检索结果-南通市图书馆

Case-control analysis of venous thromboembolism risk in nonalcoholic steatohepatitis diagnosed by transient elastography

引用

World Journal of Clinical Cases 2023年第34期11卷 8126-8138页

作者： Mithil Gowda Suresh Maya Gogtay Yuvaraj Singh Lekha Yadukumar ajay kumar Mishra George M Abraham Department of Internal Medicine Saint Vincent HospitalWorcesterMA 01608United States Department of Hematology and Oncology University of Nebraska Medical CenterOmahaNE 68198United States Department of Gastroenterology and Hepatology University of MassachusettsWorcesterMA 01605United States Internal Medicine The Wright Center for Graduate Medical EducationScrantonPA 18505United States Division of Cardiology Saint Vincent HospitalWorcesterMA 01608United States Internal Medicine Saint Vincent HospitalWorcesterMA 01608United States

BACKGROUND Nonalcoholic fatty liver disease(NAFLD)is the most common cause of chronic liver disease *** have shown a strong association between nonalcoholic steatohepatitis(NASH)cirrhosis and portal vein ***,there is paucity of data on the association of NASH and venous thromboembolism(VTE),with one such study predicting a 2.5-fold increased risk for VTE compared to other liver diseases in hospitalized *** mechanism is believed to be a hepatocellular injury,which causes a chronic inflammatory state leading to the unregulated activation of procoagulant *** has been no prior analysis of the degree of steatosis and fibrosis(measured using transient elastography,commonly known as FibroScan)in NASH and its association with *** To examine the association between the degree of hepatic steatosis and fibrosis,quantified by transient elastography,and the incidence of VTE in patients with *** In our case-control study,we included patients with a documented diagnosis of *** excluded patients with inherited thrombophilia,hemoglobinopathy,malignancy,alcohol use disorder,autoimmune hepatitis,and primary biliary *** collected data included age,demographics,tobacco use,recreational drug use,medical history,and vibration controlled transient elastography ***-specific data included the location,type of anticoagulant,need for hospital stay,and history of VTE *** was categorized as S0-S1(mild)and S2-S3(moderate to severe)based on the controlled attenuation parameter *** was classified based on the kilopascal score and graded as F0-F1(Metavir stage),F2,F3,and F4(cirrhosis).χ^(2) and Mann-Whitney U tests were used for the qualitative and quantitative variable analyses,***,we performed a logistic regression using VTE as the dependent *** A total of 415 patients were analyzed,and 386 met the inclusion criteria.51 and 335 patients were included

关键词： Nonalcoholic fatty liver disease Venous thromboembolism Non-alcoholic steatohepatitis Diabetes mellitus Liver fibrosis Steatosis Deep vein thrombosis Anticoagulation management

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Projective Tensor Products of <i>C*</i>-Algebras

引用

Advances in Pure Mathematics 2014年第5期4卷 176-188页

作者： ajay kumar Vandana Rajpal Department of Mathematics University of Delhi Delhi India

For C*-algebras A and B, the constant involved in the canonical embedding of into is shown to be . We also consider the corresponding operator space version of this embedding. Ideal structure of is obtained in case A ... 详细信息

关键词： Banach Space Projective Tensor Norm Operator Space Projective Tensor Norm

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neovascular Glaucoma: An Update on Etiopathogenesis, Diagnostics and Management

引用

Open Journal of Ophthalmology 2022年第3期12卷 242-258页

作者： Sunil kumar Sujata kumari ajay kumar Sinha Patna Medical College Patna India

Neovascular glaucoma (NVG) is a severe secondary and refractory *severe secondary conditio, that accounts for a varying prevalence between 0.01% to 5.1% of all glaucoma those studied in different regions of the world. **This is a pathological condition, which is caused by the new vessels over iris surface and followed by fibrovascular membrane formation over the trabecular meshwork, secondary to a local angiogenic stimulus. The fibrovascular membrane over trabecular meshwork obstructs the aqueous outflow at an angle of the anterior chamber. ***The obstruction in outflow of the aqueous results increase of intraocular pressure (IOP), within the eyeball. NVG results from a number of ocular and systemic conditions with retinal ischemia leading to anoxia as a mediator in over 95% of cases. Most of them are affected with proliferative diabetic retinopathy (PDR) followed by central retinal venous occlusion (CRVO), and ocular ischemic syndrome (OIS) along with other uncommon causes or all those causes that causes retinal anoxia which led to angiogenic activity in retina and iris of eye. Although NVG overall prevalence is low, but it is a dreadful condition led to blindness. The objective of this review is to provide detailed information on its basic and clinical aspects, to enable us to manage it logically. Here its etiopathogenesis, methods of early diagnosis and management are discussed. It was concluded that if NVG is detected earlier and managed systematically (both medical and surgical) along with an eye on alleviation of different aggravating factors of the retinal hypoxia, it could be a sight-saving measure to the affected person.

关键词： Neovascular Glaucoma Rubeosis Iridis Retinal Hypoxia Diabetic Retinopa-thy Central Retinal Venous Occlusion Ocular Ischemic Syndrome

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The role of cystatin A in breast cancer and its functional link with ERa

引用

Journal of Genetics and Genomics 2017年第12期44卷 593-597页

作者： Dixcy Jaba Sheeba John Mary Mohan C.Manjegowda ajay kumar Sarbajeet Dutta Anil M.Limaye Department of Biosciences and Bioengineering Indian Institute of Technology GuwahatiGuwahati 781039India

Aberrant expression of lysosomal cysteine proteinases（cathepsins）leads to abnormal proteolytic processing of extracellular matrix *** in turn promotes invasion,migration and metastasis of tumor cells（Nomura and Katunuma,2005）.Cystatins are natural inhibitors of ***,dysregulated expression of cystatins and the consequent alteration in the cathepsin：cystatin ratio are likely to play an important role in malignant progression of tumors.

关键词： breast cancer link with ERa

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Enabling intercalation-type TiNb_(24)O_(62)anode for sodiumand potassium-ion batteries via a synergetic strategy of oxygen vacancy and carbon incorporation

引用

SusMat 2023年第2期3卷 222-234页

作者： ajay Piriya Vijaya kumar Saroja Zhipeng Wang Henry R.Tinker Feng RyanWang Paul R.Shearing Yang Xu Department of Chemistry University College LondonLondonUK Materials and Catalysis Laboratory Department of Chemical EngineeringUniversity College LondonLondonUK Electrochemical Innovation Lab Department of Chemical EngineeringUniversity College LondonLondonUK

The key to develop earth-abundant energy storage technologies sodium-and potassium-ion batteries(SIBs and PIBs)is to identify low-cost electrode materials that allow fast and reversible Na^(+)/K^(+)***,we report an intercalation-type material TiNb_(24)O_(62)as a versatile anode for SIBs and PIBs,via a synergistic strategy of oxygen vacancy and carbon incorporation to enhance ion and electron *** TiNb_(24)O_(62-x)/reduced graphene oxide(rGO)composite anode delivers high reversible capacities(130 mA h g^(-1)for SIBs and 178 mA h g^(-1)for PIBs),great rate performance(54 mA h g^(-1)for SIBs and 37 mA h g^(-1)for PIBs at 1 A g^(-1)),and superior cycle stability(73.7%after 500 cycles for SIBs and 84%after 300 cycles for PIBs).The performance is among the best results of intercalation-typemetal oxide anodes for SIBs and *** better performance of TiNb_(24)O_(62-x)/rGO in SIBs than PIBs is due to the better reaction kinetics of the ***,mechanistic study confirms that the redox activity of Nb4+/5+is responsible for the reversible intercalation of Na^(+)/K^(+).Our results suggest that TiNb_(24)O_(62-x)/rGO is a promising anode for SIBs and PIBs and may stimulate further research on intercalation-type compounds as candidate anodes for large ion batteries.

关键词： anode defects intercalation potassium-ion battery sodium-ion battery sustainability

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Mass spectra and Regge trajectories of Λ_c^+,∑_c^0,Ξ_c^0 and Ω_c^0 baryons

引用

Chinese Physics C 2016年第12期40卷 10-21页

作者： Zalak Shah Kaushal Thakkar ajay kumar Rai P. C. Vinodkumar Department of Applied Physics Sardar Vallabhbhai National Institute of Technology Surat Gujarat 395007 India Department of Applied Sciences &: Humanities GIDC Degree Engineering college Abrama Navsari 396406 India Department of physics Sardar Patel University V.V. Nagar Anand 388120 India

We calculate the mass spectra of the singly charmed baryons （∧＋ c, ∑0 c,[I]0c and Ω0 c） using the hypercentral constituent quark model （hCQM）. The hyper color Coulomb plus linear potential is used to calculate the masses ofpositive （up to JP = 7＋/2 ）9 and negative （up to JP = 9-/2）parity excited states. The spin-spin, spin-orbital and tensorinteraction terms are-also incorporated for mass spectra. We have compared our results with other theoretical and lattice QCD predictions for each baryon. Moreover, the known experimental results are also reasonably close to our predicted masses. By using the radial and orbital excitation, we construct Regge trajectories for the baryons in the （n,M2） plane and find their slopes and intercepts. Other properties of these baryons, like magnetic moments, radiative transitions and radiative decay widths, are also calculated successfully.

关键词： baryons potential model Regge trajectories

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Detection of colorectal adenomas using artificial intelligence models in patients with chronic hepatitis C

引用

World Journal of Hepatology 2023年第1期15卷 107-115页

作者： Yuvaraj Singh Maya Gogtay Anuroop Yekula Aakriti Soni ajay kumar Mishra Kartikeya Tripathi GM Abraham Department of Internal Medicine Saint Vincent HospitalWorcesterMA 01608United States Hospice and Palliative Medicine University of Texas Health-San AntonioSan AntonioTX 78201United States Division of Cardiology Saint Vincent HospitalWorcesterMA 01608United States Division of Gastroenterology and Hepatology UMass Chan School-Baystate Medical CenterSpringfieldMA 01199United States Division of Infectious Disease Chief of MedicineSaint Vincent HospitalWorcesterMA 01608United States

BACKGROUND Hepatitis C virus is known for its oncogenic potential,especially in hepatocellular carcinoma and non-Hodgkin *** studies have shown that chronic hepatitis C(CHC)has an increased risk of the development of colorectal cancer(CRC).AIM To analyze this positive relationship and develop an artificial intelligence(AI)-based tool using machine learning(ML)algorithms to stratify these patient populations into risk groups for CRC/adenoma *** To develop the AI automated calculator,we applied ML to train models to predict the probability and the number of adenomas detected on *** sets were split into 70:30 ratios for training and internal *** Scikit-learn standard scaler was used to scale values of continuous *** findings were used as the gold standard and deep learning architecture was used to train six ML models for prediction.A Flask(customizable Python framework)application programming interface(API)was used to deploy the trained ML model with the highest accuracy as a web ***,Heroku was used for the deployment of the web-based API to https://*** Of 415 patients,206 had colonoscopy *** internal validation,the Bernoulli naive Bayes model predicted the probability of adenoma detection with the highest accuracy of 56%,precision of 55%,recall of 55%,and F1 measure of 54%.Support vector regressor predicted the number of adenomas with the least mean absolute error of *** Our AI-based tool can help providers stratify patients with CHC for early referral for screening *** with providing a numerical percentage,the calculator can also comment on the number of adenomatous polyps a gastroenterologist can expect,prompting a higher adenoma detection rate.

关键词： Machine learning Calculator Artificial intelligence Hepatitis C Screening

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Avoiding second donor site and the second set of neck vessels in a case of absent peroneal skin perforators

引用

Plastic and Aesthetic Research 2022年第1期9卷 661-666页

作者： Aditya Narayan Choudhary Rajan Arora Kripa Shanker Mishra Ravi Kiran Naalla Saket Srivastava ajay kumar Dewan Department of Reconstructive and Microvascular Surgery Rajiv Gandhi Cancer Institute and Research CentreRohiniNew Delhi 110085India Department of Surgical Oncology Rajiv Gandhi Cancer Institute and Research CentreRohiniNew Delhi 110085India

This report describes the procedure of a case in which the skin paddle of the free fibula flap derived its supply solely from a soleal musculocutaneous perforator originating from the posterior tibial *** contrast,the osteo-muscular component was supplied by the peroneal vascular *** harvested the skin paddle with its vascular supply from the posterior tibial artery separately,and the osteo-muscular fibula was harvested with its supply from peroneal *** this way,we avoided violation of the second donor site for the skin *** addition,we used the distal end of peroneal vessels to salvage our skin paddle instead of sacrificing another set of neck vessels for *** technique may also be utilised in cases where the neck vessels may not be available due to previous surgeries,radiation therapy,or decision by the surgery team to not sacrifice two sets of neck vessels for anastomosis.

关键词： Free fibula flap peroneal vessels posterior tibial vessels mandible reconstruction flaps in series

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Recent Advances in the Quest for Treatment and Management of Alzheimer and Other Dementia

引用

Open Journal of Medicinal Chemistry 2019年第1期9卷 1-35页

作者： Sameena E. Tanwir ajay kumar School of Science Technology and Environment Universidad Ana G. Mendez San Juan PR USA

Alzheimer’s disease (AD) is a neurodegenerative disease distinguished by progressive cognitive deterioration along with declining activities of daily living and behavioral changes. It is the commonest type of pre-senile and senile dementia. Many new therapeutic strategies have been developed in the last few years. We aimed at reviewing the evidence supporting these new therapeutic targets, including anti-amyloid and anti-Tau strategies. This review is focused on important future direction in investigation of potential therapeutic targets for AD drug discovery. Medical advances have improved treatment of many diseases but still there is a need to establish new tools for early diagnosis of AD. A thorough comprehensive understanding of the unexplored mechanism can ameliorate the diagnostic and therapeutic management of AD. There have been several disease-modifying therapeutic strategies for AD in the last few years and are presently at various phases of investigation. Few of them have shown promising results, but their safety and efficacy need to be further explored.

关键词： Alzheimer β Amyloid Tau Acetylcholinesterase Amyloid Precursor Protein Plaques Tangles Neurodegeneration

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Classification and management of community forests in Indian Eastern Himalayas:implications on ecosystem services,conservation and livelihoods

引用

Ecological Processes 2018年第1期7卷 297-311页

作者： Ranjay K.Singh Shah M.Hussain T.Riba Anshuman Singh Egul Padung Orik Rallen Y.J.Lego ajay kumar Bhardwaj College of Horticulture and Forestry Central Agricultural UniversityPasighatArunachal Pradesh 791102India ICAR-Central Soil Salinity Research Institute KarnalHaryana 132001India Doying Gumin College East SiangPasighatArunachal PradeshIndia Pasighat India

Introduction:Evidence is mounting that traditional knowledge can play a critical role in shaping the biodiversity conservation strategies and maintaining ecosystem *** study was conducted with Adi community of Arunachal Pradesh(Ar P)state in the Eastern Indian Himalayas to understand as how local systems of forest classification governs conservation tradition and influences subsistence *** Adi villages were sampled from East Siang district of Ar P.A total of 197 men and 204 women(total of 401)Adi respondents were selected for this study.A combination of methodologies including in-depth interview,transect walks,focus group discussion,participant observation and informal interactions were combined for data ***:Local forests are classified into 10 different categories based on indicators such as topography,cultural significance,use typology,ownership rights and plant diversity *** people assign different values(economic,cultural and ecological)to different forest ***,morang followed by regpi and homegardens are perceived to be more valuable to the local needs than other forests with relative ranking of a particular forest reflecting its *** access several diverse services from these community-managed *** to men(3–35%),the role of women was assessed to be much higher(65 to 100%)in conserving forest ***-led practices,instrumental in sustainable forest management,included deliberate manipulations of micro-habitats,sustainable harvesting strategies and species *** were mostly involved in ownership and decision-making roles and in devising social norms to ensure *** celebrate a number of cultural events to sustain ***-based livelihoods are intrinsically connected to forest resource conservation and are governed by community *** of the community members gather plants,hunt wild animals and access other ecosystem se

关键词： Adi tribe Forest classification Traditional ecological knowledge Indigenous institutions Ecosystem services Conservation Livelihoods

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：