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Luminescent Zinc Porphyrinic MOF as a Ratiometric Fluorescence Sensor for Determination of Tetracycline Hydrochloride

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Food Science and human Wellness 2024年

作者： Quanbin Fu Feijiao hu Wenyuan Tan Qiaofeng Zhai Juying Hou Houshen Li Zhiyong hu Yijing Li Geoffrey I.N.Waterhouse Shiyun ai College of Food Science and Engineering， Shandong Agricultural University College of Chemistry and Material Science， Shandong Agricultural University Sichuan Engineering Technology Research Center for High Salt Wastewater Treatment and Resource Utilization， Sichuan University of Science and Engineering Tai'an Planning and Compilation Research Center (Tai'an institute of Planning and Design Tai'an Planning Exhibition Hall) College of Animal Science and Technology， Shandong Agricultural University School of Chemical Sciences， The University of Auckland

Two-dimensional luminescent metal-organic frameworks （2D LMOFs）， have garnered significant attention for their unique fluorescent properties and highly accessible active sites， yet designing these LMOFs with target-dependent fluorescence for sensing remains a challenging endeavor. Herein， a zinc tetra（4-carboxyphenyl）porphine （Zn-TCPP） LMOF was prepared and first applied to the fast and sensitive sensing of tetracycline hydrochloride （TCH）. Upon TCH exposure， the signature red fluorescence of Zn-TCPP at 609 nm diminishes， accompanied by the emergence of a 520 nm peak， which were originated from photo-induced electron transfer （PET） of Zn-TCPP to TCH and inner filter effect （IFE） of TCH towards Zn-TCPP， and the triggers of Zn-TCPP on the instinct fluorescence of TCH， respectively. Notably， the I520/I609fluorescence intensity ratio showed good linearity over a wide range of TCH concentrations （0.1-25 μmol/L）， with a limit of detection （LOD） of 65.4 nmol/L. Additionally， the Zn-TCPP probe showed good TCH selectivity and anti-interference properties. The probe’s practicability was also validated by detecting TCH in spiked tap water， milk and chicken samples. Furthermore， test papers impregnated with the Zn-TCPP probe were prepared， allowing the visual detection of TCH with a smartphone. Results suggest the developed method is suitable for practical TCH detection.

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“哪”作为疑问代词书写规范的形成与确立

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中国语文 2024年第5期 630-637,640页

作者：胡习之高群阜阳师范大学文学院阜阳

疑问代词“那”的分化,从1919年蔡晓舟提倡用“哪”,再到二十世纪六七十年代“哪”最终完全取代“那”而成为唯一的规范书写形式,经历了四五十年的实践过程。1956年暂拟汉语教学语法系统的制定,尤其是中学《汉语》课本对疑问代词书写形... 详细信息

疑问代词“那”的分化,从1919年蔡晓舟提倡用“哪”,再到二十世纪六七十年代“哪”最终完全取代“那”而成为唯一的规范书写形式,经历了四五十年的实践过程。1956年暂拟汉语教学语法系统的制定,尤其是中学《汉语》课本对疑问代词书写形式的选用标志着“哪”作为疑问代词书写规范的最终确立,至二十世纪六七十年代最后成为全民自觉的书写规范。

关键词：疑问代词哪书写规范形成确立

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城市固废焚烧过程炉温与烟气含氧量多目标鲁棒预测模型

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自动化学报 2024年第5期50卷 1001-1014页

作者：胡开成严爱军汤健北京工业大学信息学部北京100124 数字社区教育部工程研究中心北京100124 城市轨道交通北京实验室北京100124

为实现城市固废焚烧(Municipal solid waste incineration,MSWI)过程炉温与烟气含氧量的准确预测,提出一种基于改进随机配置网络的多目标鲁棒建模方法(Multi-target robust modeling method based on improved stochastic configuration network,MRI-SCN).首先,设计了一种并行方式增量构建SCN隐含层,通过信息叠加与跨越连接来增强隐含层映射多样性,并利用参数自适应变化的监督不等式分配隐含层参数;其次,使用F范数与L_(2,1)范数正则项建立矩阵弹性网对模型参数进行稀疏约束,以建模炉温与烟气含氧量间的相关性;接着,采用混合拉普拉斯分布作为每个目标建模误差的先验分布,通过最大后验估计重新评估SCN模型的输出权值,以增强其鲁棒性;最后,利用城市固废焚烧过程的历史数据对所提建模方法的性能进行测试.实验结果表明,所提建模方法在预测精度与鲁棒性方面具有优势.

关键词：城市固废焚烧炉温烟气含氧量随机配置网络隐含层并行构造多目标鲁棒建模

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弱势群体社区学习共同体建设的价值、面临的困境及发展路径研究

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成人教育 2024年第9期44卷 25-31页

作者：李倩邵艾群四川师范大学教育科学学院成都610066

社区学习共同体打破了传统社区教育自上而下的开展模式,为弱势群体参与社区学习提供了新机遇。这不仅有利于为弱势群体提供优质学习服务,而且有利于弱势群体融入社会、激发弱势群体发展动力。然而,在国际视野下,我国弱势群体社区学习共... 详细信息

社区学习共同体打破了传统社区教育自上而下的开展模式,为弱势群体参与社区学习提供了新机遇。这不仅有利于为弱势群体提供优质学习服务,而且有利于弱势群体融入社会、激发弱势群体发展动力。然而,在国际视野下,我国弱势群体社区学习共同体存在参与度不高、缺乏制度法律支撑、缺乏充足资源保障等问题。鉴于此,可以从强化组织成员能力建设、丰富学习内容与方式、完善制度与法律、构建多主体学习支持体系等四个方面来拓展弱势群体社区学习共同体的建设路径。

关键词：弱势群体社区学习共同体社区教育

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Surgical treatment of liver cancer and pancreatic cancer under the China Healthcare Security Diagnosis Related Groups payment system

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World Journal of Clinical Cases 2024年第21期12卷 4673-4679页

作者： Yun-He hu Fan Yu Yu-Zhuo Zhou ai-Dong Li National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China

BACKGROUND Data from the World Health Organization’s International Agency for Research on Cancer reported that China had the highest prevalence of cancer and cancer deaths in *** and pancreatic cancers accounted for the highest number of new ***-world data(RWD)is now widely preferred to traditional clinical trials in various fields of medicine and healthcare,as the traditional research approach often involves highly selected populations and interventions and controls that are strictly ***,research results from the RWD match global reality better than those from traditional clinical *** To analyze the cost disparity between surgical treatments for liver and pancreatic cancer under various *** This study analyzed RWD 1137 cases within the HB1 group(patients who underwent pancreatectomy,hepatectomy,and/or shunt surgery)in *** distinguished different expenditure categories,including medical,nursing,technical,management,drug,and consumable ***,it assessed the contribution of each expenditure category to total hospital costs and performed cross-group comparisons using the non-parametric Kruskal–Wallis *** study used the Steel–Dwass test for post-hoc multiple comparisons and the Spearman correlation coefficient to examine the relationships between *** The study found that in HB11 and HB13,the total hospitalization costs were significantly higher for pancreaticoduodenectomy than for pancreatectomy and *** no significant difference was observed in the length of hospital stay between patients who underwent pancreaticoduodenectomy and pancreatectomy,both were significantly longer than those who underwent liver *** HB15,no significant difference was observed in the total cost of hospitalization between pancreaticoduodenectomy and pancreatectomy;however,both were significantly higher than those in ***,the length of hospital stay was significan

关键词： China health care security diagnosis-related groups Real-world study Liver cancer surgical treatment Pancreatic cancer surgical treatment Hospitalization costs Cost structure Average length of stay

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Advances in Deep-Learning-based Precipitation Nowcasting Techniques

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Journal of Tropical Meteorology 2024年第3期30卷 337-350页

作者： ZHENG qun LIU Qi LAO Ping LU Zhen-ci School of Earth and Space Sciences/CMA-USTC Laboratory of Fengyun Remote Sensing University of Science and Technology of ChinaHefei 230026 China

Precipitation nowcasting,as a crucial component of weather forecasting,focuses on predicting very short-range precipitation,typically within six *** approach relies heavily on real-time observations rather than numerical weather *** core concept involves the spatio-temporal extrapolation of current precipitation fields derived from ground radar echoes and/or satellite images,which was generally actualized by employing computer image or vision ***,with stirring breakthroughs in artificial intelligence(ai)techniques,deep learning(DL)methods have been used as the basis for developing novel approaches to precipitation *** progress has been obtained in recent years,manifesting the strong potential of DL-based nowcasting models for their advantages in both prediction accuracy and computational *** paper provides an overview of these precipitation nowcasting approaches,from which two stages along the advancing in this field *** models that were established on an elementary neural network dominated in the first stage,while large meteorological models that were based on complex network architectures prevailed in the *** particular,the nowcasting accuracy of such data-driven models has been greatly increased by imposing suitable physical *** integration of ai models and physical models seems to be a promising way to improve precipitation nowcasting techniques further.

关键词： precipitation nowcasting deep learning neural network classic model large model

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GhWDL3 is involved in the formation and development of fiber cell morphology in upland cotton(Gossypium hirsutum L.)

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Journal of Cotton Research 2024年第1期7卷 58-68页

作者： CHEN Baojun TIAN Zailong FU Guoyong ZHANG ai SUN Yaru WANG Jingjing PAN Zhaoe LI Hongge hu Daowu XIA Yingying HE Shoupu DU Xiongming Zhengzhou Research Base National Key Laboratory of Cotton Bio-Breeding and Integrated UtilizationZhengzhou UniversityZhengzhouHenan 450001China National Key Laboratory of Cotton Bio-Breeding and Integrated Utilization Institute of Cotton ResearchChinese Academy of Agricultural SciencesAnyangHenan 455000China National Supercomputing Center in Zhengzhou Zhengzhou UniversityZhengzhouHenan 450001China

Background Cotton fiber is a model tissue for studying microtubule-associated proteins(MAPs).The Xklp2(TPX2)proteins that belong to the novel MAPs member mainly participate in the formation and development of microtubule(MT).However,there is a lack of studies concerning the systematic characterization of the TPX2 genes family in ***,the identification and portrayal of *** TPX2 genes can provide key targets for molecular manipula-tion in the breeding of cotton fiber *** In this study,TPX2 family genes were classified into two distinct subclasses TPXLs and MAP genes WAVE DAMP-ENED2-LIKE(WDLs)and quite conservative in ***3 was significantly up-regulated in 15 days post anthe-sis fibers of ZRI-015(an upland cotton with longer and stronger fiber).GhWDL3 promotes all stem hairs to become straight when overexpressed in Arabidopsis,which may indirectly regulate cotton fiber cell morphology during fiber *** induced gene silencing(VIGS)results showed that GhWDL3 inhibited fiber cell elongation at fiber development periods through regulating the expression of cell wall related *** These results reveal that GhWDL3 regulated cotton fiber cell elongation and provide crucial information for the further investigation in the regulatory mechanisms/networks of cotton fiber length.

关键词： Upland cotton GhWDL3 Fiber length TPX2 Cytoskeleton Microtubule-associated proteins(MAPs)

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Dynamic intrauterine crosstalk promotes porcine embryo implantation during early pregnancy

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Science China(Life Sciences) 2024年第8期67卷 1676-1696页

作者： Xupeng Zang Shengchen Gu Wenjing Wang Junsong Shi Jianyu Gan qun hu Chen Zhou Yue Ding Yanjuan He Lei Jiang Ting Gu Zheng Xu Sixiu huang huaqiang Yang Fanming Meng Zicong Li Gengyuan Cai Linjun Hong Zhenfang Wu State Key Laboratory of Swine and Poultry Breeding Industry National Engineering Research Center for Breeding Swine IndustryCollege of Animal ScienceSouth China Agricultural UniversityGuangzhou 510642China Guangdong Provincial Key Laboratory of Agro-Animal Genomics and Molecular Breeding South China Agricultural UniversityGuangzhou 510642China Yunfu Subcenter of Guangdong Laboratory for Lingnan Modern Agriculture Yunfu 527300China Guangdong Key Laboratory of Animal Breeding and Nutrition Institute of Animal ScienceGuangdong Academy of Agricultural SciencesGuangzhou 510640China Key Laboratory of South China Modern Biological Seed Industry Ministry of Agriculture and Rural AffairsGuangzhou 510520China

Dynamic crosstalk between the embryo and mother is crucial during ***,we comprehensively profile the single-cell transcriptome of pig peri-implantation embryos and corresponding maternal endometrium,identifying 4 different lineages in embryos and 13 cell types in the ***-specific gene expression characterizes 4 distinct trophectoderm subpopulations,showing development from undifferentiated trophectoderm to polar and mural *** expression of genes in different types of endometrial cells illustrates their molecular response to embryos during ***,we developed a novel tool,ExtraCellTalk,generating an overall dynamic map of maternal-foetal crosstalk using uterine luminal proteins as *** cross-species comparisons,we identified a conserved RBP4/STRA6 pathway in which embryonic-derived RBP4 could target the STRA6 receptor on stromal cells to regulate the interaction with other endometrial *** results provide insight into the maternal-foetal crosstalk during embryo implantation and represent a valuable resource for further studies to improve embryo implantation.

关键词： endometrial remodeling ExtraCellTalk implantation maternal-foetal crosstalk trophoblast

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长持时地震动对建筑结构抗震影响的研究进展

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工程力学 2024年第9期41卷 18-30页

作者：王维李爱群王星星江苏科技大学土木工程与建筑学院江苏镇江212000 东南大学土木工程学院江苏南京210096 北京建筑大学北京未来城市设计高精尖创新中心北京100044

该文综述了长持时地震动作用下建筑结构抗震性能的研究进展。介绍了长持时地震动的定义和特性;梳理了长持时地震动作用下建筑结构数值模拟、试验研究和理论分析的研究进展;详细综述了长持时地震动作用下建筑结构的延性性能、耗能能力、... 详细信息

该文综述了长持时地震动作用下建筑结构抗震性能的研究进展。介绍了长持时地震动的定义和特性;梳理了长持时地震动作用下建筑结构数值模拟、试验研究和理论分析的研究进展;详细综述了长持时地震动作用下建筑结构的延性性能、耗能能力、易损性和抗倒塌性能的研究进展。此外,介绍了考虑长持时地震作用影响的建筑结构抗震设计方法,梳理了国内外建筑结构抗震设计规范对长持时地震作用的考虑方法,并对长持时地震动作用下建筑结构抗震性能的研究进行了展望。建议关注长持时地震动作用下建筑结构的抗震性能,进一步研究长持时地震动的定义和特性,改进长持时地震动作用下建筑结构的数值模拟、理论分析和试验研究方法,深入探讨长持时地震动作用下各类建筑结构的地震响应、易损性和抗倒塌性能,为未来结构抗震设计及评估中考虑长持时地震作用的影响和规范修订提供参考。

关键词：防灾减灾工程及防护工程综述长持时地震动定义建筑结构抗震性能设计方法

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Evidence-practice gap analysis in the role of tick in brucellosis transmission: a scoping review

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Infectious Diseases of Poverty 2024年第1期13卷 92-92页

作者： Rui Ma Chunfu Li ai Gao Na Jiang Xinyu Feng Jian Li Wei hu School of Life Sciences Inner Mongolia University Hohhot China School of Global Health Chinese Center for Tropical Diseases Research Shanghai Jiao Tong University School of Medicine Shanghai China One Health Center Shanghai Jiao Tong University-The University of Edinburgh Shanghai China Basic Medical College Guangxi University of Chinese Medical Nanning China Department of Infectious Diseases Huashan Hospital State Key Laboratory of Genetic Engineering Ministry of Education Key Laboratory for Biodiversity Science and Ecological Engineering Ministry of Education Key Laboratory of Contemporary Anthropology School of Life Sciences Fudan University Shanghai China

Background Brucellosis is a zoonotic affiction instigated by bacteria belonging to the genus Brucella and is charac-terized by a diverse range of pervasiveness,multiple transmission routes,and serious *** is imperative to amal-gamate the current knowledge and identify gaps pertaining to the role of ticks in brucellosis *** We systematically searched China National Knowledge Infrastructure(CNKi),WanFang,Google Scholar,and PubMed on the topic published until April 23,*** procedure was performed in accordance with the Sys-tematic Reviews and Meta-Analyses extension for Scoping Reviews(PRISMA-ScR)*** selected articles were categorized across three major topic areas,and the potential data was extracted to describe evidence-practice gaps by two *** The search identifed 83 eligible studies for the final *** results highlighted the potential capacity of ticks in brucellosis transmission as evidenced by the detection of Brucella in 16 different tick *** pooled overall prevalence of Brucella in ticks was 33.87%(range:0.00-87.80%).The review also revealed the capability of Bru-cella to circulate in parasitic ticks'different developmental stages,thus posing a potential threat to animal and human *** evidence from in vitro rodent infection experiments has revealed that ticks possess the capability to transmit Brucella to uninfected animals(range:45.00-80.00%).Moreover,significant epidemiological associations have been found between the occurrence of brucellosis in animals and tick control in rangelands,which further suggests that ticks may serve as potential vectors for brucellosis transmission in ***,a mere three cases of human brucellosis resulting from potential tick bites were identified in search of global clinical case reports from 1963to *** It is imperative to improve the techniques used to identify Brucella in ticks,particularly by developing a novel,efficient,

关键词： Tick Brucella Detection human infection Risk evaluation

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