检索结果-南通市图书馆

Impact of direct-acting antiviral regimens on hepatic and extrahepatic manifestations of hepatitis C virus infection

引用

World Journal of Hepatology 2022年第6期14卷 1053-1073页

作者： Iman Ibrahim Salama Hala m Raslan Ghada A Abdel-Latif Somaia I Salama Samia m Sami Fatma A Shaaban aida m abdelmohsen Walaa A Fouad Department of Community medicine Research National Research CenterGiza 12622DokkiEgypt Department of Internal medicine National Research CenterGiza 12622DokkiEgypt Department of Child Health National Research CenterGiza 12622DokkiEgypt

Hepatitis C virus(HCV)is a common cause of liver disease and is associated with various extrahepatic manifestations(EHms).This mini-review outlines the currently available treatments for HCV infection and their prognostic effect on hepatic manifestations and ***-acting antiviral(DAA)regimens are considered pan-genotypic as they achieve a sustained virological response(SVR)>85%after 12 wk through all the major HCV genotypes,with high percentages of SVR even in advanced fibrosis and *** risk factors for DAA failure include old males,cirrhosis,and the presence of resistance-associated substitutions(RAS)in the region targeted by the received *** effectiveness of DAA regimens is reduced in HCV genotype 3 with baseline RAS like A30K,Y93H,and ***,the European Association for the Study of the Liver recommended the identification of baseline RAS for HCV genotype *** higher rate of hepatocellular carcinoma(HCC)after DAA therapy may be related to the fact that DAA regimens are offered to patients with advanced liver fibrosis and cirrhosis,where interferon was contraindicated to those *** change in the growth of pre-existing subclinical,undetectable HCC upon DAA treatment might be also a ***,after DAA therapy,the T cell-dependent immune response is much weaker upon HCV clearance,and the down-regulation of TNF-αor the elevated neutrophil to lymphocyte ratio might increase the risk of *** can result in reactivation of hepatitis B virus(HBV)in HCV coinfected *** are effective in treating HCV-associated mixed cryoglobulinemia,with clinical and immunological responses,and have rapid and high effectiveness in *** improve insulin resistance in 90%of patients,increase glomerular filtration rate,and decrease proteinuria,hematuria and articular *** clearance by DAAs allows a significant improvement in atherosclerosis and metabolic and immunological conditions,with a reduction of m

关键词： Hepatitis C virus Hepatic Extrahepatic Direct-acting antivirals Impact

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Current and novel modalities for management of chronic hepatitis B infection

引用

World Journal of Hepatology 2023年第5期15卷 585-608页

作者： Iman Ibrahim Salama Samia m Sami Somaia I Salama Ghada A Abdel-Latif Fatma A Shaaban Walaa A Fouad aida m abdelmohsen Hala m Raslan Department of Community medicine Research National Research CentreGiza 12411DokkiEgypt Department of Child Health National Research CentreGiza 12411DokkiEgypt Department of Internal medicine National Research CentreGiza 12411DokkiEgypt

Over 296 million people are estimated to have chronic hepatitis B viral infection(CHB),and it poses unique challenges for *** is the result of hepatitis B virus(HBV)-specific immune tolerance and the presence of covalently closed circular DNA as mini chromosome inside the nucleus and the integrated *** hepatitis B core-related antigen is the best surrogate marker for intrahepatic covalently closed circular *** HBV“cure”is the durable loss of hepatitis B surface antigen(HBsAg),with or without HBsAg seroconversion and undetectable serum HBV DNA after completing a course of *** currently approved therapies are nucleos(t)ide analogues,interferon-alpha,and *** these therapies,functional cure can be achieved inmmune system that disrupts the interaction between them can lead to reactivation of *** therapies may allow efficient control of *** include direct acting antivirals and *** of the viral antigen load is a crucial factor for success of immune-based *** therapy may lead to modulation of the host immune *** may enhance/restore innate immunity against HBV(as toll-like-receptors and cytosolic retinoic acid inducible geneⅠagonist).Others may induce adaptive immunity as checkpoint inhibitors,therapeutic HBV vaccines including protein(HBsAg/pre S and hepatitis B core antigen),monoclonal or bispecific antibodies and genetically engineered T cells to generate chimeric antigen receptor-T or T-cell receptor-T cells and HBV-specific T cells to restore T cell function to efficiently clear *** therapy may successfully overcome immune tolerance and lead to HBV control and *** approaches carry the risk of overshooting immune responses causing uncontrolled liver *** safety of any new curative therapies should be measured in relation to the excellent safety of currently appro

关键词： immunity infection overcome

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Sports Prediction model through Cloud Computing and Big Data Based on Artificial Intelligence method

引用

Journal of Intelligent Learning Systems and Applications 2024年第2期16卷 53-79页

作者： Aws I. Abu Eid Achraf Ben miled Ahlem Fatnassi majid A. Nawaz Ashraf F. A. mahmoud Faroug A. Abdalla Chams Jabnoun aida Dhibi Firas m. Allan mohammed Ahmed Elhossiny Salem Belhaj Imen Ben mohamed Faculty of Computing Studies Arab Open University Amman Jordan Computer Science Department Science College Northern Border University Arar Kingdom of Saudi Arabia Artificial Intelligence and Data Engineering Laboratory LR21ES23 Faculty of Sciences of Bizerte University of Carthage Tunis Tunisia Applied College Northern Border University Arar Kingdom of Saudi Arabia Faculty of Specific Education Mansoura University Mansoura Egypt

This article delves into the intricate relationship between big data, cloud computing, and artificial intelligence, shedding light on their fundamental attributes and interdependence. It explores the seamless amalgamation of AI methodologies within cloud computing and big data analytics, encompassing the development of a cloud computing framework built on the robust foundation of the Hadoop platform, enriched by AI learning algorithms. Additionally, it examines the creation of a predictive model empowered by tailored artificial intelligence techniques. Rigorous simulations are conducted to extract valuable insights, facilitating method evaluation and performance assessment, all within the dynamic Hadoop environment, thereby reaffirming the precision of the proposed approach. The results and analysis section reveals compelling findings derived from comprehensive simulations within the Hadoop environment. These outcomes demonstrate the efficacy of the Sport AI model (SAIm) framework in enhancing the accuracy of sports-related outcome predictions. Through meticulous mathematical analyses and performance assessments, integrating AI with big data emerges as a powerful tool for optimizing decision-making in sports. The discussion section extends the implications of these results, highlighting the potential for SAIm to revolutionize sports forecasting, strategic planning, and performance optimization for players and coaches. The combination of big data, cloud computing, and AI offers a promising avenue for future advancements in sports analytics. This research underscores the synergy between these technologies and paves the way for innovative approaches to sports-related decision-making and performance enhancement.

关键词： Artificial Intelligence machine Learning Spark Apache Big Data SAIm

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A New Reliable System For managing Virtual Cloud Network

引用

Computers, materials & Continua 2022年第12期73卷 5863-5885页

作者： Samah Alshathri Fatma m.Talaat aida A.Nasr Department of Information Technology College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh 11671Saudi Arabia Faculty of Artificial Intelligence Kafrelsheikh UniversityKafrelsheikhEgypt Faculity of Computers and Informatics Tanta UniversityTantaEgypt

Virtual cloud network(VCN)usage is popular today among large and small organizations due to its safety and ***,it makes all resources in the company work as one *** also facilitates sharing of files and applications without ***,cloud providers face many issues in managing the VCN on cloud computing including these issues:Power consumption,network failures,and data *** issues often occur due to overloaded and unbalanced load *** this paper,we propose a new automatic system to manage VCN for executing the *** new system calledmulti-User Hybrid Scheduling(mUSH)can solve running issues and save power during workflow *** consists of three phases:Initialization,virtual machine allocation,and task scheduling *** mUSH system focuses on the execution of the workflow with deadline ***,it considers the utilization of virtual *** new system can save makespan and increase the throughput of the execution operation.

关键词： Virtual network scheduling reliability Vm allocation cloud computing

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Fusion Strategy for Improving medical Image Segmentation

引用

Computers, materials & Continua 2023年第2期74卷 3627-3646页

作者： Fahad Alraddady E.A.Zanaty aida HAbu bakr Walaa m.Abd-Elhafiez Department of Computer Engineering College of Computers and Information TechnologyTaif UniversityTaif21944Saudi Arabia Information System Department Faculty of Computers and InformationSohag UniversitySohagEgypt mathematical and Computer Science Department Faculty of ScienceAswan UniversityAswanEgypt College of Computer Science&Information Technology Jazan UniversityJazanKingdom of Saudi Arabia Computer Science Department Faculty of Computers and Artificial IntelligenceSohag UniversitySohagEgypt

In this paper,we combine decision fusion methods with four metaheuristic algorithms(Particle Swarm Optimization(PSO)algorithm,Cuckoo search algorithm,modification of Cuckoo Search(CS mcCulloch)algorithm and Genetic algorithm)in order to improve the image *** proposed technique based on fusing the data from Particle Swarm Optimization(PSO),Cuckoo search,modification of Cuckoo Search(CS mcCulloch)and Genetic algorithms are obtained for improving magnetic resonance images(mRIs)*** algorithms are used to compute the accuracy of each method while the outputs are passed to fusion *** order to obtain parts of the points that determine similar membership values,we apply the different rules of incorporation for these *** proposed approach is applied to challenging applications:mRI images,gray matter/white matter of brain segmentations and original black/white images Behavior of the proposed algorithm is provided by applying to different medical *** is shown that the proposed method gives accurate results;due to the decision fusion produces the greatest improvement in classification accuracy.

关键词： Decision fusion particle swarmoptimization(PSO) cuckoo search algorithm CS mcCulloch algorithm genetic algorithm CT and mRI

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

mechanism of selective hydrolysis of alginates under hydrothermal conditions

引用

Journal of Bioresources and Bioproducts 2022年第3期7卷 173-179页

作者： Taku michael aida Yasuaki Kumagai Richard Lee Smith Jr Department of Chemical Engineering Faculty of EngineeringFukuoka UniversityNanakuma Jonan-kuFukuoka 814-0180Japan Research Center of Composite material Fukuoka UniversityNanakuma Jonan-kuFukuoka814-0180Japan Graduate School of Environmental Studies Tohoku UniversityAoba-kuSendai980-8579Japan

mechanisms of selective hydrolysis of alginates under hydrothermal conditions were investigated by comparing reactivities of sodium alginate(Na-ALG,960 ku)solutions and calcium alginate(Ca-ALG)gels as *** hydrothermal conditions(150°C),hydrolysis of Na-ALG gave product molecular weights of 223,66,26 and 17 ku while those of Ca-ALG gave product molecular weights of 340,102,45 and 31 ku for reaction times of 10,20,30 and 60 min,*** ratios of mannuronic acid(m)to guluronic acid(G)varied only slightly(from 1.3 to 1.2)for Na-ALG over the range of reaction times at 150°C,while ratios(m/G)for Ca-ALG exhibited a remarkable decrease(from 1.1 to 0.8).Diad sequence of alginate products obtained for Na-ALG were 17%,23%,27%and 31%(GG);30%,32%,36%and 38%(mm);and 53%,46%,37%and 32%(Gm+mG);while for Ca-ALG they were 18%,22%,24%and 33%(GG);26%,23%,26%and 18%(mm);and 56%,54%,50%and 48%(Gm+mG).Reaction mechanisms are proposed for hydrolysis of alginate solutions and alginate gels under hydrothermal conditions;de-polymerization of alginates into monomers and monomeric sequences can be controlled not only by hydrothermal conditions,but also by varying the physical state(solution,gel)of the starting materials.

关键词： Biomaterial Biopolymer De-polymerization High temperature water

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

microstructure and phase formation of mullite-Pr6O11 composite prepared by spark plasma sintering

引用

Journal of Rare Earths 2023年第2期41卷 283-289页

作者： Ehsan Ghasali Davoud Ghahremani Yasin Orooji aida Faeghi-nia Asghar Kazem-zadeh Touradj Ebadzadeh College of Geography and Environmental Sciences Zhejiang Normal UniversityJinhua 321004China Ceramic Dept. Materials and Energy Research CenterAlborzIran Department of Engineering Maybod BranchIslamic Azad UniversityMaybodIran

The present work investigates the effect of high praseodymium oxide(Pr6O11)content on the microstructure and phase formation of mullite(3Al_(2)O_(3)·2SiO_(2))precursor by means of the spark plasma sintering process.30 wt%Pr6O11was added to a mullite precursor consisting of aluminum nitrate nonahydrate and tetraethyl orthosilicate through a high energy mixer mill in ethanol *** spark plasma sintering was performed at a te mperature of 1200℃under 23 Pa vacuum co nditions by applying initial and final pressure of 10 and 30 mPa,*** analysis confirms the existence of mullite,alumina,Pr6O11,Pr2O3and quartz as the only crystalline *** images reveal an interesting deposition of hexagonal-shaped Al_(2)O_(3)particles on polished surfaces and complex oxide phases of the fiber network adhering to alumina particles in the form of tails seen on the fracture ***,the bending strength of 213±21 mPa,Vickers hardness of 9.3±0.1 mPa and fracture toughness of6.21±0.12 mPa·m1/2are obtained for the prepared composite.

关键词： mullite Pr6O11 Composite Spark plasma sintering Rare earths

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effect of Fibre Size on mechanical Properties and Surface Roughness of PLA Composites by Using Fused Deposition modelling (FDm)

引用

Journal of Renewable materials 2023年第8期11卷 3261-3276页

作者： aida Haryati Jamadi Nadlene Razali Sivakumar Dhar malingam mastura mohammad Taha Fakulti Kejuruteraan mekanikal Universiti Teknikal Malaysia MelakaHang Tuah JayaDurian TunggalMelaka76100Malaysia Fakulti Teknologi Kejuruteraan mekanikal dan Pembuatan Universiti Teknikal Malaysia MelakaHang Tuah JayaDurian TunggalMelaka76100Malaysia Centre for Advanced Research on Energy Universiti Teknikal Malaysia MelakaHang Tuah JayaDurian TunggalMelaka76100Malaysia

Naturalﬁbre as a reinforcing agent has been widely used in many industrial ***,several factors need to be considered,such as the size and weight percentage of theﬁbre used in *** fused deposition modelling(FDm),this factor was investigated by varying the size of naturalﬁbre as the responding variable with aﬁxed weight percentage of kenafﬁ*** process of modifying the naturalﬁbre in terms of size might increase the dispersion of kenafﬁbre in the polymer matrix and increase the adhesion bonding between theﬁbre and matrix of composites,subsequently improving the interfacial bonding between these two *** this paper,the effect ofﬁbre size was evaluated by performing the mechanical test,Scanning Electron micrograph(SEm)to observe the morphology of the composites,and also by surface *** surface roughness was visualised using a 3D proﬁlometer and theﬁgure was illustrated as colour shading in the *** composite withﬁbre size≤100μm displayed better tensile andﬂexural strength,compared to other *** conclusion,by reducing the size of theﬁbre,the composites could develop high strength performance for industrial applications.

关键词： Fibre size mechanical properties fused deposition modelling(FDm) surface analysis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

ZnS thin films deposition by thermal evaporation for photovoltaic applications

引用

Journal of Semiconductors 2015年第10期36卷 41-44页

作者： K.Benyahia A.Benhaya m.S.aida Electrical Engineering Department University of Hadj Lakhdar Batna Head of Clean Room LEA LaboratoryUniversity of Hadj Lakhdar Batna Physics Department University of Constantine 1Algeria

ZnS thin films were deposited on glass substrates by thermal evaporation from millimetric crystals of ZnS. The structural, compositional and optical properties of the films are studied by X-ray diffraction, SEm microscopy, and UV-VIS spectroscopy. The obtained results show that the films are pin hole free and have a cubic zinc blend structure with （111） preferential orientation. The estimated optical band gap is 3.5 eV and the refractive index in the visible wavelength ranges from 2.5 to 1.8. The good cubic structure obtained for thin layers enabled us to conclude that the prepared ZnS films may have application as buffer layer in replacement of the harmful CdS in CIGS thin film solar cells or as an antireflection coating in silicon-based solar cells.

关键词： ZnS thin films thermal evaporation buffer layer antireflection coating

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Films surface temperature calculation during growth by sputtering technique

引用

Journal of Semiconductors 2017年第9期38卷 82-85页

作者： F.Khelfaoui m.S.aida Universit6 Abbes Laghrour Khenchela Algerie Department of Physics Faculty of SciencesKing Abdulaziz UniversityDjeddahKSA

A calculation of film surface temperature during thin films growth by sputtering technique is proposed. The calculation procedure is based on the conversion into heat of the total flux energy of species impinging the film surface during growth. The results indicate that the film＇s surface temperature depends drastically on material substrate thermal conductivity and thickness on one hand, and the plasma conditions namely the discharge power on the other. The predicted film surface temperatures were used to explain the microstructure evolution of hydro- genated amorphous silicon （a-Si：H） thin films deposited by reactive radio frequency （RF） sputtering on different substrates.

关键词： sputtering deposition plasma amorphous silicon thin films

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：