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Extended Forgery Detection Framework for COVID-19 Medical Data Using Convolutional Neural Network

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Computers, Materials & Continua 2021年第9期68卷 3773-3787页

作者： Sajid Habib Gill Noor ahmed Sheikh Samina Rajpar Zain ul Abidin N.Z.Jhanjhi Muneer Ahmad Mirza Abdur Razzaq Sultan S.Alshamrani Yasir malik Fehmi Jaafar Department of Computer Science Shah Abdul Latif UniversityKhairpur66020SindhPakistan National College of Business Administration&Economics Lahore54000Pakistan School of Computer Science and Engineering SCETaylor’s UniversityMalaysia Department of Information Systems Faculty of Computer Science&Information TechnologyUniversiti MalayaMalaysia Department of Information Technology College of Computer and Information TechnologyTaif UniversityTaif21944Saudi Arabia Department of Computer Science College of Engineering&Computing SciencesNew York Institute of TechnologyVancouverCanada The Computer Research Institute of Montreal QuebecCanada

Medical data tampering has become one of the main challenges in the field of secure-aware medical data *** of normal patients’medical data to present them as COVID-19 patients is an illegitimate action that has been carried out in different ways ***,the integrity of these data can be *** detection is a method of detecting an anomaly in manipulated forged *** appropriate number of features are needed to identify an anomaly as either forged or non-forged data in order to find distortion or tampering in the original *** neural networks(CNNs)have contributed a major breakthrough in this type of *** has been much interest from both the clinicians and the AI community in the possibility of widespread usage of artificial neural networks for quick diagnosis using medical data for early COVID-19 patient *** purpose of this paper is to detect forgery in COVID-19 medical data by using CNN in the error level analysis(ELA)by verifying the noise pattern in the *** proposed improved ELA method is evaluated using a type of data splicing forgery and sigmoid and ReLU phenomenon *** proposed method is verified by manipulating COVID-19 data using different types of forgeries and then applying the proposed CNN model to the data to detect the data *** results show that the accuracy of the proposed CNN model on the test COVID-19 data is approximately 92%.

关键词： Data security data privacy medical-data forgery COVID-19 convolutional neural network machine learning deep learning

Spin quantum well-like behavior in single-crystal Gd0.75La0.25FeO3

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Science China Materials 2021年第2期64卷 531-536页

作者： Xin Wen Zhigang Song Iftikhar ahmed malik Yifei Fang Wenyun Yang Jingzhi Han Shunquan Liu Honglin Du Shixun Cao Jinxing Zhang Xiangqun Zhang Zhaohua Cheng Yanglong Hou Jinbo Yang State Key Laboratory for Mesoscopic Physics and School of Physics Peking UniversityBeijing100871China Department of Physics Beijing Normal UniversityBeijing100875China Department of Physics Fudan UniversityShanghai200433China Yifei Fang方依霏Beijing Key Laboratory for Magnetoelectric Materials and Devices Beijing100871China Department of Physics Shanghai UniversityShanghai200444China State Key Laboratory of Magnetism Institute of PhysicsChinese Academy of SciencesBeijing100080China Department of Materials Science and Engineering College of EngineeringPeking UniversityBeijing100871China

Rare earth orthoferrites(RFeO3,R=Y,Gd,Sm,Nd)have recently attracted much attention due to their novel magnetic and electrical properties such as magneto-electrics,*** magneto-optics[1-3].The complex interactions between the two sublattices of R^3+and Fe^3+in RFeO3 provide the feasibility of control-ling spins in these solids,which makes them promising candidates for the spintronics[4].

关键词：磁有序 LaFeO3 量子阱信息存储磁矩特定方向可控性反铁磁

Deciphering key genes involved in cisplatin resistance in kidney renal clear cell carcinoma through a combined in silico and in vitro approach

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肿瘤学研究(英文) 2023年第6期31卷 899-916页

作者： MUNEEBA malik MAMOONA MAQBOOL TOOBA NISAR TAZEEM AKHTER JAVED ahmed UJAN ALANOOD SALGARNI FAKHRIA AAL JOUFI SULTAN SHAFI KALANAZI MOHAMMAD HADI ALMOTARED MOUNIR MSALEM BEKHIT MUHAMMAD JAMIL Services Hospital LahorePakistan Sabzazar Medical Center LahorePakistan BHU Pourmiana AttockPakistan Public Health Department University of Health SciencesLahorePakistan Department of Zoology Shah Abdul Latif UniversityKhairpurPakistan Department of Animal Sciences University of FloridaGainesvilleUSA Pharmacology and Toxicology Department College of Pharmacy Umm Al-Qura UniversityMakkahSaudi Arabia Department of Pharmacology College of PharmacyJouf UniversityAljoufSaudi Arabia Regional Laboratory and Blood Bank(Total Laboratory Automation) RiyadhSaudi Arabia Health Affairs in Najran New Najran General HospitalNajranSaudi Arabia Department of Pharmaceutics College of PharmacyKing Saud UniversityRiyadhSaudi Arabia PARC Arid Zone Research Center Dera Ismail KhanPakistan

The low survival rate of Kidney renal clear cell carcinoma(KIRC)patients is largely attributed to cisplatin *** than focusing solely on individual proteins,exploring protein-protein interactions could offer greater insight into drug *** this end,a series of in silico and in vitro experiments were conducted to identify hub genes in the intricate network of cisplatin resistance-related genes in KIRC *** genes involved in cisplatin resistance across KIRC were retrieved from the National Center for Biotechnology Information(NCBI)database using search terms as“Kidney renal clear cell carcinoma”and“Cisplatin resistance”.The genes retrieved were analyzed for hub gene identification using the STRING database and Cytoscape *** and promoter methylation profiling of the hub genes was done using UALCAN,GEPIA,OncoDB,and HPA ***,survival,functional enrichment,immune cell infiltration,and drug prediction analyses of the hub genes were performed using the cBioPortal,GEPIA,GSEA,TIMER,and DrugBank ***,expression and methylation levels of the hub genes were validated on two cisplatin-resistant RCC cell lines(786-O and A-498)and a normal renal tubular epithelial cell line(HK-2)using two high throughput techniques,including targeted bisulfite sequencing(bisulfite-seq)and RT-qPCR.A total of 124 genes were identified as being associated with cisplatin resistance in *** of these genes,MCL1,IGF1R,CCND1,and PTEN were identified as hub genes and were found to have significant(p<0.05)variations in their mRNA and protein expressions and effects on the overall survival(OS)of the KIRC ***,an aberrant promoter methylation pattern was found to be associated with the dysregulation of the hub *** addition to this,hub genes were also linked with different cisplatin resistance-causing ***,hub genes can be targeted with Alvocidib,Estradiol,Tretinoin,Capsaicin,Dronabinol,Metribolone,Calcitriol

关键词： KIRC Cisplatin resistance Chemotherapy Overall survival

A Survey of MANET Survivability Routing Techniques

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International Journal of Communications, Network and System Sciences 2013年第4期6卷 176-185页

作者： malik N. ahmed Abdul Hanan Abdullah Ayman El-Sayed Faculty of Computer Science & Information System University Technology Malaysia (UTM) Johor Malaysia

Mobile ad hoc networks have a wide range of application usage today, due to its great services, easy installation and configuration, and its other distinctive characteristics. In contrast, the attackers also have developed their own way to disrupt MANET normal operations. Many techniques, approaches and protocols have proposed to support Mobile Ad hoc Network (MANET) survivability in adversarial environment. Survivable of routing operations is the key aspects of the challenge in MANETs because most of destructive attacks classified as active attacks and all are intent to attack MANET routing operation to prevent it from providing it services in a right time. In this paper, we will discuss the most effective and practical initiatives have designed to keep MANET survive in an adversarial environment and how it supporting MANET availability.

关键词： MANET Survivability Routing Techniques

Seasonal Variations of Some Ecological Parameters in Tigris River Water at Baghdad Region, Iraq

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Journal of Water Resource and Protection 2011年第4期3卷 262-267页

作者： Adel Mashaan Rabee Bahaa malik Abdul-Kareem ahmed Saad Al-Dhamin 不详

This study aimed at using nine ecological parameters in evaluating the quality of the Tigris River for public usage, by choosing five sampling sites along the river in Baghdad area. These parameters included temperature, pH, the saturated ratio by dissolved oxygen (%sat), biological oxygen demand (BOD5), nitrate (NO3?1), phosphate (PO4?3), fecal coliform (FC) turbidity and total dissolved solids (TDS), and these parameters were used for calculating overall water quality index in the Tigris River at study area. The results showed high values of turbidity and TDS, as well as high count of FC in all study stations, while other studied parameters were within permissible limit defined by world health organization and Iraqi criteria. The results of the overall water quality index indicated that the Tigris River was in class medium, therefore the Tigris River water in study area is relatively not safe for direct domestic use in all seasons.

关键词： Ecological Parameters Fecal Ccoliform Tigris River Water Pollution

ROLE OF ACULASER THERAPY IN CEREBRAL PALSY CHILDERN (INITIAL DATA & RESULTS)

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World Journal of Acupuncture-Moxibustion 2004年第1期14卷 18-25页

作者： Shahzad Anwar malik Mohammad Nadeem Khan Imtiaz ahmed Abid Hareef Awan Anwar Shah's First C.P.& Paralysis Clinic and Research Center Children Hospital & Institute of Child HealthSheikh Zayed HospitalAnwar Shah's First C.P.& Paralysis Clinic and Research Center 17 C Main Boulevard Faisal Town LahoreLahoreLahore Pakistan 17 C Main Boulevard Faisal Town Lahore

A single, open and non-comparative study was conducted at Anwar Shah’s First C.P. & Paralysis Clinic and Research Center to evaluate the effects of Aculaser (acupoint-laser) Therapy for children suffering from cerebral palsy (CP) of various types. These children were further classified according to their major complaints. Analysis of the data indicated that 11 children with severe spasticity and stiffness all showed marked improvement (100% success rate); of the 8 children with epileptic fits, 6 patients had a significant reduction in the intensity, frequency and duration of epileptic fits, while the rest 2 cases showed no any improvement or aggravation (75% success rate); out of 5 children with cortical blindness, 2 cases showed complete recovery of vision and 3 had marked improvement (40% cure rate); out of 4 children with hearing difficulties, 2 showed marked improvement (50% success rate); out of 14 children with aphasis, 8 showed improvement (57% improvement rate). Results of this study show that Aculaser Therapy has a high improvement rate of CP children, not only improving the spasticity and stiffness but also the cortical blindness, epilepsy, deafness and speech.

关键词： Infantile cerebral palsy Acupoint-laser therapy Clinical observation

Nuclear Track Detectors for Relativistic Nuclear Fragmentation Studies: Comparison with Other Competitive Techniques

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Modern Instrumentation 2013年第3期2卷 49-59页

作者： Mukhtar ahmed Rana Gul Sher Shahid Manzoor Fariha malik Kanwal Naz Informatics Complex H-8 Islamabad Pakistan Isotope Applications Division PINSTECH Islamabad Pakistan Materials Division Directorate of Technology PINSTECH Islamabad Pakistan Physics Department COMSATS Institute of Information Technology (CIIT) Islamabad Campus Islamabad Pakistan The Pakistan Strategist Company An SPD Project PINSTECH-Admin Blk. Pakistan Institute of Nuclear Science and Technology (PINSTECH) Islamabad Pakistan Physics Department University of Balauchistan Quetta Pakistan National Tokamak Plasma and Fusion Project NILOP PAEC Islamabad Pakistan

The potential of the high resolution nuclear track detector (NTD) CR-39 is examined carefully for the measurement of relativistic nuclear projectile fragmentation cross sections and studies of related processes using the experience of many years of such measurements. The charge resolution and the charge resolving power of CR-39 detectors for the measurements of 158 A GeV 207Pb projectiles and their fragments are presented. Exposures of target-detector stacks, the chemical etching procedure and the nuclear track measurements are described in detail discussing precautions and possible errors. The procedures discussed are also valid for other NTDs. A comparison with electronic active detectors is also made considering important detection and measurement aspects. An experimental design proposing the co-use of NTDs with in-use active detectors is described.

关键词： Nuclear Track Detection Methodology (NTDM) CR-39 Detectors Nuclear Fragmentation Charge Resolution Fragmentation Cross Sections

A Study on the Pulmonary Manifestations of Rheumatoid Arthritis from a North Indian Town

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Open Journal of Respiratory Diseases 2013年第3期3卷 128-131页

作者： Nazish Fatima Mohammed Shameem Abida malik Parvez Anwar Khan Fatima Shujatullah Sohail ahmed Nabeela Department of Microbiology Jawaharlal Nehru Medical College Aligarh Muslim University Aligarh India Department of Orthopedics Jawaharlal Nehru Medical College Aligarh Muslim University Aligarh India Department of Tuberculosis and Chest Diseases Jawaharlal Nehru Medical College Aligarh Muslim University Aligarh India

Rheumatoid arthritis (RA) is a chronic systemic disease of unknown etiology characterized by articular involvement, extra-articular involvement, and the presence of serum rheumatoid factor. Pulmonary involvement in RA is a common extra-articular manifestation of rheumatoid arthritis (RA) that confers significant morbidity and mortality. We undertook this study to determine the prevalence and spectrum of pulmonary abnormalities in patients with rheumatoid arthritis (RA) from a North Indian town. 62 patients who met the American College of Rheumatology (formerly the American Rheumatism Association) 1987 classification criteria for RA were subjected to clinical examination of chest, X-Ray-chest (CXR), pulmonary function tests (PFT) and high resonance computed tomography (HRCT). 40.3% patients had some pulmonary symptoms with exertional dyspnoea in 21%, cough with expectoration in 17.7%, fine respiratory rales in 11.3%, patients X-ray chest bilateral lower zone haziness in 16% and prominent pulmonary vasculature in 3.2%. 43% had abnormal PFT-restrictive pattern in 29%, obstructive pattern 8% and mixed pattern in 6.4%. HRCT revealed abnormal findings in 33.8% commonest being ground glass pattern in both lower lobes 19.3%, sub pleural reticulations in 9.6%, pleural thickening in 3.2% and pulmonary vascular prominence in 1.6%. To provide optimal treatment, physicians must always consider the possibility of associated pulmonary manifestations when patients with RA are evaluated.

关键词： Rheumatoid Arthritis Pulmonary Manifestations

Diagnostic Performance of glmM Gene and Histological Stains for Detection of Helicobacter pylori in Gastric Biopsy from Patients Admitted to Wad Madani Teaching Hospital, Sudan

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Natural Science 2022年第8期14卷 343-352页

作者： Karima Ali Hamid Albadawi Abdelbagi Talha Abdalraheem Ali Babiker Mohammed Ibrahim malik Adam Dawoud Abakar Omer Mustafa Elsidig A Saeed Mohmed Bushra ahmed Elhadi Abdalla ahmed Department of Histopathology and Cytology Faculty of Medical Laboratory Sciences University of Gezira Wad Medani Sudan Department of Clinical Laboratory Sciences College of Applied Medical Sciences Jouf University Al Jouf Kingdom of Saudi Arabia Department of Medicine Faculty of Medicine University of Gezira Wad Medani Sudan Department of Medical Microbiology Faculty of Medical Laboratory Sciences University of Gezira Wad Medani Sudan

Helicobacter pylori is the microbial agent most responsible for gastro-duodenal ulcer and chronic gastritis, which can develop into carcinoma of the stomach. This study was performed in Wad Medani Teaching Hospital, Sudan to detect Helicobacter pylori in stomach samples, and evaluate the performance of the tests used, which were histological stains and PCR. Gastric biopsies were obtained from 105 referred patients during endoscopy, and fixed specimens examined by haematoxylin-eosin and Warthin-Starry silver stains, while DNA was extracted for glmM gene amplification. Epigastric pain was the most common symptom at 78% (82/105) and chronic gastritis recorded with 71% (68/105) of endoscopy results. Warthin-Starry silver stain gave 31% (33/105) as positive for Helicobacter pylori followed by glmM gene 27% (28/105) and haematoxylin-eosin 24% (25/105). The study indicated good performance of histological staining and high specificity of glmM gene in detection of Helicobacter pylori from gastric biopsies.

关键词： Helicobacter pylori Histological Stains glmM Gene Gastric Biopsy Sudan