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材料科学与工程（中英文B版） 2013年第11期3卷 721-733页

作者： Xiaoguang Xue Guoxi Li Adam James Sobey ramanand ajit Shenoi School of Mechatronic Engineering and Automation National University of Defense Technology Changsha 410073 China Faculty of Engineering and the Environment University of Southampton Southampton SO17 1B J UK

Stiffened composite panels are used within many applications, from aerospace to marine applications. Stiffened panels are utilized for their high strength to weight ratio and flexibility of layups while counteracting the low stiffness exhibited by composites. Complications arise when attempting to utilize the full variability of layups in conjunction with reliability constraints creating a complex design problem when constrained by both buckling and material strength. To aid the process of optimizing the design of composite structures and layups, while ensuring a low mass, this paper presents a bi-level optimization scheme for minimization of the weight of tophat stiffened composite panels with probabilistic deflection constraints. To improve the computational efficiency, an energy based grillage method is formulated and applied for the investigation of buckling problems under bi-directional in-plane loads. The method is validated by comparing the results obtained from FE model calculations. The variables that have a large impact on the structural safety have been identified by both safety index and COV based reliability analysis. A parametric study of plate dimensions and loading ratios is conducted to investigate the coupling effects on critical buckling load. The method presented in this paper, makes it possible for engineers to improve their designs, at an early stage, with an integrated consideration between product performance and design parameters.

关键词：复合材料加筋板可靠性优化应用程序屈曲荷载复合材料结构屈曲临界载荷设计问题计算效率

Effect of Ensiling on Nutritional Properties of Sericea Lespedeza Alone or in Mixtures with Alfalfa

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Journal of Agricultural Science and Technology(A) 2019年第5期9卷 310-322页

作者： Anil Singh Vicki Owen Gregory Dykes Harley Naumann ajit Mahapatra Thomas Terrill College of Agricultural Family Sciencesand TechnologyFort Valley State UniversityFort ValleyGA 31030USA Division of Plant Sciences University of MissouriColumbiaMO 65211USA

In this investigation,fresh sericea lespedeza(SL;Lespedeza cuneata)and alfalfa(Medicago sativa)were cut in the field,frozen,chopped and mixed into ratios of 100:0,75:25,50:50,25:75 and 0:100,respectively,with each treatment combination packed into 12 mini-silos and sealed to be *** mini-silos per treatment were opened after 1,7,21 and 84 d of ensiling and analyzed for pH,neutral detergent fiber(NDF),acid detergent fiber(ADF),and acid detergent lignin(ADL),unbound and bound condensed tannins(CT),nitrogen(N),nitrate N(NO3-N),and ammonia N(NH4+N)*** of the forage combinations ensiled well,with a rapid drop in pH(below 5.0 by Day 7).Fiber concentrations(NDF,ADF,ADL)were greater in 75% and 100% SL silages than in 0%,25% and 50% SL samples by Day 84 of the study,possibly due to interference of CT in the detergent analysis *** of N,NO3-N and NH4+N were decreased in silages as percentage SL in the mixture increased,while unbound,bound and total CT increased as percentage SL *** this study,there was reduced proteolysis during ensiling of combinations of SL and alfalfa,as indicated by reduced NO3-N and NH4+N production as percentage SL in the silage mixtures increased.

关键词： Alfalfa condensed tannins ensiling sericea lespedeza

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rackspace:用户体验最关键

软件和信息服务 2015年第5期 15-页

作者： ajit Melarkode rackspace亚太区

'互联网+'已成为各行各业探讨最热的话题,而用户体验是最关键因素。作为管理式云公司,rackspace曾在亚太区对1200名、年龄在22~44岁之间的消费者做调查,了解他们使用电子商务平台的习惯。超过20%的受访者表示,当企业的网络平台出现问题... 详细信息

'互联网+'已成为各行各业探讨最热的话题,而用户体验是最关键因素。作为管理式云公司,rackspace曾在亚太区对1200名、年龄在22~44岁之间的消费者做调查,了解他们使用电子商务平台的习惯。超过20%的受访者表示,当企业的网络平台出现问题时,他们会直接关闭并跳到另一网站;超过90%的受访者认为,如果厂商的网站时常出现问题,他们会逐渐失去对该企业的信心并留下负面印象。

关键词：用户体验 rackspace 电子商务平台理式公司收益流量管理网络平台全球电子商务流畅度

Treatment Outcomes of Germ Cell Tumors of Ovary:Single Institutional Study

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Journal of Oncology research 2021年第1期3卷 17-21页

作者： rohit Kumar Jha ajit Kumar Kushwaha Mukunda Kumar Sunaina Wadhwa Sumedha Gargy Department of surgical oncology Rajendra Institute of Medical SciencesRanchi Department of Biochemistry All India Institute of Medical SciencesPatna Ex-fellow Department of Gynaecological OncologyTMCKolkata

5%of all ovarian tumours are accounted to germ cell tumours(GCT’s).Affecting mostly young women,the highest incidence is seen in second and third decade of *** are highly malignant but chemosensitive and more curable than their epithelial *** these tumors with effective surgery and combination chemotherapy survival rates have dramatically improved in recent *** present our experience of ovarian germ cell tumours in the department of Surgical Oncology,rajendra Institute of Medical Sciences(rIMS),ranchi with special emphasis on treatment outcomes.A retrospective review of hospital medical records of patients with ovarian germ cell tumours diagnosed and treated at rIMS from June 2019 to August 2020,was *** profile and treatment outcome of patients were recorded.A total of 19 patients met *** median age at diagnosis was 20 years(range 11-42 years)and all had good performance *** except two patients underwent surgery,70.6%and 29.4%in upfront and interval debulking surgery(IDS)setting *** preserving surgery was done in 75%patients in the primary surgery group and 60%undergoing IDS.83.3%patients received BEP as adjuvant chemotherapy whereas 80%as neo-adjuvant ***(31.5%)patients had dysgerminoma as final histology,followed by mixed histology(26.3%),yolk sac tumour(15.7%),immature teratoma(15.7%)and choriocarcinoma(10.5%).47.3%patients were in Stage I at the time of diagnosis.78.9%patients were alive without disease,10.5%recurred,and 10.5%were lost to follow up.

关键词： Germ cell tumour Dysgerminoma BEP Fertility sparing surgery Yolk sac tumour

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新型膜韧膏治疗急性软组织损伤临床观察

上海中医药杂志 2003年第7期37卷 34-35页

作者：谢路平武镇忆张琥石关桐强生(中国)有限公司上海200245 上海中医药大学附属曙光医院上海200021

为比较用不同溶媒、不同提取方法制备的新型膜韧膏对急性软组织损伤的临床疗效 ,将原膜韧膏 (红花、当归等组成 )制成橡皮膏和凝胶膏两种新剂型 ,用于治疗急性软组织损伤 78例 ,疗程 4天 ,于治疗后第 2天和第 4天观察疼痛、压痛、肿胀... 详细信息

为比较用不同溶媒、不同提取方法制备的新型膜韧膏对急性软组织损伤的临床疗效 ,将原膜韧膏 (红花、当归等组成 )制成橡皮膏和凝胶膏两种新剂型 ,用于治疗急性软组织损伤 78例 ,疗程 4天 ,于治疗后第 2天和第 4天观察疼痛、压痛、肿胀和功能障碍等症状变化。结果 :新型膜韧膏能有效地减轻症状 ,其中凝胶膏剂疗效相对较好。

关键词：新型膜韧膏急性软组织损伤临床观察中医药疗法

Functioal studies of MLC1 gene novel variants in six Chinese patients with megalencephalic leukoencephalopathy with subcortical cysts

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Functioal studies of MLC1 gene novel variants in six Chinese...

2010年世界胃肠病学组织关于炎症性肠病诊断和治疗的实践指南

中国神经科学学会第四次会员代表大会暨第八届全国学术会议

作者： Jing-Min WANG~(1 #) ajit Sigh Dhauchak~(2 #) Hong-En WEI~3 Hui XIONG~1 Ye WU~1 David Colman~2 Xi-ru WU~1 Yu-Wu JIANG~(1 *) 1 Department of Pediatrics Peking University First Hospital Beijing China 2 Montreal Neurological Institute Montreal Quebec Canada 3 Shanxi Medical University Taiyuan China

＜正＞Objective Megalencephalic leukoencephalopathy with subcortical cysts（MLC,MIM# 604004） is an autosomal recessively inherited disease resulting from a deficiency of MLC 1 *** previous data about this gene mutation in China have been *** objective was to identify and analyze MLC1 mutations in six Chinese patients with（MLC） and functional studies of MLC1 gene novel *** Direct DNA sequencing,Immunoblots,and *** Patient 1 was identified compound heterozygous mutations which one allele with the c. 218G＞A（p.G73E） missense mutation in exon 3 and the other allele with the c.772-1 G＞C splicing mutation in *** 2 was with the c.823G＞A（p.A275T） in exon 10 and the same splicing mutation with patient *** 3 was a homozygous mutation at c.772-1 G＞C in *** 4 was identified to be one allele with the c.593delCTCA（p.Y198X） in exon 7,and the other allele with the c.*48A＞T in 3’*** 5 and 6 were both with the same heterozygous variation c.65G＞A（p. r22Q） in exon 2,and the other allele with the c.206C＞T（p.S69L） in exon 3 for patient 5 and with the c.512G＞T（p.C171P） in exon 6 for patient *** immunostained transfected arstrocyte cells for HA-MLC1 and calnexin,an Er *** MLC1 was at astrocyte borders,whereas MLC 1 mutants G73E and Y198X are mainly intracellularly localized,except for A275T, which mainly at cell *** blot analysis in arstrocyte cells transfected with WT MLC1 and with the amino acid changes G73E,Y198X and A275T,in comparison with the WT MLC1 in MLC1 expression,G73E mutation showed a reduced protein expression in transfected astrocytes,Y198X reduced at 36kDa and showed a band at about 25kDa in artrocyte cells,and no changes were observed for the *** Eight DNA variations of MLC 1 gene were identified:three novel missense mutations（p.r22Q,p.G73E,and p.A275T）,one novel splicing mutation（c.772-1 G＞C in IVS9-1）,one known nonsense mutation（p.Y198X）,one known missense

关键词： Megalencephalic leukoencephalopathy with subcortical cysts MLC1 mutation

来源： cnki会议评论

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胃肠病学 2010年第9期15卷 548-558页

作者： Charles N.Bernstein Michael Fried J.H.Krabshuis Henry Cohen r.Eliakim Suleiman Fedail richard Gearry K.L.Goh Saheed Hamid Aamir Ghafor Khan A.W.LeMair Malfertheiner Qin Ouyang J.F.rey ajit Sood Flavio Steinwurz Ole O.Thomsen Alan Thomson Gillian Watermeyer 杨钊斌杨川华钱本余

炎症性肠病(IBD)是一组特发性、慢性、炎症性肠道疾病状态,包括两种主要类型:克罗恩病(CD)和溃疡性结肠炎(UC),两者的临床和病理特征既有重叠又有区别。IBD过去常见于发达国家,近几十年,发展中国家的患病率逐步上升。本指南就IBD诊断和... 详细信息

炎症性肠病(IBD)是一组特发性、慢性、炎症性肠道疾病状态,包括两种主要类型:克罗恩病(CD)和溃疡性结肠炎(UC),两者的临床和病理特征既有重叠又有区别。IBD过去常见于发达国家,近几十年,发展中国家的患病率逐步上升。本指南就IBD诊断和治疗方面提出的独特议题在当前的文献和指南中几乎从未被提及。由于各地区的IBD临床特点差异较大,因此根据患者的主诉诊断IBD或评估疾病活动度需随地区的变化而变化。同样,治疗亦应根据疾病的分类和当地医疗资源进行调整。世界胃肠病学组织根据世界各国医疗资源的差异,采用级联方法制订了IBD的诊疗指南。

关键词：炎症性肠病克罗恩病溃疡性结肠炎实践指南级联

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“绝对律令”视角下的强可持续性辩护

南京林业大学学报（人文社会科学版） 2018年第4期18卷 55-63页

作者：潘科基尼.穆利亚阿吉特.库尔马.毕贺拉萨里塔.卡尔魏婷印度矿业学院人文社会科学系北京大学马克思主义学院

"强可持续性"依赖于资源管理或自然资源保护原则,它认为自然环境或生态资本的某些形式是至关重要的,甚至可以说是无法替代的;自然生态环境对于所有生物的生存延续和福祉都有着自己的独特贡献。基于这种对强可持续性的理解,当代人类社会... 详细信息

"强可持续性"依赖于资源管理或自然资源保护原则,它认为自然环境或生态资本的某些形式是至关重要的,甚至可以说是无法替代的;自然生态环境对于所有生物的生存延续和福祉都有着自己的独特贡献。基于这种对强可持续性的理解,当代人类社会的当务之急就是大力保护我们生存其中的自然环境,因为目前自然生态环境的退化在许多方面已经超过它能自我修复的极限。强可持续性不但在伦理层面上提出了我们"如何做好正确的事"这一理论命题,而且强调了人类与自然环境之间的适当伦理关系。本文将从伊曼努尔·康德的"绝对律令"出发,为强可持续性进行辩护。康德的"绝对律令"包含三种公式或原则:普遍规律原则、人是目的的原则和自律原则。基于这种视角,只有人类才能从环境灾难中拯救自身,并使自然环境得到保护。鉴于当前的迫切形势,人类需要一种思维过程和道德实践上的更激进转变。"绝对律令"会激励每一个人出于责任而采取行动,而这种出于责任的行为才真正具有道德上的价值。保护自然环境涉及当代人和后代人的生计与福祉,是我们的一种道德责任。总之,"绝对律令"的原则在与弱可持续性方法作斗争的过程中是有用的,有助于我们从个人关切层面提升到全球关注层面来推动强可持续性。

关键词：强可持续性弱可持续性自然资本绝对律令直接责任间接责任

Decline in subarachnoid haemorrhage volumes associated with the first wave of the COVID- 19 pandemic

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Stroke & Vascular Neurology 2021年第4期6卷 542-552,I0026-I0032页

作者： Thanh N Nguyen Diogo C Haussen Muhammad M Qureshi Hiroshi Yamagami Toshiyuki Fujinaka Ossama Y Mansour Mohamad Abdalkader Michael Frankel Zhongming Qiu Allan Taylor Pedro Lylyk Omer F Eker Laura Mechtouff Michel Piotin Fabricio Oliveira Lima Francisco Mont'Alverne Wazim Izzath Nobuyuki Sakai Mahmoud Mohammaden Alhamza r Al-Bayati Leonardo renieri Salvatore Mangiafico David Ozretic Vanessa Chalumeau Saima Ahmad Umair rashid Syed Irteza Hussain Seby John Emma Griffin John Thornton Jose Antonio Fiorot rodrigo rivera Nadia Hammami Anna M Cervantes-Arslanian Hormuzdiyar H Dasenbrock Huynh Le Vu Viet Quy Nguyen Steven Hetts romain Bourcier romain Guile Melanie Walker Malveeka Sharma Don Frei Pascal Jabbour Nabeel Herial Fawaz Al-Mufti Atilla Ozcan Ozdemir Ozlem Aykac Dheeraj Gandhi Chandril Chugh Charles Matouk Pascale Lavoie randall Edgell Andre Beer-Furlan Michael Chen Monika Killer-Oberpfalzer Vitor Mendes Pereira Patrick Nicholson Vikram Huded Nobuyuki Ohara Daisuke Watanabe Dong Hun Shin Pedro SC Magalhaes raghid Kikano Santiago Ortega-Gutierrez Mudassir Farooqui Amal Abou-Hamden Tatsuo Amano ryoo Yamamoto Adrienne Weeks Elena A Cora rotem Sivan-Hoffmann roberto Crosa Markus Möhlenbruch Simon Nagel Hosam Al-Jehani Sunil A Sheth Victor S Lopez rivera James E Siegler Achmad Fidaus Sani ajit S Puri Anna Luisa Kuhn Gianmarco Bernava Paolo Machi Daniel G Abud Octavio M Pontes-Neto Ajay K Wakhloo Barbara Voetsch Eytan raz Shadi Yaghi Brijesh P Mehta Naoto Kimura Mamoru Murakami Jin Soo Lee Ji Man Hong robert Fahed Gregory Walker Eiji Hagashi Steve M Cordina Hong Gee roh Ken Wong Juan F Arenillas Mario Martinez-Galdamez Jordi Blasco Alejandro rodriguez Vasquez Luisa Fonseca M Luis Silva Teddy Y Wu Simon John Alex Brehm Marios Psychogios William J Mack Matthew Tenser Tatemi Todaka Miki Fujimura roberta Novakovic Jun Deguchi Yuri Sugiura Hiroshi Tokimura rakesh Khatri Michael Kelly Lissa Peeling Yuichi Murayama Hugh Stephen Winters Johnny Wong Mohamed Teleb Jeremy Payne Hiroki Fukuda Kosuke Miyake Junsuke Shimbo Yusuke Sug Neurology RadiologyBoston Medical CenterBostonMassachusettsUSA Neurology Marcus Stroke&Neuroscience CenterGrady Memorial HospitalEmory University School of MedicineAtlantaGAUSA radiology Radiation OncologyBoston University School of MedicineBostonMassachusettsUSA Neurology National Hospital Organization Osaka National HospitalOsakaJapan Neurosurgery National Hospital Organization Osaka National HospitalOsakaJapan Neurology Alexandria UniversityAlexandriaEgypt radiology Boston Medical CenterBostonMassachusettsUSA Department of Neurology Xinqiao HospitalChongqingChina Neurosurgery University of Cape TownRondeboschWestern CapeSouth Africa Neurosurgery Interventional NeuroradiologyClinica La Sagrada FamiliaBuenos AiresArgentina Neuroradiologie Neurologie VasculaireHospices Civils de LyonLyonAuvergne-Rhône AlpesFrance Neurologie Vasculaire Hospices Civils de LyonLyonAuvergne-Rhône AlpesFrance Interventional Neuroradiology Fondation Ophtalmologique Adolphe de RothschildParisÎle-de FranceFrance Neurology Hospital Geral de FortalezaFortalezaBrazil Interventional Neuroradiology Hospital Geral de FortalezaFortalezaBrazil Neuroradiology Nottingham University Hospitals NHS TrustNottinghamUK Department of Neurosurgery Kobe City Medical Center General HospitalKobeHyogoJapan Interventional Neurovascular Unit University Hospital CareggiFirenzeToscanaItaly Neuroradiology University Hospital Centre ZagrebZagrebCroatia Interventional Neuroradiology Hopital BicetreLe Kremlin-BicetreFrance Stroke and Interventional Neuroradiology Lahore General HospitalLahorePakistan Neurological Institute Cleveland Clinic Abu DhabiAbu DhabiUAE Department of radiology Beaumont HospitalDublinIreland Neurology Stroke UnitHospital-Estadual CentralVitoriaBrazil Neuroradiology Instituto de Neurocirugia Dr AsengoSantiagoChile Interventional Neuroradiology Institut National de NeurologieTunisTunisia Neurology Boston Medical CenterBostonMassachusettsUSA Neurosurgery Boston Medical Center

Background During the COVID-19 pandemic,decreased volumes of stroke admissions and mechanical thrombectomy were *** study’s objective was to examine whether subarachnoid haemorrhage(SAH)hospitalisations and ruptured aneurysm coiling interventions demonstrated similar *** We conducted a cross-sectional,retrospective,observational study across 6 continents,37 countries and 140 comprehensive stroke *** with the diagnosis of SAH,aneurysmal SAH,ruptured aneurysm coiling interventions and COVID-19 were identified by prospective aneurysm databases or by International Classification of Diseases,10th revision,*** 3-month cumulative volume,monthly volumes for SAH hospitalisations and ruptured aneurysm coiling procedures were compared for the period before(1 year and immediately before)and during the pandemic,defined as 1 March-31 May *** prior 1-year control period(1 March-31 May 2019)was obtained to account for seasonal *** There was a significant decline in SAH hospitalisations,with 2044 admissions in the 3 months immediately before and 1585 admissions during the pandemic,representing a relative decline of 22.5%(95%CI−24.3%to−20.7%,pruptured aneurysms declined with 1170-1035 procedures,respectively,representing an 11.5%(95%CI−13.5%to−9.8%,p=0.002)relative *** analysis was noted for aneurysmal SAH hospitalisation decline from 834 to 626 hospitalisations,a 24.9%relative decline(95%CI−28.0%to−22.1%,prelative increase in ruptured aneurysm coiling was noted in low coiling volume hospitals of 41.1%(95%CI 32.3%to 50.6%,p=0.008)despite a decrease in SAH admissions in this *** There was a relative decrease in the volume of SAH hospitalisations,aneurysmal SAH hospitalisations and ruptured aneurysm embolisations during the COVID-19 *** findings in SAH are consistent with a decrease in other emergencies,such as stroke and myocardial infarction.

关键词： diagnosis representing subarachnoid