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The USP7 protein interaction network and its roles in tumorigenesis

Genes & Diseases 2022年第1期9卷 41-50页

作者： ahood al-eidan Yihua Wang Paul Skipp Rob M.Ewing School of Biological Sciences B85 Life SciencesUniversity of SouthamptonSouthamptonSO171BJUK Department of Biology College of SciencesImam Abdulrahman Bin Faisal UniversityP.O.Box 1982DammamSaudi Arabia

Ubiquitin-specific protease(USP7),also known as Herpesvirus-associated ubiquitin-specific protease(HAUSP),is a *** has been significant recent attention on USP7 following the discovery that USP7 is a key regulator of the p53-MDM2 *** USP7 protein is 130 kDa in size and has multiple domains which bind to a diverse set of *** interactions mediate key developmental and homeostatic processes including the cell cycle,immune response,and modulation of transcription factor and epigenetic regulator activity and ***7 also promotes carcinogenesis through aberrant activation of the Wnt signalling pathway and stabilization of HIF-1α.These findings have shown that USP7 may induce tumour progression and be a therapeutic *** with interest in developing USP7 as a target,several studies have defined new protein interactions and the regulatory networks within which USP7 *** this review,we focus on the protein interactions of USP7 that are most important for its cancer-associated roles.

关键词： Cancer Deubiquitinase Protein network Protein-protein interaction Proteomics USP7

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Preventing Phishing Attack on Voting System Using Visual Cryptography

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Journal of Computer and Communications 2022年第10期10卷 149-161页

作者： ahood alotaibi Lama alhubaidi alghala alyami Leena Marghalani Bashayer alharbi Naya Nagy College of Cybersecurity and Digital Forensics Imam Abdulrahman Bin Faisal University Dammam Saudi Arabia College of Computer Science and Information Technology Imam Abdulrahman Bin Faisal University Dammam Saudi Arabia

Phishing is one of the most common social engineering attacks that users over the internet fall for. An example is voting systems, and because such systems should be accurate and error free, phishing prevention techniques are crucial. Visual Cryptography (VC) is utilized for efficient voting system authentication to cast votes. VC is one of the most secure approaches for privacy protection as it ensures the confidentiality of the voting system. This paper discusses proposed phishing prevention methods and compares different proposed methods.

关键词： Remote Voting System (RVS) Voting System (VS) Shares Ballots Authentication Visual Cryptography Phishing Captcha

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