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低温弱光保存的海带(Saccharina japonica)雌配子体细胞结构变化

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集美大学学报（自然科学版） 2019年第1期24卷 10-13页

作者：王翔宇于晓清丁刚宋爱环刘洪军山东省海洋生物研究院山东青岛266104

低温弱光保存的部分海带配子体会出现颜色变为浅褐色和白色的现象。以海带雌配子体为对象,采用显微和透射电镜观察的方法,研究不同状态的细胞显微和超微结构。结果发现:颜色变浅的配子体细胞内部分布变得不均匀,出现质壁分离现象,色素... 详细信息

低温弱光保存的部分海带配子体会出现颜色变为浅褐色和白色的现象。以海带雌配子体为对象,采用显微和透射电镜观察的方法,研究不同状态的细胞显微和超微结构。结果发现:颜色变浅的配子体细胞内部分布变得不均匀,出现质壁分离现象,色素体、细胞核和线粒体等细胞器形状变得不规则,色素体片层结构变得模糊;变白的配子体细胞内部空泡化,细胞器完全溶解,或者只残存少量色素体,细胞壁边缘变得粗糙。

关键词：海带雌配子体显微结构超微结构

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脆壳全海笋和宽壳全海笋的营养成分分析

广西科学院学报 2016年第2期32卷 122-128页

作者：张婷婷李莉李琪宋爱环王慧刘洪军山东农业大学动物科技学院山东泰安271018 山东省海洋生物研究院青岛市海洋生物种质资源挖掘与利用工程实验室山东青岛266104 中国海洋大学海水养殖教育部重点实验室山东青岛266003

【目的】对脆壳全海笋（Barnea fragilis）和宽壳全海笋（Barnea diliaia）的营养价值进行综合评价和比较.【方法】采用常规营养指标测定方法对两种海笋的水管组织和内脏团组织的营养成分进行测定.【结果】两种海笋水管的水分和粗蛋白... 详细信息

【目的】对脆壳全海笋（Barnea fragilis）和宽壳全海笋（Barnea diliaia）的营养价值进行综合评价和比较.【方法】采用常规营养指标测定方法对两种海笋的水管组织和内脏团组织的营养成分进行测定.【结果】两种海笋水管的水分和粗蛋白含量高于内脏团,粗脂肪和总糖的含量低于内脏团;两种海笋中,脆壳全海笋两组织的灰分含量较高;两种海笋的水管和内脏团中均含有1 6 种氨基酸,内脏团中必需氨基酸（E s s e n i d a m i -n o a c id ,EAA ）占总氨基酸（T A A ）比例为35. 3 2 % -35. 5 4 % ,与W H O / F A O 推荐模式相近,高于水管;鲜味氨基酸（Delicious amino acid DAA ）占总氨基酸的比例为40. 3 8 % -51. 5 0 % ,其中谷氨酸含量最高,达到1 3 . 6 7 % -1 7 . 0 5 % ; 除宽壳全海笋的水管外,两种海笋氨基酸评分（AAS ）和化学评分（C S ）的第一限制氨基酸均为蛋氨酸＋胱氨酸;矿质元素比例均衡,F e 含量丰富.【结论】两种海笋的水管是高蛋白、低脂肪、味道鲜美、营养丰富的海产品;脆壳全海笋在补充矿物质元素、维持健康方面具有广阔的应用前景;宽壳全海笋在补充蛋白质和食用口感上更优.

关键词：脆壳全海笋宽壳全海笋营养成分营养评价水管内脏团

Neuronal regulated cell death in aging-related neurodegenerative diseases:key pathways and therapeutic potentials

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Neural Regeneration Research 2025年第8期20卷 2245-2263页

作者： Run song Shiyi Yin Jiannan Wu Junqiang Yan Department of Neurology The First Affiliated HospitalCollege of Clinical Medicine of Henan University of Science and TechnologyLuoyangHenan ProvinceChina Neuromolecular Biology Laboratory The First Affiliated HospitalCollege of Clinical Medicine of Henan University of Science and TechnologyLuoyangHenan ProvinceChina

Regulated cell death(such as apoptosis,necroptosis,pyroptosis,autophagy,cuproptosis,ferroptosis,disulfidptosis)involves complex signaling pathways and molecular effectors,and has been proven to be an important regulatory mechanism for regulating neuronal aging and ***,excessive activation of regulated cell death may lead to the progression of aging-related *** review summarizes recent advances in the understanding of seven forms of regulated cell death in age-related ***,the newly identified ferroptosis and cuproptosis have been implicated in the risk of cognitive impairment and neurodegenerative *** forms of cell death exacerbate disease progression by promoting inflammation,oxidative stress,and pathological protein *** review also provides an overview of key signaling pathways and crosstalk mechanisms among these regulated cell death forms,with a focus on ferroptosis,cuproptosis,and *** instance,FDX1 directly induces cuproptosis by regulating copper ion valency and dihydrolipoamide S-acetyltransferase aggregation,while copper mediates glutathione peroxidase 4 degradation,enhancing ferroptosis ***,inhibiting the Xc-transport system to prevent ferroptosis can increase disulfide formation and shift the NADP^(+)/NADPH ratio,transitioning ferroptosis to *** insights help to uncover the potential connections among these novel regulated cell death forms and differentiate them from traditional regulated cell death *** conclusion,identifying key targets and their crosstalk points among various regulated cell death pathways may aid in developing specific biomarkers to reverse the aging clock and treat age-related neurodegenerative conditions.

关键词： apoptosis autophagy cuproptosis disulfidptosis ferroptosis necroptosis neurodegenerative disease neurological aging diseases PANoptosis pyroptosis

Electrochemical conversion of methane to bridge the gap in the artificial carbon cycle

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Journal of Energy Chemistry 2025年第1期100卷 286-308页

作者： Yuhao Peng Yuefeng song Ihar Razanau Juanxiu Xiao Wei Xiao Di Hu Guoxiong Wang College of Chemistry and Molecular Sciences Hubei Key Laboratory of Electrochemical Power Sources Wuhan University State Key Laboratory of Catalysis Dalian National Laboratory for Clean Energy iChEM (Collaborative Innovation Center of Chemistry for Energy Materials) Dalian Institute of Chemical Physics Chinese Academy of Sciences Laboratory of Physical-Chemical Technologies SSPA Scientific and Practical Materials Research Centre of NAS of Belarus State Key Laboratory of Marine Resources Utilization in South China Sea Collaborative Innovation Center of Marine Science and Technology School of Marine Science and Engineering Hainan University Department of Chemical and Environmental Engineering University of Nottingham Ningbo China

Methane, an abundant one-carbon（C1） resource, is extensively used in the industrial production of vital fuels and value-added chemicals. However, current industrial methane conversion technologies are energy-and carbon-intensive, mainly due to the high activation energy required to break the inert C–H bond, low selectivity, and problematic side reactions, including CO2emissions and coke deposition. Electrochemical conversion of methane（ECM） using intermittent renewable energy offers an attractive solution, due to its modular reactor design and operational flexibility across a broad spectrum of temperatures and pressures. This review emphasizes conversion pathways of methane in various reaction systems, highlighting the significance and advantages of ECM in facilitating a sustainable artificial carbon cycle. This work provides a comprehensive overview of conventional methane activation mechanisms and delineates the complete pathways of methane conversion in electrolysis contexts. Based on surface/interface chemistry, this work systematically analyzes proposed reaction pathways and corresponding strategies to enhance ECM efficiency towards various target products, including syngas, hydrocarbons, oxygenates, and advanced carbon materials. The discussion also encompasses opportunities and challenges for the ECM process, including insights into ECM pathways, rational electrocatalyst design, establishment of benchmarking protocols, electrolyte engineering, enhancement of CH4conversion rates, and minimization of CO2emission.

关键词： Methane Electrochemical conversion Reaction mechanism Catalyst design Electrode Electrocatalysis

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山东省海洋牧场建设浅析

海洋开发与管理 2017年第A2期34卷 16-19页

作者：郑永允宋爱环吴莹莹邹琰王英俊于倩倩宋强山东省海洋生物研究院青岛266104 山东省海洋发展研究会青岛266104 青岛市海洋生物种质资源挖掘与利用工程实验室青岛266104

文章系统梳理了海洋牧场的概念以及国内外海洋牧场的发展概况,并详细分析了山东省海洋牧场建设的发展现状.加强海洋牧场建设将推动山东省继藻、贝、虾、鱼、参五次海水养殖浪潮之后的第六次海水养殖浪潮的发展.

关键词：海洋牧场海水养殖浪潮

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山东省近海主要海洋捕捞经济鱼类资源变动分析

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广西科学院学报 2019年第4期35卷 301-307页

作者：邹琰刘童王英俊吴莹莹刘翠玲宋爱环山东省海洋生物研究院青岛市海洋生物种质资源挖掘与利用工程实验室

根据山东省1996-2017年渔业统计数据,对山东省11种主要经济海洋鱼类捕捞量的变动与鱼种结构进行分析,并结合捕捞方式,讨论4个优势种捕捞量变化的原因。结果表明:山东近海主要经济鱼类的捕捞总量在1996-1999年保持增长态势,之后下降明显... 详细信息

根据山东省1996-2017年渔业统计数据,对山东省11种主要经济海洋鱼类捕捞量的变动与鱼种结构进行分析,并结合捕捞方式,讨论4个优势种捕捞量变化的原因。结果表明:山东近海主要经济鱼类的捕捞总量在1996-1999年保持增长态势,之后下降明显;鱼种结构的多样性与均匀性不断增加;经多年捕捞利用,蓝点马鲛、带鱼衰退明显,个体趋于小型化;鳀鱼在2003年以后虽然出现衰退现象,但生殖力明显增大。总之,山东近海主要经济鱼类资源总量整体呈下降趋势,蓝点马鲛、带鱼、鳀鱼仍处于衰退状态,需要加强保护。

关键词：山东省海洋捕捞经济鱼类鱼类资源鱼种结构

Passive activity enhances residual control ability in patients with complete spinal cord injury

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Neural Regeneration Research 2025年第8期20卷 2337-2347页

作者： Yanqing Xiao Mingming Gao Zejia He Jia Zheng Hongming Bai Jia-Sheng Rao Guiyun song Wei song Xiaoguang Li Beijing Key Laboratory for Biomaterials and Neural Regeneration Beijing Advanced Innovation Center for Biomedical EngineeringSchool of Biological Science and Medical EngineeringBeihang UniversityBeijingChina Department of Rehabilitation Evaluation China Rehabilitation Research CenterBeijingChina Cardiac Center Beijing Children’s HospitalCapital Medical UniversityBeijingChina The State Key Laboratory of Virtual Reality Technology and Systems Beihang UniversityBeijingChina Department of Rehabilitation Engineering China Rehabilitation Science InstituteBeijingChina

Patients with complete spinal cord injury retain the potential for volitional muscle activity in muscles located below the spinal injury ***,because of prolonged inactivity,initial attempts to activate these muscles may not effectively engage any of the remaining neurons in the descending pathway.A previous study unexpectedly found that a brief clinical round of passive activity significantly increased volitional muscle activation,as measured by surface *** this study,we further explored the effect of passive activity on surface electromyographic signals during volitional control tasks among individuals with complete spinal cord *** patients with chronic complete thoracic spinal cord injury were *** electromyography data from eight major leg muscles were acquired and compared before and after the passive activity *** results indicated that the passive activity led to an increased number of activated volitional muscles and an increased frequency of *** the cumulative root mean square of surface electromyography amplitude for volitional control of movement showed a slight increase after passive activity,the difference was not statistically *** findings suggest that brief passive activity may enhance the ability to initiate volitional muscle activity during surface electromyography tasks and underscore the potential of passive activity for improving residual motor control among patients with motor complete spinal cord injury.

关键词： complete spinal cord injury cycle training epidural electrical stimulation motor training passive activity physiological state spinal cord circuit surface electromyography volitional control task

Calcium channels caught in peripheral glia’s tug-of-war on axon regeneration in Drosophila

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Neural Regeneration Research 2025年第2期20卷 475-476页

作者： Jackson Powell Tobias Steinschaden Rose Horowitz Yuanquan song Raymond G.Perelman Center for Cellular and Molecular Therapeutics The Children’s Hospital of PhiladelphiaPhiladelphiaPAUSA The Neuroscience Graduate Group University of PennsylvaniaPhiladelphiaPAUSA Department of Pathology and Laboratory Medicine University of PennsylvaniaPhiladelphiaPAUSA Medical University of Vienna Center for Brain ResearchDepartment of NeuroimmunologyViennaAustria

Neural damage or degeneration is at the crux of many diseases,and treatment of these diseases will require the development of therapeutics to enhance and guide neural *** intrinsic and extrinsic factors dictate a neuron’s ability to regenerate,and the combination of these factors results in the great regenerative capacity of the peripheral nervous system(PNS)and the poor regenerative capacity of the central nervous system(CNS)following *** the core of a neuron’s function is its ability to relay electrochemical signals,and a neuron’s excitability is a key factor in its ability to *** works have focused on the changes in neuronal electrophysiological properties,firing patterns,and ion flux after injury,which differentially activate signaling pathways at the core of *** role of glia in neuron regeneration has long been studied.

关键词： degeneration firing system

芽孢杆菌组合对海水养殖水体COD的降解效果

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广西科学院学报 2016年第3期32卷 215-220页

作者：辛美丽宋爱环王志刚胡凡光逄劭楠孙福新山东省海洋生物研究院山东青岛266104

【目的】获得一种降解性能优于单菌株的菌株组合,更好地改善目前工业化密度养殖的水体水质。【方法】从刺参(Stichopus japonicus)养殖池塘分离降解效果良好的单菌株,根据菌株之间的拮抗效应,按照2株菌或3株菌进行组合,研究各组合菌株... 详细信息

【目的】获得一种降解性能优于单菌株的菌株组合,更好地改善目前工业化密度养殖的水体水质。【方法】从刺参(Stichopus japonicus)养殖池塘分离降解效果良好的单菌株,根据菌株之间的拮抗效应,按照2株菌或3株菌进行组合,研究各组合菌株的降解效果。【结果】2株菌的组合第6天时COD含量的均值为422.57mg/L,标准差为63.85,3株菌的组合第6天时COD含量的均值为365.61mg/L,标准差为67.63,说明3株菌的组合整体降解效果比2株菌的组合好,且更容易获得降解效率高的组合,但并不是所有3株菌的组合降解效果都优于2株菌的组合。【结论】确定最优菌株组合为C14(菌株B2,菌株B6,菌株B11),COD降解率为64.29%。经鉴定,菌株B2为枯草芽孢杆菌(Bacillus subtilis),菌株B6为巨大芽孢杆菌(Bacillus megaterium),菌株B11为嗜碱性芽孢杆菌(Bacillus alcalophilus),为今后的实践应用提供参考。

关键词：芽孢杆菌降解性能组合