An 80-year-old man was under annual surveillance esophagogastroduodenoscopy after endoscopic submucosal dissection(ESD) for early gastric cancer(EGC).Two years after the initial ESD, a 0-Ⅱc type metachronous EGC lesi...
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An 80-year-old man was under annual surveillance esophagogastroduodenoscopy after endoscopic submucosal dissection(ESD) for early gastric cancer(EGC).Two years after the initial ESD, a 0-Ⅱc type metachronous EGC lesion, 8 mm in size, without an ulcer scar, was found in the gastric antrum.The estimated tumor depth was up to the mucosa, and biopsy revealed well and poorly differentiated adenocarcinoma.ESD was performed for this lesion and en bloc resection with negative margins was achieved.Histopathological examination revealed an adenosquamous carcinoma 8 mm in size invading the deep submucosal layer(1600 μm), with lymphovascular invasion, consistent with the diagnosis of non-curative resection.Additional gastrectomy was recommended for this patient; however, two months after the ESD, preoperative computed tomography revealed multiple liver metastases, and the patient was considered as an unsuitable candidate for surgical resection.Systemic chemotherapy was therefore started; however, the patient died of gastric cancer 27 mo after the second ESD.Early gastric adenosquamous carcinoma localized to the mucosa and submucosa is extremely rare and its clinical behavior is not well known.The present report is very significant in that it underscores the distinct possibility of gastric adenosquamous carcinoma being very aggressive and fatal even when detected at an early cancer.
Skin manifestations can be major sources of stress for patients with skin diseases;hence, the effective use of makeup and cosmetic products for these patients has been established. The objective of this study was to d...
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Skin manifestations can be major sources of stress for patients with skin diseases;hence, the effective use of makeup and cosmetic products for these patients has been established. The objective of this study was to determine if makeup can divert observers’ gaze from areas of inflammatory acne lesions. Both base and point makeup were applied to two Japanese female patients with mild to moderate acne vulgaris to hide skin manifestations, as well as to accentuate the eyes and lips. Photographs of their faces were shown, at various stages of makeup application, to 22 observers (11 men and 11 women). The effects of makeup application, and other eye-diverting strategies (e.g., clothing, accessories, and hairstyle), used to draw observers’ gaze away from acne lesions, were evaluated by analyzing observers’ eye movements. As base makeup application proceeded, time to first fixation, total fixation duration, and fixation count changed. Compared to “no makeup”, the time to first fixation, total fixation duration, and fixation count also decreased significantly after point makeup application. The additional eye-diverting strategies used also had significant gaze-diverting effects. Therefore, makeup can be useful for patients with acne to divert others’ gaze from lesions. Therefore, it should be actively integrated into acne management.
Tire waste is discharged at 3 or 4 million wheels per year in Japan. Tire waste is mainly treated as an auxiliary fuel in some cement kilns. However, significant amounts of tire waste is illegally discharged in dumpin...
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Tire waste is discharged at 3 or 4 million wheels per year in Japan. Tire waste is mainly treated as an auxiliary fuel in some cement kilns. However, significant amounts of tire waste is illegally discharged in dumping sites, and causing an environmental pollution. In order to find a practical recycling method of this tire waste, a carbonization technique was investigated. Tire waste was heated at 300 degrees for 3 h. The tire was completely decomposed to gas, oil, charcoal and steel iron. The generated gas was separated in an oil separator, and incinerated as supplementary fuel. Generated oil was also separated in an oil separator and collected. The quality of the oil corresponded to kerosene or light oil can be used as a fuel.
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