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Practical approach to linear endoscopic ultrasound examination of the gallbladder

World Journal of Radiology 2024年第6期16卷 184-195页

作者： Hussein Hassan Okasha Eyad Gadour Hassan Atalla Omar AbdAllah AbdEl-Hameed Reem Ezzat ahmed elsayed alzamzamy elsayed Ghoneem Rasha Ahmad Matar Zeinab Hassan Bogdan Miutescu Ayman Qawasmi Katarzyna M Pawlak ahmed Elmeligui Department of Internal Medicine Division of Gastroenterology and HepatologyKasr Al-Aini School of MedicineCairo UniversityCairo 11562Egypt Department of Gastroenterology and Hepatology King Abdulaziz Hospital-National GuardAhsa 31982Saudi Arabia Department of Medicine School of MedicineZamzam University CollegeKhartoum 11113Sudan Department of Internal Medicine Hepatology and Gastroenterology UnitFaculty of MedicineMansoura UniversityMansoura 35516Egypt Department of Internal Medicine Faculty of MedicineAssiut UniversityAssiut 71511Egypt Department of Gastroenterology and Heptology Maadi Armed Forces Medical ComplexMilitary Medical AcademyCairo 11728Egypt Department of Gastroenterology and Advance Endoscopy Sultant Qaboos Comprehensive Cancer Care and Research CentreMuscat 0961Oman Department of Internal Medicine Stockport Hospitals NHS Foundation TrustManchester SK27JEUnited Kingdom Department of Gastroenterology and Hepatology Victor Babes University of Medicine and PharmacyTimisoara 300041Romania Advanced Regional Research Centre in Gastroenterology and Hepatology Victor Babes University of Medicine and PharmacyTimisoara 30041Romania Department of Gastroenterology Al-Makassed Islamic Charitable Society HospitalCairo 11124Egypt Division of Gastroenterology St.Michael’s HospitalUniversity of TorontoToronto M5B 1W8Canada Department of Gastroenterology Southend University HospitalEssex SS26XTUnited Kingdom

The gallbladder(GB)is a susceptible organ,prone to various pathologies that can be identified using different imaging *** ultrasound(TUS)is typically the initial diagnostic method due to its numerous well-established ***,in cases of uncertainty or when a definitive diagnosis cannot be established,computed tomography(CT)or magnetic resonance imaging may be employed to provide more detailed ***,CT scans may sometimes offer inadequate spatial resolution,which can limit the differentiation of GB lesions,particularly when smaller yet clinically relevant abnormalities are ***,endoscopic ultrasound(EUS)provides higher frequency compared to TUS,superior spatial resolution,and the option for contrast-enhanced harmonic imaging,enabling a more comprehensive ***,EUS can serve as a supplementary tool when conventional imaging methods are *** review will describe the standard EUS examination of the GB,focusing on its endosonographic characteristics in various GB path-ologies.

关键词： Endoscopic ultrasound Linear endoscopic ultrasound Gallbladder anatomy Gallbladder pathologies Therapeutic endoscopic ultrasound

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Cronkhite-Canada syndrome:First case report from Egypt and North Africa

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World Journal of Gastrointestinal Endoscopy 2022年第10期14卷 642-647页

作者： ahmed elsayed alzamzamy Ashraf Aboubakr Hussein H Okasha Abeer Abdellatef Shaimaa Elkholy Mahmoudd Wahba Mohamed Alboraie Hussein elsayed Mohamed O Othman Department of Gastroenterology and Hepatology Maadi Armed Forces Medical ComplexMilitary Medical AcademyCairo 11711Egypt Department of Internal Medicine Division of GastroenterologyHepatology and EndoscopyCairo UniversityCairo 11311Egypt Department of Internal Medicine Al-Azhar UniversityCairo 11311Egypt Department of Pathology Military Medical AcademyCairo 11711Egypt Department of Internal Medicine Baylor College of MedicineHoustonTX 77082United States

BACKGROUND Gastrointestinal(GI)polyposis is a rare condition in GI *** date about 500 cases of Cronkhite-Canada syndrome(CCS)have been reported *** SUMMARY We report a 60-year-old female patient who presented with dyspepsia,abdominal pain,and weight loss of 1-year *** physical examination showed alopecia and *** endoscopy revealed diffuse markedly thickened gastric mucosa involving the whole stomach with thickened gastric rugae and numerous polypoidal *** examination showed marked hyperplasia of the foveolar glands with inflammatory cell *** ultrasound showed a significantly hypertrophic mucosa and muscularis mucosa,while the submucosa and the muscularis propria were spared,favouring its benign *** showed multiple sessile polyps scattered at different parts of the *** examination revealed tubular adenomatous polyps with low-grade *** diagnoses included CCS,Menterier disease(MD),other polyposis syndromes,lymphoma,amyloidosis,and gastric *** presence of alopecia,nail dystrophy,GI polyposis,markedly thickened gastric mucosa and folds,abdominal pain,weight loss,and marked foveolar gland hyperplasia;all was in favour of *** was excluded due to sparing of the muscularis *** presence of colonic polyps and antral and duodenal infiltration,and the absence of hypoproteinaemia decreased the possibility for *** The patient was diagnosed as having CCS.

关键词： Gastrointestinal polyposis Thickened gastric mucosa Cronkhite-Canada syndrome Case report

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Flavone improves liver damage in nicotine-exposed rats via the Nrf2/HO-1 pathway

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Asian Pacific Journal of Tropical Biomedicine 2024年第8期14卷 341-349页

作者： Nora A.elsayed Fatma SM Moawed Esraa SA ahmed ahmed Hammad Omayma AR Abo-Zaid Biochemistry and Molecular Biology Department Faculty of Vet.Med.Benha UniversityBenha cityEgypt Health Radiation Research National Center for Radiation Research and TechnologyEgyptian Atomic Energy AuthorityCairoEgypt Radiation Biology Department National Center for Radiation Research and TechnologyEgyptian Atomic Energy AuthorityCairoEgypt

Objective:To assess the hepatoprotective effects of flavone on nicotine-induced liver ***:Thirty-six rats were allocated into six groups:the control group,the nicotine group,the flavone alone groups(10 and 25 mg/kg/body weight),and the nicotine groups treated with flavone(10 and 25 mg/kg/body weight).Liver function,oxidative stress,Nrf2 pathway(HO-1,Nrf2,and Keap-1),and inflammatory markers(IL-17,TNF-α,and NF-κB)were ***,a histopathological examination of liver tissues was ***:Nicotine increased liver damage,inflammation,and oxidative ***,flavone suppressed nicotine-induced liver enzymes,oxidative stress,and inflammation,as manifested by increased antioxidants and decreased malondialdehyde level,liver enzymatic activities,and inflammatory ***(10 and 25 mg/kg/body weight)also reduced the level of Keap-1 and increased HO-1 and Nrf2 levels in the liver of nicotine-exposed ***:Flavone has hepatoprotective properties and may slow the progression of liver injury by reducing oxidative stress,liver enzymes,and inflammation possibly via the Nrf2 pathway.

关键词： Flavone Nicotine Liver Nrf2 HO-1 NF-κB

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Impact of auditory stimulation nursing protocol on auditory response in cerebrovascular stroke patients

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Journal of Integrative Nursing 2024年第2期6卷 111-116页

作者： Mohammed elsayed ZAKY Hanan ahmed AL SEBAEE Nagat El Morsy IBRAHIEM Heba ahmed MOHAMMED Mohammad Edrees MOHAMMAD Department of Medical Surgical Nursing Faculty of NursingCairo UniversityCairoEgypt Department of Neurology Faculty of MedicineCairo UniversityCairoEgypt

Objectives:The objective of the study was to explore the impact of auditory stimulation protocol on auditory response in cerebrovascular stroke(CVS)*** and Methods:A pre-posttest nonequivalent control group quasi-experimental study was conducted at Al Mainal Hospital at Al Kars Einy Hospital,Cairo University,among 60 CVS patients,and the sample was randomly assigned through a coin to allocate subjects to study or control group(30 for each group).Auditory stimulation techniques were applied three times per week for the study group for two consecutive *** in the control group received only routine hospital care during the study *** Glasgow Coma Scale(GCS)score for assessing the neurological function and level of arousal and the auditory subscale score of Western Neuro Sensory Stimulation Profile(WNSSP)for assessing auditory response were recorded and compared between the two groups before and after the ***:There were statistically significant differences between the study group and the control group regarding third reading of GCS score(11.5±0.3 vs.10.6±0.9,t=4.676,P=0.000).The scores of all auditory subscales of WNSSP in the study groups increased after implementing the auditory stimulation protocol(P<0.05).Conclusion:Utilizing the auditory stimulation protocol by nurse proves to be an effective method for enhancing hearing responses in individuals with CVS.

关键词： Auditory stimulation techniques hearing response nursing management stroke

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A new technique of monsplasty as an adjunctive procedure in cases of abdominoplasty:A prospective clinical trial

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Chinese Journal of Plastic and Reconstructive Surgery 2024年第3期6卷 124-129页

作者： Laila ahmed Aboul Nasr Sherief Zamer ahmed Fathy elsayed Mohamed Hatem Elsahar Department of Plastic Surgery Faculty of Medicine Kasr Al-AinyCairo UniversityCairo11562Egypt

Background:No standard monsplasty technique has existed until *** various monsplasty methods have been described,they exhibit high complication rates with sparse postoperative *** that used pubic suspension techniques did not describe exact anatomical landmarks for the mons *** study aimed to improve the aesthetic and functional appearance of the pubic region with long-term results for all grades of pubic ptosis or bulging with abdominoplasty and provide exact anatomical points to anchor the mons to the rectus ***:This non-randomized prospective clinical trial included 30 patients with various degrees of abdominal wall laxity between December 2017 and September *** surgical procedure was performed for female patients with pendulous abdomen,pubic ptosis or bulging,body mass index≤35 kg/m^(2),and age 18–60 *** patients were followed for up to one year;patient satisfaction was assessed before and after surgery regarding aesthetic results and impact on outfits,hygiene,and sexual ***:The marginal homogeneity test revealed a statistically significant patient satisfaction rate regarding outfits,sexual function,hygiene,and *** postoperative complications,seroma(one case)was managed by aspiration,and one case of wound dehiscence was managed conservatively with ***:This study recommends a quick and reproducible monsplasty technique with a low complication rate,a technique that helps determine specific anatomical landmarks for anchoring the mons to the rectus *** this technique with abdominal contouring is advisable for optimal aesthetic results and maintained lymphatic drainage in the pubic region.

关键词： Abdominoplasty Mons ptosis Pubic suspension Skin redundancy

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An Improved Enterprise Resource Planning System Using Machine Learning Techniques

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Journal of Software Engineering and Applications 2024年第5期17卷 203-213页

作者： ahmed Youssri Zakaria elsayed Abdelbadea Atef Raslan Tarek Ali Mervat Gheith Al-Sayed Khater Essam A. Amin Department of Software Engineering Faculty of Graduate Studies for Statistical Research (FGSSR) Cairo University Giza Egypt

Traditional Enterprise Resource Planning (ERP) systems with relational databases take weeks to deliver predictable insights instantly. The most accurate information is provided to companies to make the best decisions through advanced analytics that examine the past and the future and capture information about the present. Integrating machine learning (ML) into financial ERP systems offers several benefits, including increased accuracy, efficiency, and cost savings. Also, ERP systems are crucial in overseeing different aspects of Human Capital Management (HCM) in organizations. The performance of the staff draws the interest of the management. In particular, to guarantee that the proper employees are assigned to the convenient task at the suitable moment, train and qualify them, and build evaluation systems to follow up their performance and an attempt to maintain the potential talents of workers. Also, predicting employee salaries correctly is necessary for the efficient distribution of resources, retaining talent, and ensuring the success of the organization as a whole. Conventional ERP system salary forecasting methods typically use static reports that only show the system’s current state, without analyzing employee data or providing recommendations. We designed and enforced a prototype to define to apply ML algorithms on Oracle EBS data to enhance employee evaluation using real-time data directly from the ERP system. Based on measurements of accuracy, the Random Forest algorithm enhanced the performance of this system. This model offers an accuracy of 90% on the balanced dataset.

关键词： ERP HCM Machine Learning Employee Performance Pythonista Pythoneer

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Serum vascular endothelial growth factor as a tumor marker for hepatocellular carcinoma in hepatitis C virus-related cirrhotic patients

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World Journal of Gastrointestinal Oncology 2021年第6期13卷 600-611页

作者： ahmed alzamzamy Huda elsayed Mona Abd Elraouf Hanan Eltoukhy Tarek Megahed Ashraf Aboubakr Department of Gastroenterology and Hepatology Military Medical AcademyCairo 11841Egypt Department of Gastroenterology and Hepatology Maadi Armed Forces Medical ComplexCairo 11841Egypt Department of Internal Medicine Faculty of Medicine for GirlsAl-Azhar UniversityCairo 11311Egypt Department of Clinical Pathology Military Medical AcademyCairo 11311Egypt

BACKGROUND Hepatocellular carcinoma(HCC)accounts for 8.2%of all cancer-related deaths *** a vascular tumor,vascular endothelial growth factor(VEGF)plays a vital role in HCC pathogenesis,growth,and *** To determine the accuracy of serum VEGF and VEGF/platelet(PLT)as tumor markers in the early detection of HCC cases in patients with hepatitis C virus(HCV)-related liver *** We conducted a case-control study with HCV patients from the outpatient and inpatient hepatology *** were classified into three groups:(1)HCC group;(2)Cirrhosis group;and(3)HCV without cirrhosis(control group).Patients were clinically evaluated,and blood samples were drawn for the analysis;serum VEGF levels were measured by a specific VEGF human recombinant enzyme-linked immunosorbent assay *** from the three study groups were compared by the one-way analysis of variance or Kruskal-Wallis *** operating characteristic curves were constructed to determine the optimal cut-off values of alpha fetoprotein(AFP),VEGF,and VEGF/PLT that provided the best diagnostic *** sensitivity and specificity at the optimal cut-off value of each biomarker were then *** This study included one hundred patients(HCC,cirrhosis,and control groups:n=40,30,30,respectively).HCC patients had significantly higher serum VEGF and VEGF/PLT levels than the non-HCC groups(P=0.001).Serum VEGF and VEGF/PLT showed significant positive correlations with and HCC tumor size,stage,vascular invasion,and Child-Pugh ***,a VEGF cut-off the value of 250 pg/mL provided 80%sensitivity and 81.7%specificity for discriminating HCC patient from non-HCC ***,the ratio of VEGF/PLT provided sensitivity and specificity of 77.5%and 80%,respectively which is higher than the accuracy provided by *** combination of AFP,VEGF,and VEGF/PLT increases the accuracy of diagnosing HCC to>95%.CONCLUSION In HCV patients,serum VEGF and VEGF/PLT separ

关键词： Hepatocellular carcinoma Vascular endothelial growth factor Biomarkers Diagnosis

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Evaluation of hypolipidemic Marrubium vulgare effect in Triton WR-1339-induced hyperlipidemia in mice

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Asian Pacific Journal of Tropical Medicine 2016年第5期9卷 439-445页

作者： Abeer Y Ibrahim Saber F Hendawy ahmed A A elsayed elsayed A Omer Medicinal and Aromatic Plants Researches Dept. Pharmaceutical and Drug Industries Division National Research Centre

Objective: To evaluate the hypocholesterolemic and hypotriglyceridemic activities of four Marrbium vulgare(M. vulgare) herb extracts using Triton WR-1339-induced hyperlipidemia in mice. Methods: Hyperlipidemia was developed by intraperitoneal injection of Triton(200 mg/kg body weight). The animals were divided into main four groups of eight mice each: normal control group, hyperlipidemic control group, hyperlipidemic plus tween-40 control and treated group. The fourth one was divided into four subgroups, petroleum ether extract group, chloroform extract group, ethyl acetate extract group and methanol extract treated group each of them contains two sub-sub group for treating animals with two doses at 0.1 and 0.25 LD50. Results: After 7 h and 24 h of treatment, the intragastric administration of all extracts caused a significant decrease of plasma total cholesterol. Triglyceride levels were also significantly lowered by all extracts while petroleum ether produced the lowest decreasing level. Similar results were observed for LDL-cholesterol concentrations. Furthermore, more polar extracts(methanol and ethyl acetate)-soluble fractions showed a significant ameliorative action on elevated atherogenic index(AI) and LDL/HDL-C ratios, while these atherogenic markers were not statistically suppressed by the chloroform and petroleum ether-soluble extract. Conclusion: The findings indicated that Marrubium may contain polar products able to lower plasma lipid concentrations and might be beneficial in treatment of hyperlipidemia and atherosclerosis.

关键词： Anti-hyperlipidemia Marrubium vulgare Triton Antioxidant Atherogenic index

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Physical properties of three short period close binaries:KIC 2715417,KIC 6050116 and KIC 6287172

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Research in Astronomy and Astrophysics 2019年第2期19卷 111-124页

作者： Mahmoud AbdelFattah NegmEldin ahmed Essam elsayed Shahinaz Mostafa Yousef Astronomy Space Science and Meteorology Department Faculty of Science Cairo University Department of Astronomy National Research Institute of Astronomy and Geophysics(Egypt)

We present the physical parameters of three short period close binaries using data observed from the Kepler Space Telescope. All of these observations were taken in a single bandpass(which approximates the Johnson V-band). Our three systems are KIC 2715417, KIC 6050116 and KIC 6287172. The first system, KIC 2715417, is considered a semi-detached system with the secondary component filling its Roche lobe. The second system, KIC 6050116, is an overcontact system, while the third system, KIC 6287172, belongs to ellipsoidal variables as deduced from the Roche lobe geometry. For photometric analysis, we used the PHOEBE software package, which is based on the Wilson-Devinney code. Due to lack of spectroscopic data, the photometric mass ratios are determined from the analyses of light curves using the q-search method. The absolute parameters are determined using three different methods(Harmanec, Maceroni &Van'tVeer and Gazeas & Niarchos).

关键词： stars:binaries:eclipsing stars:fundamental parameters stars:luminosity function,mass function stars:individual(KIC 2715417,KIC 6050116 and KIC 6287172)

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Multi-Task Learning Model with Data Augmentation for Arabic Aspect-Based Sentiment Analysis

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Computers, Materials & Continua 2023年第5期75卷 4419-4444页

作者： Arwa Saif Fadel Osama ahmed Abulnaja Mostafa elsayed Saleh Department of Computer Science Faculty of Computing and Information TechnologyKing Abdulaziz UniversityJeddah21589Saudi Arabia Department of Computer Science Faculty of Computer Sciences and EngineeringHodeidah UniversityYemen

Aspect-based sentiment analysis(ABSA)is a fine-grained *** fundamental subtasks are aspect termextraction(ATE)and aspect polarity classification(APC),and these subtasks are dependent and closely ***,most existing works on Arabic ABSA content separately address them,assume that aspect terms are preidentified,or use a pipeline *** solutions design different models for each task,and the output from the ATE model is used as the input to the APC model,which may result in error propagation among different steps because APC is affected by ATE *** methods are impractical for real-world scenarios where the ATE task is the base task for APC,and its result impacts the accuracy of ***,in this study,we focused on a multi-task learning model for Arabic ATE and APC in which the model is jointly trained on two subtasks simultaneously in a *** paper integrates themulti-task model,namely Local Cotext Foucse-Aspect Term Extraction and Polarity classification(LCF-ATEPC)and Arabic Bidirectional Encoder Representation from Transformers(AraBERT)as a shred layer for Arabic contextual text *** LCF-ATEPC model is based on a multi-head selfattention and local context focus mechanism(LCF)to capture the interactive information between an aspect and its ***,data augmentation techniques are proposed based on state-of-the-art augmentation techniques(word embedding substitution with constraints and contextual embedding(AraBERT))to increase the diversity of the training *** paper examined the effect of data augmentation on the multi-task model for Arabic *** experiments were conducted on the original and combined datasets(merging the original and augmented datasets).Experimental results demonstrate that the proposed Multi-task model outperformed existing APC *** results were obtained by AraBERT and LCF-ATEPC with fusion layer(AR-LCF-ATEPC-Fusion)and the proposed data augmentation

关键词： Arabic aspect extraction arabic sentiment classification AraBERT multi-task learning data augmentation

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