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1999中国造纸学会学术报告会

作者： Masood akhtar Gary M．Scott Ross E．Swaney Mike J．Lentz Eric G．Horn Marguerite S．Sykes Gary C．Myers 关颖

机械制浆是一个耗电量较大的制浆过程,而且成纸强度较差。生物机械制浆就是在机械制浆前,用菌种对木素纤维素物质进行预处理。实验证明菌种预处理后再进行机械制浆至少可节约30％左右的电能,而且成纸强度也大为改善。为了把生物机械制...

机械制浆是一个耗电量较大的制浆过程,而且成纸强度较差。生物机械制浆就是在机械制浆前,用菌种对木素纤维素物质进行预处理。实验证明菌种预处理后再进行机械制浆至少可节约30％左右的电能,而且成纸强度也大为改善。为了把生物机械制浆工艺应用到工业生产中,我们采用最优质的生物制浆菌种连续接种50 吨云杉木片,然后把它们置于室外,堆放两个星期。木片堆需要进行强制通风,以保持菌种最优的生长温度和木片堆的水分。随后用对照木片和菌种预处理木片进行热磨机械法制TMP浆,生产低定量涂布纸。与对照木片相比,用菌种预处理的木片进行机械制浆可节约33％的电能,而且成纸的强度特性也大大提高。与传统TMP浆相比,生物机械浆的纤维强度较好。因此,在成纸中至少可减少5％的漂白针叶木硫酸盐浆。但是,用菌种预处理木片却降低了成浆白度,成浆白度的降低可通过漂白时增加过氧化氢用量来得到弥补。如果达到与对照漂白浆相同的白度,那么需要多加60％的过氧化氢。生物机械制浆的经济性很有吸引力。

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患胶滴样角膜营养不良的发育迟缓儿童1例:临床病理学特征和MISI基因排除

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世界核心医学期刊文摘（眼科学分册） 2005年第8期1卷 49-49页

作者： akhtar S. Bron A.J. 司冰心 School of Optometry/Vision Sciences Cardiff University Redwood Bldg. Kings Edward VII Ave. Cardiff CF10 3NB United Kingdom

Aims: Gelatinous drop-like corneal dystrophy (GDLD) is an early-onset, autos omal recessive condition characterised by amyloid deposits within the cornea. We report the histopathological and molecular genetic findings in a Caucasian chil d with GDLD who also exhibited global developmental delay. Methods: Bilateral la mellar keratoplasty was carried out at age 6 and 7 years. Tissue was fixed for l ight and electron microscopy, including immunoelectronmicroscopy. The coding reg ion of the M1S1 gene was screened for mutations in the affected proband and avai lable relatives, using DNA extracted from mouthwashes. Results: Nodular deposits , which were present subepithelially and in the central superficial stroma, stai ned typically for amyloid with PAS and Congo red. A nodular deposit of amyloid, together with large amounts of lactoferrin and sparse amounts of keratoepithelin (βig-h3), was present in the central superficial stroma, causing destruction of Bowman’s layer and elevation of the thinned, degenerate epithelium. Around t he deposit zone, the stroma exhibited large numbers of thick filamentous proteog lycan deposits. While the affected child was homozygous for a novel A1133 C sing lenucleotide polymorphism (SNP) that resulted in an aspartic acid to alanine sub stitution at position 173 of the M1S1 coding sequence, this polymorphism was als o found at relatively high frequency in a sample of normal controls, enabling ex clusion of the M1S1 gene as the disease locus. Conclusion: Increased epithelial permeability in GDLD may be explained in part by an altered membrane permeabilit y of the superficial epithelial cells. An association with developmental delay h as not been reported previously.

关键词：角膜营养不良 MISI 临床病理学特征沉着物角膜上皮基质层板层角膜移植术淀粉样先证者电镜检查

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