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三峡工程运行对洞庭湖湿地植被格局的影响及调控机制

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农业现代化研究 2018年第6期39卷 937-944页

作者：李峰谢永宏陈心胜邓正苗邹业爱李旭侯志勇曾静胡佳宇中国科学院亚热带农业生态研究所亚热带农业生态过程重点实验室湖南长沙410125 中国科学院洞庭湖湿地生态系统观测研究站湖南岳阳414018

湿地植被格局是湿地生态学研究的主要内容之一。湿地植被格局的变化是湿地植物生物学特性与外部环境变化共同作用的结果。洞庭湖湿地作为我国长江中下游典型通江湖泊湿地,具有重要的生态服务功能。三峡工程运行后,洞庭湖湿地水文情势变... 详细信息

湿地植被格局是湿地生态学研究的主要内容之一。湿地植被格局的变化是湿地植物生物学特性与外部环境变化共同作用的结果。洞庭湖湿地作为我国长江中下游典型通江湖泊湿地,具有重要的生态服务功能。三峡工程运行后,洞庭湖湿地水文情势变化明显,进而影响湿地植被格局。本文通过文献梳理,系统总结了三峡工程运行后洞庭湖湿地植被格局的演变规律,同时对驱动湿地植被演变的水文成因及湿地植物生物学机制进行了归纳。研究发现三峡工程运行后,洞庭湖不同植被类型面积发生明显变化,具体表现为湖草群落面积呈下降趋势,芦苇(荻)和林地群落的总面积呈上升趋势。湿地植被格局的变化是水位、淹水时间、泥沙淤积等多种水文情势综合作用的结果,而湿地植物还可以通过繁殖对策、生态生理、种内种间关系变化等多个生物学策略来适应变化的外部环境,进而维持植被格局的稳定性。最后以杨树种植和冬候鸟多样性变化为案例,分析了洞庭湖湿地植被格局变化的生态学效应,以期为洞庭湖湿地的保护及退化湿地的恢复提供一定理论依据。

关键词：洞庭湖湿地植被格局三峡工程调控机制生态学效应

High quality Sb-doped SnO2 electrodes with high oxygen evolution potential prepared by in situ hydrothermal synthesis method

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Chinese Chemical Letters 2007年第8期18卷 997-1000页

作者： ai Sheng Huang Guo Hua Zhao Hong xu li Department of Chemistry Tongji University Shanghai 200092 China

High quality Sb-doped SnO2 electrode, with high oxygen evolution potential of 3.0 V, was successfully synthesized on the Ti substrates by in situ hydrothermal synthesis method.

关键词： Metallic oxide electrode Hydrothermal synthesis Oxygen evolution reaction

Impacts of Nutlin-3a and exercise on murine double minute 2-enriched glioma treatment

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Neural Regeneration Research 2025年第4期20卷 1135-1152页

作者： Yisheng Chen Zhongcheng Fan Zhiwen Luo xueran Kang Renwen Wan Fangqi li Weiwei lin Zhihua Han Beijie Qi Jinrong lin Yaying Sun Jiebin Huang Yuzhen xu Shiyi Chen Department of Sport Medicine Huashan HospitalFudan UniversityShanghaiChina Department of Orthopedic Surgery Hainan Province Clinical Medical CenterHaikou Affiliated Hospital of Central South University Xiangya School of MedicineHaikouHainan ProvinceChina Department of Basic Medicine Shanghai Jiao Tong University School of MedicineShanghai Jiao Tong UniversityShanghaiChina Department of Neurosurgery Second Affiliated Hospital of Zhejiang University School of MedicineZhejiang UniversityHangzhouZhejiang ProvinceChina Department of Orthopedics Shanghai General HospitalSchool of Medicine Shanghai Jiao Tong UniversityShanghaiChina Department of Infectious Diseases Children’s Hospital of Fudan UniversityNational Children’s Medical CenterShanghaiChina Department of Rehabilitation The Second Affiliated Hospital of Shandong First Medical UniversityTaianShandong ProvinceChina

Recent research has demonstrated the impact of physical activity on the prognosis of glioma patients,with evidence suggesting exercise may reduce mortality risks and aid neural *** role of the small ubiquitin-like modifier(SUMO)protein,especially post-exercise,in cancer progression,is gaining attention,as are the potential anti-cancer effects of *** used machine learning to create the exercise and SUMO-related gene signature(ESLRS).This signature shows how physical activity might help improve the outlook for low-grade glioma and other *** demonstrated the prognostic and immunotherapeutic significance of ESLRS markers,specifically highlighting how murine double minute 2(MDM2),a component of the ESLRS,can be targeted by *** underscores the intricate relationship between natural compounds such as nutlin-3 and immune *** comprehensive CRISPR screening,we validated the effects of specific ESLRS genes on low-grade glioma *** also revealed insights into the effectiveness of Nutlin-3a as a potent MDM2 inhibitor through molecular docking and dynamic ***-3a inhibited glioma cell proliferation and activated the p53 *** efficacy decreased with MDM2 overexpression,and this was reversed by Nutlin-3a or *** using a low-grade glioma mouse model highlighted the effect of physical activity on oxidative stress and molecular pathway ***,both physical exercise and Nutlin-3a administration improved physical function in mice bearing tumors derived from MDM2-overexpressing *** results suggest the potential for Nutlin-3a,an MDM2 inhibitor,with physical exercise as a therapeutic approach for glioma *** research also supports the use of natural products for therapy and sheds light on the interaction of exercise,natural products,and immune regulation in cancer treatment.

关键词： exercise and SUMO-related gene signatures(ESLRS) glioblastoma management low-grade glioma natural bioactives neural regeneration physical exercise

Metabolic reprogramming: a new option for the treatment of spinal cord injury

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Neural Regeneration Research 2025年第4期20卷 1042-1057页

作者： Jiangjie Chen Jinyang Chen Chao Yu Kaishun Xia Biao Yang Ronghao Wang Yi li Kesi Shi Yuang Zhang Haibin xu xuesong Zhang Jingkai Wang Qixin Chen Chengzhen liang Department of Orthopedics The Second Affiliated Hospital of Zhejiang University School of MedicineHangzhouZhejiang ProvinceChina Orthopedics Research Institute of Zhejiang University Zhejiang UniversityHangzhouZhejiang ProvinceChina Key Laboratory of Motor System Disease Research and Precision Therapy of Zhejiang Province HangzhouZhejiang ProvinceChina Clinical Research Center of Motor System Disease of Zhejiang Province HangzhouZhejiang ProvinceChina Qiandongnan Prefecture People’s Hospital KailiGuizhou ProvinceChina Department of Orthopedics Fourth Medical CenterChinese PLA General HospitalBeijingChina

Spinal cord injuries impose a notably economic burden on society,mainly because of the severe after-effects they *** the ongoing development of various therapies for spinal cord injuries,their effectiveness remains ***,a deeper understanding of metabolism has opened up a new therapeutic opportunity in the form of metabolic *** this review,we explore the metabolic changes that occur during spinal cord injuries,their consequences,and the therapeutic tools available for metabolic *** spinal cord metabolism is characterized by independent cellular metabolism and intercellular metabolic ***,spinal cord injury results in metabolic disorders that include disturbances in glucose metabolism,lipid metabolism,and mitochondrial *** metabolic disturbances lead to corresponding pathological changes,including the failure of axonal regeneration,the accumulation of scarring,and the activation of *** rescue spinal cord injury at the metabolic level,potential metabolic reprogramming approaches have emerged,including replenishing metabolic substrates,reconstituting metabolic couplings,and targeting mitochondrial therapies to alter cell *** available evidence suggests that metabolic reprogramming holds great promise as a next-generation approach for the treatment of spinal cord *** further advance the metabolic treatment of the spinal cord injury,future efforts should focus on a deeper understanding of neurometabolism,the development of more advanced metabolomics technologies,and the design of highly effective metabolic interventions.

关键词： axons glycolysis metabolic reprogramming metabolism mitochondria neural regeneration neuroprotection oxidative phosphorylation spinal cord injury therapy

Corrosion Resistance of High Performance Weathering Steel for Bridge Building Applications

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Journal of Iron and Steel Research International 2012年第6期19卷 59-63页

作者： CHEN ai-hua xu Jian-qiu li Ran li Hua-long Institute of Research of Iron and Steel Shasteel GroupZhangjiagang 215625JiangsuChina Chief Engineering Office Shasteel GroupZhangjiagang 215625JiangsuChina

The mechanical properties, corrosion resistance and microstructures of high performance steel （HPS） was investigated by tensile testing machine, Charpy V-Notch （CVN） testing machine, cyclic immersion corrosion tester, XRD, optical microscopy （OM）, scanning electron microscopy （SEM）, and electron probe micro-analyzer （EPMA）. The results showed that significant differences existed in the tensile strength, yield strength and impact toughness between HPS and PCS. After 72 h cyclic immersion accelerated corrosion test, the inner rust layer on HPS was com- posed of a-FeOOH phase and denser than that on PCS that was a mixture of a-FeOOH and Fe3 04. The rust formed on HPS provides better protection and HPS has lower corrosion rates than PCS. Copper and chromium in HPS en- rich in the rust layer and enhance the compactness of the rust layer. Based on the results of the accelerated corrosion tests and rust layer analysis, the roles of Cu and Cr against corrosion are discussed, providing HPS with chemical specification which has been industrially successful to produce weathering steel for bridge structure.

关键词： HPS corrosion resistancel microstructure mechanical property

A hybrid organic-inorganic perovskite with robust SHG switching

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Chinese Chemical Letters 2022年第4期33卷 2143-2146页

作者： Mengjuan Yang Hao Cheng Yuqiu xu Mengzhen li Yong ai Ordered Matter Science Research Center Nanchang UniversityNanchang 330031China

Owing to the diversity of structure and potential applications in the field of electrics,sensors,and light-emitting diodes,lead halide perovskites have attracted great attention in recent *** those lead halide perovskites with non-centrosymmetric crystal structures usually exhibit nonlinear optical(NLO) characteristics,which may endow them photoelectricity switching *** this work,a lead-based hybrid organic-inorganic perovskite(HOIP) material,trimethyliodomethylammonium lead trichloride(TMIM·PbCl_(3)),is obtained on the basis of tetramethylammonium lead chloride through halogen substitution on the cation *** shows dual-phase-transition behavior around 345 and 358 K, which is significantly ***·PbCl_(3)crystallizes in the chiral space group,P2_(1)2_(1)2_(1), and shows a welldefined second harmonic generation(SHG) response,and good switching endurance,which makes it an excellent candidate for SHG switching *** work highlights the importance of halogen substitution for crystal engineering and may pave way for the further exploration of the optoelectronic devices.

关键词： Lead hybrid perovskite Second harmonic generation Single-crystal X-ray diffraction Nonlinear optical switching Halogen substitution

Effects of health concept model-based detailed behavioral care on mood and quality of life in elderly patients with chronic heart failure

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World Journal of Psychiatry 2023年第7期13卷 444-452页

作者： ai-Di Zheng li-li Cai Jing xu Department of Cardiology Affiliated Hangzhou First People’s HospitalZhejiang University School of MedicineHangzhou 310006Zhejiang ProvinceChina

BACKGROUND With the intensification of social aging,the susceptibility of the elderly population to diseases has attracted increasing attention,especially chronic heart failure(CHF)that accounts for a large proportion of the *** To evaluate the application value of health concept model-based detailed behavioral care in elderly patients with *** This study recruited 116 elderly CHF patients admitted from October 2018 to October 2020 and grouped them according to the nursing care that they *** elderly patients who underwent health concept model-based detailed behavioral care were included in a study group(SG;n=62),and those who underwent routine detailed behavioral nursing intervention were included as a control group(CG;n=54).Patients’negative emotions(NEs),quality of life(QoL),and nutritional status were assessed using the self-rating anxiety/depression scale(SAS/SDS),the Minnesota living with Heart Failure Questionnaire(MLHFQ),and the Modified Quantitative Subjective Global Assessment(MQSGA)of nutrition,*** in rehabilitation efficiency,NEs,cardiac function(CF)indexes,nutritional status,QoL,and nursing satisfaction were comparatively *** A higher response rate was recorded in the SG vs the CG after intervention(Plic dimension and left ventricular end systolic diameter were lower in the SG compared with the CG(Pailed behavioral care has high application value in the nursing care of elderly CHF patients,and it can not only effectively enhance rehabilitation efficiency,but also mitigate patients’NEs and improve their CF and QoL.

关键词： Chronic heart failure Elderly patients Health concept model Detailed behavioral care Patient mood Quality of life Nursing effect

Based on non-targeted metabolomics for differential components screening of Rosae Chinensis Flos and Rosae Rugosae Flos and their quality evaluation

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Traditional Medicine Research 2025年第2期10卷 1-15页

作者： xu liang Ni-Hui Zhang Zhi-Lai Zhan Guang-Lu Chang Yan Gao Xia li Wen-Yuan Gao School of Pharmaceutical Science and Technology Faculty of MedicineTianjin UniversityTianjin 300193China State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs China Academy of Chinese Medical SciencesBeijing 100700China Key Laboratory of Modern Chinese Medicine Resources Research Enterprises Tianjin 300402China

Background:Rosa chinensis *** Rosa rugosa *** not only of ornamental value,but also edible flowers and the flower buds have been listed in the Chinese Pharmacopoeia as traditional *** two plants have some differences in efficacy,but the flower buds are easily confused for similar *** addition,large-scale cultivation of ornamental rose flowers may lead to a decrease in the effective components of medicinal ***,it is necessary to study the chemical composition and make quality evaluation of Rosae Chinensis Flos(Yueji)and Rosae Rugosae Flos(Meigui).Methods:In this study,40 batches of samples including Meigui and Yueji from different regions in China were collected to establish high-performance liquid chromatography ***,the fingerprints data was analyzed using principal component analysis,hierarchical cluster analysis,and partial least squares discriminant analysis analysis chemometrics to obtain information on intergroup differences,and non-targeted metabolomic techniques were applied to identify and compare chemical compositions of samples which were chosen from groups with large *** compounds were screened by orthogonal partial least-squares discriminant analysis and S-plot,and finally multi-component quantification was performed to comprehensively evaluate the quality of Yueji and ***:The similarity between the fingerprints of 40 batches roses and the reference print R was 0.73 to 0.93,indicating that there were similarities and differences between the *** principal component analysis and hierarchical cluster analysis of fingerprints data,the samples from different origins and varieties were intuitively divided into four *** least-squares discriminant analysis analysis showed that Meigui and Yueji cluster into two categories and the model was reliable.A total of 89 compounds were identified by high resolution mass spectrometry,mainly were flavonoids and flavon

关键词： Rosa chinensis Jacq. Rosa rugosa Thunb. metabolomics chemometrics multiple component quantification quality evaluation

3-D CFD simulation of transients in multiple pump system with some pumps being stopped

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Journal of Hydrodynamics 2021年第3期33卷 583-592页

作者： Yue-fei liu Jian-xu Zhou Qiang Guo ai-li Shen Jian Zhang College of Water Conservancy and Hydropower Engineering Hohai UniversityNanjing210024China

The computational fluid dynamics(CFD)approach can be used to obtain both internal and external characteristics of centrifugal pumps,and the variations of the hydrodynamic force,the pressure and the torque on the blades acquired by the CFD are highly associated with the safety of the pumping *** on the CFD simulations,this paper investigates the stopping characteristics of multiple pumps with some pumps being *** 3-D geometric model is built,including all 6 pumps,the valves,the pipes,the tanks and other components,and using the Realizable k-ε turbulence *** CFD results for the operating points agree well with the results from the theoretical *** some pumps being stopped,the key parameters of the operating pumps would not be stable,with a larger fluctuation;the direction of the hydrodynamic force might be opposite with more than 3 stopped *** the stopped pumps,the maximum reverse values of the discharge and the rotational speed would be larger when fewer pumps are stopped,and could be more than 120%of the rated values,which is dangerous for the pumping *** CFD results could help understanding the stopping process of multiple pump systems with some pumps being stopped.

关键词： Centrifugal pumps some pumps stop computational fluid dynamics(CFD) operating points maximum reverse value