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Intra.esica. instilla.ion of pla.elet-rich pla.ma.for trea.ment of interstitia. cystitis/bla.der pa.n syndrome:a.pilot study

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Current Urology 2024年第1期18卷 49-54页

作者： ahmed S.el Hefna.y Moha.ed a.tya.ahmed Ha.a. Esa. el sawy Moha.ed a.del-Ra.ik Na.r el-Ta.ey Ma.soura.Urology a.d Nephrology Center Faculty of MedicineMansoura UniversityMansouraEgypt

Objective:The a.m of this study wa. to eva.ua.e the fea.ibility of intra.esica. instilla.ion of pla.elet-rich pla.ma.PRP)to trea. interstitia. cystitis/bla.der pa.n syndrome(IC/BPS).Ma.eria.s a.d methods:Twenty PRP sa.ples were tested in vitro for sta.ility a.ter exposure to urine sa.ples with different pH.a.pilot study involving 21 fema.e pa.ients with IC/BPS wa. conducted,a.d 6 weekly doses of a.tologous PRP(50 mL)were *** were followed up a. the 2nd,4th,8th,a.d 12th weeks a.ter termina.ing *** prima.y endpoint wa. the visua. a.a.og sca.e(Va.)for pa.n,a.d the seconda.y endpoints included the IC symptom index,IC problem index of the O'Lea.y-Sa.t questionna.re a.d globa. response a.sessment,urine culture,a.d *** wa. defined a. a.reduction in Va. by 30%or more compa.ed with ba.a. level,a.d a.verse events were ***:The mea.±SD of Va. wa. significa.tly reduced compa.ed with ba.a. level(4.4±2.6 vs.8.8±1.1,respectively,p=0.001).Mea.while,80%of ca.es were considered successful,with a.50.1%reduction in the mea. score compa.ed with the ba.a. *** mea.±SD of IC symptom index a.d IC problem index significa.tly improved compa.ed with the ba.a. *** response a.sessment wa. ma.kedly,modera.ely,a.d slightly improved in 2(10%),10(50%),a.d 5(25%)pa.ients,respectively,a.d showed no cha.ge in 3(15%).Three pa.ients ha. positive urine cultures a. follow-up,but 1 withdrew a.ter 2 sessions beca.se of a.la.k of ***:Repea.ed intra.esica. instilla.ion of PRP could be considered a. effective a.d sa.e a.proa.h for trea.ing IC/BPS.

关键词： Bla.der pa.n syndrome Interstitia. cystitis Pla.elet-rich pla.ma

Ma.ic a.d felsic ma.ma.ism in the Wa.i Ka.a.a. a.ea. South Ea.tern Desert, Egypt: minera.ogy, geochemistry a.d geodyna.ic evolution during the Neoproterozoic in the Nubia. Shield

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a.ta.Geochimica 2024年第1期43卷 150-173页

作者： a.el a.Surour ahmed a.Ma.a.i Moha.ed a.el-Sobky Fa.ulty of Science Galala UniversityNew Galala CitySuez 43511Egypt Depa.tment of Geology Faculty of ScienceCairo UniversityGiza 12613Egypt Egyptia. Minera. Resources a.thority P.O.Box 11517AbbasiyaCairoEgypt

In the south Ea.tern Desert of Egypt,two contra.ting types of ma.ma.ism(ma.ic a.d felsic) a.e recorded in the Wa.i Ka.a.a. a.ea.a.d form the Ga.a. el Mota.hia.a. a.d Ga.a. Ba.uga.intrusions,*** two intrusions post-da.es ophiolitic a.d a.c a.socia.ions represented by serpentinite a.d meta.a.bro-diorite,*** ma.ic intrusion ha. a.ba.a. ultra.a.ic member represented by fresh peridotite,which is followed upwa.d by olivine ga.bro a.d a.orthositic or *** ma.ic intrusion perta.ns to the a.a.ka.-type ma.ic-ultra.a.ic intrusions in the a.a.ia.-Nubia. Shield(a.S)being of tholeiitic na.ure a.d empla.ed in a.typica. a.c *** the other ha.d,the Ga.a. Ba.uga.intrusion comprises three va.ieties of fresh a.type gra.ites of high K-ca.c a.ka.ine na.ure,which is pera.uminous a.d ga.netbea.ing in pa.ts.a.na.row therma. a.reole in the olivine ga.bro of the ma.ic intrusion wa. developed due to the intrusion of the Ba.uga.*** results in the development of a.hornfelsic mela.a.bro va.iety in which the composition cha.ged from tholeiitic to a.ca.c-a.ka.ine composition due to the a.dition of S_(i)O_(2),a._(2)O_(3),a.ka.is,lithosphile elements(LILEs) such a. Rb(70 ppm) a.d Y(28 ppm) from the felsic *** the therma. a.reole,Rb a.ounts 2-8 ppm a.d Y lies in the ra.ge elieved tha. the Ga.a. Ba.uga.felsic intrusion sta.ted to empla.e during the wa.ing sta.e of a. a.c system,with tra.sition from the pre-collisiona.(i.e.,a.c setting) to post-collisiona. a.d within pla.e *** from which the Ga.a. Ba.uga.gra.ites were fra.tiona.ed is high-K ca.c-a.ka.ine giving rise to a.typica. post-collisiona. a.type gra.ite(a.(2)-subtype) indica.ing a. origin from a. underpla.ing crusta. ***,it is stressed here tha. the younger gra.ites in the a.S a.e not exclusively post-collisiona. a.d within-pla.e but most likely they sta.ted to develop before closure of the a.c *** possible source(s) of ma.ic ma.ma.

关键词： Wa.i Ka.a.a. Ga.a. el Mota.ha.ra. ma.ic intrusion Ga.a. Ba.uga.felsic intrusion a.c setting Post-collision Within-pla.e

Cla.sica. ta.onomy,molecula. phylogeny a.d genetic a.a.ysis of the genus Exitia.us Ba.l,1929(Hemiptera.Cica.ellida.:Deltocepha.ina.)from Egypt

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Zoologica. Systema.ics 2024年第2期49卷 143-157页

作者： Ra.a. M.el-Ha.y ahmed F.el-Sa.ed Survey&Ta.onomy Depa.tment Plant Protection Research InstituteAgriculture Research CentreGizaEgypt Microbia. Genetics Depa.tment Biotechnology Research InstituteNational Research CentreGizaEgypt Egypt Center for Resea.ch a.d Regenera.ive Medicine(ECRRM) CairoEgypt

Egyptia. species of the lea.hopper genus Exitia.us Ba.l,1929,***(St?l,1855),***(Dista.t,1908),a.d *** Ross,1968 a.e ***,morphologica. descriptions,a.d a.key for their identifica.ion a.e *** this study,we used molecula. techniques to confirm morphologica. identifica.ion a.d detect phylogeny a.ong the three Exitia.us *** pa.tia. nucleotide sequences of the a.plified products obta.ned were determined by Ma.rogen *** nucleotide sequences of 28S rDNa.a.d COX genes of the EGY-a.C-9,EGY-a.C-4,a.d EGY-a.C-5 were determined by Ma.rogen Korea.bla.ted into BLa.T a. the Na.iona. Center for Biotechnology Informa.ion website(NCBI)a.d compa.ed with those deposited in the GenBa.k DNa.*** results represented the homology percenta.e between the pa.tia. sequences of the 28S rRNa.a.d COX genes from ea.h species a.d rela.ed species obta.ned from GenBa.k DNa.*** morphologica. identifica.ions of the three Exitia.us species were confirmed by molecula. cha.a.teriza.ion a.d sequencing of 28S rDNa.a.d COX genes a.d identified a. ***,***,a.d ***,their sequences of 28srDNa.a.d COX genes were deposited in GenBa.k with a. a.cession number(LC670610,LC670607,a.d OQ196105)for 28srDNa.gene a.d(LC775357,LC775358,a.d LC775359)for the COX gene.

关键词： a.chenorrhyncha Cha.smini ta.onomic 28S rDNA phylogenetic

Eva.ua.ion of urea.brea.h test a. a.dia.nostic tool for Helicoba.ter pylori infection in a.ult dyspeptic pa.ients

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World Journa. of Ga.troenterology 2024年第17期30卷 2302-2307页

作者： Zeina. Na.il ahmed Sa.d a.ma. Moha.ed el-Na.ser Depa.tment of Medica. Microbiology&Immunology Faculty of Medicine for Girls Al-Azhar UniversityNasr City 11754CairoEgypt

In this editoria.,we discuss the a.ticle in the World Journa. of *** a.ticle conducts a.meta.a.a.ysis of the dia.nostic a.cura.y of the urea.brea.h test(UBT),a.non-inva.ive method for detecting Helicoba.ter pylori(***)infection in *** is ba.ed on ra.ionuclide-la.eled *** methods,both inva.ive a.d non-inva.ive,a.e a.a.la.le for dia.nosing *** infection,inclu-ding endoscopy with biopsy,serology for immunoglobulin titers,stool a.tigen a.a.ysis,a.d *** guidelines recommend UBTs a. the prima.y choice for dia.nosing *** infection a.d for reexa.ining a.ter era.ica.ion *** is used to be the first choice non-inva.ive test due to their high a.cura.y,specificity,ra.id results,a.d ***,its performa.ce rema.ns una.fected by the distribution of *** in the stoma.h,a.lowing a.high flow of pa.ients to be *** its widesprea. use,the performa.ce cha.a.teristics of UBT ha.e been inconsistently described a.d rema.n incompletely *** a.e two UBTs a.a.la.le with Food a.d Drug a.ministra.ion a.prova.:The 13C a.d 14C *** tests a.e a.forda.le a.d ca. provide rea.-time *** ma. prefer the 13C test beca.se it is non-ra.ioa.tive,compa.ed to 14C which uses a.ra.ioa.tive isotope,especia.ly in young children a.d pregna.t *** there wa. heterogeneity a.ong the studies rega.ding the dia.nostic a.cura.y of both UBTs,13C-UBT consistently outperforms the *** ma.es the 13C-UBT the preferred dia.nostic ***,the provided findings of the meta.a.a.ysis empha.ize the significa.ce of precise considera.ions when choosing urea.dosa.e,a.sessment timing,a.d mea.urement techniques for both the 13C-UBT a.d 14C-UBT,to enha.ce dia.nostic precision.

关键词： Helicoba.ter pylori Urea.brea.h test Dia.nosis Dia.nostic test a.cura.y Meta.a.a.ysis

The role of polymorphic cytochrome P450 gene(CYP2B6)in B-chronic lymphocytic leukemia.B-CLL)incidence a.d outcome a.ong Egyptia. pa.ients

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Oncology Resea.ch 2024年第4期32卷 785-797页

作者： MENNa.a.-a.L Ma.DY MYOUSSEF ahmed el-SEBa.E SHERIF REFa.T a.a. el-Sa.D Division of Biochemistry Department of ChemistryFaculty of ScienceMansoura UniversityMansoura35511Egypt Hema.ology Unit Department of Clinical PathologyFaculty of MedicineMansoura UniversityMansoura35511Egypt Medica. Oncology Unit Oncology Center Mansoura UniversityMansoura35511Egypt Depa.tment of Genetics Mansoura University Children’s HospitalMansoura35511Egypt

Cytochromes P450(CYPs)pla. a.prominent role in ca.a.yzing pha.e I xenobiotic biotra.sforma.ion a.d a.count for a.out 75%of the tota. meta.olism of commercia.ly a.a.la.le drugs,including *** gene expression a.d enzyme a.tivity of CYPs a.e va.ia.le between individua.s,which subsequently lea.s to different pa.terns of susceptibility to ca.cinogenesis by genotoxic xenobiotics,a. well a. differences in the effica.y a.d toxicity of clinica.ly used *** resea.ch a.med to exa.ine the presence of the CYP2B6*9 polymorphism a.d its possible a.socia.ion with the incidence of B-CLL in Egyptia. pa.ients,a. well a. the clinica. outcome a.ter receiving cyclophospha.ide *** wa. isola.ed from whole blood sa.ples of 100 de novo B-CLL ca.es a.d a.so from 100 sex-a.d a.e-ma.ched hea.thy *** presence of the CYP2B6*9(G516T)polymorphism wa. exa.ined by PCR-ba.ed a.lele specific a.plifica.ion(a.a..Pa.ients were further indica.ed for receiving chemothera.y,a.d then they were followed *** CYP2B6*9 va.ia.t indica.ed a.sta.istica.ly significa.t higher risk of B-CLL under different genetic models,comprising a.lelic(T-a.lele vs.G-a.lele,OR=4.8,pa.d domina.t(GT+TT ***,OR=5.4,pa.ide chemothera.y,we found tha. the pa.ients with va.ia.t genotypes(GT+TT)were less likely to a.hieve remission compa.ed to those with the wild-type genotype(GG),with a.response percenta.e of(37.5%vs.83%,respectively).In conclusion,our findings showed tha. the CYP2B6*9(G516T)polymorphism is a.socia.ed with B-CLL susceptibility a.ong Egyptia. *** va.ia.t grea.ly a.fected the clinica. outcome a.d ca. serve a. a.good thera.eutic ma.ker in predicting response to cyclophospha.ide trea.ment.

关键词： B-CLL Xenobiotics Cytochromes P450 CYP2B6

Sta.da.diza.ion of meibomia. gla.d dysfunction in a. Egyptia. popula.ion sa.ple using a.non-conta.t meibogra.hy technique

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Interna.iona. Journa. of Ophtha.mology(English edition) 2024年第1期17卷 61-65页

作者： ahmed Moha.ed Ka.a.a.Zeina. el-Sa.a.a.y Mosta.a.a.i el-Helw Ta.er ahmed Ma.ky Moha.a. a.r Sa.a. Eddin a.delha.im Depa.tment of Ophtha.mology Kasr Al-Ainy HospitalCairo UniversityCairo 11431Egypt

a.M:To develop norma.ive da.a.for meibomia. gla.d dysfunction(MGD)pa.a.eters,using non-conta.t meibogra.hy technique of Sirius Costruzione Strumenti Ofta.mici(CSO)ma.hine,in a. Egyptia. popula.ion ***:Observa.iona.,cross-sectiona.,a.a.ytic study,in which 104 Egyptia. volunteers were *** upper lids were exa.ined,using“Sirius CSO”*** eyelid wa. given a.degree of meibomia. gla.d loss(MGL),which wa. ca.cula.ed by the softwa.e of the ***:Mea. percenta.e MGL in right upper lid wa. of 30.9%±12.6%,a.d tha. of left upper lid wa. 32.6%±11.8%.Thirty-four volunteers(32.7%)ha. first-degree MGL in their right upper lid,a.d 67.3%ha. second-degree *** volunteer(1%)ha. zero-degree MGL in left upper lid,28(26.9%)ha. first-degree loss,a.d 75(72.1%)ha. second-degree *** of MGL in right upper eyelid wa. not rela.ed to a.e,but degree of MGL in left upper eyelid increa.ed with *** wa. sta.istica.ly significa.t difference between both genders for degree of MGL in right eye(P=0.036)a.d in left eye(P=0.027).CONCLUSION:Nonconta.t meibogra.hy is a.useful non-inva.ive tool for dia.nosing *** is dia.nosed in 100%of a.pa.ently norma. individua.s;26.9%-32.7%of which ha.e first-degree MGL,a.d 67.3%-72.1%ha.e second-degree MGL.

关键词： Egyptia. popula.ion meibomia. gla.d dysfunction non-conta.t meibogra.hy sta.da.diza.ion upper lid

Ga.troesopha.ea. reflux a.ter per-ora. endoscopic myotomy:Ma.a.ement litera.ure

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World Journa. of Ga.troenterology 2024年第23期30卷 2947-2953页

作者： ahmed Ta.heed Ibra.im Ha.il Ba.cecioglu Mehmet Ya.niz Moha.ed el-Ka.sa. Depa.tment of Endemic Medicine Faculty of MedicineHelwan UniversityCairo 11795Egypt Depa.tment of Ga.troenterology Faculty of MedicineFirat UniversityElazig 23119Türkiye Liver Disea.e Resea.ch Center College of MedicineKing Saud UniversityRiyadh 7805Saudi Arabia

In this editoria.,we respond to a.review a.ticle by Na.i et a.,in which the a.thors discussed ga.troesopha.ea. reflux(GER)following perora. endoscopic myotomy(POEM).POEM is presently the prima.y thera.eutic option for a.ha.a.ia.which is both sa.e a.d effective.a.few a.verse effects were documented a.ter POEM,including *** dia.nostic criteria.were not clea. enough beca.se a.proxima.ely 60%of pa.ients ha.e a.long a.id exposure time,while only 10%experience reflux *** predictors of high disea.e incidence ha.e been identified,including old a.e,fema.e sex,obesity,a.d a.ba.eline lower esopha.ea. sphincter pressure of less tha. 45 *** technica. steps during the procedure,such a. a.lengthy or full-thickness myotomy,ma. further enha.ce the *** pump inhibitors a.e currently the first line of *** voices a.e increa.ingly a.voca.ing for the routine combining of POEM with a. endoscopic fundoplica.ion method,such a. perora. endoscopic fundoplica.ion or tra.sora. incisionless ***,more resea.ch is necessa.y to determine the sa.ety a.d effectiveness of these procedures in the long term for pa.ients who ha.e undergone them.

关键词： a.ha.a.ia Per-ora. endoscopic myotomy Ga.troesopha.ea. reflux disea.e Tra.sora. incisionless fundoplica.ion Perora. endoscopic fundoplica.ion

a.rhythmia.Detection by Using Cha.s Theory with Ma.hine Lea.ning a.gorithms

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Computers, Ma.eria.s & Continua 2024年第6期79卷 3855-3875页

作者： Ma.e a.ogha.a.a. Pa.sent el-ka.ra.y a.delmoty M.ahmed Ra.ha.elnemr Belga.em Boua.legue a.ma. el-sa.ed Ma.h a.d Computer Science Depa.tment Faculty of ScienceMenoufia UniversityShebin El-komEgypt College of Engineering Computer Science DepartmentEffat UniversityJeddahKingdom of Saudi Arabia Depa.tment of Computer Engineering College of Computer ScienceKing Khalid UniversityAbha61421Saudi Arabia Computer Science a.d Engineering Depa.tment Faculty of Electronic EngineeringMenoufia UniversityShebin El-komEgypt Clima.e Cha.ge Informa.ion Center a.d Expert Systems Agriculture Research CenterGizaEgypt

Hea.t monitoring improves life ***(ECGs or EKGs)detect hea.t *** lea.ning a.gorithms ca. crea.e a.few ECG dia.nosis processing *** first method uses ra. ECG a.d time-series *** second method cla.sifies the ECG by pa.ient *** third technique tra.sla.es ECG impulses into Q wa.es,R wa.es a.d S wa.es(QRS)fea.ures using richer *** ECG signa.s va.y na.ura.ly between huma.s a.d a.tivities,we will combine the three fea.ure selection methods to improve cla.sifica.ion a.cura.y a.d *** using a.l three a.proa.hes ha.e not been exa.ined till *** resea.chers found tha. Ma.hine Lea.ning(ML)techniques ca. improve ECG *** study will compa.e popula. ma.hine lea.ning techniques to eva.ua.e ECG *** a.gorithms—Support Vector Ma.hine(SVM),Decision Tree,Na.ve Ba.es,a.d Neura. Network—compa.e ca.egoriza.ion *** plus prior knowledge ha. the highest a.cura.y(99%)of the four ML *** cha.a.teristics fa.led to identify signa.s without cha.s *** 99.8%cla.sifica.ion a.cura.y,the Decision Tree technique outperformed a.l previous experiments.

关键词： ECG extra.tion ECG lea.s time series prior knowledge a.d a.rhythmia cha.s theory QRS complex a.a.ysis ma.hine lea.ning ECG cla.sifica.ion

Performa.ce Eva.ua.ion of a. Eva.ora.ive Cooling Pa. for Humidifica.ion-Dehumidifica.ion Desa.ina.ion

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Fluid Dyna.ics & Ma.eria.s Processing 2024年第10期20卷 2323-2335页

作者： Ibtissa. el a.uni Hicha. La.rim elhoussa.ne Oua.ida.ahmed a.t Errouhi Ra.hid el Boua.a.i Driss Zejli a.ua.if Sa.d a.va.ced Systems Engineering La.ora.ory National School of Applied SciencesIbn Tofail UniversityKenitra14000Morocco

The perfect combina.ion of renewa.le energy a.d desa.ina.ion technologies is the key to meeting wa.er dema.ds in a.cost-effective,efficient a.d environmenta.ly friendly *** desa.ina.ion technique by humidifica.iondehumidifica.ion is non-conventiona. a.proa.h suita.le for a.ea. with low infra.tructure(such a. rura. a.d decentra.ized regions)since it does not require perma.ent *** this study,this technology is implemented by using sola. energy a. a.source of therma. power.a.sea.a.er desa.ina.ion unit is considered,which consists of a.cha.ber with two eva.ora.ors(humidifiers),a.wetted porous ma.eria. ma.e of a.corruga.ed cellulose ca.dboa.d a.d a.condenser(dehumidifier).The eva.ora.ion system is tested with dry bulb tempera.ure a.d rela.ive a.r humidity *** results of numerica. simula.ions indica.e tha. higher inlet a.r velocities(from 0.75 to 3 m/s)lea. to a.decrea.e in theΔT,ΔRH,a.d *** the a.r rema.ning within the eva.ora.or for 30 cm,the tempera.ure differentia. increa.es to 5.7°C,a.compa.ied by a.39%rise in rela.ive humidity *** cha.ges result in a.significa.t enha.cement in humidifica.ion efficiency,a.hieving a.rema.ka.le efficiency level of 78%.However,a.wetta.ility va.ue of 630 m^(2)/m^(3)lea.s to a.sma.ler reduction of these *** the pa. thickness,pa.ticula.ly to 0.3 m,improves performa.ce by boostingΔT,ΔRH,a.d effectiveness,especia.ly for pa.s with a.wetta.ility of 630 m^(2)/m^(3),for which superior performa.ces a.e predicted by the numerica. tests.

关键词： Desa.ina.ion humidifica.ion dehumidifica.ion porous ma.eria. sola. energy eva.ora.or