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Classification and management of community forests in Indian Eastern Himalayas:implications on ecosystem services,conservation and livelihoods

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Ecological Processes 2018年第1期7卷 297-311页

作者： Ranjay K.singh Shah M.Hussain T.Riba Anshuman singh Egul Padung Orik Rallen Y.J.Lego ajay kumar Bhardwaj College of Horticulture and Forestry Central Agricultural UniversityPasighatArunachal Pradesh 791102India ICAR-Central Soil Salinity Research Institute KarnalHaryana 132001India Doying Gumin College East SiangPasighatArunachal PradeshIndia Pasighat India

Introduction:Evidence is mounting that traditional knowledge can play a critical role in shaping the biodiversity conservation strategies and maintaining ecosystem *** study was conducted with Adi community of Arunachal Pradesh(Ar P)state in the Eastern Indian Himalayas to understand as how local systems of forest classification governs conservation tradition and influences subsistence *** Adi villages were sampled from East Siang district of Ar P.A total of 197 men and 204 women(total of 401)Adi respondents were selected for this study.A combination of methodologies including in-depth interview,transect walks,focus group discussion,participant observation and informal interactions were combined for data ***:Local forests are classified into 10 different categories based on indicators such as topography,cultural significance,use typology,ownership rights and plant diversity *** people assign different values(economic,cultural and ecological)to different forest ***,morang followed by regpi and homegardens are perceived to be more valuable to the local needs than other forests with relative ranking of a particular forest reflecting its *** access several diverse services from these community-managed *** to men(3–35%),the role of women was assessed to be much higher(65 to 100%)in conserving forest ***-led practices,instrumental in sustainable forest management,included deliberate manipulations of micro-habitats,sustainable harvesting strategies and species *** were mostly involved in ownership and decision-making roles and in devising social norms to ensure *** celebrate a number of cultural events to sustain ***-based livelihoods are intrinsically connected to forest resource conservation and are governed by community *** of the community members gather plants,hunt wild animals and access other ecosystem se

关键词： Adi tribe Forest classification Traditional ecological knowledge Indigenous institutions Ecosystem services Conservation Livelihoods

Case-control analysis of venous thromboembolism risk in nonalcoholic steatohepatitis diagnosed by transient elastography

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World Journal of Clinical Cases 2023年第34期11卷 8126-8138页

作者： Mithil Gowda Suresh Maya Gogtay Yuvaraj singh Lekha Yadukumar ajay kumar Mishra George M Abraham Department of Internal Medicine Saint Vincent HospitalWorcesterMA 01608United States Department of Hematology and Oncology University of Nebraska Medical CenterOmahaNE 68198United States Department of Gastroenterology and Hepatology University of MassachusettsWorcesterMA 01605United States Internal Medicine The Wright Center for Graduate Medical EducationScrantonPA 18505United States Division of Cardiology Saint Vincent HospitalWorcesterMA 01608United States Internal Medicine Saint Vincent HospitalWorcesterMA 01608United States

BACKGROUND Nonalcoholic fatty liver disease(NAFLD)is the most common cause of chronic liver disease *** have shown a strong association between nonalcoholic steatohepatitis(NASH)cirrhosis and portal vein ***,there is paucity of data on the association of NASH and venous thromboembolism(VTE),with one such study predicting a 2.5-fold increased risk for VTE compared to other liver diseases in hospitalized *** mechanism is believed to be a hepatocellular injury,which causes a chronic inflammatory state leading to the unregulated activation of procoagulant *** has been no prior analysis of the degree of steatosis and fibrosis(measured using transient elastography,commonly known as FibroScan)in NASH and its association with *** To examine the association between the degree of hepatic steatosis and fibrosis,quantified by transient elastography,and the incidence of VTE in patients with *** In our case-control study,we included patients with a documented diagnosis of *** excluded patients with inherited thrombophilia,hemoglobinopathy,malignancy,alcohol use disorder,autoimmune hepatitis,and primary biliary *** collected data included age,demographics,tobacco use,recreational drug use,medical history,and vibration controlled transient elastography ***-specific data included the location,type of anticoagulant,need for hospital stay,and history of VTE *** was categorized as S0-S1(mild)and S2-S3(moderate to severe)based on the controlled attenuation parameter *** was classified based on the kilopascal score and graded as F0-F1(Metavir stage),F2,F3,and F4(cirrhosis).χ^(2) and Mann-Whitney U tests were used for the qualitative and quantitative variable analyses,***,we performed a logistic regression using VTE as the dependent *** A total of 415 patients were analyzed,and 386 met the inclusion criteria.51 and 335 patients were included

关键词： Nonalcoholic fatty liver disease Venous thromboembolism Non-alcoholic steatohepatitis Diabetes mellitus Liver fibrosis Steatosis Deep vein thrombosis Anticoagulation management

Anticancer efficacy of noble metal nanoparticles relies on reprogramming tumor-associated macrophages through redox pathways and pro-inflammatory cytokine cascades

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Cellular & Molecular Immunology 2018年第12期15卷 1088-1090页

作者： Mahuya Sengupta Ramkrishna pal Anupam Nath Biswajit Chakraborty Leichombam Mohindro singh Biswajit Das Sujit kumar Ghosh Department of Biotechnology Assam UniversitySilcharAssam 788011India Department of Chemistry Assam UniversitySilcharAssam 788011India

The use of the optoelectronic properties of noble metal nanoparticles has given a new dimension to the realm of cancer diagnosis and therapy(theranostics).The multifunctional catalytic properties and surface plasmon resonance of noble metal nanoparticles(NPs)along with their facile surface chemistry gives them an edge in the field of biology,including for immunotherapeutic *** a previous study,we reported the anticancer efficacy of silver NPs coated with murine serum albumin against fibrosarcoma in an in vivo mouse model,highlighting their role in eliciting oxystress and immune *** addition to addressing the bioavailability and toxicity parameters,our study reported that there was a significant reduction in the size,as well as a delay in the incidence of tumors with AgNP-MSA *** electron micrographs revealed AgNP-MSA uptake by sentinel immune cells associated with the tumor along with the downregulation of pro-tumorigenic inflammatory cytokines,such as TNF-α,IL-6 and IL-1β.

关键词： inflammatory diagnosis cytokine

Wooden stick penetration from the perineal region up to the thorax

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World Journal of Emergency Medicine 2015年第4期6卷 305-307页

作者： Khem pal singh anil kumar Joshi Mohit kumar Joshi Chitra Joshi Mridu singh Vikram singh V.C.S.G.Government Medical Sciences & Research Institute

BACKGROUND: Penetrating injuries of the perineum are rare but very dangerous. Since the genitourinary and colorectal organs may be injured, how to evaluate surgical management of the injury is very ***: The present report presents a case of penetrating injury of the perineum by a wooden stick when the patient fell on the upright wooden stick from a tree. The three feet long stick entered the perineal region just left lateral to the anal opening. Upon reaching the thoracic cavity, it broke and only a foot stick was left in the subcutaneous plane. These injuries are potentially serious with risk of damage to multiple organs. Exploratory laprotomy was done, and bladder injury was repaired. The entry wound and the track of stick was thoroughly washed and allowed for secondary intention ***: The post operative period was uneventful and the patient recovered ***: Meticulous evaluation and surgical management of perineal injuries are the key to prevent devastating complications.

关键词： Penetrating injury Perineal region Perineal injuries

Sitagliptin,sitagliptin and metformin,or sitagliptin and amitriptyline attenuate streptozotocin-nicotinamide induced diabetic neuropathy in rats

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The Journal of Biomedical Research 2012年第3期26卷 200-210页

作者： Ashish kumar Sharma Akash Sharma Rita kumari Kunal Kishore Divya Sharma Bharthu Parthsarthi Srinivasan Ashok Sharma Santosh kumar singh Samir Gaur Vijay singh Jatav Prashant Sharma Varnika Srivastava Sneha Joshi Megha Joshi Prashant kumar Dhakad Davender singh Kanawat Akanksha Mishra anil Sharma Dharmendra singh Ravinder pal singh Himmat singh Chawda Rambir singh Sachin kumar Raikwar Muneem kumar Kurmi Pankaj Khatri Ashutosh Agarwal Arshee Munajjam Department of Pharmacology Gyan Vihar School of PharmacySuresh Gyan Vihar UniversityJagatpuraJaipur(Rajasthan)302025India Department of Pharmacology Delhi Institute of Pharmaceutical Sciences&ResearchPushpviharNew Delhi 110017India Department of Pharmacology Kota Collage of PharmacyRIICO Industrial AreaRanpurKota(Rajasthan)Pincode 302025India

Diabetic neuropathies are a family of nerve disorders caused by diabetes. Symptoms of the disease include nerve palsy, mononeuropathy, mononeuropathy multiplex, diabetic amyotrophy, painful polyneuropathy, autonomic neu- ropathy, and thoracoabdominal neuropathy. In this study, type 2 diabetes in rats was induced with nicotinamide- streptozotocin. Drug treatment was initiated on the d 15, with the combination regimen of metformin, pioglitazone and glimipiride or metformin and sitagliptin or sitagliptin, amitriptyline and sitagliptin and led to significantly im- proved glycemic control, increased grip strength and paw jumping response on d 21, 28 and 35 （P 〈 0.001）. Signif- icant increases in blood protein levels and decreases in urinary protein levels were observed in the animals treated with the different regimens on d 21, 28 and 35 （P 〈 0.001）. Combined treatment of streptozotocin and nicotinamide caused marked degeneration of nerve cells, while administration of metformin and sitagliptin showed tissue regen- eration and no body weight gain. In conclusion, treatment with sitagliptin and sitagliptin combined with metformin or amitriptyline results in no body weight gain, but causes an increase in grip strength and pain sensitivity, exhibits neural protection, and reverses the alteration of biochemical parameters in rats with streptozotocin-nicotinamide induced type 2 diabetes.

关键词： diabetic neuropathy nicotinamide-streptozotocin metformin pioglitazone glimipiride sitagliptin amitriptyline

The growth of biopolymers and natural earthen sources as membrane/separator materials for microbial fuel cells:A comprehensive review

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Journal of Energy Chemistry 2023年第5期80卷 402-431,I0010页

作者： Gowthami palanisamy Sadhasivam Thangarasu Ranjith kumar Dharman Chandrashekar S.Patil Thakur Prithvi pal singh Negi Mahaveer D.Kurkuri Ranjith Krishna Pai Tae Hwan Oh School of Chemical Engineering Yeungnam UniversityGyeongsan 38541Republic of Korea Centre for Research in Functional Materials(CRFM) JAIN(Deemed-to-be University)Jain Global CampusBengaluru 562112KarnatakaIndia Technology Mission Division-(Energy&Water) Department of Science and Technology(DST)Ministry of Science and Technology-Govt.of IndiaNew Delhi 110016India

Microbial fuel cell(MFC)technology has emerged as an effective solution for energy insecurity and ***,identifying suitable components(particularly separators or membranes)with the required properties,such as low cost and high performance,remains challenging and restricts practical *** membranes,such as Nafion,exhibit excellent performance in ***,these membranes have high production costs,which considerably increase the overall MFC unit cell *** the numerous types,the separators or membranes developed from biopolymers and naturally occurring earthen sources have proven to be a novel and efficient concept due to their natural abundance,cost-effectiveness(approximately$20 m^(-2),$5 m^(-2),and$1 kg-1for biopolymers,ceramics,and earthensources,respectively),structural properties,proton transportation,manufacturing and modification ease,and environmental *** this review,we emphasize cost-effective renewable green materials(biopolymers,bio-derived materials,and naturally occurring soil,clay,ceramics or minerals)for MFC applications for the first *** with good thermal,mechanical,and water retention properties,sustainability,and environmental friendliness,such as cellulose and chitosan,are typically ***,the modification or introduction of various functional groups in biopolymers to enhance their functional properties and scale MFC power density is ***,separator/membrane development using various bio-sources(such as coconut shells,banana peels,chicken feathers,and tea waste ash)is ***,naturally occurring sources such as clay,montmorillonite,and soils(including red,black,rice-husk,and Kalporgan soil)for MFC were *** conclusion,the existing gap in MFC technology was filled by providing recommendations for future aspects based on the barriers in cost,environment,and characteristics.

关键词： Biomembrane Bioseparator Microbial fuel cell Energy harvesting Bioenergy Wastewater treatment

Detection of colorectal adenomas using artificial intelligence models in patients with chronic hepatitis C

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World Journal of Hepatology 2023年第1期15卷 107-115页

作者： Yuvaraj singh Maya Gogtay Anuroop Yekula Aakriti Soni ajay kumar Mishra Kartikeya Tripathi GM Abraham Department of Internal Medicine Saint Vincent HospitalWorcesterMA 01608United States Hospice and palliative Medicine University of Texas Health-San AntonioSan AntonioTX 78201United States Division of Cardiology Saint Vincent HospitalWorcesterMA 01608United States Division of Gastroenterology and Hepatology UMass Chan School-Baystate Medical CenterSpringfieldMA 01199United States Division of Infectious Disease Chief of MedicineSaint Vincent HospitalWorcesterMA 01608United States

BACKGROUND Hepatitis C virus is known for its oncogenic potential,especially in hepatocellular carcinoma and non-Hodgkin *** studies have shown that chronic hepatitis C(CHC)has an increased risk of the development of colorectal cancer(CRC).AIM To analyze this positive relationship and develop an artificial intelligence(AI)-based tool using machine learning(ML)algorithms to stratify these patient populations into risk groups for CRC/adenoma *** To develop the AI automated calculator,we applied ML to train models to predict the probability and the number of adenomas detected on *** sets were split into 70:30 ratios for training and internal *** Scikit-learn standard scaler was used to scale values of continuous *** findings were used as the gold standard and deep learning architecture was used to train six ML models for prediction.A Flask(customizable Python framework)application programming interface(API)was used to deploy the trained ML model with the highest accuracy as a web ***,Heroku was used for the deployment of the web-based API to https://*** Of 415 patients,206 had colonoscopy *** internal validation,the Bernoulli naive Bayes model predicted the probability of adenoma detection with the highest accuracy of 56%,precision of 55%,recall of 55%,and F1 measure of 54%.Support vector regressor predicted the number of adenomas with the least mean absolute error of *** Our AI-based tool can help providers stratify patients with CHC for early referral for screening *** with providing a numerical percentage,the calculator can also comment on the number of adenomatous polyps a gastroenterologist can expect,prompting a higher adenoma detection rate.

关键词： Machine learning Calculator Artificial intelligence Hepatitis C Screening

Modified Dual Segment Rectangular Dielectric Resonator Antenna Terminated in a Bio-Medium

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International Journal of Communications, Network and System Sciences 2011年第6期4卷 377-383页

作者： Ravi kumar Gangwar Surya pal singh Devendra kumar 不详

In this paper, the simulation studies of the radiation characteristics of modified dual segment rectangular dielectric resonator antenna (DSRDRA) in free space and in presence of bio-medium alongwith the absorbed power distribution in a homogenous bio-medium (muscle layer) in direct contact with the proposed antenna are reported at different WiMAX band frequencies. The specific absorption rate (SAR) distributions in muscle layer for different antenna-to-muscle layer spacings are also presented at resonant frequency of antenna in WiMAX bands. The results of return loss, input VSWR and radiation characteristics of proposed antenna in bio-medium are also compared with results in free space. The simulation study has been carried out using CST Microwave Studio software.

关键词： Modified DSRDRA SAR WiMAX band Radiation Pattern

Dosimetric Comparison of Fixed and Flexible Geometry ICRT Applicators in Patients Treated for Carcinoma Cervix

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International Journal of Medical Physics, Clinical Engineering and Radiation Oncology 2015年第1期4卷 1-6页

作者： Sukhvir singh Arti Sarin Manoj kumar Semwal ajay kumar singh Pankaj Goyal Ashok kumar Department of Radiation Oncology Army Hospital (R&R) Delhi Cantonment New Delhi India

In intracavitary radiotherapy (ICRT) for cancer cervix, applicator geometry has the potential to impact the doses to organs at risk (OARs) and the coverage of the target volume. At our centre two Varian made Fletcher-style applicator sets, namely defined (fixed) geometry and flexible geometry, are used for ICRT. In the present work, the two types of applicators were compared dosimetrically as per the recommendations of the International Commission on Radiation Units and Measurements (ICRU-38) while delivering high dose rate brachytherapy. Twenty four patients who underwent ICRT were considered for this study. Radiographic method was used for treatment planning on Abacus planning system. ICRU-38 recommended parameters were estimated and compared. Flexible geometry applicator showed 8.8% and 16% higher bladder and rectum point doses as compared to the fixed geometry one but the difference was statistically not significant. The thickness of the pear-shaped isodose volume was larger for the flexible geometry implant also indicating towards higher doses to OARs. The higher bladder and rectum point doses in the case of flexible applicator will need to be validated by a larger data set.

关键词： Carcinoma Cervix Intracavitary Radiotherapy Applicator Geometry Dosimetry