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An approach of the internal friction-dependent temperature changes for conventional and pure biogenic lubricating greases

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Friction 2024年第4期12卷 780-795页

作者： Leif ahme.erik KUHN miguelÁngel DeLGADO Department of mechanical engineering and Production management Hamburg University of Applied SciencesHamburg 20099Germany Department of Chemical engineering Research in Product Technology and Chemical Processes(Pro2TecS)University of HuelvaHuelva 21071Spain

This work investigated the temperature changes inside the bulk of lubricating greases under controlled high-shear stress conditions(250-500 s-1).For this purpose,a newly developed temperature-measuring cell called Calidus was successfully *** temperature changes(ΔT)have been related to the greases'components(thickener,base oil-type,and composition)and the structural degradation of the lubricating ***,a theoretical approach was proposed for calculating the internal temperature change of lubricating greases during shear *** greases showed an internal temperature profile characterised by a sudden rise inΔT within the first 4 h from starting the test and subsequentΔT decay until it reaches the steady state ***,it was found that greases C1 and C5,formulated with lithium and calcium soap,respectively,with different soap content(16.1 wt%and 9.7 wt%,respectively),but the same base castor oil,showed the highest value of the maximumΔT,c.a.3.2 K,and the most drastic drop ofΔ*** greases showed both the highest specific densities and heat *** addition,they showed the lowest ratio of expended energies(Rtee),which means more structural degradation in the stressed *** the contrary,the grease C3,with 13 wt%of Li-soap but the lowest base oil's viscosity,showed the lowest maximumΔT and the temperature profile was characterised by a moderate variation ofΔT along the *** biogenic grease B3 developed a low-temperature change in the group of pure bio-genic greases close to grease C3.

关键词： shear-induced structural degradation rheology temperature measurements lubricating greases density lubricating greases specific heat capacities

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动态mRI评价全组小肠蠕动

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国际医学放射学杂志 2014年第1期 67-67页

作者： A.menys s.A.Taylor A.emmanuel A.ahme.A.A.Plumb F.Odille 董春娇 Centre for medical Imaging University College London 3rd Floor East 250 Euston Rd London NW1 2PG England

目的用mRI软件分析志愿者小肠蠕动的可重复性,确定其检出药物诱导小肠蠕动变化的能力。方法本研究经皇家自由研究伦理委员会同意,均签署书面知情同意书。

关键词： mRI 小肠蠕动可重复性

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Randomized trial of chemoradiotherapy and adjuvant chemotherapy with nimustine (ACNU) versus nimustine plus procarbazine for newly diagnosed anaplastic astrocytoma and glioblastoma (JCOG0305)

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中国神经肿瘤杂志 2013年第1期11卷 21-21页

作者： shibui s Narita Y mizusawa J Beppu T Ogasawara K sawamura Y Kobayashi H Nishikawa R mishima K muragaki Y maruyama T Kuratsu J Nakamura H Kochi m minamida Y Yamaki T Kumabe T Tominaga T Kayama T sakurada K Nagane m Kobayashi K Nakamura H Ito T Yazaki T sasaki H Tanaka K Takahashi H Asai A Todo T Wakabayashi T Takahashi J Takano s Fujimaki T sumi m miyakita Y Nakazato Y sato A Fukuda H Nomura K Department of Neurosurgery and Neuro-Oncology National Cancer Center Hospital5-1-1 TsukijiChuo-kuTokyo 104-0045Japan

Objectives: Glioblastoma(GBm) is one of the worst cancers in terms of *** therapy consists of resection with concomitant *** to nimustine hydrochloride(ACNU),an alkylating agent,has been linked to methylguanine DNA methyltransferase(mGmT).Daily administration of procarbazine(PCZ) has been reported to decrease mGmT *** study investigated the efficacy of ACNU + PCZ compared to ACNU alone for GBm and anaplastic astrocytoma(AA).methods: Patients(20-69 years) who had newly diagnosed AA and GBm were randomly assigned to receive radiotherapy with ACNU alone or with ACNU + *** primary endpoint was overall survival(Os).This was designed as a phase Ⅱ/Ⅲ trial with a total sample size of 310 patients and was registered as UmIN-CTR ***: After 111 patients from 19 centers in Japan were enrolled,this study was terminated early because temozolomide was newly approved in *** median Os and median progression-free survival(PFs) with ACNU alone(n = 55) or ACNU + PCZ(n = 56) in the intention-to-treat population were 27.4 and 22.4 months(P = 0.75),and 8.6 and 6.9 months,*** median Os and median PFs of the GBm subgroup treated with ACNU alone(n = 40) or ACNU + PCZ(n = 41) were 19.0 and 19.5 months,and 6.2 and 6.3 months,*** 3/4 hematologic adverse events occurred in more than 40% of patients in both arms,and 27% of patients discontinued treatment because of adverse ***: The addition of PCZ to ACNU was not beneficial,in comparison with ACNU alone,for patients with newly diagnosed AA and GBm.

关键词：星形细胞母细胞随机试验放疗胶质变性化疗 mGmT

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