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Intestinal parasitic infections among children under five years of age presenting with diarrhoeal diseases to two public health facilities in Hawassa, South Ethiopia

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Infectious Diseases of Poverty 2015年第1期4卷 105-112页

作者： Getamesay Mulatu ahmed zeynudin Endalew Zemene Serkadis Debalke Getenet Beyene Department of Medical Laboratory Technology Hawassa College of Health SciencesHawassaEthiopia Department of Medical Laboratory Sciences and Patholog

Background:Diarrhoea is the leading cause of morbidity and mortality in children under 5 years of age in developing countries,including *** is caused by a wide range of pathogens,including parasites,bacteria and *** aim of this study was to determine the prevalence of infection with intestinal parasites(IPs)(and types)among children under 5 years of age with diarrhoeal ***:A cross-sectional study was conducted at Adare Hospital and Millennium Health Centre,both located in Hawassa,South Ethiopia,from June 6 to October 28,*** under 5 years of age with diarrhoea who visited these health facilities during the study period were included in the *** relating to demography and risk factors associated with intestinal parasitic infections(IPIs)were gathered using a structured ***,fresh stool specimens were examined for IPs using the direct wet mount examination,followed by Ziehl-Neelsen staining of formol-ether concentrated samples,as per standard *** were analysed using SPSS Statistics 20 ***:A total of 158 children(51.3%male and 48.7%female)participated in the ***,the prevalence of IPs was 26.6%(42/158).Two species of IPs were detected in six children(3.8%).Entamoeba histolytica/dispar/moshkovskii was the predominant parasite identified(11.4%),followed by Giardia duodenalis(7.0%).The multivariable analysis revealed that the age group≥24 months was significantly associated(AOR=0.221,95%CI:0.085–0.576)with prevalence of ***:This study found that intestinal parasites are common among children with diarrheal *** most frequently detected species was ***/dispar/*** information about how to prevent diarrheal diseases in general and IPIs in particular should be provided to parents of young children.

关键词： Diarrhoea Intestinal parasites Children under 5 years Hawassa Ethiopia

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Anti-schistosomal activities of Echinops kebericho Mesfin root and Hagenia abyssinica (Bruce) J.F Gmel flower part crude extracts in Swiss albino mice

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Asian Pacific Journal of Tropical Medicine 2018年第10期11卷 570-575页

作者： Yonas Alemu Zeleke Mekonnen ahmed zeynudin Moti Yohannes Abdissa Biruksew Sultan Suleman School of Medical Laboratory Sciences Jimma University School of Veterinary Medicine Jimma University School of Pharmacy Jimma University

Objective: To evaluate the in vivo antischistosomal activities of the crude extracts of Echinops kebericho Mesfin(E. kebericho) root and Hagenia abyssinica(Bruce) J.F. Gmel(H. abyssinica) flower. Methods: Mice were infected with(150 ± 10) Schistosoma mansoni cercariae by paddling technique. Crude extracts were administered orally for five consecutive days at doses of 300, 600 and 1 200 mg/kg/day along with 200 mg/kg/day praziquantel and 3% tween 80 given as a control. Results: E. kebericho root extract showed a statistically significant(P < 0.05) reduction in fecal egg count of 64.44%, 42.96% & 26.82% and worm burden of 65.71%, 47.86% & 31.43% at treatment doses of 1 200 mg/kg/day, 600 mg/kg/day and 300 mg/kg/day, respectively. Similarly, H. abyssinica flower extracts showed a significant(P < 0.05) reduction in fecal egg count up to 84.57%, 77.06% & 63.89% and worm burden of 91.43%, 81.43% & 70.71% at a respective dose levels. In addition, a significant(P < 0.05) reduction in liver granuloma score was observed in all H. abyssinica administered dose groups and E. kebericho at 1 200 mg/kg/day dose group as compared to infected untreated control group. Conclusions: H. abyssinica and E. kebericho crude extracts show a promising antischistosomal activity.

关键词： Schistosoma mansoni Echinops kebericho Hagenia abyssinica Crude extract Antischistosomal activity Ethiopia

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