oral orifice. Since the condition itself is not malignant,minimally invasive endoscopic approaches have been developed with a focus on alleviation of symptoms. Several types of endoscopic devices and techniques are currently employed, including peroral endoscopic myotomy(POEM). However,the use of minimally invasive endoscopic approaches, like POEM, has allowed the development of new disorder called iatrogenic esophageal diverticula. In this paper, we review the pathophysiology of each type of diverticulum and the current state-of-the-art treatment based on our experience.

关键词： Diverticulum Esophagus Epiphrenic diverticulum Zenker's diverticulum Rokitansky diverticulum Iatrogenic disease Esophageal achalasia Peroral endoscopic myotomy Diverticulectomy

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Colorectal neuroendocrine carcinoma: A case report and review of the literature

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World Journal of Clinical Cases 2019年第14期7卷 1865-1875页

作者： Tomoaki Yoshida Kenya Kamimura Kazunori Hosaka Koji Doumori Hiromitsu Oka akito Sato Yasuo Fukuhara Shoji Watanabe Tomomi Sato Akira Yoshikawa Takashi Tomidokoro Shuji terai Division of Gastroenterology and Hepatology Graduate School of Medical and Dental SciencesNiigata UniversityNiigata 951-8510Japan Division of Gastroenterology and Hepatology Nagaoka Chuo General HospitalNiigata 940-0861Japan

BACKGROUND Colorectal neuroendocrine carcinoma (NEC) is a rare tumor that demonstrates aggressive growth pattern with ingrowth into the tract, metastasis to the other organs, and invasion to the surrounding organs;these clinical characteristics result in poor prognosis. Surgical resection appears as an effective approach;however, because it is difficult to accurately diagnose NEC during the early stage and owing to its aggressive growth pattern, development of a reliable standard chemotherapy regimen and management strategies are essential. CASE SUMMARY Here, we report the case of patient with NEC showing an aggressive growth pattern that resulted in the rupture of the tumor to the outside the colon after stenting of the internal colonic stenosis. In addition, the tumor invaded into the duodenum, thereby causing duodenal stenosis that required an additional stent in the duodenum. This aggressive growth pattern is one of the main features of the NEC that is different from adenocarcinoma. To clarify the clinical characteristics, we reviewed 60 recently reported cases, including data on tumor location, size, treatment, and prognosis. CONCLUSION We consider that the information presented here is of great significance for the diagnosis, treatment, and management of symptoms of the patients with NEC.

关键词： Neuroendocrine carcinoma Colon Colorectal mixed adenoneuroendocrine carcinoma Growth Case report

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