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肝硬化血小板减少症的临床管理

中华肝脏病杂志 2024年第6期32卷 489-492页

作者：李剑萍谭颖孙航林淦秋陈彬彬吴跃谢志伟王亚萍陆霭琪关玉娟广州医科大学附属市八医院肝病中心广州510440

血小板减少症是肝硬化的常见并发症之一,它可引起肝硬化患者的出血风险增加,并与侵入性操作后的出血密切相关,因此如何应对血小板减少症对改善肝硬化患者的预后至关重要。现就肝硬化并发血小板减少症的几种主要机制以及相应的临床管理... 详细信息

血小板减少症是肝硬化的常见并发症之一,它可引起肝硬化患者的出血风险增加,并与侵入性操作后的出血密切相关,因此如何应对血小板减少症对改善肝硬化患者的预后至关重要。现就肝硬化并发血小板减少症的几种主要机制以及相应的临床管理策略进行综述。

关键词：肝硬化血小板减少症干预策略

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北京地铁自动售检票系统技术改造的探索

铁路通信信号工程技术 2021年第5期18卷 77-82,94页

作者：陈楠李郁李爱琦孟凡琛张征张东辉北京市基础设施投资有限公司北京100101 北京全路通信信号研究设计院集团有限公司北京100070 北京轨道交通路网管理有限公司北京100101

北京地铁网络化运营格局形成,并进入更新改造阶段,提出对全网自动售检票系统进行软件升级、硬件改造、统一全网AFC系统标准、对业务规则体系进行完善,使全网AFC系统具备灵活实施业务规则功能,并为后续自动售检票系统全网改造提供参考。

关键词：自动售检票网络化标准化

Transient positive antimitochondrial M2 in sera of patients with connective tissue diseases after intravenous immunoglobulin infusions

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Rheumatology & Autoimmunity 2022年第4期2卷 230-236页

作者： lijuan Yang Xiuning Wei Qianhua li Honggui li Zhiming Ouyang aiqi Zeng Donghui Zheng lie Dai Yingqian Mo Department of Rheumatology Sun Yat‐Sen Memorial HospitalSun Yat‐Sen UniversityGuangzhouChina

Background:Although antinuclear antibodies(ANAs),anti‐SSA and anti‐Ro52,are present in immunoglobulin preparations,it is unknown whether intravenous immunoglobulin(IVIG)therapy influences the testing of serum autoantibodies in patients with connective tissue diseases(CTDs).The present study aimed to investigate the dynamic change over time of serum ANA‐related autoantibodies in patients with CTDs receiving IVIG ***:Serum ANA‐related autoantibodies were monitored in two patients with CTD before IVIG therapy and at different times after *** autoantibodies were tested in different batches of immunoglobulin preparations from seven pharmaceutical ***:One patient developed a new ANA pattern(cytoplasmic dense fine speckled pattern,AC‐19)just after IVIG *** patients developed de novo positivity for AMA‐M2 and anti‐SSA,but returned negative 1 month after IVIG *** residual liquid in patients'immunoglobulin preparations showed positive ANAs with a high titer of AC‐19(1:640),a low titer of the nuclear fine speckled pattern(AC‐4,1:80),positive AMA‐M2,and positive anti‐***‐related autoantibodies were tested in 16 batches of immunoglobulin preparations and all had positive ANAs with two patterns:AC‐19(1:640 or 1:320)and AC‐4(1:80).AMA‐M2 and anti‐SSA were positive in 100%of the ***:Our study highlights high‐titer AMA‐M2 autoantibodies in immunoglobulin preparations and suggests their transient transfer into a patient's circulation via IVIG *** avoid incorrect clinical decisions based on postinfusion antibody titers,our data recommend retesting 1–2 months after high‐dose IVIG immunomodulatory treatment.

关键词： antimitochondrial M2 antinuclear antibodies connective tissue disease intravenous immunoglobulins

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耐热酵母与酿酒酵母原生质体融合的研究

生物工程学报 1990年第3期6卷 224-229页

作者：方霭祺李绍兰陈有为李萍云南省微生物研究所

酿酒酵母(Saccharomyces cerevisiae)396是利用甘蔗糖蜜生产酒精的生产菌株,假丝酵母(Candtda sp.)C_6是我们从云南温泉底泥中筛选到的一株能在45℃生长良好的耐热酵母,我们应用原生质体融合技术进行了两菌株属间融合的研究。通过亚硝基... 详细信息

酿酒酵母(Saccharomyces cerevisiae)396是利用甘蔗糖蜜生产酒精的生产菌株,假丝酵母(Candtda sp.)C_6是我们从云南温泉底泥中筛选到的一株能在45℃生长良好的耐热酵母,我们应用原生质体融合技术进行了两菌株属间融合的研究。通过亚硝基胍(NTG)诱变得到的营养缺陷型菌株396(arg^-)和C_6(lys^-),其融合频率为0.91×10^(-5)。从检出的融合子中挑选6株进行考核、其细胞体积平均为亲株的1.3倍,DNA含量平均为亲株的1.6倍,培养特征、形态、大小和生理生化特征表现不一,特别是糖类的同化试验。除F_2、F_(14)外,其他4株可以排除异核体形成的可能性。比较了在28℃,40℃和45℃培养条件下出发亲株396、C_6、直接亲株396(arg^-)C_6(lys^-)和融合子F_1、F_7、F__(12)、F_(13)的生长曲线、基质利用率和乙醇产率等,得到一株在40℃培养条件下糖的利用率为94.3%、乙醇产量为59.

关键词：酵母原生质体融合

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频谱分析原理及频谱分析仪使用技巧

中国标准化 2017年第1X期 34-,40页

作者：李艾祺李国强天津市电子仪表实验所

本文则通过阐释频谱分析的原理以及频谱分析仪的使用,旨在让更多的人了解频谱分析,学会使用频谱分析仪,充分发挥科技的伟大能量.

关键词：频谱分析原理分析仪使用技巧

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频谱分析仪在电磁干扰标准测量中的应用

中国标准化 2017年第1X期 203-,205页

作者：李国强李艾祺天津市电子仪表实验所

本文中将频谱分析仪作为分析电磁干扰数据的主要仪器,使得各项数据测量的更加准确,以此提高电磁干扰测量的效率.

关键词：频谱分析仪信号分析电磁干扰校准放射测试

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基于感性意象的并条机造型设计

纺织学报 2022年第4期43卷 160-166页

作者：段金娟宣艾祺袁博李娜娜天津工业大学机械工程学院天津300387 拉夫堡大学航空与车辆工程学院莱斯特郡LE113TU 天津工业大学纺织科学与工程学院天津300387

为更准确地满足用户对纺织机械造型的感性需求,提升造型设计效率,基于感性工学和数量化理论I(QTI),以并条机为例展开设计与实验研究。首先,筛选、确定并条机代表性样本和典型感性意象词对,通过实验获取用户感性评价数据;其次,基于QTI建... 详细信息

为更准确地满足用户对纺织机械造型的感性需求,提升造型设计效率,基于感性工学和数量化理论I(QTI),以并条机为例展开设计与实验研究。首先,筛选、确定并条机代表性样本和典型感性意象词对,通过实验获取用户感性评价数据;其次,基于QTI建立并条机感性意象与造型设计要素之间的关联模型,以“繁琐-简约”语义维度为例,求解模型得到造型设计推荐策略;最后,通过设计实践与用户评价,验证关联模型的准确性和可靠性。结果表明:基于感性工学和QTI的并条机关联模型具有较好的预测精度和可靠性,可为设计师提供较为准确、具体的设计策略推荐,提升设计效率,提高用户满意度。

关键词：感性意象数量化理论I 并条机纺织机械造型设计

Relationship between Chief Executive Officer characteristics and corporate environmental information disclosure in Thailand

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Frontiers of Engineering Management 2019年第4期6卷 564-574页

作者： Dayuan li aiqi liN Lu ZHANG Collaborative Innovation Center of Resource-Conserving&Environment-Friendly Society and Ecological Civilization School of BusinessCentral South UniversityChangsha 410083China

This study focuses on the influence of Chief Executive Officer(CEO)characteristics on environmental information disclosure(EID)in the annual reports of companies listed on the Stock Exchange of Thailand.A regression analysis method is used to explore the relationship between CEO characteristics and corporate environmental ***-intensive companies are taken as the samples in this *** show that financial expertise,educational level,and tenure of CEOs are positively correlated with corporate *** contrast,age or gender of CEOs is insignificantly related to EID.

关键词： CEO characteristics environmental information disclosure Thailand

The study on the safety and efficacy of amnion graft for preventing the recurrence of moderate to severe intrauterine adhesions

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Genes & Diseases 2020年第2期7卷 266-271页

作者： Changjiang li aiqi Cai Congcong Sun Benyuan Wu Xinpei Chen Yanhua Mao Yingfeng Zhang Yating Gou Jie Yu Yuhan Wang Huanhuan Yu Jia Wang Department of Obstetrics and Gynecology University-Town Hospital of Chongqing Medical UniversityChongqingChina

Transcervical resection of adhesion(TCRA)is the standard treatment for the intrauterine adhesions,but the recurrence of adhesions is a tough problem for the *** addition,the therapeutic strategy after TCRA about prevention of recurrence remains controversial especially for the patients with moderate to severe intrauterine adhesions(IUAs).Hence,we designed this study to explore the safety and efficacy of fresh amnion grafts for preventing the recurrence after TCRA for patients with moderate to severe *** hundred patients with moderate to severe IUAs who presented with a history of hypomenorrhea,amenorrhea and infertility were included in the study from January 2015 to December *** were divided into amnion group(52 patients)and chitosan group(48 patients).Fresh amnion grafts or intrauterine injections of chitosan were administered after *** ultrasonography(TVUS)and hysteroscopy were performed at the first and third month after the *** surgical procedures for all patients were completed successfully without relevant *** amnion group,8 patients exhibited relapse in the first month and 2 patients in three months after surgery;in chitosan group,23 women exhibited relapse in the first month and 18 patients in three months after *** analysis revealed that the recurrence rate of adhesion in amnion group was significantly lower than those of chitosan group in the first and three months after surgery(P1=0.000,P2=0.000).After TCRA,fresh amnion graft plays a significant role in preventing further adhesions than injections of chitosan.

关键词： Amnion graft Asherman’s syndrome Intrauterine adhesions Recurrence of adhesion Transcervical resection of adhesion