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Prognostic value of AKT isoforms in non-small cell lung adenocarcinoma

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The Journal of Biomedical Research 2023年第3期37卷 225-228页

作者： Sahil Khurana ajay pal singh Ashok Kumar Rajeev Nema All India Institute of Medical Sciences Bhopal BhopalMadhya Pradesh 462021India Department of Medicine All India Institute of Medical Sciences RishikeshRishikeshUttarakhand 249201India Department of Biochemistry All India Institute of Medical Sciences BhopalBhopalMadhya Pradesh 462021India Department of Oncology 3B Blackbio Biotech India Ltd.BhopalMadhya Pradesh 462023India

Dear Editor,Lung cancer is one of the most prevalent cancers in the world and has a high mortality *** cancer patients often have a poor prognosis,with a five-year survival rate of only about 16%.The International Agency for Research on Cancer reports that lung cancer was the main cause of cancer deaths in 2020,accounting for 1.80 million deaths.

关键词： Lung lung cancer

Spondyloptosis of C6-C7： a rare case report

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Chinese Journal of Traumatology 2010年第6期13卷 377-379页

作者： Manish Chadha ajay pal singh Arun pal singh Department of Orthopaedics Guru Teg Bahadur Hospital University College of Medical Sciences University of Delhi New Delhi 110095 India Department of Orthopaedics and Joint Replacement Indraprastha Apollo Hospital New Delhi 110095 India

A 35 years old female presented to us after falling from a height. She complained of a neck pain and a complete quadriplegia and was diagnosed as having spondyloptosis of the C6-C7. Skeletal traction was performed on her. CT scan showed fractures of the C5, C6, and C7 vertebral body. The patient underwent anterior approach partial corpectomy with anterior cervical locking plate and strut grafting from ipsilateral iliac crest. Intraoperatively it was found that the disc was completely ruptured and there was a dural tear and cerebrospinal fluid leak. Her postoperative period was complicated by cerebrospinal fluid collection and posterior instrumentation was not performed due to the poor general condition. She had no neural recovery at the last follow-up. Spondyloptosis is a severe and highly unstable injury with a three column ligamentous disruption and may be complicated, as in our case, with a dural *** of these cases is fraught with complications,and prognosis for neural recovery is dismal.

关键词： Spondylolisthesis Spine Spinal injuries

Traumatic bilateral hip dislocation with bilateral sciatic nerve palsy

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Chinese Journal of Traumatology 2010年第2期13卷 126-128页

作者： ajay pal singh Amarjit singh Sidhu Arun pal singh Department of Orthopaedics Guru Teg Bahadur Hospital University College of Medical Sciences University of Delhi Delhi 110095 India Department of Orthopaedics Rajindra Hospital Government Medical College Punjab 147001 India

Bilateral hip dislocation rarely occurs. In this paper, a case of bilateral hip dislocation associated with bilateral sciatic nerve palsy resulted from a road traffic accident is reported. Both hips were emergently reduced under general anaesthesia. Acetabular reconstruction was done bilaterally due to the unstable hips. The patient subsequently developed heterotopic ossification and avascular necrosis on the left hip and underwent total hip arthroplasty. The sciatic nerve on the right side achieved complete recovery but that on the left side only partly recovered and was augmented by tendon transfer. Such injuries are serious and one should be aware of the complications because they can resurface and so patients should be followed up for a long time. To the best of our knowledge, this kind of injury has not been reported in the English .language literature.

关键词： Hip dislocation Sciatic nerve Paralysis Accident, traffic

Effect of using borax decahydrate as nanoparticles additive in blends of spirulina biodiesel/diesel on combustion characteristics and knock intensity

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Clean Energy 2024年第3期8卷 62-78页

作者： ajay Partap singh Puneet singh Gautam Mechanical Engineering Department IIMT University Meerut250001 Uttar PradeshIndia

In this extensive investigation,the impact of borax decahydrate as a fuel additive in a diesel single-cylinder engine was rigorously *** decahydrate was introduced at concentrations of 5,15,25 and 35 g in 500 ml of biodiesel,forming five unique fuel mixtures with conventional diesel:90%diesel+10%spirulina biodiesel(SB10),SB10+1 g borax decahydrate(SB10B1),SB10+3 g borax decahydrate(SB10B3),SB10+5 g borax decahydrate(SB10B5)and SB10+7 g borax decahydrate(SB10B7).The investigation encompassed four diverse loading conditions and yielded insightful ***,at full load,SB10B3 exhibited a higher cylinder peak pressure than diesel,reaching 69.25 *** release rate profiles demonstrated superior efficiency for SB10 at 50%load,with a cumulative heat release rate of 950 J/°CA,which is lower than the 1050 J/°CA of *** intensity(KI)evaluations revealed that,although SB10 and SB10B1 exhibited higher KI than diesel at full load due to elevated peak pressure,SB10B7 showed no knocking across all loads,indicative of reduced in-cylinder *** meticulous numerical analysis emphasizes the potential of borax decahydrate as a catalyst and enhancer,providing valuable insights into the combustion dynamics of these alternative fuel blends and their viability for sustainable and efficient engine *** summary,out of all the blends,SB10B3 could be a potential diesel fuel replacement fuel for compression-ignition engines.

关键词： spirulina biodiesel borax decahydrate diesel engine combustion knock intensity HRR in-cylinder pressure

Periprosthetic subtrochanteric femoral fracture in a megaprosthesis of the knee

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Chinese Journal of Traumatology 2013年第5期16卷 314-315页

作者： Raju Vaishya ajay pal singh Abhishek Vaish Department of Orthopaedics & Joint ReplacementSurgery Indraprastha Apollo Hospitals New Delhi India Department of Orthopaedics Sancheti Institute of Or-thopaedics & Rehabilitation Pune India

We report a rare case of periprosthetic posttraumatic fracture of subtrochanteric region of femur alter a megaprosthesis of the knee, done for resistant non- union of distal femur with secondary osteoarthrosis in a 51... 详细信息

关键词： Periprosthetic fractures, Femur Femoral fractures Knee

Outcome of surgical treatment of type Ⅳ capitellum frac- tures in adults

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Chinese Journal of Traumatology 2012年第4期15卷 201-205页

作者： ajay pal singh Ish Kumar Dhammi Vipul Garg Arun pal singh Punjab Civil Medical Services-I Mukerian PunjabIn-dia Department of Orthopaedics UCMS&GTB HospitalDelhiIndia Swami Pramanand Hospital MukerianPunjabIndia

Objective： Fractures of the capitellum and trochlea constitute less than 1% of all elbow fractures and a shear fracture involving the capitellum and extending medially into most of the trochlea is rarely reported. Type Ⅳ capitellum fracture is still controversial in regard to its ra- diographic appearance, surgical approach and osteosynthesis. We report 10 cases of type Ⅳ capitellum fracture with a view to elucidating its clinical features and treatment outcome. Methods： We treated 10 patients of type Ⅳ capitellum fracture with a mean age of 32 years. A uniform surgical approach and postoperative rehabilitation were followed. Results： Nine patients presented to us after a mean of 4 days of injury and one patient was nonunion after 6 months of injury who had been treated conservatively by a bone setter. Double arc sign was absent in 6 cases. Intraopera- tively 6 capitellotrochlear fragments were devoid of soft tissue attachments. By Mayo Elbow Performance Score evaluation, 7 patients got excellent, 2 good and 1 fair results. One patient with associated elbow dislocation developed heterotopic ossification. There was no case of avascular necrosis, osteoarthrosis or fixation failures. Conclusions： Type Ⅳ capitellum fractures are rare and belong to complex articular injuries. A good functional out- come can only be achieved with open reduction and stable internal fixation followed by early mobilization. Preopera- tive radiographic assessment and computed tomography help surgeons in choosing the right surgical approach and implants. Good surgical technique and stable internal fixa- tion are the keys to early mobilization and good functional outcome.

关键词： Fractures, bone Elbow joint Fracture location, internal Bone wires

Analytical solutions fractional order partial differential equations arising in fluid dynamics

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Applied Mathematics(A Journal of Chinese Universities) 2024年第3期39卷 458-468页

作者： Sidheswar Behera Jasvinder singh pal Virdi Department of Physics Veer Surendra Sai University of TechnologyOdishaIndia

This article describes the solution procedure of the fractional Pade-Ⅱ equation and generalized Zakharov equation(GSEs)using the sine-cosine ***-Ⅱ is an important nonlinear wave equation modeling unidirectional propagation of long-wave in dispersive media and GSEs are used to model the interaction between one-dimensional high,and low-frequency *** of trigonometric and hyperbolic function solutions in fractional calculus are *** simulations of the numerical solutions are flaunted by MATLAB.

关键词： the sine-cosine method He's fractional derivative analytical solution fractional Pade-Ⅱequation fractional generalized Zakharov equation

Hopf bifurcation in a delayed prey-predator model with prey refuge involving fear effect

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International Journal of Biomathematics 2024年第5期17卷 1-32页

作者： Ankit Parwaliya Anuraj singh ajay Kumar Department of Applied Sciences ABV-Indian Institute of Information Technology and ManagementGwalior 474015India

This work investigates a prey-predator model featuring a Holling-type II functional response,in which the fear effect of predation on the prey species,as well as prey refuge,are ***,the model assumes that the growth rate of the prey population decreases as a result of the fear of ***,the detection of the predator by the prey species is subject to a delay known as the fear response delay,which is incorporated into the *** paper establishes the preliminary conditions for the solution of the delayed model,including positivity,boundedness and *** paper discusses the existence and stability of equilibrium points in the *** particular,the paper considers the discrete delay as a bifurcation parameter,demonstrating that the system undergoes Hopf bifurcation at a critical value of the delay *** direction and stability of periodic solutions are determined using central manifold and normal form ***,the global stability of the model is established at axial and positive equilibrium *** extensive numerical simulation is presented to validate the analytical findings,including the continuation of the equilibrium branch for positive equilibrium points.

关键词： Hopf bifurcation fear effect prey refuge periodic solutions time delay branch off

Neglected reverse Essex-Lopresti injury with ulnar nerve compression

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Chinese Journal of Traumatology 2011年第2期14卷 111-113页

作者： ajay pal singh Ish Kumar Dhammi Anil Kumar Jain Department of Orthopaedics UCMS & GTB Hospita Delhi 110095 India

A 45 year old woman was diagnosed as having anteromedial radial head dislocation and distal radius fracture five months after her injury on fight forearm. The radial head dislocation led to ulnar nerve compression. She had severe restriction of her elbow movements. She was treated with arthrolysis, decompression of the ulnar nerve and radial head resection. The reverse Essex Lopresti injury and radial head dislocation compressing the ulnarnerve has not been reported in English language literature to the best of our knowledge. A mechanism is proposed for the injury. In acute presentations, restoration of both the radioulnar joints should be done and neglected nature of such injury leads to suboptimal outcomes.

关键词： Radius fracture Unar nerve Elbow joint