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A tip-coupled, two-cantilever, non-resonant microsystem for direct measurement of liquid viscosity

Microsystems & Nanoengineering 2023年第2期9卷 23-31页

作者： Sudhanshu Tiwari ajay dangi Rudra Pratap Center for Nano Science and Engineering Indian Institute of ScienceBangaloreKarnataka 47906India Department of Biomedical Engineering Pennsylvania State UniversityUniversity ParkPA 16802USA Plaksha University MohaliPunjabIndia Present address:Oxide MEMS Lab Purdue UniversityWest LafayetteUSA

We report a non-resonant piezoelectric microelectromechanical cantilever system for the measurement of liquid *** system consists of two PiezoMEMS cantilevers in-line,with their free ends facing each *** system is immersed in the fluid under test for viscosity *** of the cantilevers is actuated using the embedded piezoelectric thin film to oscillate at a pre-selected non-resonant *** second cantilever,the passive one,starts to oscillate due to the fluid-mediated energy *** relative response of the passive cantilever is used as the metric for the fluid's kinematic *** fabricated cantilevers are tested as viscosity sensors by carrying out experiments in fluids with different *** viscometer can measure viscosity at a single frequency of choice,and hence some important considerations for frequency selection are discussed.A discussion on the energy coupling between the active and the passive cantilevers is *** novel PiezoMEMS viscometer architecture proposed in this work will overcome several challenges faced by state-of-the-art resonance MEMS viscometers,by enabling faster and direct measurement,straightforward calibration,and the possibility of shear rate-dependent viscosity measurement.

关键词： cantilever viscosity resonant

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A Transparent Ultrasound Array for Real-Time Optical,Ultrasound,and Photoacoustic Imaging

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Biomedical Engineering Frontiers 2022年第1期3卷 284-297页

作者： Haoyang Chen Sumit Agrawal Mohamed Osman Josiah Minotto Shubham Mirg Jinyun Liu ajay dangi Quyen Tran Thomas Jackson Sri-Rajasekhar Kothapalli Department of Biomedical Engineering The Pennsylvania State UniversityUniversity ParkPA 16802USA School of Electrical Engineering and Computer Science The Pennsylvania State UniversityUniversity ParkPA 16802USA Penn State Cancer Institute The Pennsylvania State UniversityHersheyPA 17033USA Graduate Program in Acoustics The Pennsylvania State UniversityUniversity ParkPA 16802USA

Objective and Impact *** imaging of ultrasound and optical contrasts can help map structural,functional,and molecular biomarkers inside living subjects with high spatial *** is a need to develop a platform to facilitate this multimodal imaging capability to improve diagnostic sensitivity and ***,combining ultrasound,photoacoustic,and optical imaging modalities is challenging because conventional ultrasound transducer arrays are optically *** a result,complex geometries are used to coalign both optical and ultrasound waves in the same field of *** elegant solution is to make the ultrasound transducer transparent to ***,we demonstrate a novel transparent ultrasound transducer(TUT)linear array fabricated using a transparent lithium niobate piezoelectric material for real-time multimodal *** TUT-array consists of 64 elements and centered at~6 MHz *** demonstrate a quad-mode ultrasound,Doppler ultrasound,photoacoustic,and fluorescence imaging in real-time using the TUT-array directly coupled to the tissue mimicking *** TUT-array successfully showed a multimodal imaging capability and has potential applications in diagnosing cancer,neurological,and vascular diseases,including image-guided endoscopy and wearable imaging.

关键词： Ultrasound specificity transparent

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Gallbladder perforation:A single-center experience in north India and a step-up approach for management

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Hepatobiliary & Pancreatic Diseases International 2022年第2期21卷 168-174页

作者： Vivek Gupta Abhijit Chandra Vishal Gupta Ravi Patel Amit dangi ajay Pai Department of Surgical Gastroenterology King George’s Medical UniversityLucknowUttar Pradesh 226003India

Background: Spontaneous gallbladder perforation(GBP) is an uncommon diagnosis. This study presented the experience of managing spontaneous GBP over nine years at a large, tertiary care university hospital in north India and investigated the outcomes and treatment strategies. Methods: A retrospective review of prospectively maintained digital database of consecutive patients was performed. All patients received medical and/or surgical treatment for spontaneous GBP in our department between January 2010 and June 2018. Results: We identifed 151 patients(81 females and 70 males) with mean age of 53 years. Most common presenting features were pain(96.7%), fever(54.3%) and jaundice(31.1%). Most common cause was gallbladder stones(84.8%) followed by common bile duct stones(30.5%), xanthogranulomatous cholecystitis(17.9%) and malignancy(11.9%). As per Niemeier classifcation, 8.6% had type 1 GBP(free perforation in peritoneal cavity), 76.2% had type 2 GBP(localized perforation) and 13.2% had type 3 GBP(cholecystoenteric fstula). About 60% of the perforations were diagnosed preoperatively. Type 1 was more common in patients with diabetes and also had the worst prognosis. Surgery was performed in 109 patients(72.2%). Seven patients(4.6%) had a postoperative morbidity of Clavien-Dindo Ⅲ or higher. There were three mortalities in patients who underwent surgery. Conclusions: High index of suspicion is required for preoperative diagnosis of GBP, especially in types 2 and 3. Laparoscopic cholecystectomy can be difficult in these patients and patients may require open or partial cholecystectomy. Early diagnosis and step-up approach for the treatment of GBP is critical.

关键词： Acute calculus cholecystitis Cholecystectomy Cholecysto-enteric fstula Niemeier classifcation

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