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Case Reports in Clinical Medicine 2016年第9期5卷 335-341页

作者： Yoshiro Imai Ryo Iida Masahiko nitta Akira Takasu Department of Emergency Medicine Osaka Medical College Osaka Japan

A previously healthy 53-year-old woman was urgently hospitalized due to septic shock. She was diagnosed with bacterial pneumonia based on chest radiograph and computed tomography findings of right upper lobe consolidation. Sputum Gramstain at the time of admission showed gram-negative rods with phagocytosis. Intravenous meropenem was immediately initiated as empiric antibacterial therapy. Bacterial culture specimens from sputum and blood were positive for Pseudomonas aeruginosa. Following appropriate antibiotic therapies, the patient recovered from a shock state and gradually became well. There has been no evidence of recurrence at 6 months after discharge. P. aeruginosa community acquired pneumonia with septicemia is rapidly progressive and often fatal. The choice of initial empiric antibiotic treatment that is active against P. aeruginosa is critical in improving outcome.

关键词： Pseudomonas aeruginosa Community Acquired Pneumonia Septicemia

A Response of Series Regulator to Incident High Frequency Noise on AC-mains

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A Response of Series Regulator to Incident High Frequency No...

A Filament-Associated Halo Coronal Mass Ejection

Asia-Pacific Conference on Environmental Electromagnetics CEEM’2000

作者： Atsuo Mutoh Shuichi nitta Tokyo University of Agriculture and Technology 2-24-16 Naka-cho Koganei Tokyo 184-8588 JAPAN Tokyo University of Agriculture and Technology 2-24-16 Naka-cho Koganei Tokyo 184-8588 JAPAN

＜正＞It is important in order to guaran-tee the stable operation of digital circuit tounderstand the response of power supply toincident high frequency *** this paper,a response of series regulator to incident highfrequency noise on AC-mains is analyticallyand experimentally *** a results,itis shown that high frequency response of se-ries regulator is influenced by the parasitic ca-pacitance between base and collector termi-nals of control transistor,the parasitic capaci-tance between negative-input and output ter-minals of operational amplifier,and the out-put impedance of operational amplifier.

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Chinese Journal of Astronomy and Astrophysics 2001年第1期1卷 85-98页

作者： Jun Zhang, Jingxiu Wang, and Nariaki nitta ( Beijing Astronomical Observatory, National Astronomical Observatories,Chinese Academy of Sciences, Beijing 100012 Lockheed Martin Solar and Astrophysics Laboratory, Palo Alto, CA 94304, USA) Beijing Astronomical Observatory National Astronomical Observatories Chinese Academy of Sciences Lockheed Martin Solar and Astrophysics Laboratory

There are only a few observations published so far that show the initiation of a coronal mass ejection (CME) and illustrate the magnetic changes in the surface origin of a CME. Any attempt to connect a CME with its local solar activities is meaningful. In this paper we present a clear instance of a halo CME initiation. A careful analysis of magnetograms shows that the only obvious magnetic changes in the surface region of the CME is a magnetic flux cancellation underneath a quiescent filament. The early disturbance was seen as the slow upward motion in segments of the quiescent filament. Four hours later, the filament was accelerated to about 50 km s-1 and erupted. While a small part of the material in the filament was ejected into the upper corona, most of the mass was transported to a nearby region. About forty minutes later, the transported mass was also ejected partially to the upper corona. The eruption of the filament triggered a two-ribbon flare, with post-flare loops connecting the flare ribbons. A halo CME, which is inferred to be associated with the eruptive filament, was observed from LASCO/C2 and C3. The halo CME contained two CME events, each event corresponded to a partial mass ejection of the filament. We suggest that the magnetic reconnection at the lower atmosphere is responsible for the filament eruption and the halo CME.

关键词： Sun: filament - Sun: magnetic fields-Sun: coronal mass ejection

Examination of Treatment Methods for a PEDOT:PSS Transparent Conductive Film Produced Using an Inkjet Method

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Advances in Materials Physics and Chemistry 2017年第8期7卷 311-322页

作者： Atsushi nitta Yuki Imamura Kazuya Kawahara Kazuhiro Takeda Department of Electronic Control Engineering National Institute of Technology Kagoshima College Kirishima Japan Advanced Mechanical and Electronic Systems Engineering National Institute of Technology Kagoshima College Kirishima Japan Department of Information Engineering National Institute of Technology Kagoshima College Kirishima Japan

Flexible devices manufactured using printed electronics have attracted the attention of many researchers. A high-performance transparent conductive film exhibiting high flexibility and elasticity is expected to be developed because of its need for the creation of flexible devices. An indium tin oxide (ITO) thin film, which has generally been used, has weaknesses such as fragility to bending stress and depletion of the resource. This study focused on poly (3, 4-ethy-lenedioxythiophene)/poly (styrenesulfonate) (PEDOT:PSS), a conductive polymer material, and examined improvement in the resistivity and transmittance of the transparent conductive film produced using an inkjet method. The present study improved the electrical and optical characteristics of the thin film by examining the annealing temperature between printing operations and the application method of a polar solvent. As a result, the resistivity and transmittance of a PEDOT:PSS thin film were 1.49 × 10-3 Ω·cm and 89.2%, respectively. This film was obtained by annealing at 90°C for 30 min and applying a polar solvent, using an inkjet printer, between printing operations. The printing was performed three times.

关键词： PEDOT:PSS Inkjet Printing Transparent Conductive Film Flexible Devices

Impact of Perioperative Management for Intracranial Arterial Stenosis on Postoperative Stroke Incidence in Coronary Artery Bypass Surgery: A Propensity Matching and Multivariate Analyses

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Surgical Science 2018年第9期9卷 311-324页

作者： Hajime Imura Yuji Maruyama Makoto Shirakawa Takashi nitta Department of Cardiovascular Surgery Nippon Medical School Musashikosugi Hospital Kawasaki Japan Nippon Medical School Hospital Tokyo Japan

Background: Intracranial arterial steno-occlusive lesion (IAS) is the most common cause of stroke. We hypothesized that adequate perioperative management for IAS is useful to prevent stroke in coronary artery bypass grafting (CABG). Methods: IAS was evaluated using magnetic resonance imaging/angiography (MRI/A, n = 216) in patients without a history of stroke or carotid stenosis (≥50%) in CABG between May 2005 and June 2018 (n = 424). Off-pump CABG was performed in most patients. Different perioperative managements of systolic arterial pressure (SAP) were applied for patients with and without MRI/A. SAP was strictly maintained at ≥80 mmHg in patients with significant IAS (≥50%, n = 28) and ≥90 mmHg for severe IAS (≥70%, n = 44) while SAP less than 80 mmHg (usually ≥70 mmHg) was allowed for patients without MRI/A. Intra-aortic balloon pumping was used for patients with multiple severe IAS and/or occlusion. Clinical outcomes were compared between patients with and without MRI/A. Propensity matching was performed (n = 181 each). Results: Complete revascularization was achieved in all patients. Nine patients (2.12%) had postoperative strokes;the incidence of stroke was signifi-cantly less in patients with preoperative MRI/A (n = 1, p = 0.016). There was no significant difference in the incidence of in-hospital mortality between patients with and without preoperative MRI/A (0.5% and 1.0%, respectively;p = 0.529). Multivariate analysis revealed that no preoperative MRI/A was the only significant predictors of postoperative stroke (p = 0.045). The incidence of stroke was not higher in patients with IAS who underwent MRI/A (p = 0.332). Conclusions: Preoperative evaluation of IAS using MRI/A and following our perioperative management significantly reduced perioperative stroke in patients undergoing CABG.

关键词： CABG Intracranial Arterial Stenosis Stroke Magnetic Resonance Imaging Off-Pump

Morphology and Mechanical Properties in Polypropylene-based Nanocomposites

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New Approaches in Risk Assessment of Drug and Food

第三届工程塑料国际学术研讨会

作者： Koh-hei nitta Takeshi Sako Department of Chemical Engineering Kanazawa University School of Materials Science JAIST

＜正＞Introduction Isotactic polypropylene exhibits an attractive combination of low cost, low weight and the extraordinary versatility in terms of properties, applications, and recycling. In order to improve the mech...

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中国药理学与毒理学杂志 2006年第3期 180-181页

作者： Hoonjeong Kwon Sumol Pavittranon Xiao-Bo Cen Atsumi nitta Li Wang Ying-Lan Zhao Toshitaka Nabeshima Anong Bintvihok Sarisak Soontornchai

W2-1 Safety assurance for the dietary supplement ingredients of plant origin Hoonjeong KWON(Department of Food and Nutrition and Research Institute of Human Ecology, Seoul National University, Seoul, Korea)Abstract:Dietary supplements need to show statistically sound evidence for the claimed health effect, and this often requires high dose of the material which in turn raises the safety concern regardless of whether it has been traditionally used or not, since it frequently exceeds the traditional use. HFF material can be derived from the traditional food sources, medicinal plants, or from novel materials. It can also be purified compound, whole crude extract, or in betweens. These wide spectra of HFF materials present the difficulties in introducing the unique safety assurance scheme.

关键词： LD New Approaches in Risk Assessment of Drug and Food

Usefulness of a Simple Protein-Energy Wasting Score for Predicting Hospitalization in Maintenance Hemodialysis Patients: A Prospective Cohort Study

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International Journal of Clinical Medicine 2021年第9期12卷 377-385页

作者： Yoko Watanabe Keiko Suzuki Fumiko Kojima Yoshiko Tanaka Kosaku nitta Shinjuku Ishikawa Clinic Tokyo Japan Department of Nephrology Tokyo Women’s Medical University Tokyo Japan

Background: Malnutrition is a strong predictor of prognosis in maintenance hemodialysis patients (MHD). We previously proposed a new and simple protein-energy wasting (PEW) score that appears to be useful for assessing the risk of mortality in patients on MHD. Objectives: In the present study, we evaluated the reliability of this PEW score as a predictor of hospitalization in Japanese patients on MHD. Methods: In this single-center, prospective cohort study conducted in Japan, PEW score was calculated for 180 MHD patients. PEW score ranged from 0 (best: S1) to 4 (worst: S4) and was calculated based on nutritional indicators including serum albumin, body mass index, serum creatinine level, and protein intake. The outcome was the number of hospitalizations during the 2-year study period. Results: Thirty-six patients were hospitalized during the study period. Kaplan-Meier curves showed there were fewer hospitalizations in the group with a PEW score of 0/1 than in the group with a score of 3/4. Multivariate analysis revealed a hazard ratio for hospitalization of 3.109 for S3/4 versus S0, 2.777 for S3/4 versus S1, and 2.048 for S3/4 versus S2. Conclusion: The new and simple PEW score is a useful predictor of hospitalization in MHD patients and is also useful for identifying subgroups of MHD patients with a high risk of mortality.

关键词： Protein-Energy Wasting Hemodialysis Hospitalization Simple Score

Long-Term Effect of Ferric Citrate Hydrate on Mineral Metabolism and Anemia in Maintenance Hemodialysis Patients

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International Journal of Clinical Medicine 2020年第11期11卷 719-730页

作者： Yuta Bando Mizuki Komatsu Masayuki Okazaki Hiroshi Kawaguchi Kosaku nitta Department of Nephrology Jyoban Hospital Fukushima Japan Department of Nephrology Tokyo Women’s Medical University Tokyo Japan

Background: Ferric citrate hydrate is a phosphate (P)-binder drug that is indicated for patients with chronic kidney disease (CKD) undergoing maintenance hemodialysis (MHD). Objectives: The objectives of this study were to evaluate the changes in the serum mineral metabolism biomarker levels and treatment status of anemia in MHD patients receiving ferric citrate hydrate. Methods: A total of 132 adult dialysis patients were enrolled in this study. Bone turnover marker levels, anemia status and iron biomarker levels over a period of 18 months after the start of the ferric citrate hydrate treatment were extracted from the medical records of the patients. Results: At enrollment, 14 (10.6%) patients were P-binder-naïve, and 118 (89.4%) patients were receiving other P-binders. The serum P level before the start of ferric citrate hydrate treatment was ≤5.5 mg/dL in 18.8% of the patients. After 18 months of ferric citrate hydrate treatment, the proportion of patients with serum P levels ≤ 5.5 mg/dL increased to 47.7%. The mean ± standard error of the mean (SEM) of the serum P level was 7.05 ± 0.14 mg/dL at the baseline, and decreased to 5.83 ± 0.17 mg/dL after 18 months of treatment with ferric citrate hydrate. The mean ± SEM of the serum hemoglobin (Hb), ferritin, and transferrin saturation (TSAT) levels were 11.96 ± 0.76 g/dL, 71.13 ± 6.09 ng/mL, and 25.19% ± 1.21%, respectively, at the baseline, and 11.45 ± 0.13 g/dL, 124.94 ± 8.62 ng/mL, and 26.18% ± 0.99%, respectively, after 18 months of ferric citrate hydrate treatment. Conclusions: These results suggest that the serum P and anemia biomarker levels observed in this study were similar to those reported in clinical trials.

关键词： Ferric Citrate Hydrate Hemodialysis Mineral Metabolism Anemia