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Journal of Tuberculosis Research 2013年第3期1卷 37-39页

作者： Vaibhav Pandey ajay narayan gangopadhyay Shiv Prasad Sharma Vijayndar Kumar Department of Paediatric Surgery Institute of Medical Sciences Banaras Hindu University Varanasi India

Abdominal tuberculosis is a significant cause of morbidity and mortality in children in developing countries. Primary involvement of appendix is very rare. Presentation is usually non specific and diagnosis is made in most cases on histopathlogical examination following appendicectomy. This to our knowledge is the first case of appendicular tuberculosis presenting primarily as spontaneous enterocutaneous fistula over front of right thigh. Barium meal follow-through was diagnostic. Appendicectomy was performed followed by anti-tubercular treatment which was curative.

关键词： Tubercular Appendicitis Abdominal Tuberculosis Enterocutaneous Fistula

Migrating Foreign Body Bronchus: An Unusual Case of Foreign Body Aspiration

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Case Reports in Clinical Medicine 2014年第7期3卷 407-409页

作者： Ram Badan Singh ajay narayan gangopadhyay Dinesh Kumar Gupta Vaibhav Pandey Department of Anaesthesia Institute of Medical Sciences Banaras Hindu University Varanasi India Department of Paediatric Surgery Institute of Medical Sciences Banaras Hindu University Varanasi India

Foreign bodies [FB] in the bronchus are important causes of morbidity and mortality in paediatric age group and pose diagnostic and therapeutic challenges. Inert and smooth foreign bodies are prone for migration from one side to other due to minimal inflammatory process and easy mobility. Herein we are reporting a case of electric bulb aspiration which migrated from right main bronchus to left main bronchus.

关键词： Foreign Body Aspiration Bulb Aspiration Migrating Foreign Body

Avoiding second donor site and the second set of neck vessels in a case of absent peroneal skin perforators

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Plastic and Aesthetic Research 2022年第1期9卷 661-666页

作者： Aditya narayan Choudhary Rajan Arora Kripa Shanker Mishra Ravi Kiran Naalla Saket Srivastava ajay Kumar Dewan Department of Reconstructive and Microvascular Surgery Rajiv Gandhi Cancer Institute and Research CentreRohiniNew Delhi 110085India Department of Surgical Oncology Rajiv Gandhi Cancer Institute and Research CentreRohiniNew Delhi 110085India

This report describes the procedure of a case in which the skin paddle of the free fibula flap derived its supply solely from a soleal musculocutaneous perforator originating from the posterior tibial *** contrast,the osteo-muscular component was supplied by the peroneal vascular *** harvested the skin paddle with its vascular supply from the posterior tibial artery separately,and the osteo-muscular fibula was harvested with its supply from peroneal *** this way,we avoided violation of the second donor site for the skin *** addition,we used the distal end of peroneal vessels to salvage our skin paddle instead of sacrificing another set of neck vessels for *** technique may also be utilised in cases where the neck vessels may not be available due to previous surgeries,radiation therapy,or decision by the surgery team to not sacrifice two sets of neck vessels for anastomosis.

关键词： Free fibula flap peroneal vessels posterior tibial vessels mandible reconstruction flaps in series

Gangrenous Amyand’s hernia in neonate: A great clinical masquerader

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Open Journal of Pediatrics 2013年第4期3卷 364-365页

作者： Vaibhav Pandey Ajar narayan gangopadhyay Dinesh Kumar Gupta Shiv Prasad Sharma Department of Paediatric Surgery Institute of Medical Sciences Banaras Hindu University Varanasi India

Amyand’s hernia [AH] is a rare condition with presence of vermiform appendix in an inguinal hernia sac [1]. It is a rare entity with very difficult preoperative diagnosis that does not affect management. We herein report a neonatal gangrenous AH masking all features of underlying bowel gangrene. In neonates, a great masquerader can mask all the features of underlying bowel gangrene and delay in diagnosis can be detrimental in context of outcome. A high index of suspicion of Amyand’s hernia with gangrene should be kept even if child presents with irreducible hernia without features of strangulation to prevent avoidable increase in morbidity and mortality.

关键词： Hernia Gangrenous Appendix Strangulation Inguinal Appendicitis

辛伐他汀对大鼠心肌缺血再灌注后细胞凋亡及线粒体融合素2表达的影响

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南通大学学报（医学版） 2016年第4期36卷 281-284页

作者： ajay Kumar Mishra 吴优 Shiv Kumar Yadav Akanand Singh Ram narayan Mandal Sailendra Jha 重庆医科大学附属第二医院心血管内科重庆404100 南通大学附属医院泌尿外科上海和睦家医院外科重庆医科大学心血管内科新疆医科大学放射科

目的:探讨辛伐他汀对大鼠心肌缺血再灌注后细胞凋亡及线粒体融合素2(Mitofusin 2,Mfn2)表达的影响。方法:选取32只Sprague-Dawley(SD)大鼠,随机分为假手术组、缺血再灌注模型组(模型组)、5 mg辛伐他汀组、10 mg辛伐他汀组,每组8只。5 m... 详细信息

目的:探讨辛伐他汀对大鼠心肌缺血再灌注后细胞凋亡及线粒体融合素2(Mitofusin 2,Mfn2)表达的影响。方法:选取32只Sprague-Dawley(SD)大鼠,随机分为假手术组、缺血再灌注模型组(模型组)、5 mg辛伐他汀组、10 mg辛伐他汀组,每组8只。5 mg辛伐他汀组、10 mg辛伐他汀组分别于术前7 d开始给予5 mg/(kg·d)、10 mg/(kg·d)的辛伐他汀灌胃,假手术组、模型组均给予等量蒸馏水灌胃。采用结扎左前降支法建立大鼠心肌缺血再灌注损伤模型。各组于造模后3 h剪取心脏组织,采用TUNEL法检测心肌细胞凋亡,Western Blot法检测p-Akt的表达,免疫组织化学法检测Mfn2的表达。结果 :与假手术组相比较,模型组心肌细胞凋亡指数、Mfn2的表达明显升高,p-Akt的表达显著降低(均P<0.05);与模型组比较,5 mg辛伐他汀组、10 mg辛伐他汀组心肌细胞凋亡指数、Mfn2的表达显著降低,p-Akt的表达显著升高(均P<0.05),并显示出明显剂量依赖性(P<0.05)。结论:辛伐他汀可有效抑制心肌缺血再灌注损伤后的心肌细胞凋亡,抑制Mfn2表达是其可能作用机制。

关键词：辛伐他汀缺血再灌注心肌细胞细胞凋亡线粒体融合素2 大鼠