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A new distributed feature selection technique for classifying gene expression data

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International Journal of Biomathematics 2019年第4期12卷 79-109页

作者： Sarah m.Ayyad ahmed I.saleh Labib m.Labib Computers and Systems Department Faculty of Engineering Mansoura University Mansoura 35511 Egypt

Classification of gene expression data is a pivotal research area that plays a substantial role in diagnosis and prediction of diseases. Generally, feature selection is one of the extensively used techniques in data mining approaches, especially in classification. Gene expression data are usually composed of dozens of samples characterized by thousands of genes. This increases the dimensionality coupled with the existence of irrelevant and redundant features. Accordingly, the selection of informative genes (features) becomes difficult, which badly affects the gene classification accuracy. In this paper, we consider the feature selection for classifying gene expression microarray datasets. The goal is to detect the most possibly cancer-related genes in a distributed manner, which helps in effectively classifying the samples. Initially, the available huge amount of considered features are subdivided and distributed among several processors. Then, a new filter selection method based on a fuzzy inference system is applied to each subset of the dataset. Finally, all the resulted features are ranked, then a wrapper-based selection method is applied. Experimental results showed that our proposed feature selection technique performs better than other techniques since it produces lower time latency and improves classification performance.

关键词： Feature selection gene expression dimensionality reduction microarray data classification distributed learning mathematics Subject Classification

Thermochemical Aspects of Activated Ammonium Perchlorates with Superior Thermal Stability,Decomposition Enthalpy,Propagation Index,and Decomposition Kinetic Parameters

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Journal of Thermal Science 2021年第6期30卷 2196-2201页

作者： SHERIF Elbasuney m.Yehia SHUKRI Ismael SHERIF Farag ahmed saleh GHARIEB S.El-Sayyad Head of Nanotechnology Research Center Military Technical College(MTC)Cairo 11646Egypt School of Chemical Engineering Military Technical College(MTC)Cairo 11646Egypt Science and Technology Center of Excellence Cairo 11646Egypt Drug Radiation Research Department National Center for Radiation Research and Technology(NCRRT)Egyptian Atomic Energy Authority(EAEA)Cairo 11646Egypt

Ammonium perchlorate(AP)includes oxidizing and reducing elements on the same *** can act as an efficient oxidizer and mono-propellant as *** this study,AP experienced crystallographic phase change from orthorhombic centrosymmetric to non-centrosymmetric under controlled isothermal heat *** diffractograms confirmed this crystallographic phase *** thermal behaviour of activated AP had been investigated using *** AP demonstrated high chemical stability with an increase in endothermic phase transition enthalpy by 170%.The enthalpy of the subsequent two main exothermic decomposition reactions was increased by 250%.Whereas AP demonstrated total decomposition enthalpy of 733 J/g,activated AP showed 2614 J/*** AP can secure self-sustained response at a high *** index(combustion enthalpy/ignition temperature)was employed to assess self-sustained reaction *** AP demonstrated high propagation index of 8.7 compared with 2.5 for un-activated *** decomposition kinetic parameters had investigated using Kissinger and KAS *** AP showed an increase in activation energy by 89%using the Kissinger method;kinetic parameters using the KAS method were in good agreement with the Kissinger *** can have concluded that AP with novel kinetic decomposition parameters for enhanced safety storage and high combustion characteristics has evolved.

关键词： solid propellants oxidizers thermal behavior Kinetic parameters activation energy

Combinatory effect of hesperetin and mesenchymal stem cells on the deteriorated lipid profile,heart and kidney functions and antioxidant activity in STZ-induced diabetic rats

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BIOCELL 2020年第1期44卷 27-39页

作者： Osama m.ahmed mohamed A.HASSAN Ablaa S.saleh Experimental Obesity and Diabetes Research Lab(EODRL) Physiology DivisionZoology DepartmentFaculty of ScienceBeni-Suef UniversityPO 62521Beni-SuefEgypt Biochemistry Department Faculty of ScienceBeni-Suef UniversityPO 62521Beni-SuefEgypt

This study aimed to assess the effect of hesperetin and/or bone marrow-derived mesenchymal stem cells(Bm-mSCs)on disturbed lipid profile,heart and kidney functions,oxidative stress and antioxidant defense system in streptozotocin(STZ)-induced diabetic *** 1 diabetes mellitus(T1Dm)was induced in male Wistar rats by injecting 40 mg/kg body weight(b.w.)STZ dissolved in citrate buffer(pH 4.5).The diabetic rats were treated with hesperetin orally administered at dose 20 mg/kg b.w.,Bm-mSCs intravenously injected at a dose of 1 x 106 cells/rat/week and their combination for 6 *** diabetic rats exhibited lipid abnormalities manifested by elevated serum levels of total cholesterol,triglycerides,LDL-cholesterol and VLDL-cholesterol and lowered HDL-cholesterol as well as elevated liver cholesterol and triglycerides content in association with the resultant fasting and postprandial hyperglycemia and insulin *** heart function biomarkers including CK-mB,AST and LDH activities as well as levels of kidney function parameters,creatinine,and urea,were significantly raised in the serum of diabetic *** changes were concomitant with abnormal redox balance represented by elevated lipid peroxidation,decreased glutathione content,and suppressed antioxidant enzyme activities in both heart and kidney of diabetic *** previous deleterious alterations were significantly ameliorated after the treatment of diabetic rats with hesperetin and Bm-mSCs singly or in combination;the treatment with hesperetin together with Bm-mSCs was the most *** on these findings,it can be concluded that the use of hesperetin with Bm-mSCs may have more additive therapeutic value than their uses singly in *** addition,the ameliorative effects of hesperetin and Bm-mSCs on lipid profile and heart and kidney functions in diabetic rats may be mediated,at least in part,via their suppressive effects on oxidative stress and ameliorative effects on the antioxidant defense system

关键词： Bm-mSCs Hesperetin Streptozotocin-induced diabetes

Awareness and knowledge about glaucoma among patients visiting the screening clinic in Jeddah Eye Hospital,Saudi Arabia

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International Journal of Ophthalmology(English edition) 2021年第6期14卷 887-895页

作者： saleh m.Alqahtani marwan A Bakarman ahmed Almanjoumi Sami H.Alzahrani ministry of Health Jeddah 23545Saudi Arabia Department of Family and Community medicine Faculty of Medicine in RabighKing Abdul Aziz UniversityJeddah 21589Saudi Arabia Ophthalmology Department Faculty of MedicineKing Abdulaziz UniversityJeddah 22234Saudi Arabia Family medicine Department Faculty of MedicineKing Abdulaziz UniversityJeddah 22431Saudi Arabia

AIm:To explore levels and determinants of awareness and knowledge about glaucoma among ***:This was a cross-sectional study that included adult patients from October to the end of December 2018.A semi-structured questionnaire was designed by the researchers to measure the levels of awareness and knowledge about 18 basic information about *** sheet was divided into 4 domains:types of glaucoma,risk factors,clinical features,and management.A knowledge score(KS,range=0-18)was calculated,with higher scores indicating higher ***:A total of 383 patients responded to the questionnaire,61.9%males,mean±SD age was 38.5±12.94 years old,and 61.6%had a university degree or *** them,6.3%and 23.2%reported personal and family history of glaucoma,*** most frequently reported source of information about glaucoma was another person with glaucoma(28.2%),followed by physicians(24.8%)and TV(19.6%).Knowledge by item ranged from 3.1%to 82.5%correctness rate,while KS showed mean=5.91 and median=5;and reliability testing of the knowledge scale showed Cronbach’s alpha=*** KS were found among respondents with higher educational level(P=0.036),diabetes history(P=0.025),and personal(Pmily(Pma among the attendees of a local eye care hospital,where several misconceptions about disease risk factors,clinical features,and management are identified.

关键词： awareness knowledge glaucoma Saudi Arabia

Plant phenolic extracts for the quality protection of frying oil during deep frying:Sources,effects,and mechanisms

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Grain & Oil Science and Technology 2023年第3期6卷 148-161页

作者： Fa Wang Yixi Sun Shanshan Li Jing Yan Wen Qin ahmed S.m.saleh Qing Zhang College of Food Science Sichuan Agricultural UniversityYa'anSichuanChina Key Laboratory of Agricultural Product Processing and Nutrition and Health of the ministry of Agriculture and Rural Affairs(Jointly Built by the ministry and the Province) Ya'anSichuanChina Department of Food Science and Technology Faculty of AgricultureAssiut UniversityEgypt

Protection of frying oil from deterioration by adding plant phenolic extracts to guarantee the quality of fried foods becomes the primary approach to promote the sustainable development of deep ***,sources,antioxidant effects,and mechanisms of plant phenolic extracts recently applied in the quality protection of frying oil as well as challenges for the actual use of these extracts are comprehensively reviewed in this ***,herbs,berries,tea leaves,and fruit and vegetable wastes are common sources for preparing phenolic extracts showing comparative antioxidant capacity referring to the synthetic *** general effect of using these natural antioxidants is the improvement of thermal stability to extend the shelf life of frying oil and thus the modification of edible quality of fried ***,the increases in common quality attributes and amount of hazardous products and the oxidative reduction of unsaturated triacylglycerols without negatively influencing the sensory quality are inhibited when suitable plant extracts are *** incorporation of plant phenolic extracts other than synthetic counterparts in frying oil has been demonstrated as a potential method to improve the frying performance of ***,challenges for the scale application of plant phenolic extracts,such as the purity,thermal stability,and antioxidant timing,are still needed to be further investigated.

关键词： Frying oil Phenolic antioxidants Plant extract Physicochemical properties Antioxidant mechanisms

Automatic Channel Detection Using DNN on 2D Seismic Data

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Computer Systems Science & Engineering 2021年第1期36卷 57-67页

作者： Fahd A.Alhaidari saleh A.Al-Dossary Ilyas A.Salih Abdlrhman m.Salem ahmed S.Bokir mahmoud O.Fares mohammed I.ahmed mohammed S.ahmed Imam Abdulrahman Bin Faisal University College of Computer Science and Information TechnologyDammam34212Saudi Arabia Saudi Aramco Oil Company EXPEC-IIDhahranSaudi Arabia

Geologists interpret seismic data to understand subsurface properties and subsequently to locate underground hydrocarbon *** are among the most important geological features interpreters analyze to locate petroleum ***,manual channel picking is both time consuming and ***,similar to any other process dependent on human intervention,manual channel picking is error prone and *** address these issues,automatic channel detection is both necessary and important for efficient and accurate seismic *** systems make use of real-time image processing techniques for different *** channel detection is a combination of different mathematical methods in digital image processing that can identify streaks within the images called channels that are important to the oil *** this paper,we propose an innovative automatic channel detection algorithm based on machine learning *** new algorithm can identify channels in seismic data/images fully automatically and tremendously increases the efficiency and accuracy of the interpretation *** algorithm uses deep neural network to train the classifier with both the channel and non-channel *** provide a field data example to demonstrate the performance of the new *** training phase gave a maximum accuracy of 84.6%for the classifier and it performed even better in the testing phase,giving a maximum accuracy of 90%.

关键词： Deep neural networks deep learning channel detection image processing two-dimensional seismic data

Assessment of Water Resources in Sana’a Region,Yemen Republic（Case Study）

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Assessment of Water Resources in Sana’a Region,Yemen Republ...

作者： Aljawzi，Alhasan ahmed saleh Hussein 扬州大学

学位级别：硕士

一、概述也门共和国位于干旱和半干旱地区,这从降雨量的缺乏及其数量和分布的不规则性中可以明显看出。它被认为是遭受水资源短缺的十个国家之一,同时,由于缺乏未来的战略计划,该国是中东水资源最枯竭的国家之一。也门存在的不合理使用... 详细信息

一、概述也门共和国位于干旱和半干旱地区,这从降雨量的缺乏及其数量和分布的不规则性中可以明显看出。它被认为是遭受水资源短缺的十个国家之一,同时,由于缺乏未来的战略计划,该国是中东水资源最枯竭的国家之一。也门存在的不合理使用可用水资源的问题已导致地下水迅速枯竭。农业生产消耗了可用水资源总量的约93%,没有哪个国家的地下含水层枯竭速度像也门一样快。由于该国的政治冲突,数百万也门人无法获得清洁的饮用水,大多数农民失去了农业活动。相关报告显示,超过45%的公共结构处于倒塌状态缺乏满足其需求的资源。城市地区依靠地下水来满足用水需求,而农村地区则依靠水井和小型水坝和池塘等传统的集水方法。早期的研究表明也门可再生地下水15亿m3（1.5 Bm3）,地表水10亿m3（1.0 Bm3）,需水量34亿m3（3.4 Bm3）。相比之下,可再生水量为2.5 Bm3,这意味着有0.9 Bm3的赤字需要通过地下水来补偿。最近,由于当前的需水量达到3.9 Bm3（2020年）,这一缺口已增加到约1.4 Bm3,到2025年将增加到4.4 Bm3。早期的研究表明,也门的可再生水资源从1980年到1997年分别从246m3/人/年减少到130m3/人/年。2018年可再生水资源为73.69 m3/人/年。另一方面,也门水与环境部表明,2019年可再生水资源为85 m3/人/年;到2025年和2026年,这将达到66 m3/人/年。没有准确的统计数据表达人均年用水量,但大约在70-85m3/人/年的范围内。这一下降幅度相当大,表明也门的人均用水量与其他国家相比不超过10%。在中东和北非,可再生水资源平均约为1050-1500 m3/人/年,全球达到7500-8300 m3/人/年。有时水是由妇女从远方带来的,这可能使她们在社会多元化的社会中处于危险之中。萨那（Sana’a）地区是本研究的研究区域,被认为是也门最缺水的地区之一。它受到对国家产生负面或正面影响的因素的影响。因此,鉴于目前的水资源状况,研究人员预计未来几年会发生干旱。随着人口的增加和地下水补给方案的缺乏,自2000年开挖深度达到100多m以来,地下水位持续下降,而2020年,研究区域内部分地区深度达到1000多m。萨那地区的水供应量取决于家庭住地位置和收入比例。最近人口的快速增长增加了农业部门的用水量（尤其是Qat植物种植）,而降雨不足导致地下水的过度使用。由于该地区的气候,研究区域的农作物受到限制,温度在影响作物寿命加快速度方面起着重要作用,也影响作物产量。萨那盆地抽取的地下水量约为补给量的400%,因此研究区大部分地下水井因地下水位下降而干涸,估计每年下降6-8m。缺水人口的增加对国家的经济、社会和政治构成了重大挑战,并威胁到环境的稳定。尽管萨那地区缺水,但也存在雨水排放问题,尤其是在首都。由于人口拥挤和城市扩张,附近的山谷降雨径流流入萨那市中心（阿尔赛拉河道）。此外,萨那地区的内部移民在也门城市中排名第一,城市人口占萨那市总人口的比例已达到7.52%。也门的水危机,特别是在萨那地区,是一个随着时间的推移变得越来越严重的重大问题。政府没有令人满意的解决方案,尤其是该国目前发生的政治冲突事件,这些问题需要对水资源进行最新的综合评估研究。研究区的水资源状况非常危急,必须优先考虑能缓解危机并在未来追求水可持续发展的研究和计划。因此,本研究旨在评估萨那地区的水资源,包括地表水和地下水,以及它们的数量和分布、供水和各种用水需求。本研究的重要性在于作为一项重要的综合研究,它将评估和突出该地区水资源的现状,鼓励决策者实现该地区的可持续发展目标。在此基础上,可以通过一项计划,在萨那地区,尤其是整个也门,实现第六个可持续发展目标,以便到2030年,政府寻求实现人人平等获得安全和负担得起的饮用水目标,并实现其它目标,例如提高所有部门的用水效率,实施各级水资源综合管理,以及与世界各国类似的其他目标。通过这项研究,将了解研究区的水状况,并与以前的情况进行比较,了解政府制定的计划和方案的受益程度、有效性以及阻碍其实施的原因。本研究的具体目标是:该研究的目的是评估萨那的水资源。为实现该研究目标,设定了以下研究内容:○ 了解研究区域当前的水资源状况并确定最紧迫的水资源问题。○ 尽可能充分地利用水资源的措施。○ 了解缺水对人口的影响。○ 提出解决水相关问题的解决方案和建议。二、研究技术方法1)研究区特征萨那地区位于也门中北部,海拔2300米,纬度14° 450～16° 50,经度43°300～45° 50。它由两个主要地区组成,即萨那省和萨那市,萨那省从四面包围着萨那市。萨那市也被称为Amanat Alasimah,是也门的政治和历史首都,全区总面积12259 km2,其中萨那省11869 km2,萨那市390 km2。根据联合国

关键词：萨那地区降雨雨量站地表水地下水水危机 (污水)处理厂 Arc Hydro程序

HCV Therapy Follow-up Fractionation (CTF2) by Intra-PBmC Nested RNA PCR Recognizes Early Virologic Response and Relapse

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Journal of Clinical and Translational Hepatology 2018年第2期6卷 147-154页

作者： mohamed Darwish ahmed Abd Alla saleh ahmed Elibiary Ramy Hassan Elshaboury George Y.Wu Reham m.Dawood mostafa Kamel El Awady Tropical medicine Department Faculty of MedicineAl-Azhar UniversityCairoEgypt Department of Pharmacy Massachusetts General HospitalBostonMAUSA Department of medicine Division of Gastroenterology-HepatologyUniversity of Connecticut Health CenterHartfordCTUSA Department of microbial Biotechnology National Research CenterCairoEgypt

Background and Aims:Sustained virologic response is evaluated by single-step reverse transcription(SRT)PCR as-say,which assesses hepatitis C virus(HCV)clearance from plasma but not from tissues such as peripheral blood mono-nuclear cells(PBmCs).Persistence of HCV RNA in PBmCs beyond end of treatment(EOT)is associated with *** goal was to measure intra-PBmC HCV RNA levels during oral antiviral therapy according to the HCV therapy follow-up fractionation(CTF2)***:Compen-sated chronic HCV patients(n=278 SRT-PCR positive)were scheduled to receive oral antiviral *** were followed-up by SRT and intra-PBmCs HCV RNA PCR at the end of the 2nd,6th,10th,14th,18th and 24th weeks to evaluate virus clearance from plasma and PBmCs,*** CTF2 protocol evaluated SRT and PBmC PCR status at each follow-up point for determining therapy continuation or inter-ruption to address cost ***:All patients tested negative by SRT PCR after therapy for 2 ***-cation of the CTF2 protocol revealed:a)increasing HCV clear-ance rate from 75.9%at the end of 10th week to 90.3%at the end of 24th week(pm plasma compared to PBmCs at each point of follow-up until the 18th week(pmination rates diagnosed by PBmC HCV RNA PCR(?)compared to PBmC HCV RNA PCR(+)from the 6th to 24th week of treatment(pme increase curve of combined plasma and PBmC HCV RNA determined negativity compared to the decline in positivity curves by PBmC PCR at the 6th-18th week compared to the 24th week(pment continuation;and e)solitary evaluation of EOT sustained HCV infection and relapses by PBmC HCV RNA(pmination of serum and tissue(PBmC)HCV infection by oral antiviral therapy can be achieved and evaluated during a cost-effective CTF2 pro-tocol application.

关键词： CTF2 protocol HCV PBmCs PCR Cost-effectiveness

Neurocysticercosis:A case report and brief review

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Asian Pacific Journal of Tropical medicine 2016年第1期9卷 98-100页

作者： Syed A.A.Rizvi Ayman m.saleh Hanns Frimpong Hussain m.Al mohiy Jasmin ahmed Ronda D.Edwards Sultan S.ahmed College of Pharmacy Nora Southeastern University JAS medical management LLC Department of Basic medical Sciences College of MedicineKing Saud Bin Abdulaziz University for Health SciencesNational Guard Health Affairs Radiological Sciences Department College of Applied Medical SciencesKing Khalid University Herbert Wertheim College of medicine Florida International University School of medicine Spartan Health Science University

Neurocysticercosis(NCC) is one of the seven neglected endemic zoonoses targeted by the World Health *** is considered a common infection of the nervous system caused by the Tanenia solium and is known to be the primary cause of preventable epilepsy in many developing *** is commonly resulted by the ingestion of Tanenia solium eggs after consuming undercooked pork,or contaminated *** parasite can grow in the brain and spinal cord within the nervous system,causing severe headache and seizures beside other pathological *** and international travel to endemic countries has made this disease common in the United *** can be diagnosed with computed tomography and magnetic resonance imaging of the *** treatment of the NCC including cysticidal drugs(eg.,albendazole and praziquantel),and neurosurgical procedure,depending upon a the situation.A patient of Asian origin came to our clinic with complaints of dizziness,headaches and episodes seizures for the past twelve years without proper *** computed tomography and magnetic resonance imaging scans indicated multilobulated cystic mass in the brain with the suspicion of neurocysticercosis.

关键词： Neurocysticercosis Tanenia solium Epilepsy magnetic resonance imaging Computed Tomography