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Simple hematological predictors of AF recurrence in patients undergoing atrial fibrillation ablation

Journal of Geriatric Cardiology 2019年第9期16卷 671-675页

作者： George Bazoukis Konstantinos P Letsas Konstantinos Vlachos Athanasios Saplaouras Dimitrios Asvestas Konstantinos Tyrovolas aikaterini rokiza Eirini Pagkalidou Gary Tse Stavros Stavrakis Antonios Sideris Michael Efremidis Department of Cardiology Electrophysiology Laboratory Evangelismos General Hospital of Athens Athens Greece Department of Hygiene and Epidemiology School of Medicine Aristotle University of Thessaloniki Thessaloniki Greece Department of Medicine and Therapeutics Faculty of Medicine Chinese University of Hong Kong Hong Kong China Li Ka Shing Institute of Health Sciences Faculty of Medicine Chinese University of Hong Kong Hong Kong SAR China Department of Medicine Cardiovascular Section Heart Rhythm Institute University of Oklahoma Health Sciences Center Oklahoma City Oklahoma USA

Backgound Red cell distribution width(RDW) and neutrophil-to-lymphocyte ratio(NLR) are simple hematologic indices that have been used to predict adverse outcomes in different clinical settings. The aim of our study is to determine whether RDW and NLR can predict atrial fibrillation(AF) recurrence in patients undergoing AF ablation. Methods Consecutive patients, without known hematological disorders, who underwent AF catheter ablation between January 2014 and April 2017 were enrolled into this study. Blood samples were taken one day before and five hours after the ablation procedure. Results A total of 346 patients(224 males(65%), mean age: 59 ± 11 years old) were included. After a mean follow up of 26.2 ± 12.1 months, 80(23.1%) patients experienced late AF recurrence(defined as any recurrence after the blanking period of three months), while 97(28%) patients experienced early AF recurrence during the blanking period. Univariate analysis showed that early arrhythmia recurrence, type of AF and NLR after the procedure were significantly associated with late AF recurrence, while early arrhythmia recurrence and NLR remained significant in multivariate analysis. RDW was not associated with late AF recurrence. None of the parameters above predicted early arrhythmia recurrence. Conclusions Simple and inexpensive hematological indices such as NLR should be evaluated for their ability to predict AF recurrence in patients undergoing catheter ablation in larger prospective studies.

关键词： Atrial fibrillation Neutrophils Radiofrequency ablation

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Photofermentative hydrogen production by immobilized Rhodopseudomonas sp. S16-VOGS3 cells in photobioreactors

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Energy Reviews 2024年第1期3卷 39-48页

作者： Isabela C.Moia aikaterini Kanaropoulou Demetrios F.Ghanotakis Pietro Carlozzi Eleftherios Touloupakis Research Institute on Terrestrial Ecosystems National Research CouncilVia Madonna del Piano 1050019Sesto FiorentinoFIItaly Department of Chemistry University of CreteVoutes Campus70013 HeraklionGreece

One of the most important solutions to overcome energy and environmental problems and to replace the fossil fuel-based economy could be the use of photosynthetic *** use of photosynthetic microorganisms is a potential alternative to energy generation from fossil fuels because they efficiently produce hydrogen(H_(2)).Immobilization of photosynthetic microorganisms is used for many biotechnological applications such as H_(2) *** method appears attractive because it restricts cell movement in an entrapped *** of Rhodopseudomonas sp.S16-VOGS3 cells is a promising way to improve H_(2) *** this work,the ability of immobilized Rhodopseudomonas sp.S16-VOGS3 cells to produce H_(2) was investigated in two types of *** PBRs used in this work were a cylindrical one with 0.2 L working volume(C-PBR)and a flat Roux type with 0.6 L working volume(FRT-PBR).The calcium alginate beads prepared were resistant to culture mixing and showed little leakage of cells,and the immobilized cells continued the photofermentation process in both *** immobilized cells in the C-PBR produced 936.8 mL of H_(2) with an average H_(2) production rate of 2.99 mL/*** average productivity was 126.4μL(H_(2))/mg(cells)/h or 14.96 mL(H_(2))/L(culture)/h,and the light conversion efficiency was 2.37%.The immobilized cells in the FRT-PBR produced a total of 662.2 mL of H_(2) with an average H_(2) production rate of 1.55 mL/*** average productivity was 31.1μL(H_(2))/mg(cells)/h or 2.58 mL(H_(2))/L(culture)/h,and the light conversion efficiency was 0.52%.The more uniform and therefore more efficient degree of bacterial cell mixing achieved in the C-PBR with cylindrical configuration played an important role compared to the *** the FRT-PBR,the beads were aggregated at the bottom,which limited light penetration and resulted in low H_(2) production efficiency.

关键词： Photobioreactor Rhodopseudomonas sp.S16-VOGS3 Photofermentation Hydrogen production Calcium alginate

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Investigation on modeling parameters of concrete beams reinforced with basalt FRP bars

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Frontiers of Structural and Civil Engineering 2019年第6期13卷 1520-1530页

作者： Jordan CARTER aikaterini S.GENIKOMSOU Civil Engineering Department Queen s UniversityKingstonON K7N 3N6Canada

Fiber-reinforced polymer(FRP)bars are widely used as internal reinforcement replacing the conventional steel bars to prevent from *** the different types of FRP bars,basalt FRP(BFRP)bars have been used in different structural applications and,herein,three already tested concrete beams reinforced with BFRP bars are analyzed using three-dimensional(3-D)finite element analysis(FEA).The beams were tested in four-point *** the FEA the behavior of concrete is simulated using the^Concrete-Damaged Plasticity^^model offered in ABAQUS *** research presented here presents a calibrated model for nonlinear FEA of BFRP concrete beams to predict their response considering both the accuracy and the computational *** calibration process showed that the concrete model should be regularized using a mesh-dependent characteristic length and material-dependent post-yield fracture and crushing energies to provide accurate mesh-size independent *** results were compared to the test results with regard to failure load and crack *** the test results and the numerical results were compared to the design predictions of ACI 440.1R-15 and CSA S806-12,where CSA S806-12 seems to overestimate the shear strength for two beams.

关键词： basalt Fiber-reinforced polymer bars reinforced concrete beams finite element analysis damaged plasticity model design codes

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Spatial analysis and evaluation of a coal deposit by coupling AHP & GIS techniques

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International Journal of Mining Science and Technology 2019年第6期29卷 943-953页

作者： Nikolaos Paraskevis Christos Roumpos Nikolaos Stathopoulos aikaterini Adam Department of Mining Engineering Public Power Corporation of GreeceAthens 10432Greece School of Mining and Metallurgical Engineering National Technical University of AthensAthens 15780Greece

Nowadays,the evaluation of coal deposits becomes crucial,due to many uncontrollable factors,which affect the energy sector.A comparative evaluation of coal deposits is essential for their hierarchical classification regarding their sustainable exploitation,when compared to other coal deposits or competitive fuels,which may be used as alternative solutions for electricity *** this paper,a method for spatial analysis and evaluation of a lignite deposit is proposed,by creating four spatial key indicators via GIS analysis,which are then aggregated by applying a weighted linear *** analytical hierarchy process is applied to estimate the relative weights of the indicators,in order to perform a weighted cartographic *** the synthesis of the indicators,an overall,total spatial quality indicator is *** weighted analysis was shown to be more effective compared to the unweighted one,because it can provide more reliable results regarding the exploitation of the examined lignite *** implementation of GIS-based analytical hierarchy process in spatial analysis and evaluation of lignite deposits,in terms of sustainable exploitation,demonstrates that this method can be extensively applied for evaluating the economic potential of mineral deposits.

关键词： Lignite/coal deposit Spatial analysis Evaluation Cartographic overlay Analytical hierarchy process Geographic information systems Weighted linear combination(WLC) Weighted spatial quality indicator(WSQI)

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Fragility assessment of wood sheathing panels and roof-to-wall connections subjected to wind loading

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Frontiers of Structural and Civil Engineering 2021年第4期15卷 867-876页

作者： Amira Gill aikaterini S.GENIKOMSOU Georgios P.BALOMENOS Department of Civil Engineering Queen’s UniversityKingstonK7L 3N9Canada Department of Civil Engineering McMaster UniversityHamiltonL8S 4L7Canada

The performance of the wood-frame buildings after tornadoes has shown that the majority of the wind damage resulted from building envelope failure most typically due to the loss of the *** assess the performance and the reliability of low-rise wood-frame residential buildings with a focus on the roofs,fragility analysis can be used to estimate the probability of failure of a roof when constructed with specified nails and sheathing ***,this paper examines the fragility of specific types of nails,roof-to-wall(RW)connection details,and sheathing sizes based on the damaged roofs that were previously assessed in the Dunrobin area in Ottawa(Ontario)that was hit with an Enhanced Fujita(EF3)tornado on September 21,*** presented fragility analysis considers four scenarios,including different sheathing and nail *** loads,wind loads,and resistance on the sheathing panels were compiled and analyzed to determine the failure of the examined *** eight fragility models suggest that the safest roof sheathing(RS)is the 1.22 m×1.22 m sheathing panel with 8 d nails,and the safest RW connections is achieved by using H2.5 hurricane clips.

关键词： tornadoes wind loads low-rise buildings fragility analysis risk assessment structural failures

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Interplay between metabolic dysfunction-associated fatty liver disease and chronic kidney disease:Epidemiology,pathophysiologic mechanisms,and treatment considerations

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World Journal of Gastroenterology 2022年第39期28卷 5691-5706页

作者： Panagiotis Theofilis aikaterini Vordoni Rigas G Kalaitzidis Center for Nephrology“G.Papadakis ”General Hospital of Nikaia-Piraeus“Agios Panteleimon”Nikaia 18454Greece

The recently proposed nomenclature change from non-alcoholic fatty liver disease to metabolic dysfunction-associated fatty liver disease(MAFLD)has resulted in the reappraisal of epidemiological trends and associations with other chronic *** this context,MAFLD appears to be tightly linked to incident chronic kidney disease(CKD).This association may be attributed to multiple shared risk factors including type 2 diabetes mellitus,arterial hypertension,obesity,dyslipidemia,and insulin ***,similarities in their molecular pathophysiologic mechanisms can be detected,since inflammation,oxidative stress,fibrosis,and gut dysbiosis are highly prevalent in these pathologic *** the same time,lines of evidence suggest a genetic predisposition to MAFLD due to gene polymorphisms,such as the PNPLA3 rs738409 G allele polymorphism,which may also propagate renal *** their management,available treatment considerations for obesity(bariatric surgery)and novel antidiabetic agents(glucagon-like peptide 1 receptor agonists,sodiumglucose co-transporter 2 inhibitors)appear beneficial in preclinical and clinical studies of MAFLD and CKD ***,alternative approaches such as melatonin supplementation,farnesoid X receptor agonists,and gut microbiota modulation may represent attractive options in the *** a look to the future,additional adequately sized studies are required,focusing on preventing renal complications in patients with MAFLD and the appropriate management of individuals with concomitant MAFLD and CKD.

关键词： Metabolic dysfunction-associated fatty liver disease Chronic kidney disease Hepatic steatosis inflammation Type 2 diabetes mellitus Obesity

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Compressive and cyclic flexural response of double-hooked-end steel fiber reinforced concrete

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Frontiers of Structural and Civil Engineering 2022年第9期16卷 1104-1126页

作者： Demewoz W.MENNA aikaterini S.GENIKOMSOU Mark F.GREEN Department of Civil Engineering Queen’s UniversityKingstonON K7L 3N6Canada

Recent developments on high-performance double-hooked-end steel fibers have enhanced the wide applications of steel fiber reinforced concrete(SFRC).This study presents the compressive properties and the cyclic flexural performance of the SFRC that were experimentally *** different double-hooked-end steel fibers at 0.25%,0.5%,0.75%,and 1%volume fractions were *** fiber types had similar length to diameter ratios,while the first two fiber types had similar anchorage mechanisms(4D)and tensile strength and the third type had different anchorage mechanism(5D)and a higher tensile *** increased volumetric ratio of the fibers increased the post-peak compressive strain(ductility),the tensile strength,and the cyclic flexural strength and cumulative energy dissipation characteristics of the *** the 4D fibers,the mixtures with the larger steel fibers showed higher flexural strength and more energy dissipation compared to the SFRCs with smaller size *** 1%steel fiber dosage,4D and 5D specimens showed similar cyclic flexural ***,a 3D finite element model that can predict the monotonic and cyclic flexural responses of the double-hooked-end SFRC was *** calibration process considered the results obtained from the inverse analysis to determine the tensile behavior of the SFRC.

关键词： steel fiber reinforced concrete fiber geometry cyclic loading energy dissipation finite element modeling inverse analysis

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Growth responses of seedlings produced by parent seeds from specifi caltitudes

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Journal of Forestry Research 2020年第6期31卷 2121-2127页

作者： Valasia Iakovoglou Ioannis Takos Georgia Pantazi aikaterini Pipsou Maria Neofotistou Department of Forestry and Natural Environment Management Eastern Macedonia and Thrace Institute of Technology(EMaTTECH)66100 DramaGreece

Restoration activities in semi-arid Mediterranean areas like Greece face many obstacles,such as summer droughts that are becoming more intense with climate change,that pose limitations to transplanting *** for restoration must be of high quality;a vigorous root system is critical to enable seedlings to tolerate adverse *** we investigated the eff ects of altitude and source parent for seeds on the growth of subsequent seedlings to determine the best seed sources for obtaining highest-quality,most-tolerant seedlings for restoration eff *** of Quercus coccifera *** collected on an altitudinal gradient of 50 m(200,250 and 300 m a.s.l.)and from specifi c parents at each *** seedlings were grown for 3 months in a greenhouse with controlled *** results indicated a strong altitudinal and parental seed eff ect on seedling *** altitude decreased,biomass of the seedlings increased,and they developed more vigorous roots and more photosynthetic leaf ***,altitude and parent are critical factors to consider when producing seed-derived *** collecting seeds from a specifi c altitude and parent,more vigorous and stresstolerant seedlings can be obtained to enhance transplanting success.

关键词： Climate change Conservation Nursery practices Regeneration Seedling physiology

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Type 2 diabetes and quality of life

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World Journal of Diabetes 2017年第4期8卷 120-129页

作者： aikaterini Trikkalinou Athanasia K Papazafiropoulou Andreas Melidonis Department of Internal Medicine and Diabetes Center Tzaneio General Hospital of Piraeus18536 PiraeusGreece

It is true that a primary goal of diabetes early diagnosis and treatment is quality of life(QoL). The term QoL is still confusing but it is agreed that it composes of four components:The physical component, mental, cogitative component, psychological and social component. Many articles have been written addressing those four components. During the last five years 15500 articles and reviews have been written addressing diabetes and coronary arterial disease, 16100 addressing diabetes and renal function, 28900 addressing diabetes and retinopathy, 16800 addressing diabetic foot ulcers and other 26300 addressing diabetic neuropathy. Moreover 17200 articles are dealing with diabetic sexual dysfunction, 24500 with the correlation of diabetes and depression 17500 about diabetes and dementia, only 1 about diabetes and family functioning and 1950000 about diabetes and QoL, indicating the worldwide interest. In order to confront this metabolic anomaly and its consequences, researchers developed numerous generic and disease specific psychometric tools. With the aid of those psychometric tools the scientific community has started to realize the gruesome effect of diabetes on patients' lives. Diabetic's QoL becomes worse when complications start to develop or comorbidities coexist. Dominant amongst complications, in health-related quality of life(HRQoL) lowering, but not related to risk factors(genetic, the weight of birth, or others) is coronary arterial disease followed by renal failure, blindness, and the combination of micro-and macrovascular complications and in some studies by sexual dysfunction. Moreover many are the comorbidities which deteriorate further the effect of diabetes in a patient life. Among them obesity, hypertension, dyslipidemia, depression, arthritis are the most common. Most intriguing field for research is the interaction of diabetes and depression and in some cases the progression to dementia. Many aspects and combinations of actions are under researche

关键词： Type 2 diabetes Quality of life Diabetes co morbidities Diabetes complications Dementia Diabetes type 3

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Pleural involvement in cryptococcal infection

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World Journal of Clinical Cases 2022年第16期10卷 5510-5514页

作者： Vasiliki E Georgakopoulou Christos Damaskos Pagona Sklapani Nikolaos Trakas aikaterini Gkoufa Department of Infectious Diseases Laiko General HospitalAthens 11527Greece

Pleural involvement of cryptococcal infection is uncommon and is more commonly observed in immunocompromised hosts than in immunocompetent *** involvement in cryptococcal infections can manifest with or without pleural *** presence of Cryptococcus *** the effusion or pleura is required for the diagnosis of cryptococcal pleural infection,which is commonly determined by pleural biopsy,fluid culture,and/or detection of cryptococcal antigen in the pleura or pleural fluid.

关键词： Cryptococcosis Pleural effusion Pleural diseases Fungal lung diseases Pleural Cavity Cryptococcus neoformans

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