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Endoscopic retrograde cholangiopancreatography guided interventions in the management of pancreatic cancer

World Journal of Gastrointestinal Endoscopy 2020年第10期12卷 323-340页

作者： Muhammad Nadeem Yousaf Hamid Ehsan ahsan wahab Ahmad Muneeb Fizah S Chaudhary Richard Williams Christopher J Haas Department of Medicine Medstar Union Memorial HospitalBaltimoreMD 21218United States Department of Medicine MedStar Good Samaritan HospitalBaltimoreMD 21239United States Department of Medicine Medstar Franklin Square Medical CenterBaltimoreMD 21237United States Department of Medicine MedStar Harbor HospitalBaltimoreMD 21225United States Department of Hospital Medicine Baptist Medical Center SouthMontgomeryAL 36116United States Department of Medicine Faisalabad Medical UniversityFaisalabald 38000PunjabPakistan

Pancreatic cancer is the leading cause of cancer-related morbidity and mortality with an overall five-year survival of less than 9%in the United *** presentation,the majority of patients have painless jaundice,pruritis,and malaise,a triad that develops secondary to obstruction,which often occurs late in the course of the disease *** technical advancements in radiological imaging and endoscopic interventions have played a crucial role in the diagnosis,staging,and management of patients with pancreatic *** retrograde cholangiopancreatography(ERCP)-guided diagnosis(with brush cytology,serial pancreatic juice aspiration cytologic examination technique,or biliary biopsy)and therapeutic interventions such as pancreatobiliary decompression,intraductal and relief of gastric outlet obstruction play a pivotal role in the management of advanced pancreatic cancer and are increasingly used due to improved morbidity and complication rates compared to surgical *** this review,we highlight various ERCP-guided diagnostic and therapeutic interventions for the management of pancreatic cancer.

关键词： Pancreatic cancer Endoscopic retrograde cholangiopancreatography Malignant stricture Biliary drainage Biliary stent Gastric outlet obstruction

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