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Interferon-β induced in female genital epithelium by HIV-1 glycoprotein 120 via Toll-like-receptor 2 pathway acts to protect the mucosal barrier

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Cellular & Molecular Immunology 2019年第2期16卷 178-194页

作者： aisha Nazli Sara Dizzell Muhammad Atif Zahoor Victor H Ferreira Jessica Kafka Matthew William Woods Michel Ouellet Ali A Ashkar Michel J Tremblay Dawn ME Bowdish Charu Kaushic McMaster Immunology Research Centre Michael G.DeGroote Center for Learning and DiscoveryMcMaster UniversityHamiltonON L8S 4K1Canada Department of Pathology and Molecular Medicine McMaster UniversityHamiltonON L8S 4K1Canada Department of Medical Biology Laval UniversityQuebec CityQC G1V 0A6Canada

More than 40%of HIV infections occur via female reproductive tract(FRT)through heterosexual *** cells that line the female genital mucosa are the first line of defense against HIV-1 and other sexually transmitted *** sentient cells recognize and respond to external stimuli by induction of a range of carefully balanced innate immune ***,we have shown that in response to HIV-1 gp120,the genital epithelial cells(GECs)from upper reproductive tract induce an inflammatory response that may facilitate HIV-1 translocation and *** this study,we report that the endometrial and endocervical GECs simultaneously induce biologically active interferon-β(IFNβ)antiviral responses following exposure to HIV-1 that act to protect the epithelial tight junction *** innate antiviral response was directly induced by HIV-1 envelope glycoprotein gp120 and addition of gp120 neutralizing antibody inhibited IFNβ***-βwas induced by gp120 in upper GECs through Toll-like receptor 2 signaling and required presence of heparan sulfate on epithelial cell *** induction of IFNβwas dependent upon activation of transcription factor IRF3(interferon regulatory factor 3).The IFNβwas biologically active,had a protective effect on epithelial tight junction barrier and was able to inhibit HIV-1 infection in TZM-bl indicator cells and HIV-1 replication in T *** is the first report that recognition of HIV-1 by upper GECs leads to induction of innate antiviral *** could explain the overall low infectivity of HIV-1 in the FRT and could be exploited for HIV-1 prophylaxis.

关键词： antiviral response genital epithelium HIV-1 IFN-β innate immunity IRF-3 mucosal barrier TLR2

Chaotic Pigeon Inspired Optimization Technique for Clustered Wireless Sensor Networks

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Computers, Materials & Continua 2022年第12期73卷 6547-6561页

作者： Anwer Mustafa Hilal aisha Hassan Abdalla Hashim Sami Dhahbi Dalia H.Elkamchouchi Jaber S.Alzahrani Mrim M.Alnfiai Amira Sayed A.Aziz Abdelwahed Motwakel Department of Electrical and Computer Engineering International Islamic University Malaysia53100Kuala LumpurMalaysia Department of Computer and Self Development Preparatory Year DeanshipPrince Sattam bin Abdulaziz UniversityAlKharjSaudi Arabia Department of Computer Science College of Science&Art at MahayilKing Khalid UniversitySaudi Arabia Department of Information Technology College of Computer and Information SciencesPrincess Nourah Bint Abdulrahman UniversityP.O.Box 84428Riyadh11671Saudi Arabia Department of Industrial Engineering College of Engineering at AlqunfudahUmm Al-Qura UniversitySaudi Arabia Department of Information Technology College of Computers and Information TechnologyTaif UniversityTaifP.O.Box 11099Taif21944Saudi Arabia Department of Digital Media Faculty of Computers and Information TechnologyFuture University in EgyptNew Cairo11835Egypt

Wireless Sensor Networks(WSN)interlink numerous Sensor Nodes(SN)to support Internet of Things(loT)*** the data gathered from SNs can be divulged,tempered,and *** WSN data processes manage the data in a centralized format at terminal *** devices are prone to attacks and the security of systems can get *** is a distributed and decentralized technique that has the ability to handle security issues in *** security issues include transactions that may be copied and spread across numerous nodes in a peer-peer network *** breaches the mutual trust and allows data immutability which in turn permits the network to go *** some instances,few nodes die or get compromised due to heavy power *** current article develops an Energy Aware Chaotic Pigeon Inspired Optimization based Clustering scheme for Blockchain assisted WSN technique abbreviated as EACPIO-CB *** primary objective of the proposed EACPIO-CB model is to proficiently group the sensor nodes into clusters and exploit Blockchain(BC)for inter-cluster communication in the *** select ClusterHeads(CHs)and organize the clusters,the presented EACPIO-CB model designs a fitness function that involves distinct input ***,BC technology enables the communication between one CH and the other and with the Base Station(BS)in the *** authors conducted comprehensive set of simulations and the outcomes were investigated under different *** simulation results confirmed the better performance of EACPIO-CB method over recent methodologies.

关键词： Blockchain wireless sensor networks clustering energy efficiency security data transmission

Magneto-hydrodynamic flow of squeezed fluid with binary chemical reaction and activation energy

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Journal of Central South University 2019年第5期26卷 1362-1373页

作者： S.AHMAD M.FAROOQ N.A.MIR aisha ANJUM M.JAVED Department of Mathematics and Statistics Riphah International University

The present exploration is conducted to describe the motion of viscous fluid embedded in squeezed channel under the applied magnetics *** processes of heat and mass transport incorporate the temperature-dependent binary chemical reaction with modified Arrhenius theory of activation energy function which is not yet disclosed for squeezing flow *** flow,heat and mass regime are exposed to be governed via dimensionless,highly non-linear,ordinary differential equations (ODEs) under no-slip walls boundary conditions.A well-tempered analytical convergent procedure is adopted for the solutions of boundary value problem.A detailed study is accounted through graphs in the form of flow velocity field,temperature and fluid concentration distributions for various emerging parameters of enormous ***-friction,Nusselt and Sherwood numbers have been acquired and disclosed through *** results indicate that fluid temperature follows an increasing trend with dominant dimensionless reaction rate σ and activation energy parameter ***,an increment in σ and E parameters is found to decline in fluid *** current study arises numerous engineering and industrial processes including polymer industry,compression and injection shaping,lubrication system,formation of paper sheets,thin fiber,molding of plastic *** the area of chemical engineering,geothermal engineering,cooling of nuclear reacting,nuclear or chemical system,bimolecular reactions,biochemical process and electrically conducting polymeric flows can be controlled by utilizing magnetic *** by such applications,the proposed study has been developed.

关键词： squeezing flow magneto-hydrodynamics (MHD) activation energy binary chemical reaction

Solution of Stochastic Cubic and Quintic Nonlinear Diffusion Equation Using WHEP, Pickard and HPM Methods

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Open Journal of Discrete Mathematics 2011年第1期1卷 6-21页

作者： Magdy A. El-Tawil aisha F. Fareed 不详

In this paper, the cubic and quintic diffusion equation under stochastic non homogeneity is solved using Wiener- Hermite expansion and perturbation (WHEP) technique, Homotopy perturbation method (HPM) and Pickard approximation technique. The analytic solution of the linear case is obtained using Eigenfunction expansion .The Picard approximation method is used to introduce the first and second order approximate solution for the non linear case. The WHEP technique is also used to obtain approximate solution under different orders and different corrections. The Homotopy perturbation method (HPM) is also used to obtain some approximation orders for mean and variance. Using mathematica-5, the methods of solution are illustrated through figures, comparisons among different methods and some parametric studies.

关键词： Stochastic Diffusion Equations WHEP Technique HPM Method

Application of OHAM-DJ to the System of Burgers’ Equations

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American Journal of Computational Mathematics 2016年第3期6卷 212-223页

作者： Fatheah Ahmad Alhendi Bothayna Saleh Kashkari aisha Abdullah Alderremy Department of Mathematics King Abdulaziz University Jeddah Saudi Arabia Department of Mathematics King Khalid University Abha Saudi Arabia

In this paper, the system of Burgers’ equations is solved by the optimal homotopy asymptotic method with Daftardar-Jafari polynomials OHAM-DJ. Two numerical examples are illustrated the efficient of this methods for ... 详细信息

关键词： Burgers’ Equations The Optimal Homotopy Asymptotic Method Daftardar-Jafari Polynomials

Focal Point of Nursing Management of PTSD Related to COVID-19 Infection, Quarantine, and Curfew

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TMR Integrative Nursing 2021年第1期5卷 1-7页

作者： Mohammad Qutishat aisha Al Shdefat Kholoud Al Damery Lecturer Department of Community and Mental HealthCollege of NursingSultan Qaboos UniversitySultanate of Oman Lecturer Department of Maternal and Child HealthCollege of NursingSultan Qaboos UniversitySultanate of Oman

Background:Since the coronavirus outbreak(COVID-19)has been declared an emergency in public health and has drawn enormous attention worldwide,the number of infected cases and deaths *** psychological well-being of the citizens and the health team workers might be affected and lead to more anxiety and stress,such as Post Traumatic Stress ***:This paper aims to provide a holistic approach regarding nursing management of Post-Traumatic Stress Disorder concerning the COVID-19 outbreak and the consequences of lockdown,quarantine,or ***:An extensive literature searchesCumulative Index of Nursing&Allied Health Literature(CINAHL),ProQuest Nursing&Allied Health Database,Google scholar PubMed,Ovid MEDLINE,Psych articles,and Psych Info,were conducted to achieve the objective of the ***:This paper highlights that the experiences of PTSD among patients in different age groups and health conditions,as well as health team workers as a result of the COVID-19 outbreak,can be affected by several factors including health and social stigmatization,media influences,and public health *** result of this paper suggested that it is important for all nursing practices,concerning the treatment of patients with COVID-19 and its psychological symptoms,especially PTSD,to master their skills and knowledge to gather crucial information on the history of patient distress and to assess their existing levels of stress and anxiety-related the ***:The COVID-19 pandemic involves several possible causes of distress for particular people,such as experiencing a loved one's death or being terminally ill;this may lead to post-traumatic stress disorder(PTSD),which needs skilled and certified nurses to collaborate closely alongside other *** members to identify,manage and support the health of such persons effectively.

关键词： PTSD COVID-19 Nursing management Infectious disease

Trichoderma-Induced Improvement in Growth, Photosynthetic Pigments, Proline, and Glutathione Levels in Cucurbita pepo Seedlings under Salt Stress

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Phyton-International Journal of Experimental Botany 2020年第3期89卷 473-486页

作者： Mona H.Soliman Taghreed S.Alnusaire Nessreen FAbdelbaky aisha A.M.Alayafi Mirza Hasanuzzaman Mohamed M.Rowezak Mohamed El-Esawi Amr Elkelish Department of Botany and Microbiology Faculty of ScienceCairo UniversityGiza12613Egypt Biology Department College of ScienceJouf UniversitySakaka2014Saudi Arabia Biology Department Faculty of ScienceTaibah UniversityYanbu El-Bahr46429Saudi Arabia Desert Research Center Cairo11753Egypt Department of Biological Sciences Faculty of ScienceUniversity of JeddahJeddah23218Saudi Arabia Department of Agronomy Faculty of AgricultureSher-e-Bangla Agricultural UniversityDhaka1207Bangladesh Botany Department Faculty of ScienceTanta UniversityTanta31527Egypt Botany Department Faculty of ScienceSuez Canal UniversityIsmailia41522Egypt

Salt stress is one of the major abiotic stress in ***,traditional approaches are not always efficient in conferring salt *** were conducted to understand the role of Trichoderma spp.(*** and ***)in growth,chlorophyll(Chl)synthesis,and proline accumulation of *** exposed to salinity *** were three salt stress(50,100,and 150 mM NaCl)lavels and three different Trichoderma inoculation ***,***,and ***+*** stress significantly declined the growth in terms of the shoot and root lengths;however,it was improved by the inoculation of Trichoderma *** inoculated with Trichoderma exhibited increased synthesis of pigments like chl a,chl b,carotenoids,and anthocyanins under normal *** was interesting to observe that such positive effects were maintained under salt-stressed conditions,as reflected by the amelioration of the salinity-mediated decline in growth,physiology and antioxidant *** inoculation of Trichoderma *** the synthesis of proline,glutathione,proteins and increased the relative water *** addition,Trichoderma inoculation increased membrane stability and reduced the generation of hydrogen ***,Trichoderma *** be exploited either individually or in combination to enhance the growth and physiology of *** under saline conditions.

关键词： Vegetable crop antioxidant proline NaCl Cucurbita plant-microbe interaction

基于雷达检测和自动跟踪的智能交通管理系统研究

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基于雷达检测和自动跟踪的智能交通管理系统研究

作者： Algahmi aisha Hamood Ali 湖南大学

学位级别：硕士

随着智能交通管理系统的部署,交通管理系统能够在没有强人工参与条件下自动运行。调查发现,已部署智能交通系统国家的高速公路交通事故率大大降低,而我国(也门)是交通事故的高发地区,因为我们还依赖于传统交通系统来监测道路状况。过去... 详细信息

随着智能交通管理系统的部署,交通管理系统能够在没有强人工参与条件下自动运行。调查发现,已部署智能交通系统国家的高速公路交通事故率大大降低,而我国(也门)是交通事故的高发地区,因为我们还依赖于传统交通系统来监测道路状况。过去几年,也门是公路事故发生率最高的国家之一,而在采用智能技术系统监测道路交通的国家,交通事故的比例大大降低。因此,在类似也门这样的国家,应用智能技术的目标是创建一个为交通管理和警察服务的双重系统,通过减少人为误差来减少交通事故和人员伤亡,通过系统中的嵌入摄像头来实现对通缉犯的自动追踪。为了解决这个问题以及尽可能的减少负面影响,作者试图通过设计一个基于雷达的智能系统来控制车辆的移动并自动识别违规行为。雷达的功能用来检监测车辆的速度,如果某个车辆的速度超过限制速度,雷达将通过系统向摄像头发送命令拍摄该车辆的图像,图像处理系统会识别并提取车牌号码,车牌类型等信息,然后将提取的数据发送到与系统链接的交通数据库与提取到的数据进行比对得到车主的信息(如手机号码)。然后系统依靠数据库中的手机号码,通过短信将违规信息发送给车主。在该系统中,试图构造有助于提升也门共和国安全部管理能力的解决方案,会尽力配合主管部门并向其推荐该系统。该系统可以用于跟踪违法者和通缉犯。系统通过将他们的图像链接接到系统的特定数据库中来识别违法者,当某个嫌疑人经过分布在系统的任何一个监控探头前,探头会进行抓拍并与数据库进行比较,最后将监控探头的位置坐标(包括该人的照片)报告给主管当局。本项目所使用的雷达系统的任务是检测高速公路上车辆的速度,通过部署这个系统,可以显著降低每个国家伤亡交通事故的发生率,我国(也门)是发生道路交通事故最多的国家之一。在本研究中我们对这个项目进行模拟仿真。该项目包含一个雷达系统,该系统能够有效地减少超速带来的一系列危险问题并尽可能消除他们,同时实现一个永久在线(24小时)的智能系统,可以在无人工干预的情况下高效持续地跟踪和监控违法者并发出通缉。智能交通系统中的雷达被安装在道路的两侧,通过发射特定频率的雷达波到其前方的车辆来执行任务。电磁波与特定的目标发生碰撞,并以回波的形式返回至雷达。这样雷达可以计算检测车辆的速度并在雷达屏幕上显示出来。然后将该速度与最大限制速度进行比较。如果检测到车辆速度超过允许速度,则将命令发送至与系统连接的摄像头,以拍摄车辆(车牌)并处理照片。提取照片中的信息,我们将在图像处理系统的后续步骤中应用到。雷达探测车通过发射天线发射电磁波信号,信号与目标(汽车)发生碰撞后被反射回致接收雷达的天线,测速车再将信号转换为与此频率(多普特频率)相对应的速度来实现测速的过程。信号的到达频率高于信号发射频率的现象被称为多普勒漂移或多普勒效应。雷达通过计算信号传播的距离以及到达目标和反射回雷达所需的时间,得到被检测车辆的速度。然后将该速度值与最大限速(100公里)进行比较,判断出被检测车辆是正常速度还是超速。我们设计的系统检测过程如下:首先,通过雷达检测目标车辆的速度,如果有超速的情况,则像摄像机发出捕获车辆图像的命令。然后进入下一部分,摄像机执行命令拍摄图像,通过图像处理步骤提取车牌号并将提取到的所需信息记录到违规档案中。最后一个步骤是自动存储,将所有从图像处理部分提取的信息(速度和多普勒频率),例如,车牌和车的类型自动存储到交通数据库的表格中,该步骤同时负责从数据库中获取违规车主的电话号码,并自动发送信息给车辆所有者,当速度超过极限速度,通过短信发送违规信息给司机。真人脸识别系统包含许多连接部分。第一部分是雷达设备,第二部分应用Arduino作为可编程微处理器(接口),它允许我们用Arduino程序语言编写应用程序,因此当Arduino编写的应用程序发现超速之后,向摄像机发出命令,如果速度过快,它就输出到第四部分(其中包括速度和多普勒频率),第三部分是一个摄像机连接到另一个微处理器(第四部分),以便进行拍摄图像的图像处理,第四部分连接到数据库(这个上面已经提到),第五部分和最后部分是一个相机连接到了另一个微处理器(第四部分),这部分是为了进行定位追踪和人脸面部识别,并且这部分还与特殊数据库连接,该特殊数据库包含了导入的图像,这些部分的实现都是通过连接GPS定位器来识别位置,并通知当局目标的位置坐标。真实系统的所有部分都需要与相互联通的网络连接起来,完成相应的任务。图像处理系统的实现过程是:当雷达探测到车辆超过允许速度时,监控探头就会接收到一个拍摄照片的电磁波信号,并立即拍摄雷达前面车辆的照片。系统对该照片进行处理,识别出金属车牌并提取所需的信息,系统识别出车主后将违章信息通过短信发送到对应车主的手机号码。该系统的另一功能是人脸识别,在人经过安装有监控摄像头的街道时,将图像实时与安全部门的通缉人员数据库进行比较。对采集的

关键词：智能交通系统雷达 C# SQL Matlab

Electron-Positron Pair Production in Electro-Magnetic Field

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Journal of Applied Mathematics and Physics 2022年第2期10卷 237-244页

作者： Sadah A. Alkhateeb aisha Abdu Alshaery Rawan Ali Aldosary Mathematics Department Faculty of Science University of Jeddah Jeddah Saudi Arabia

At very high energies, pair production formation (γ + N → e+e-) exhibits a variety of intriguing properties. Analytically and quantitatively, the formation of Electron-Positron pairs in the Electro-Magnetic field of light nuclei has been calculated. In Ultra-Relativistic (UR) areas of incident photon energy, applying the resulting formulas to the energy distribution of the (e-, e+) operation. When we compare the results, we can observe that the Magnetic field of the target nucleus is more efficacious than the Electric field of the nucleus in the (e-, e+) operation. Furthermore, we can show that in Pair Production operation, the Differential Cross Section (DCS) owing to the target nucleus’s Electric Quadrupole (EQ) and Magnetic Octupole (MO) are bigger than the Differential Cross Section (DCS) attributable to the target nucleus’s Electric Charge (EC) distribution and Magnetic Dipole (MD).

关键词： Pair Production Positron Differential Cross Section The Bethe-Hitler Equation