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Applying the Kalman filter particle method to strange and open charm hadron reconstruction in the STAR experiment

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Nuclear Science and Techniques 2023年第10期34卷 148-157页

作者： Xin-Yue Ju Yue-Hang Leung Sooraj Radhakrishnann Petr Chaloupka Xin Dong Yury Fisyak Pavol Federic Ivan Kisel hong-Wei Ke Michal Kocan Spyridon Margetis ai-hong tang Iouri Vassiliev Yi-Fei Zhang Xiang-Lei Zhu Maksym Zyzak University of Science and Technology of China Hefei 230026China Lawrence Berkeley National Laboratory BerkeleyCA 94720USA University of Heidelberg 69120 HeidelbergGermany Kent State University KentOH 44242USA Czech Technical University in Prague PragueCzech Republic Brookhaven National Laboratory UptonNY 11973USA Nuclear Physics Institute of the Czech Academy of Sciences PragueCzech Republic Goethe-Universitat Frankfurt Frankfurt am MainGermany Frankfurt Institute for Advanced Studies Frankfurt am MainGermany GSI Helmholtzzentrum für Schwerionenforschung GmbH DarmstadtGermany Tsinghua University Beijing 100084China

We applied KF Particle, a Kalman Filter package for secondary vertex finding and fitting, to strange and open charm hadron reconstruction in heavy-ion collisions in the STAR experiment. Compared to the conventional helix swimming method used in STAR, the KF Particle method considerably improved the reconstructed Λ, Ω, and D~0 significance. In addition, the Monte Carlo simulation with STAR detector responses could adequately reproduce the topological variable distributions reconstructed in real data using the KF Particle method, thereby retaining substantial control of the reconstruction efficiency uncertainties for strange and open charm hadron measurements in heavy-ion collisions.

关键词： Heavy-ion collisions Secondary vertex finding Kalman filter

Properties of the QCD matter:review of selected results from the relativistic heavy ion collider beam energy scan(RHIC BES)program

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Nuclear Science and Techniques 2024年第12期35卷 274-311页

作者： Jin‑Hui Chen Xin Dong Xiong‑hong He Huan‑Zhong Huang Feng Liu Xiao‑Feng Luo Yu‑Gang Ma Li‑Juan Ruan Ming Shao Shu‑Su Shi Xu Sun ai‑hong tang Ze‑Bo tang Fu‑Qiang Wang Hai Wang Yi Wang Zhi‑Gang Xiao Guan‑Nan Xie Nu Xu Qing‑Hua Xu Zhang‑Bu Xu Chi Yang Shuai Yang Wang‑Mei Zha Ya‑Peng Zhang Yi‑Fei Zhang Jie Zhao Xiang‑Lei Zhu Key Laboratory of Nuclear Physics and Ion‑Beam Application(MOE) Institute of Modern PhysicsFudan UniversityShanghai 200433China Nuclear Science Division Lawrence Berkeley National LaboratoryBerkeleyCA 94720USA QMRC Institute of Modern PhysicsChinese Academy of SciencesLanzhouChina Department of Physics and Astrophysics University of CaliforniaLos AngelesCA 90095USA Key Laboratory of Quark and Lepton Physics(MOE)and Institute of Particle Physics Central China Normal UniversityWuhan 430079China Department of Physics Brookhaven National LaboratoryUptonNY 11973USA Department of Modern Physics University of Science and Technology of ChinaHefeiChina Department of Physics Purdue UniversityWest LafayetteIN 47907USA Department of Engineering Physics Tsinghua UniversityBeijingChina Department of Physics Tsinghua UniversityBeijingChina School of Nuclear Science and Technology University of Chinese Academy of SciencesBeijing 100049China Key Laboratory of Particle Physics and Particle Irradiation(MOE) Institute of Frontier and Interdisciplinary ScienceShandong UniversityQingdao 266237China Department of Physics Kent State UniversityKentOH 44242USA Institute of Quantum Matter South China Normal UniversityGuangzhou 510006China

In the paper,we discuss the development of the multigap resistive plate chamber time-of-fight(TOF)technology and the production of the solenoidal tracker at RHIC(STAR)TOF detector in China at the beginning of the twenty-frst ***,recent experimental results from the frst beam energy scan program(BES-I)at the Relativistic Heavy Ion Collider(RHIC)pertaining to measurements of collectivity,chirality,criticality,global polarization,strangeness,heavy favor,dilepton and light nuclei productions are reviewed.

关键词： Heavy ion collision Quark-gluon plasma QCD phase diagram Collectivity Chirality Criticality

The interaction between KIF21A and KANK1 regulates dendritic morphology and synapse plasticity in neurons

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Neural Regeneration Research 2025年第1期20卷 209-223页

作者： Shi-Yan Sun Lingyun Nie Jing Zhang Xue Fang hongmei Luo Chuanhai Fu Zhiyi Wei ai-Hui tang Hefei National Research Center for Physical Sciences at the Microscale CAS Key Laboratory of Brain Function and DiseaseMinistry of Education Key Laboratory for Membrane-less Organelles and Cellular DynamicsDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui ProvinceChina Institute of Artificial Intelligence Hefei Comprehensive National Science CenterHefeiAnhui ProvinceChina CAS Center for Excellence in Molecular Cell Sciences Division of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui ProvinceChina Department of Neurobiology School of Life SciencesSouthern University of Science and TechnologyShenzhenGuangdong ProvinceChina Brain Research Center Southern University of Science and TechnologyShenzhenGuangdong ProvinceChina

Morphological alterations in dendritic spines have been linked to changes in functional communication between neurons that affect learning and ***-4 KIF21A helps organize the microtubule-actin network at the cell cortex by interacting with KANK1;however,whether KIF21A modulates dendritic structure and function in neurons remains *** this study,we found that KIF21A was distributed in a subset of dendritic spines,and that these KIF21A-positive spines were larger and more structurally plastic than KIF21A-negative ***,the interaction between KIF21A and KANK1 was found to be critical for dendritic spine morphogenesis and synaptic *** of either KIF21A or KANK1 inhibited dendritic spine morphogenesis and dendritic branching,and these deficits were fully rescued by coexpressing full-length KIF21A or KANK1,but not by proteins with mutations disrupting direct binding between KIF21A and KANK1 or binding between KANK1 and *** down KIF21A in the hippocampus of rats inhibited the amplitudes of long-term potentiation induced by high-frequency stimulation and negatively impacted the animals’cognitive *** together,our findings demonstrate the function of KIF21A in modulating spine morphology and provide insight into its role in synaptic function.

关键词： actin cytoskeleton dendrite KANK1 KIF21A microtubule spine morphology spine synaptic plasticity talin1

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全氟烷基膦酸锂电解液的制备与性能研究

化学学报 2008年第12期66卷 1441-1445页

作者：毕成良郭爱红唐雪娇高敏张宝贵南开大学环境科学与工程学院天津300071 河北理工大学资源与环境学院唐山063009

选取氯代二异丙基膦(C6H14PCl)为原料,利用电化学氟化方法,得到全氟烷基膦酸[(C3F7)2PF3],(C3F7)2PF3与氟化锂(LiF)反应得到全氟烷基膦酸锂(Li[(C3F7)2PF4]),将其溶于碳酸乙烯酯(EC)和碳酸二甲酯(DMC)质量比为1∶1的混合溶剂中得到电解... 详细信息

选取氯代二异丙基膦(C6H14PCl)为原料,利用电化学氟化方法,得到全氟烷基膦酸[(C3F7)2PF3],(C3F7)2PF3与氟化锂(LiF)反应得到全氟烷基膦酸锂(Li[(C3F7)2PF4]),将其溶于碳酸乙烯酯(EC)和碳酸二甲酯(DMC)质量比为1∶1的混合溶剂中得到电解液,考察电解液的电导率、抗水性及氧化分解电位.以LiCoO2为正极,锂片为负极组装两电极模拟电池体系,测试得到电池的放电平台为3.7V;电池的首次放电比容量为107mA.h.g-1;当循环放电40次后,容量衰减较快,电池循环50周后,效率仍保持102%.交流阻抗图谱表明电解液放电时的阻抗约为140..研究结果表明,全氟烷基膦酸锂有望成为新型锂离子二次电池的电解质盐.

关键词：电化学氟化锂离子二次电池全氟烷基膦酸锂

Prevalence of Helicobacter pylori infection in Chinese military personnel:A cross-sectional,multicenter-based study

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World Journal of Gastroenterology 2025年第3期31卷 42-49页

作者： Han-Chen Min Chun-Yan Zhang Fang-Yu Wang Xiao-Hui Yu Shan-hong tang hong-Wu Zhu Ya-Gang Zhao Ji-Luo Liu Jian Wang Jing-Han Guo Xiao-Mei Zhang Yun-Sheng Yang Chinese People’s Liberation Army Medical School Chinese People’s Liberation Army General HospitalBeijing 100853China Department of Gastroenterology and Hepatology The First Medical CenterChinese People’s Liberation Army General HospitalBeijing 100853China Sixth Healthcare Department The Second Medical CenterChinese People’s Liberation Army General HospitalBeijing 100853China Department of Gastroenterology The 940th Hospital of Joint Logistic Support Force of Chinese People’s Liberation ArmyLanzhou 730050Gansu ProvinceChina Department of Gastroenterology General Hospital of Western Theater CommandChengdu 610011Sichuan ProvinceChina Department of Gastroenterology General Hospital of Southern Theater CommandGuangzhou 510010Guangdong ProvinceChina Department of Epidemiology Naval Medical UniversityShanghai 200433China School of Medicine Nankai UniversityTianjin 300071China National Clinical Research Center for Geriatric Diseases Chinese People’s Liberation Army General HospitalBeijing 100853China

BACKGROUND Helicobacter pylori(***)infection is a prevalent disease encountered in military internal medicine and recognized as the main cause of dyspepsia,gastritis,and peptic ulcer,which are common diseases in military *** guidelines in China state all patients with evidence of active infection with *** are offered ***,the prevalence of *** infection and its regional distribution in the military population remain unclear,which hinders effective prevention and treatment *** the prevalence of *** infection in the military population will aid in the development of customized strategies to better manage this infectious *** To investigate the prevalence of *** infection in the Chinese military population in different geographic *** This multicenter,retrospective study included 22421 individuals from five tertiary hospitals located in north,east,southwest,and northwest cities of *** infection was identified using the urea breath test,which had been performed between January 2020 and December *** Of the 22421 military service members,7416(33.1%)were urea breath *** highest prevalence of *** was in the 30-39 years age group for military personnel,with an infection rate of 34.9%.The majority of infected subjects were younger than 40-years-old,accounting for 70.4%of the infected *** individuals serviced in Lanzhou and Chengdu showed a higher infection prevalence than those in Beijing,Nanjing,and Guangzhou,with prevalence rates of 44.3%,37.9%,29.0%,31.1%,and 32.3%,*** *** infection remains a common infectious disease among military personnel in China and has a relatively high prevalence rate in northwest China.

关键词： Helicobacter pylori Prevalence Military personnel Urea breath test Multicenter study

Aquaporin-4-IgG-seropositive neuromyelitis optica spectrum disorders:progress of experimental models based on disease pathogenesis

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Neural Regeneration Research 2025年第2期20卷 354-365页

作者： Li Xu Huiming Xu Changyong tang Department of Neurology The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhouGuangdong ProvinceChina

Neuromyelitis optica spectrum disorders are neuroinflammatory demyelinating disorders that lead to permanent visual loss and motor *** date,no effective treatment exists as the exact causative mechanism remains ***,experimental models of neuromyelitis optica spectrum disorders are essential for exploring its pathogenesis and in screening for therapeutic *** most patients with neuromyelitis optica spectrum disorders are seropositive for IgG autoantibodies against aquaporin-4,which is highly expressed on the membrane of astrocyte endfeet,most current experimental models are based on aquaporin-4-IgG that initially targets *** experimental models have successfully simulated many pathological features of neuromyelitis optica spectrum disorders,such as aquaporin-4 loss,astrocytopathy,granulocyte and macrophage infiltration,complement activation,demyelination,and neuronal loss;however,they do not fully capture the pathological process of human neuromyelitis optica spectrum *** this review,we summarize the currently known pathogenic mechanisms and the development of associated experimental models in vitro,ex vivo,and in vivo for neuromyelitis optica spectrum disorders,suggest potential pathogenic mechanisms for further investigation,and provide guidance on experimental model *** addition,this review summarizes the latest information on pathologies and therapies for neuromyelitis optica spectrum disorders based on experimental models of aquaporin-4-IgG-seropositive neuromyelitis optica spectrum disorders,offering further therapeutic targets and a theoretical basis for clinical trials.

关键词： aquaporin-4 experimental model neuromyelitis optica spectrum disorder pathogenesis

Soluble epoxide hydrolase:a next-generation drug target for Alzheimer's disease and related dementias

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Neural Regeneration Research 2025年第9期20卷 2585-2586页

作者： Andrew Gregory Chengyun tang Fan Fan Department of Physiology Medical College of GeorgiaAugusta UniversityAugustaGAUSA

Alzheimer's disease(AD)and Alzheimer's diseaserelated dementias(ADRD)represent a significant public health challenge,with projections indicating a substantial increase in affected individuals due to the aging global *** the World Health Organization,AD/ADRD has affected more than 55 million individuals worldwide,with an additional 10 million cases diagnosed each year.

关键词： Alzheimer population drug

Unraveling the mechanism of action of Shangxia Liangji formula for treating insomnia:a metabolomics and network pharmacology approach

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Traditional Medicine Research 2025年第2期10卷 16-29页

作者： Xia-Jie Quan Hao Liang Yong-hong tang Li Jiang Xiong-Ying Ji Feng-Ying Zhang Ping Zhang Bo Ouyang Department of Information The Affiliated Nanhua HospitalHengyang Medical SchoolUniversity of South ChinaHengyang 421002China Department of Neurology The Affiliated Nanhua HospitalHengyang Medical SchoolUniversity of South ChinaHengyang 421002China Department of Gastroscopy The Affiliated Nanhua HospitalHengyang Medical SchoolUniversity of South ChinaHengyang 421002China Department of Traditional Chinese Medicine The Affiliated Nanhua HospitalHengyang Medical SchoolUniversity of South ChinaHengyang 421002China

Background:Insomnia is a prevalent clinical condition and Shangxia Liangji formula(SXLJF)is a well-established method of ***,the specific mechanism of action of SXLJF remains ***:The mouse model of insomnia was established by intraperitoneal injection of ***-two mice were randomly divided into a negative control group,model group,SXLJF group(18.72 g/kg/day),and positive control group(diazepam,2 mg/kg)and treated with the corresponding drugs for 7 consecutive *** open field test and pentobarbital-induced sleeping test were ***-MS-based untargeted metabolomics and network pharmacology were applied to explore the potential targets of SXLJF for treating ***,key targets were validated using ***:Behavioral tests demonstrated that SXLJF reduced the total distance,average velocity,central distance,and sleep latency,and prolonged sleep *** and network pharmacology revealed potential targets,signaling pathways,metabolic pathways,and metabolites associated with the anti-insomnia effects of ***,tyrosine hydroxylase(TH)and tyrosine metabolism emerged as crucial metabolic pathways and targets,***-qPCR results supported the role of TH in the mechanism of SXLJF in treating ***:In conclusion,TH and tyrosine metabolism may represent significant targets and pathways for SXLJF in treating insomnia.

关键词： Shangxia Liangji formula insomnia metabolomics network pharmacology tyrosine hydroxylase tyrosine metabolism

Cell polarization in ischemic stroke: molecular mechanisms and advances

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Neural Regeneration Research 2025年第3期20卷 632-645页

作者： Yuanwei Li Xiaoxiao Xu Xuan Wu Jiarui Li Shiling Chen Danyang Chen Gaigai Li Zhouping tang Department of Neurology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina

Ischemic stroke is a cerebrovascular disease associated with high mortality and disability rates. Since the inflammation and immune response play a central role in driving ischemic damage, it becomes essential to modulate excessive inflammatory reactions to promote cell survival and facilitate tissue repair around the injury site. Various cell types are involved in the inflammatory response, including microglia, astrocytes, and neutrophils, each exhibiting distinct phenotypic profiles upon stimulation. They display either proinflammatory or anti-inflammatory states, a phenomenon known as ‘cell polarization.’ There are two cell polarization therapy strategies. The first involves inducing cells into a neuroprotective phenotype in vitro, then reintroducing them autologously. The second approach utilizes small molecular substances to directly affect cells in vivo. In this review, we elucidate the polarization dynamics of the three reactive cell populations(microglia, astrocytes, and neutrophils) in the context of ischemic stroke, and provide a comprehensive summary of the molecular mechanisms involved in their phenotypic switching. By unraveling the complexity of cell polarization, we hope to offer insights for future research on neuroinflammation and novel therapeutic strategies for ischemic stroke.

关键词： astrocyte polarization immune regulation inflammation ischemic injury microglia polarization neutrophil polarization signaling pathways stroke