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高能离子辐照的ODS铁素体刚硬化效应研究

IMP & HIRFL Annual Report 2017年第1期 121-123页

作者： Ding Zhaonan Zhang Chonghong Yang Yitao Song Yin Zhang Xianlong akihiko Kimura Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China Institute of Advanced Energy Kyoto UniversityKyotoJapan

Influence of the nanoscale oxide particles on mechanical properties and irradiation resistance of oxide-dispersionstrengthened(ODS)ferritic steels is of critical importance for the use of the material in fuel cladding or blanket components in advanced nuclear *** the present work,impact of structures of oxide dispersoids on the irradiation hardening of ODS ferritic steels was *** of three kinds of high-Cr ODS ferritic steels containing oxide dispersoids with different number density and average size were irradiated with high-energy Niions at about−50℃.The energy of the incident Ni ions was varied from 12.73 to 357.86 MeV by using an energy degrader at the terminal so that a plateau of atomic displacement damage(∼0.8 dpa)was produced from the near surface to a depth of 24m in the specimens.

关键词： cladding resistance energy

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He离子注入ODS钢中硬化效应研究

IMP & HIRFL Annual Report 2017年第1期 125-127页

作者： Su Changhao Zhang Chonghong Yang Yitao Ding Zhaonan Chen Yuguang and akihiko Kimura Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China University of Chinese Academy of Science Beijing 100049China Institute of Advanced Energy Kyoto UniversityUjiKyoto 611-0011Japan

In advanced nuclear reactors,helium can inevitably be produced via(n,)reaction and may precipitate into nano-scale helium bubbles in materials,and can causes degradation of material *** the present study,effects of helium bubbles formation in an oxide dispersion strengthened(ODS)steel is *** of an ODS ferritic steel(15Cr-4Al-0.6Zr-0.1Ti)were implanted with mutiple-energy He ions at room temperature at the terminal of the 320 kV High-voltage Platform in IMP,to create a damage plateau of 0.4 dpa for average(corresponding to an He concentration of about 7000 appm)from the near surface to a depth about 1*** specimen was subsequently thermally annealed at 800℃for 1 h in vacuum so that simple defects formed in the as-implanted state underwent significant recombination,meanwhile helium bubbles at nano-scale were formed.

关键词： steel strengthened annealed

Calcitriol-induced hypercalcemia in a patient with granulomatous mycosis fungoides and end-stage renal disease

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World Journal of Nephrology 2013年第2期2卷 44-48页

作者： Takamasa Iwakura Naro Ohashi Naoko Tsuji Yoshitaka Naito Shinsuke Isobe Masafumi Ono Tomoyuki Fujikura Takayuki Tsuji Yukitoshi Sakao Hideo Yasuda akihiko Kato Toshiharu Fujiyama Yoshiki Tokura Yoshihide Fujigaki First Department of Medicine Hamamatsu University School of Medicine Higashi-ku Hamamatsu 431-3192 Japan Blood Purification Unit Hamamatsu University School of Medicine Higashi-ku Hamamatsu 431-3192 Japan Department of Dermatology Hamamatsu University School of Medicine Higashi-ku Hamamatsu 431-3192 Japan

An 86-year-old man, diagnosed as having mycosis fungoides in May 2008 and treated with repeated radiation therapy, was admitted to our hospital for initiation of hemodialysis due to end-stage renal disease(ESRD) in April 2012. On admission, his corrected serum calcium level was 9.3 mg/d L, and his intact parathyroid hormone level was 121.9 pg/mL(normal range 13.9-78.5pg/mL), indicating secondary hyperparathyroidism due to ESRD. After starting hemodialysis, urinary volume diminished rapidly. The serum calcium level increased(12.7 mg/dL), and the intact parathyroid hormone level was suppressed(< 5 pg/m L), while the 1,25-dihy-droxyvitamin D3(calcitriol) level increased(114 pg/mL, normal range: 20.0-60.0 pg/m L) in June 2012. The possibilities of sarcoidosis and tuberculosis were ruled out. Skin biopsies from tumorous lesions revealed a diagnosis of granulomatous mycosis fungoides. The serum soluble interleukin-2 receptor levels and the degrees of skin lesions went in parallel with the increased serum calcium and calcitriol levels. Therefore, the patient was diagnosed as having calcitriol-induced hypercalcemia possibly associated with granulomatous mycosis fungoides. Granulomatous mycosis fungoides is rare, and its association with calcitriol-induced hypercalcemia has not been reported. Careful attention to calcium metabolism is needed in patients with granulomatous mycosis fungoides, especially in patients with ESRD.

关键词：血液透析肾病治疗方法临床分析

An Earth-mass planet in a time of COVID-19:KMT-2020-BLG-0414Lb

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Research in Astronomy and Astrophysics 2021年第9期21卷 243-261页

作者： Weicheng Zang Cheongho Han Iona Kondo Jennifer C.Yee Chung-Uk Lee Andrew Gould Shude Mao Leandro de Almeida Yossi Shvartzvald Xiangyu Zhang Michael D.Albrow Sun-Ju Chung Kyu-Ha Hwang Youn Kil Jung Yoon-Hyun Ryu In-Gu Shin Sang-Mok Cha Dong-Jin Kim Hyoun-Woo Kim Seung-Lee Kim Dong-Joo Lee Yongseok Lee Byeong-Gon Park Richard W.Pogge John Drummond Thiam-Guan Tan JoséDias do Nascimento Júnior Dan Maoz Matthew T.Penny Wei Zhu Ian A.Bond Fumio Abe Richard Barry David P.Bennett Aparna Bhattacharya Martin Donachie Hirosane Fujii akihiko Fukui Yuki Hirao Yoshitaka Itow Rintaro Kirikawa Naoki Koshimoto Man Cheung Alex Li Yutaka Matsubara Yasushi Muraki Shota Miyazaki Greg Olmschenk Clément Ranc Nicholas J.Rattenbury Yuki Satoh Hikaru Shoji Stela Ishitani Silva Takahiro Sumi Daisuke Suzuki Yuzuru Tanaka Paul J.Tristram Tsubasa Yamawaki Atsunori Yonehara Andreea Petric Todd Burdullis Pascal Fouqué Department of Astronomy Tsinghua UniversityBeijing 100084China Department of Physics Chungbuk National UniversityCheongju 28644Republic of Korea Department of Earth and Space Science Graduate School of ScienceOsaka UniversityToyonakaOsaka 560-0043Japan Center for Astrophysics j Harvard&Smithsonian 60 Garden St.CambridgeMA 02138USA Korea Astronomy and Space Science Institute Daejon 34055Republic of Korea University of Science and Technology Korea(UST)217 Gajeong-ro Yuseong-guDaejeon 34113Republic of Korea Max-Planck-Institute for Astronomy Königstuhl 1769117 HeidelbergGermany Department of Astronomy Ohio State University140 W.18th Ave.ColumbusOH 43210USA National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China Universidade Federal do Rio Grande do Norte(UFRN) Departamento de F´1sica59078-970NatalRNBrazil Department of Particle Physics and Astrophysics Weizmann Institute of ScienceRehovot 76100Israel University of Canterbury Department of Physics and AstronomyPrivate Bag 4800Christchurch 8020New Zealand School of Space Research Kyung Hee UniversityYonginKyeonggi 17104Republic of Korea Possum Observatory PatutahiGisbourneNew Zealand Perth Exoplanet Survey Telescope PerthAustralia School of Physics and Astronomy Tel-Aviv UniversityTel-Aviv 6997801Israel Department of Physics and Astronomy Louisiana State UniversityBaton RougeLA 70803 USA Canadian Institute for Theoretical Astrophysics University of Toronto60 St George StreetTorontoON M5S 3H8Canada Institute of Natural and Mathematical Sciences Massey UniversityAuckland 0745New Zealand Institute for Space-Earth Environmental Research Nagoya UniversityNagoya 464-8601Japan Code 667 NASA Goddard Space Flight CenterGreenbeltMD 20771USA Department of Astronomy University of MarylandCollege ParkMD 20742USA Department of Physics University of AucklandPrivate Bag 92019AucklandNew Zealand Department of Earth and Planetary Science Graduate School of ScienceThe University of Tokyo7-3-1 Hongo

We report the discovery of KMT-2020-BLG-0414 Lb,with a planet-to-host mass ratio q2=0.9-1.2×10-5=3-4 q⊕at 1σ,which is the lowest mass-ratio microlensing planet to *** with two other recent discoveries(4?q/q⊕?6),it fills out the previous empty sector at the bottom of the triangular(log s,log q)diagram,where s is the planet-host separation in units of the angular Einstein radiusθ***,these discoveries call into question the existence,or at least the strength,of the break in the mass-ratio function that was previously suggested to account for the paucity of very low-q *** to the extreme magnification of the event,Amax~1450 for the underlying single-lens event,its light curve revealed a second companion with q3~0.05 and|log s3|~1,i.e.,a factor~10 closer to or farther from the host in *** measurements of the microlens parallaxπE and the angular Einstein radiusθE allow estimates of the host,planet and second companion masses,(M1,M2,M3)~(0.3 M⊙,1.0 M⊕,17 MJ),the planet and second companion projected separations,(a⊥,2,a⊥,3)~(1.5,0.15 or 15)au,and system distance DL~1 *** lens could account for most or all of the blended light(I~19.3)and so can be studied immediately with high-resolution photometric and spectroscopic observations that can further clarify the nature of the *** planet was found as part of a new program of high-cadence follow-up observations of high-magnification *** detection of this planet,despite the considerable difficulties imposed by COVID-19(two KMT sites and OGLE were shut down),illustrates the potential utility of this program.

关键词： gravitational lensing:micro

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梭鱼卵黄蛋白原的化学发光免疫检测法

水产学报 2010年第4期34卷 572-580页

作者：吴美琴和田竜典罗雯姝盛田祐加平松尚志原彰彦钟俊生上海海洋大学水产与生命学院日本北海道大学水产学部

运用建立化学发光免疫(chemiluminescence immunoassay,CLIA)检测法,对梭鱼血清中主要卵黄蛋白原(Vg)类型(B类型;VgB)进行定量测定。梭鱼VgBCLIA法按两步法操作进行,使用纯化的梭鱼VgB制备特异型抗血清(a-VgB)。优化抗体浓度和培育时间... 详细信息

运用建立化学发光免疫(chemiluminescence immunoassay,CLIA)检测法,对梭鱼血清中主要卵黄蛋白原(Vg)类型(B类型;VgB)进行定量测定。梭鱼VgBCLIA法按两步法操作进行,使用纯化的梭鱼VgB制备特异型抗血清(a-VgB)。优化抗体浓度和培育时间等检验条件后,检验范围设定为3.91～500ng/mL。卵黄发生期的梭鱼雌鱼血清和雌激素处理后的梭鱼稚鱼血清稀释曲线与纯化的梭鱼Vg曲线平行,而梭鱼雄鱼稀释血清中几乎不发生相应的免疫学反应。对天津原种场养殖的10尾梭鱼血清VgB水平的定量检测结果表明,在雌鱼(9尾)血清中检测到VgB但个体间差异较大,变化范围为3.0～2700.1μg/mL,并表现出随着卵巢发育而增长的变化趋势。相对而言,成熟梭鱼雄鱼血清VgB水平则极低(2.7μg/mL),表明在其生长环境中不存在雌激素活性。另外,所有个体的组织学观察也未呈现出明显的性腺异常情况。研究为梭鱼主要雌激素诱导生物标志物(VgB)的量化提供了一种新的手段,较以往的检验方法具有更高的灵敏度,有助于建立多元化的水生环境中雌激素活性的检测体系。

关键词：梭鱼生物标志物卵黄蛋白原化学发光免疫雌激素

媒介动物(蚊、猪)体内黄病毒分子流行病学调查研究

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中国国境卫生检疫杂志 2007年第5期30卷 267-272页

作者：马洪波前田秋彦孙虹柯昌文杜坚谭华姚若东高岛郁夫柯明剑郑夔王遇春前田润子曾新宇冯子力珠海出入境检验检疫局珠海519010 日本北海道大学研究院兽医学研究部广东省疾病预防控制中心广州510300

〔目的〕通过对珠海注册养猪场及珠海口岸地区的蚊虫体内黄病毒的带毒率、宿主动物(猪群)及其人群进行血清黄病毒类(日本脑炎、登革热等)抗体水平的调查研究,为控制黄病毒在人群中的流行提供科学依据。〔方法〕采集养猪场猪血清、养猪... 详细信息

〔目的〕通过对珠海注册养猪场及珠海口岸地区的蚊虫体内黄病毒的带毒率、宿主动物(猪群)及其人群进行血清黄病毒类(日本脑炎、登革热等)抗体水平的调查研究,为控制黄病毒在人群中的流行提供科学依据。〔方法〕采集养猪场猪血清、养猪场和口岸蚊标本、养猪场从业人员、入境的东南亚船员和城区部分发热病人血清,采用酶联免疫吸附试验(ELISA)法分别检测猪群和人群血清中的日本脑炎、登革热抗体;使用紫外灯诱蚊法在养猪场和口岸捕捉蚊类,经鉴定种类后,按20只蚊一组制成蚊悬液后,采用细胞培养、逆转录-聚合酶链反应(RT-PCR)以及荧光定量PCR技术检测蚊体内日本脑炎病毒、登革和西尼罗病毒等黄病毒的携带情况。〔结果〕1.猪血清日本脑炎病毒IgG抗体:结果已发表于《中国国境卫生检疫杂志》2007年第3期《珠海市部分注册猪场日本脑炎调查研究》。2.蚊媒带毒情况检测:2005年1月～2006年12月共捕获的2763只成蚊,经鉴定隶属4属8种,其中白纹伊蚊所占比例最高(32.75%),其次为致倦库蚊(26.06%)、三带喙库蚊(25.30%)、海滨库蚊(7.75%)、中华按蚊(3.84%)、骚扰阿蚊(3.18%),其他(常型曼蚊和巨型阿蚊等)(1.12%);在132组蚊研磨液的病毒细胞培养中,有7份标本出现CPE病变,使用黄病毒通用引物,RT-PCR反应能扩增出相应的阳性条带,其中白纹伊蚊组阳性3份,致倦库蚊组阳性3份,三带喙库蚊组阳性1份,但用日本脑炎病毒、登革病毒Ⅰ～Ⅳ型和西尼罗病毒等特异性引物,未能扩增出相应的阳性条带,说明可能存在着其它黄病毒类的病毒感染;采用荧光定量PCR法,对蚊悬液和细胞培养液日本脑炎、登革和西尼罗病毒进行检测,从1组海滨库蚊标本中检出日本脑炎病毒核酸阳性,但强度较弱,这与珠海地区是乙脑低发地区相一致。3.人群登革热和日本脑炎血清抗体检测:从东南亚的入境船员、本地发热病人和养猪场从业人员等血清标本511份中,登革病毒抗体IgG总阳性率为7.24%,其中以东南亚的入境船员的阳性率最高,为12.76%,没有检出登革病毒抗体IgM和日本脑炎IgM抗体。〔结论〕珠海地区存在日本脑炎的主要传播媒介,并且在蚊媒中携带有日本脑炎病毒;蚊标本细胞培养出现细胞病变和RT-PCR扩增出黄病毒基因的特异性片段,提示在捕获蚊标本中可能存在着其他病毒感染的可能;虽然养猪场猪群日本脑炎感染率不高,但存在着日本脑炎病毒的隐性感染或曾经感染过,提示不能够放松对乙型脑炎的预防控制工作,应采取积极的预防措施,防止人群和猪场日本脑炎的发生与流行。此外,研究结果表明东南亚船员有较高的登革热感染率,因此,在登革热流行期间,我国口岸应加强对来自东南亚国家交通工具员工和旅客的登革热的监测,以及有可能藏带、孳生蚊虫的废旧物品、集装箱等的检验检疫工作,以防止登革热的传入与流行。

关键词：蚊猪黄病毒带毒率血清抗体

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