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Quantum advantages for image filtering on images with efficient encoding and lower-bounded signal-to-noise ratio

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Science China(Physics,Mechanics & Astronomy) 2024年第9期67卷 2-12页

作者： Zidong Cui Shan Jin akira Sone Xiaoting Wang Institute of Fundamental and Frontier Sciences University of Electronic Science and Technology of ChinaChengdu 610051China Key Laboratory of Quantum Physics and Photonic Quantum Information Ministry of EducationUniversity of Electronic Science and Technology of ChinaChengdu 611731China Department of Physics University of MassachusettsBoston 02125USA

Quantum image processing has long been a fascinating field,but establishing the existence of quantum speedup for all images remains *** this study,we aim to identify a subset of images for which a quantum algorithm can be developed with a guaranteed ***,we present a quantum image filtering algorithm that exhibits an exponential speedup for efficiently encoded images with a lower-bounded signal-to-noise *** approach relies on a fixed-point Grover's search to emulate the effect of Hadamard multiplication with the filtering *** demonstrate its effectiveness,we apply our method to three typical filtering ***,we emphasize the significance of the efficient-encoding assumption by illustrating that the quantum speedup may diminish for images lacking efficient *** work underscores the importance of exploring image types and features to realize potential quantum advantages in image processing.

关键词： quantum computing quantum image filtering quantum speedup

Tomographic particle image velocimetry measurement on three-dimensional swirling flow in dual-stage counter-rotating swirler

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Chinese Journal of Aeronautics 2024年第3期37卷 7-20页

作者： Yuyang ZHOU Ling DONG Mingtao SHANG Jibao LI akira RINOSHIKA Key Laboratory of Fluid Mechanics of Ministry of Education Beihang UniversityBeijing 100191China School of Mechanical and Automotive Engineering Shanghai University of Engineering ScienceShanghai 201620China AECC Commercial Aircraft Engine Co. Ltd.Shanghai 200241China Department of Mechanical Systems Engineering Yamagata UniversityYamagata 992-8510Japan

Three-Dimensional(3D)swirling flow structures,generated by a counter-rotating dualstage swirler in a confined chamber with a confinement ratio of 1.53,were experimentally investigated at Re=2.3×10^(5)using Tomographic Particle Image Velocimetry(Tomo-PIV)and planar Particle Image Velocimetry(PIV).Based on the analysis of the 3D time-averaged swirling flow structures and 3D Proper Orthogonal Decomposition(POD)of the Tomo-PIV data,typical coherent flow structures,including the Corner Recirculation Zone(CRZ),Central Recirculation Zone(CTRZ),and Lip Recirculation Zone(LRZ),were *** counter-rotating dual-stage swirler with a Venturi flare generates the independence process of vortex breakdown from the main stage and pilot stage,leading to the formation of an LRZ and a smaller CTRZ near the nozzle *** confinement squeezes the CRZ to the corner and causes a reverse rotation flow to limit the shape of the CTRZ.A large-scale flow structure caused by the main stage features an explosive breakup,flapping,and Precessing Vortex Core(PVC).The explosive breakup mode dominates the swirling flow structures owing to the expansion and construction of the main jet,whereas the flapping mode is related to the wake *** limits the expansion of PVC and causes it to contract after the impacting area.

关键词： Coherent structures Dual-stage counter-rotating swirler cup Precessing vortex core Proper orthogonal decomposition Swirling flow Tomographic particle image velocimetry

Medaka factor in the germline alpha(figα)is indispensable for oogenesis but not for gonadal sex differentiation

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Aquaculture and Fisheries 2024年第3期9卷 347-354页

作者： Katsuyasu Kamimura Masato Kinoshita akira Kanamori Division of Biological Science Graduate School of ScienceNagoya UniversityNagoyaAichi464-8602Japan Division of Applied Biosciences Graduate School of AgricultureKyoto UniversityKyoto606-8502Japan

A basic helix-loop-helix transcription factor,figα,is one of the earliest marker genes of oocyte differentiation in *** the present study,we made figαknockout medaka by CRISPR/Cas9,expecting aborted progress of oogenesis,to see if differentiation of somatic ovarian tissues is ***αknockout male gonads differentiated normally into testes with functional *** females,on the other hand,were sterile;there are oocytes only up to *** growing oocytes in diplotene were *** phenotype was already apparent at 10 days after hatching,when diplotene oocytes start to develop in the ***,several putative target genes of figαwere not expressed in the mutant female *** studies showed that medaka lacking germ cells have morphologically abnormal gonads and female to male sex reversal ***αknockout female gonads differentiated morphologically into ovaries,suggesting that in medaka,figαknockout prevents oogenesis progress into diplotene stage,and ovarian differentiation do not need developed oocytes beyond pachytene *** ovarian phenotype reminded us of"pachytene checkpoint",which blocks meiotic progress into diplotene when chromosomal abnormalities are ***,we further analyzed phenotype of oocytes in the mutant *** number of oocytes at each meiotic stage suggested that oogenesis normally proceeded up to pachytene *** number of apoptotic oocytes in the knockout ovaries was ***,we did not detect any abnormal pairings or unrepaired double-strand breaks by *** together,figαknockout likely stop oocyte growth at or around pachytene via unknown mechanisms other than"pachytene checkpoint"and arrested oocytes remained in the *** is in contrast to figαknockout mice where all oocytes underwent apoptosis quickly after birth.

关键词： bHLH transcription factor CRISPR/Cas9 Pachytene checkpoint Oocyte growth Medaka

Recent trends in bone metastasis treatments:A historical comparison using the new Katagiri score system

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World Journal of Clinical Cases 2024年第15期12卷 2499-2505页

作者： Kenji Matsuda Kazuhiro Shimazu Hanae shinozaki Koji Fukuda Taichi Yoshida Daiki Taguchi Kyoko Nomura Hiroyuki Shibata Department of Clinical Oncology Akita University Graduate School of MedicineAkita 010-8543Japan Department of Environmental Health Science and Public Health Akita University Graduate School of MedicineAkita 010-8543Japan Department of Comprehensive Cancer Control Akita University Graduate School of MedicineAkita 010-8543Japan

BACKGROUND Bone metastasis has various negative *** of daily living(ADL)and quality of life(QOL)can be significantly decreased,survival may be impacted,and medical expenses may *** is estimated that at least 5%cancer patients might be suffering from bone *** 2016,we published the Comprehensive Guidelines for the Diagnosis and Treatment of Bone *** then,the therapeutic outcomes for patients have gradually *** life expectancy is a major determinant of surgical intervention,the strategy should be modified if the prolongation of survival is to be *** To monitor how bone metastasis treatment has changed before and after launch of our guidelines for bone *** For advanced cancer patients with bone metastasis who visited the Department of Clinical Oncology at Akita University hospital between 2012 and 2023,parameters including the site and number of bone metastases,laboratory data,and survival time,were extracted from electronic medical records and the Katagiri score was *** association with survival was determined for each *** Data from 136 patients were *** 1-year survival rate for the poor prognosis group with a higher Katagiri score was 20.0%in this study,which was 6%and an apparent improvement from 2014 when the scoring system was *** factors significantly affecting survival included five or more bone metastases than less(P=0.0080),and treatment with chemotherapy(P<0.001),bone modifying agents(P=0.0175)and immune checkpoint inhibitors(P=0.0128).In recent years,advances in various treatment methods have extended the survival period for patients with advanced *** is necessary not only to simply extend survival time,but also to maintain ADL and improve *** Various therapeutic interventions including surgical approach for bone metastasis,which is a disorder of locomotor organs,are increasingly *** and scoring system for p

关键词： Bone metastasis New Katagiri scoring system Prognosis Immune check point inhibitors Survival

Moving doubly heavy baryon in a strongly coupled plasma via holography

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Chinese Physics C 2024年第8期48卷 42-55页

作者： Xuan Liu Jia-Jie Jiang Xun Chen Mitsutoshi Fujita akira Watanabe School of Nuclear Science and Technology University of South ChinaHengyang 421001China School of Mathematics and Physics University of South ChinaHengyang 421001China

Gauge/gravity duality is used to study the properties of the doubly heavy baryon(QQq)at finite rapidity and temperature in heavy-ion *** investigate the impact of rapidity on string breaking and screening of QQq and compare these effects with the results for QQ¯in *** reveal that the string-breaking distances of QQq and QQ¯are close in the confined state,and the effects of rapidity and temperature on the string breaking are not *** interesting result shows that QQq cannot be determined at sufficiently high temperatures and ***,QQ¯can exist under any conditions as long as the separation distance is sufficiently ***,the screening distances of QQq and QQ¯are compared at finite rapidity and *** on the above analysis,we infer that QQ¯is more stable than QQq at finite rapidity and temperature.

关键词： holographic QCD QGP heavy quark

Pan-cancer analysis of RNA 5-methylcytosine reader (ALYREF)

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Oncology Research 2024年第3期32卷 503-515页

作者： XING YE ZHOUTING TUO KAI CHEN RUICHENG WU JIE WANG QINGXIN YU LUXIA YE akira MIYAMOTO KOO HAN YOO CHI ZHANG WURAN WEI DENGXIONG LI DECHAO FENG Samuel Oschin Comprehensive Cancer Institute Department of MedicineDepartment of Biomedical SciencesCedars-Sinai Medical CenterLos AngelesCA90048USA Department of Urology The Second Afiliated Hospital of Anhui Medical UniversityHefei230601China Department of Urology Institute of UrologyWest China HospitalSichuan UniversityChengdu610041China Department of Pathology Ningbo Diagnostic Pathology Center Ningbo315021China Department of Public Research Platfom Taizhou Hospital of Zhejiang Province Afliated to Wenzhou Medical UniversityLinhai317000China Department of Rehabilitation West Kyushu UniversityKanzaki shi842-8585Japan Department of Urology Kyung Hee UniversitySeoul446701South Korea Department of Rehabilitation The Afliated Hospital of Southwest Medical UniversityLuwzhou646000China

The incre asing interest in RNA modifications has signifcantly advanced epigenomic and epitranscriptomic *** study focuses on the immuno oncological impact of ALYREF in human cancer through a pan-cancer analysis,enhancing understanding of this gene's role in *** observed differential ALYREF expression between tumor and normal samples,correl ating strongly with prognosis in various cancers,particularly kidney renal papillary cell carcinoma(KIRP)and liver hepatocellular carcinoma(LIHC).ALYREF showed a negative correlation with most tumor-infitrating cells in lung squamous cell carcinoma(LUSC)and lymphoid neoplasm difuse large B-cell lymphoma(DLBC),while positive correlations were noted in IIHC,kidney chromophobe(KICH),mesothelioma(MESO),KIRP,pheochromocytoma and paraganglioma(PARD),and glioma(GBMLGG).Aditionally,ALYREF expression was closely associated with tumor heterogeneity,stemness indices,and a high mutation rate in TP53 across these *** conclusion,ALYREF may serve as an oncogenic biomarker in numerous cancers,meriting further research attention.

关键词： Pan-cancer RNA 5-methylcytosine ALYREF Immwno-oncological efects

The neutrophil–osteogenic cell axis promotes bone destruction in periodontitis

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International Journal of Oral Science 2024年第1期16卷 154-162页

作者： Yutaro Ando Masayuki Tsukasaki Nam Cong-Nhat Huynh Shizao Zang Minglu Yan Ryunosuke Muro Kazutaka Nakamura Masatsugu Komagamine Noriko Komatsu Kazuo Okamoto Kenta Nakano Tadashi Okamura akira Yamaguchi Kazuyuki Ishihara Hiroshi Takayanagi Department of Immunology Graduate School of Medicine and Faculty of MedicineThe University of Tokyo7-3-1HongoBunkyo-kuTokyoJapan Department of Microbiology Tokyo Dental College2-1-14 Kanda-Misaki-choChiyoda-kuTokyoJapan Oral Health Science Center Tokyo Dental College2-9-18Kanda-Misaki-choChiyodakuTokyoJapan Department of Osteoimmunology Graduate School of Medicine and Faculty of MedicineThe University of Tokyo7-3-1HongoBunkyo-kuTokyoJapan Unit of Prosthodontics Laboratory of Oral-Maxillofacial Biology Faculty of Odonto-StomatologyUniversity of Medicine and Pharmacy at Ho Chi Minh CityHo Chi Minh CityVietnam Department of Oral and Maxillofacial Surgery Department of Sensory and Motor System MedicineGraduate School of MedicineThe University of TokyoTokyoJapan Division of Rheumatology Department of Internal MedicineKeio University School of MedicineTokyoJapan Department of Laboratory Animal Medicine Research InstituteNational Center for Global Health and MedicineTokyoJapan

The immune-stromal cell interactions play a key role in health and diseases. In periodontitis, the most prevalent infectious disease in humans, immune cells accumulate in the oral mucosa and promote bone destruction by inducing receptor activator of nuclear factor-κB ligand (RANKL) expression in osteogenic cells such as osteoblasts and periodontal ligament cells. However, the detailed mechanism underlying immune–bone cell interactions in periodontitis is not fully understood. Here, we performed single-cell RNAsequencing analysis on mouse periodontal lesions and showed that neutrophil–osteogenic cell crosstalk is involved in periodontitis-induced bone loss. The periodontal lesions displayed marked infiltration of neutrophils, and in silico analyses suggested that the neutrophils interacted with osteogenic cells through cytokine production. Among the cytokines expressed in the periodontal neutrophils, oncostatin M (OSM) potently induced RANKL expression in the primary osteoblasts, and deletion of the OSM receptor in osteogenic cells significantly ameliorated periodontitis-induced bone loss. Epigenomic data analyses identified the OSM-regulated RANKL enhancer region in osteogenic cells, and mice lacking this enhancer showed decreased periodontal bone loss while maintaining physiological bone metabolism. These findings shed light on the role of neutrophils in bone regulation during bacterial infection, highlighting the novel mechanism underlying osteoimmune crosstalk.

关键词： period neutrophil destruction

赴日清人书法与江户时代日本对中国书法的接受

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故宫博物院院刊 2024年第6期 111-123,151页

作者：松浦章许浩日本关西大学郑州大学外国语与国际关系学院

江户时代日本推崇儒学,涌现出一批喜好汉文化的文人。在书法领域,相对于“和样”书法,日本人对具有中国书法特征的“唐样”书风更加青睐。由于江户日本实行闭关锁国政策,每年定期赴日的仅有前往长崎贸易的清代商船船主、乘员等,其中不... 详细信息

江户时代日本推崇儒学,涌现出一批喜好汉文化的文人。在书法领域,相对于“和样”书法,日本人对具有中国书法特征的“唐样”书风更加青睐。由于江户日本实行闭关锁国政策,每年定期赴日的仅有前往长崎贸易的清代商船船主、乘员等,其中不乏精通书法者。部分日本文人为了得到善书者墨迹,专门造访长崎,请教书法知识。这些书法最能展示当时中国书法的真实面貌,称得上是学习“唐样”书风的首选。

关键词：江户时代 “唐样”书风唐船船主接受中日书法交流

Regulatory role of DREB transcription factors in plant drought, salt and cold tolerance

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Chinese Science Bulletin 2000年第11期45卷 970-975页

作者： K.Yamaguch-shinozaki K.shinozaki Japan International Research Center for Agricultural Sciences Tsukuba 305JapanLaboratory of Plant Molecular BiologyInstitute of Physical and Chemical Research305Japan

rd29A gene of Arabidopsis encodes a LEA-like hydrophilic protein, its expression is induced by drought, high-salt and cold stress. In the promoter region of rd29A gene, there are 2 ORE cis-acting elements involved in responses to these environmental stresses. 5 cDNAs (DREB1A-C and DREB2A-B) encoding DREB transcription factors, which specifically bind to ORE element and control the expression of reporter gene under drought, high-salt and stress, have been isolated by One-Hybrid screening method and with ORE element of rd29A promoter. DREB transcription factors and ORE element function in signal transduction of drought, high-salt and cold stress. One DREB transcription factor can control the expression of several target functional genes involved in plant tolerance to drought, high-salt and cold stress. Thus, it may be an effective strategy to achieve ideal, multiple and fundamental effect for improving plant stress-resistance by DREB gene transfer.

关键词： promoter cis-acting element transcription factor signal transduction gene expression.