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Phytochemical Constituents and Allelopathic Effects of Some Medicinal Plants Extract on the Soil Algal Diversity

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Journal of Agricultural Science and Technology(A) 2013年第12期3卷 1000-1009页

作者： Mustafa ahmed fawzy AwatiefFahmey Hifney ahmed Abdel-Salam Issa Gamal Gareib Botany & Microbiology Department Faculty of Science Assiut University Assiut 71516 Egypt

Phytochemical constituents of the shoots and roots extract of chosen eight medicinal plants （Plantago major, Verbesina encelioides, Glinus lotoides, Helotropium supinum, Mentha microphylla, Euphorbia hirta, Juncus subulatus and Convolvulus arvensis） were estimated using standard qualitative analysis. The extract contained alkaloids, glycosides, saponins, phenols, tannins, f[avonoids and terpenoids in some medicinal plants while others contain some only of these phytochemical components. Allelopathic effect of the various concentrations of the extracts on the soil algal diversity was also investigated. Wollea saccata was the only algal species disappeared from all applied investigated plant extracts. Phormidium richardsii, Monoraphidium braunii, Eunotia verneris and Nitzschia bilobata were the highly sensitive algal species to all applied shoot and root extract from all tested plants, they disappeared from most of the studied plants. On the other hand, Phormidium animale and Chlorella neustonice were highly tolerant algal species to all applied extracts. Counts of Cyanophyceae, Chlorophyceae and Bacillariophyceae were decreased by addition of some investigated medicinal plants extracts such as Juncus subulatus, Convolvulus arvensis and Euphorbia hirta. So the authors can use these plants extracts in biocontrol of the nuisance of algal bloom or any other microorganisms. Also, these plants may be useful to recover eutrophic water which needs further investigation.

关键词： Allelopathy allelochemicals Plantago major Verbesina encelioides Glinus lotoides Phormidium richardsii,Monoraphidium braunii.

Polymeric biomaterial hydrogels. I. Behavior of some ionotropic cross-linked metal-alginate hydrogels especially copper-alginate membranes in some organic solvents and buffer solutions

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Advances in Bioscience and Biotechnology 2012年第7期3卷 845-854页

作者： Refat Hassan Fahd Tirkistani Ishaq Zaafarany ahmed fawzy Mohamed Khairy Sayed Iqbal Chemistry Department Faculty of Applied Sciences Umm Al-Qura University Makkah KSA Chemistry Department Faculty of Science Assiut University Assiut Egypt Chemistry Department Faculty of Science Benha University Benha Egypt Chemistry Department Saifia College of Science and Education Bhopal India

The change in rheological and mechanical properties for some ionotropic cross-linked metal-alginate hydrogel complexes in particularly copper-alginate membranes in the presence of some organic solvents (benzene, toluene, xylene, carbon tetrachloride, ace-tone, chloroform, dichloroethane, isobutyl alcohol and ethyl alcohol) or buffer solutions (acetates, borates and universal buffers) have been investigated. The experimental results showed a remarkable tendency of the studied hydrogels for shrinking in polar solvents, whereas no influence was observed for the hydrogels in non-polar solvents. On the other hand, the gels were found to swell or shrink in the buffer solutions depending on the pH of the buffer used. The swelling extent for hydrogel spheres was found to decrease in the order Cu > Ba ≈ Ca > Zn > Pb-alginates in universal buffers of pH = 5.33. The factors affected this behavior have been examined and discussed.

关键词： Biomaterials Hydrogels Swelling Shrinking Metal-Alginates Biocatalysts

Performance Analysis on a Dual External Cavity Tunable Laser ECTL Source

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Journal of Electromagnetic Analysis and Applications 2015年第4期7卷 134-139页

作者： ahmed fawzy Osama M. El-Ghandour Hesham F. A. Hamed Department of Electrical Engineering Minia University Minia Egypt Department of Electronics Communications and Computer Engineering Helwan University Cairo Egypt

This paper presents the diffraction effects on the performance of a dual external cavity tunable laser source, whose external cavities are constructed by micro electro mechanical systems (MEMS). One of the main problems in these structures is the optical diffraction as the emitting surface of the laser diode is usually quite limited in the transverse directions. The emitted beam diffracts rapidly in the air and only a small amount of light is coupled back to the source that usually limits the tuning range of the source. Device characteristics such as tuning range, wavelength shift and sensitivity are evaluated. New expression is used and multiple reflections inside external cavities are considered. The simulation results have shown that single external cavity has limited tuning range. It is shown that multiple reflections have significant effect in our model. To get a better engineering for the dual ECTL dimensions, diffraction effects must be taken into account.

关键词： External Cavity Laser Tunable Laser MEMS Optical Diffraction

A Comparative Kinetic Study on the Efficacious Permanganate Oxidation of Fluorenes in Perchloric and Sulfuric Acid Media

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Open Journal of Physical Chemistry 2017年第2期7卷 35-49页

作者： Rabab S. Jassas ahmed fawzy Rami J. Obied Mohammed A. S. Abourehab Saleh A. ahmed Chemistry Department Faculty of Applied Science Umm Al-Qura University Makkah Saudi Arabia Chemistry Department Faculty of Science Assiut University Assiut Egypt Department of Pharmaceutics Faculty of Pharmacy Umm Al-Qura University Makkah Saudi Arabia Department of Pharmaceutics and Industrial Pharmacy Faculty of Pharmacy Minia University Minia Egypt

Oxidation kinetics of fluorene (Fl) and its halogenated derivatives, namely, 2,7-dichlorofluorene (Fl-Cl), 2,7-dibromofluorene (Fl-Br) and 2,7-diiodofluorene (Fl-I), by permanganate ion in both perchloric and sulfuric acid media have been investigated using conventional spectrophotometric technique. In both acidic media, the reactions manifested first order kineticsin [permanganate] and less than unit order each in [reductants] and [acid]. Increasing ionic strength had no effect on the oxidation rates. Oxidation rates of fluorenes in perchloric acid were higher than those in sulfuric acid and the order of the oxidation rates was: Fl > Fl-I > Fl-Br > Fl-Cl. Final oxidation products were identified by GC/MS and FT-IR analyses in all cases as 9H-fluorenone derivatives. Reaction constants as well as activation parameters of the second order rate constants were also evaluated.

关键词： Oxidation Kinetics Mechanism Fluorenes Permanganate

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The Genetic Variant c.553G>T in the Lipoprotein A5 Effects on Lipid Profile Parameters Levels

作者： (埃及)艾哈迈德·法齐·迦得(ahmed fawzy Gad)

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World Journal of Cardiovascular Diseases 2019年第2期9卷 122-131页

作者： Neda M. Bogari Ashwag Aljohani Amr A. Amin Faisal A. Al-Allaf Anas Dannoun Mohiuddin M. Taher Atalla Elsayed Dareen Ibrahim Rednah Osama Elkhatee Massimo Porqueddu Francesco Alamanni ahmed fawzy Medical Genetics Department Faculty of Medicine Umm Al-Qura University Makkah KSA Biochemistry Department Faculty of Medicine Umm Al-Qura University Makkah KSA Faculty of Medicine Ain Shams University Cairo Egypt Science and Technology Unit Umm Al-Qura University Makkah KSA St James’s Hospital Dublin UK Occupational Medicine The University of Manchester Manchester UK Fakeeh Hospital Jeddah KSA Department of Cardiology Dalhousie University Halifax Nova Scotia Canada Department of Cardiac Surgery King Fahd Armed Forces Hospital Jeddah KSA Department of Cardiac Surgery Monzino Heart Center University of Milan Milan Italy Division of Human Genetics and Genome Research Department of Molecular Genetics and human Enzymology National Research Centre Giza Egypt

Abnormal levels of plasma lipid have been linked to atherosclerosis, strokes and heart conditions. Variations in high-density lipoprotein (HDL) and low-density lipoprotein (LDL) cholesterol levels are considered as risk factors for coronary artery disease (CAD). Furthermore, triglycerides are a leading cause of cardiovascular disease. Therefore, measurement of plasma lipid levels is an important mortality predictor. Several factors were associated with irregularity in plasma lipids such as genetic alterations. Recent researches have linked single nucleotides polymorphism (SNP) in ApoA5 gene with these deviations. In this study, we reported the effects of the genetic variant c.553G>T in ApoA5 on the levels of plasma lipids. To explore these effects, a case-control study including 280 male and female subjects (44 of them were assigned as CAD cases while the remaining subjects were categorized as control) was established. All patients in the study were recruited from the western region in KSA. The results have detected minor variations in LDL, HDL and cholesterol levels between CAD patients carrying T allele and CAD patients carrying the WT allele. However, there were no significant effects due to these variations. TG levels in the wild type carriers reached up to 291 mg/dl while T allele carriers, the cases, presented lower levels of TG (170 mg/dl and 71 mg/dl). Although, T allele showed no effects on plasma lipids with the exception of TG levels. We suggest by this study that T allele in this SNP might be considered as a valuable tool in the diagnosis of CAD.

关键词： APOA5 Gene Polymorphism Genetic Variation Coronary Artery Disease Kingdom of Saudi Arabia (KSA)

Whole Exome Sequencing: Novel Genetic Polymorphisms in Saudi Arabian Attention Deficit Hyperactivity Disorder (ADHD) Children

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Natural Science 2019年第2期11卷 45-60页

作者： Neda Mostafa Bogari Amr ahmed Amin Ashwag Aljohani Ghida Dairi Mahmoud Zaki El-Readi Anas Dannoun Udaya Raja Mohammad Adil Nermeen Qutub Suhair Alhelfawi Amal Alobaidi Derar Alqudah Hussain Banni Safaa Yehia Eid Huda Balto Faisal Al-Allaf Mohiuddin Taher Hiba Saed Al-Amoodi ahmed fawzy Department of Medical Genetics Faculty of Medicine Umm Al-Qura University Makkah KSA Biochemistry Department Faculty of Medicine Umm Al-Qura University Makkah KSA Faculty of Medicine Ain Shams University Cairo Egypt Umm Al-Qura University Makkah KSA Biochemistry Department Faculty of Pharmacy Al-Azhar University Assuit Egypt Integrated Gulf Biosystems Jeddah KSA Special Needs Department School of Education Umm Al-Qura University Mecca KSA Sinad City for Special Needs Makkah KSA Institute of Education University of Reading Reading UK Faculty of Medicine King Abdulaziz University Jeddah KSA Science and Technology Unit Umm Al-Qura University Makkah KSA Division of Human Genetics & Genome Researches Department of Molecular Genetics and Enzymology National Research Centre Dokki Egypt

Background: Attention-deficit hyperactivity disorder (ADHD) is a widespread and debilitating disorder with relatively high prevalence in Saudi Arabia. Neuropsychological and radiological investigations have revealed that there are some differences in the components of the brain regions in children with and without ADHD. In this study we have performed whole exome sequencing (WES) in four non-familial cases of ADHD from Makkah Region to identify the genetic polymorphisms associated with the disease in our Saudi population. Methods: Exome sequencing was carried out using Ion Proton with AmpliSeq Exome library methods, and the data were analysed by Ion Reporter 5.6 software. Results: A total of 33 variants were identified from 222 genes selected from the GWAS catalogue for ADHD associated genes. However, the SNPs we identified in these genes were not reported to be associated with ADHD in previous studies. We have identified 2 novel missense variants;one in c.3451G > T;p. (Ala1151Ser) in ITGA1 gene and another is c.988G > A;p. (Ala330Thr) in SPATA13 genes. The variants rs928661, rs11150370 and rs386792899 were the only three variants that appeared on all the 4 patients studied. Six missense variants, rs16841277, rs2228209, rs2230283, rs3741883, rs1716 and rs2272606, were found in 3 different patients, respectively. However, the three documented variants are rs13166360 with bipolar disorder, rs920829 with neuropathic pain, and rs6558702 with schizophrenia. Conclusion: We have identified 2 novel variants in ADHD children. SIFT score of all variants indicates that these substitutions have damaging effects on the protein function. Further screening studies are recommended for confirmation.

关键词： Next Generation DNA Sequencing Single Nucleotide Polymorphisms Saudi Children Attention-Deficit Hyperactivity Disorder ADHD

Polymeric biomaterial hydrogels. I. Behavior of some ionotropic cross-linked metal-alginate hydrogels especially copper-alginate membranes in some organic solvents and buffer solutions

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A Comparative Analysis on Surgical Outcomes and Complications of Endoscopic and Open Vein Harvesting Techniques

Advances in Bioscience and Biotechnology（生命科学与技术进展） 2012年第7期

作者： Refat Hassan Fahd Tirkistani Ishaq Zaafarany ahmed fawzy Mohamed Khairy Sayed Iqbal

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Open Journal of Thoracic Surgery 2024年第2期14卷 29-39页

作者： Mohammed fawzy Eltaweel Ismail N. El-Sokkary ahmed Alherazi Mohamed Wael Badawi Mohammed G. Abdellatif Bahaa A. Elkhonezy Ibrahim K. Gamil Haytham Mohamed Abd El Moaty Sarra Sadmi Mahmoud Khalil Department of Cardiothoracic Surgery Faculty of Medicine Menoufia University Shibin El Kom Egypt Department of Cardiovascular & Thoracic Surgery Faculty of Medicine Al-Azhar University Cairo Egypt Department of Cardiothoracic Surgery Faculty of Medicine Alexandria University Alexandria Egypt Faculty of Medicine University of Algiers Algiers Algeria Department of Cardiac Surgery Sabah Al-Ahmed Cardiac Center Al-Amiri Hospital Kuwait City Kuwait

Objective: The great saphenous vein (GSV) is commonly used as a conduit for grafting during CABG surgery, and open GSV harvesting (OVH), commonly used with long incision to expose the vein. However, endoscopic vein harvesting (EVH) is an alternative approach, utilizing specialized instruments and small incisions to harvest the vein. Methods: A retrospective analysis was conducted on a cohort of patients who underwent Coronary artery bypass graft (CABG) requiring great saphenous vein (GSV) harvesting which was done by EVH or OVH procedures. Demographic variables, including age and gender, were assessed for both groups. Intraoperative variables such as the number of grafts, cardiopulmonary bypass time, X clamp time, and type of procedure were analyzed. Postoperative variables, including infection and bleeding rates, were also evaluated. Results: The study included 30 patients each undergoing Coronary artery bypass graft (CABG) with need of great saphenous vein harvesting which was done by EVH and OVH. Demographic variables were well-matched between the two groups in terms of age, while a significant difference in gender distribution was observed. Obesity and smoking were more prevalent in the OVH group, and EVH was associated with a higher mean number of grafts compared to OVH. Conversion to an open technique occurred in a portion of the EVH cases, and infection rates did not significantly differ between the EVH and OVH groups. However, the incidence of postoperative bleeding was significantly higher in the EVH group. Conclusion: This study provides valuable insights into the demographic, intraoperative, and postoperative variables associated with EVH and OVH techniques. EVH demonstrated advantages in terms of reduced infection rates compared to OVH. However, the higher incidence of postoperative bleeding associated with EVH raises concerns about potential risks.

关键词： Endoscopic Vein Harvesting (EVH) Open Vein Harvesting (OVH) Coronary Artery Bypass Grafting (CABG) Great Saphenous Vein (GSV) Surgical Outcomes