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Prevalence and Factors Associated with Low Back Pain among Healthcare Workers in Two Hospitals in Yaoundé-Cameroon: A Cross-Sectional Study

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Open Journal of Rheumatology and Autoimmune Diseases 2024年第3期14卷 89-107页

作者： Brian Gweha ahmadou musa jingi Baudelaire Fojo Talongong Claude Tayou Madeleine Singwé-Ngandeu Department of Clinical Sciences Faculty of Health Sciences The University of Bamenda Bamenda Cameroon Faculty of Medicine and Biomedical Sciences The University of Yaound Yaound Cameroon The Rheumatology Unit The Yaound Central Hospital Yaound Cameroon The Hematology Laboratory The Yaound University Teaching Hospital Yaound Cameroon

Background: Low back pain (LBP) is a very common health problem amongst the general population and a major cause of disability that affects work performance and well-being. Healthcare workers (HCWs) are especially at risk of developing LBP because of physical and emotional factors. Little is known about the burden of LBP in Cameroon. Objective: To determine the prevalence of low back pain and identify its associated factors among healthcare workers. Methods: A cross-sectional study using a self-administered questionnaire was conducted among healthcare workers in the Yaound Central Hospital and the Yaound University Teaching Hospital. The questionnaire collected data regarding recent, past year and lifetime occurrences of LBP, socio-demographics and work conditions. Data were analysed using IBM Statistical Package for Social Sciences (SPSS) version 26. Results: A total number of 268 HCWs participated in the study, including 197 (73.5%) females and 71 (26.5%) males. The mean age of the study participants was 40.60 8.38 years (extremes of 20 and 65 years). The lifetime, annual, and point prevalences of LBP among the participants were 67.5% (CI: 61.6 - 73.1), 61.5% (CI: 55.6 - 67.1) and 35.7% (CI: 29.7 - 41.5) respectively. Multivariate analysis confirmed a moderate stress level, a sedentary lifestyle, working in the medicine and specialities department, lifting heavy objects and bending to work as associated factors to LBP. Most sufferers had a minimal functional disability (65.7%) while 34.3% had a moderate to severe disability. Conclusions: Healthcare providers have a considerably high prevalence of low back pain. Factors associated with LBP found in this study were similar to those widely recognized in the literature. A substantial proportion of healthcare providers are suffering from functional disability associated with low back pain, affecting their social and work lives. There is a need for multilevel interventions to prevent and control low back pain in this hi

关键词： Prevalence Associated Factors Low Back Pain Healthcare Workers Yaoundé

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Prevalence of Re-Hospitalization for Heart Failure in a Cameroonian Tertiary Hospital: A Cross-Sectional Study

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World Journal of Cardiovascular Diseases 2023年第6期13卷 333-340页

作者： Amalia Owona Ning Lom Bryan-Bill ahmadou musa jingi Dieudonne Danwe Alain Patrick Menanga Faculty of Medicine and Biomedical Sciences University of Yaoundé I Yaoundé Cameroon Cardiology Unit Yaoundé General Hospital Yaoundé Cameroon Faculty of Health Sciences University of Bamenda Bamenda Cameroon

Aim: To determine the prevalence of re-hospitalization for heart failure in the cardiology unit of the Yaoundé General Hospital. Study Design: This was a retrospective cross-sectional study from January 2015 to December 2020. Patients and Methods: Patients aged at least 18 years who were hospitalized for heart failure during the study period were included. Data were collected using a predesigned form and were analyzed using Epi InfoTM version 7.2.2. Results: We included a total of 160 patients. The prevalence of re-hospitalization was 30.6%. Re-hospitalized patients had a mean age of 71.0 ± 13.9 years and a sex ratio of 1.6. The most common etiologies of HF were hypertensive heart disease (36.7%), followed by dilated cardiomyopathy (22.5%), and atrial fibrillation (16.3%). More than two third had class IV NYHA disease (77.6%). Most of them also had HFrEF (71.4%) and anemia (77.6%). Conclusion: There is a high rate of re-hospitalization in the cardiology unit of the Yaoundé General Hospital with most of these patients having old age and severe HF.

关键词： Re-Hospitalization Heart Failure Yaoundé Cameroon

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Clinical Presentations and Outcome of Cardiovascular Emergencies in Yaounde: A Cross-Sectional Study

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World Journal of Cardiovascular Diseases 2018年第2期8卷 133-142页

作者： Ba Hamadou Yaya Toure Kalissou ahmadou musa jingi Sylvie Ndongo Amougou Sandrine Edie Dikosso Rodrigue Njouoguep Samuel Kingue Department of Internal Medicine and Specialties Faculty of Medicine and Biomedical Sciences University of Yaounde 1 Yaounde Cameroon Internal Medicine Service Cardiology Unit Yaounde Central Hospital Yaounde Cameroon Yaounde Emergency Center Yaounde Cameroon

Background: Cardiovascular emergencies have become a public health problem with a high burden in low-income settings. This is due to the high rates of cardiovascular risk factors that are fast reaching epidemic?proportions. There is paucity of data on cardiovascular emergencies to guide repost strategies in our setting. Our aim was to determine the clinical presentation and outcome of cardiovascular emergencies at Yaounde Emergency Center.?Methods: We carried out this cross-sectional study between June 2015 and May 2017. We included all patients with confirmed cardiovascular emergency. We consecutively collected data on socio-demography, symptoms on admission, past history, clinical findings, and final diagnosis at discharge or in the event of death. Results: Of the 8285 patients admitted for medical emergencies, 388 (4.7%) were cardiovascular emergencies. Their mean age was 59.5 ± 13.8 years, and 59% were males. The Medical Emergency Aid Service was the means of transporting 4% of patients. The median time of arrival at the hospital was 48 hours. Symptoms on admission were mainly weakness of a limb (43.8%), and altered consciousness (33.5%). The most common cardiovascular emergencies were ischemic stroke (30.9%), hypertensive emergency (21.4%), and hemorrhagic stroke (16.5%). The most common comorbidity was diabetes (21.9%). The death rate in the 24 - 72 hours was 14.4%. The causes of death were hypertensive emergency (35.7%), and hemorrhagic stroke (30.3%). Conclusion: Stroke and hypertensive emergency were the most frequent cardiovascular emergencies. The early mortality was high. Hemorrhagic stroke and hypertensive emergencies accounted for most cases of death.

关键词： Cardiovascular Emergencies Ischemic Stroke Hemorrhagic Stroke Cameroon

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Parasympathetic Dysfunction in Black African Patients with Heart Failure:A Cross-Sectional Study in Sub-Saharan Africa

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World Journal of Cardiovascular Diseases 2020年第4期10卷 178-187页

作者： Ba Hamadou Sylvie Ndongo Amougou Ismaila Daouda Chris Nadege Nganou-Gnindjio Liliane Mfeukeu-Kuate Jerome Boombhi ahmadou musa jingi Alain Menanga Samuel Kingue Department of Medicine and Specialties Faculty of Medicine and Biomedical SciencesUniversity of Yaounde IYaoundeCameroon Cardiology Unit Central Hospital of YaoundeYaoundeCameroon Cardiology Unit University Teaching Hospital of YaoundeYaoundeCameroon Faculty of Medicine and Biomedical Sciences University of Yaounde IYaoundeCameroon Cardiology Unit Medicine BGeneral Hospital of YaoundeYaoundeCameroon

Background: Heart Failure (HF) is a major public health problem worldwide. Neurohormonal changes associated with HF are current therapeutic targets. The parasympathetic system in HF has not been well studied especially in black Africans. Aim: This study aimed to report on the prevalence and determinants of parasympathetic dysfunction in patients with heart failure in sub-Saharan Africa. Methods: We conducted a cross-sectional study between December 2017 and April 2018 in the outpatient and inpatient departments in two teaching hospitals in Yaounde-Cameroon. Cases were patients with HF matched with controls without HF according to age, sex, and risk factors (hypertension, diabetes, and obesity). We assessed the parasympathetic function via the Deep Breathing Test using an electrocardiograph. Results: We recruited 35 patients in each group. The mean age was 57 ± 11.68 years. Vagal dysfunction was seen in 51.4% of cases and 11.4% of controls (aOR: 10.1 [95% CI: 2.7 - 38.3], p = 0.001). This risk increased with the severity of HF-aOR: 11.8, [95% CI: 1.8 - 77.9], p = 0.01 for dyspnea stage III-IV, and aOR: 9.27, [95% CI: 1.3 - 65.3], p = 0.025) for HF with reduced Ejection fraction. This risk was not associated with the classic cardiovascular risk factors. Conclusion: Parasympathetic dysfunction as assessed with the Deep Breathing Test was seen in over half of the patients with HF and this was associated with the severity and type of HF.

关键词： Heart Failure Parasympathetic Dysfunction Heart Rate Variability Deep Breathing Test

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Burden, Type, and Associated Factors of Thyroid Dysfunction in Patients with Heart Failure in Sub-Saharan Africa: A Cross-Sectional Study

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World Journal of Cardiovascular Diseases 2021年第11期11卷 485-497页

作者： Liliane Mfeukeu-Kuate Honoré Kemnang Yemele ahmadou musa jingi Martine Etoa Jan Rene Nkeck Jerome Boombhi Sylvie Ndongo Amougou Chris Nadege Nganou-Gninjio Mesmin Yefou Dehayem Ama Moor Vicky Faculty of Medicine and Biomedical Sciences The University of Yaounde Yaounde Cameroun The Yaounde Central Hospital Yaounde Cameroun Faculty of Health Sciences The University of Bamenda Bamenda Cameroon Faculty of Medicine and Pharmaceutical Sciences The University of Douala Douala Cameroun The Yaounde General Hospital Yaounde Cameroon The Yaounde University Teaching Hospital Yaounde Cameroun

Background: Various thyroid abnormalities have been reported during heart failure (HF). The present study aimed to evaluate the burden, type, and associated factors of thyroid disorders in Cameroonian patients with heart failure. Materials and Methods: We conducted a cross-sectional study from January to May 2020, involving volunteer adults followed for heart failure at the Yaoundé Central Hospital. Those receiving treatment that could cause thyroid dysfunction were excluded. Thyroid hormone levels (TSH, free T3, and free T4) were measured by enzyme-linked immunosorbent assay. Results: A total of 63 patients (30 women;47.6%) were included. The median age was 65 (IQR: 56 - 70) years. The main etiology of heart failure was hypertension (52.4%) followed by valvular heart disease (14.3%). Thyroid dysfunction was seen in 38 (60.3%, [95% CI: 47.2 - 72.4]) patients, of which 30 (79%) had hypothyroidism and 8 (21%) had hyperthyroidism. The most frequent thyroid dysfunction was Low T3 syndrome in 27% (95% CI: 16.6 - 39.7) of the study population followed sub-clinical hypothyroidism in 19.1% (95% CI: 10.3 - 30.9) of patients. Patients with HF and reduced ejection fraction (HFrEF) were more likely to have hypothyroidism than those with preserved ejection fraction (OR: 3.5, [95% CI: 1.2 - 9.9], p = 0.016). Also, patients with more than one hospital admission in the past 12 mo

关键词： Thyroid Dysfunction Heart Failure Sub-Saharan Africa

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Cardiovascular Risk Burden in Sub-Saharan Africans with Rheumatoid Arthritis: A Hospital-Based Study in Yaounde, Cameroon

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Open Journal of Rheumatology and Autoimmune Diseases 2016年第1期6卷 1-9页

作者： Madeleine Singwe-Ngandeu Mickael Essouma Vicky Jocelyne Ama Moor ahmadou jingi musa Alain Patrick Menanga Caroline Ngoufack Sandrine Sa’a Lontsi Thierry Ntandzi Yolande Vanessa Ayi Efoua Mireille Cathy Melong Pianta Faculty of Medicine and Biomedical Sciences The University of Yaoundé I Yaounde Cameroon Rheumatology Unit Yaounde Central Hospital Yaounde Cameroon Biochemistry Laboratory Yaounde University Teaching Hospital Yaounde Cameroun Cardiology Unit Yaounde General Hospital Yaounde Cameroon

Introduction: Studies on RA (rheumatoid arthritis) and cardiovascular risk in African countries are scarce. Objective: To investigate the relationship between RA and cardiovascular risk in Cameroonian patients. Methodology: In 50 Black RA patients and 51 matched healthy individuals from the general population, we studied cardiovascular risk factors validated by the WHO. Cardiovascular risks estimates were carried out using WHO risk charts for the African region. Epi-info, R and SPPS were used for the statistical analysis. Results: Overall and abdominal adiposity as expressed by increased body mass index and abdominal obesity, were all markedly increased in RA patients compared to non-RA subjects [70% vs. 47%, OR (95% CI) = 2.62 (1.16 - 5.94), p = 0.026;and 54% vs. 33%, OR (95% CI) = 2.34 (1.05 - 5.25), p = 0.045 respectively]. RA patients were more physically inactive than their non-RA counterparts (20% vs. 0, p = 0.001). Whereas RA was associated with a reduced odds of alcoholism [OR (95% CI) = 0.19 (0.06 - 0.62), p = 0.005]. Increased BMI seemed to occur independently of methotrexate (p = 0.76), hydroxychloroquine (p = 0.59), corticosteroids (p = 0.79) treatments, and independently of sex (p = 0.15), age (p = 0.67), and sedentary lifestyle (p = 0.16) in RA patients;but their BMI was weakly correlated with disease duration (r = 0.26;p = 0.074). Meanwhile, male gender was associated with a reduced odds of abdominal obesity [OR (95% CI) = 0.02 (0 - 0.4), p = 0.011]. Cardiovascular risk, comparable by proportions between RA and non-RA subjects, was low in 26 patients (78.8%) and 30 non-RA subjects (83.3%) respectively. Conclusion: Despite the high adiposity burden and a sedentary lifestyle experienced by RA patients compared to their healthy counterparts, RA was not associated with cardiovascular risk as estimated by WHO risk charts.

关键词： Rheumatoid Arthritis Excess Adiposity Physical Inactivity Cardiovascular Risk World Health Organization Risk Charts

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Management Dilemma of Pulmonary Embolism Associated with Haemorrhagic Stroke in Low-Income Settings: A Case Report

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Case Reports in Clinical Medicine 2022年第5期11卷 160-166页

作者： Liliane Mfeukeu-Kuate Nadège Nganou-Gnindjio Andy Tchouanlong Tabuguia Honoré Kemnang Yemele Boris Kom Wandji ahmadou musa jingi Oummoul Koulsoumi Claude Ewane Essoh Johane Bekoe Dieudonné Danwe Alain Menanga Faculty of Medicine and Biomedical Sciences University of Yaoundé I Yaoundé Cameroon Central Hospital of Yaoundé Yaoundé Cameroon Faculty of Health Sciences University of Bamenda Bamenda Cameroon General Hospital of Yaoundé Yaoundé Cameroon

Management of thromboembolic disease in an acute bleeding circumstance like haemorrhagic stroke is a real challenge in low-income settings. We report a case of a 37-year-old woman who was treated in the neurologic service for a haemorrhagic stroke that occurred one week after a caesarean section. Six weeks after her discharge, she presented signs of bilateral deep vein thrombosis and pulmonary embolism confirmed by venous Doppler ultrasound and a thoracic angiography respectively. Transthoracic cardiac ultrasound showed right ventricular dysfunction with a clot in the right atrium. Considering the high risk of complications due to anticoagulant treatment, surgical treatment and a vena cava filter were proposed. But it could not be performed because it was not accessible. After a multidisciplinary consultation meeting and informed consent of the patient, anticoagulant treatment was the preferred expectation. Three weeks after the beginning of the anticoagulant therapy, the evolution was favourable, and the patient was discharged.

关键词： Dilemma Pulmonary Embolism Haemorrhagic Stroke Cameroon

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Prevalence and Risk Factors of Peripheral Artery Disease in a Group of Apparently Healthy Young Cameroonians: A Cross-Sectional Study

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World Journal of Cardiovascular Diseases 2018年第2期8卷 111-122页

作者： Félicité Kamdem Yacouba Njankouo Mapoure Ba Hamadou Fanny Souksouna ahmadou musa jingi Caroline Kenmegne Fernando Kemta Lekpa Jaff Fenkeu Kweban Gisèlei Mandy Jean Pierre Nda Mefo’o Henry Luma Marie Solange Doualla Internal Medicine Service Douala General Hospital Douala Cameroon Faculty of Medicine and Pharmaceutical Sciences University of Douala Douala Cameroon Faculty of Medicine and Biomedical Sciences University of Yaounde I Yaounde Cameroon Chemical Pathology Laboratory Douala General Hospital Douala Cameroon

Background: The?burden of peripheral artery disease (PAD) is not well known among apparently healthy people in Africa. Aim: To determine the prevalence and associated risk factors of PAD in a group of blood donors seen at the Douala General Hospital—Cameroon. Methods: Between 1st November 2015 and 30th April 2016, we carried out a cross-sectional study. Participants were consenting adults of both sexes, aged ≥ 21 years who presented for blood donation, and were tested HIV negative. We collected socio-demographic data and their past history. We carried out a physical examination and measured their Ankle-Brachial Index (ABI). We defined PAD as an ABI Results: We recruited 103 participants, 55.4% males. The mean age was 33 ± 10 years. The mean ABI on left and right leg was 1.04 ± 0.1 and 1.02 ± 0.1respectively. ABI was higher in males than females both legs (p 0.05). PAD was seen in 11 (10.7%) participants. This was higher in females than males (3.6% versus 19.2%, p = 0.026). Among those with PAD, 8 (72.7%) were asymptomatic (Males: 100% versus Females: 66%, p = 0.9). After adjusting for age and gender, sedentary lifestyle (aOR: 7.14, [95% CI: 1.38 - 33.3], p = 0.019), and female gender (aOR: 6.2, [95% CI: 1.26 - 30.5], p = 0.025) were significantly associated with PAD. Conclusion: The prevalence of PAD was high in this group of HIV negative blood donors, most of whom were asymptomatic. This was associated with females, and a sedentary lifestyle.

关键词： Peripheral Artery Disease ABI Prevalence Risk Factors Douala

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Epidemiology, Clinical Presentations and In-Hospital Mortality of Venous Thromboembolism at the Douala General Hospital: A Cross-Sectional Study in Cameroon, Sub-Saharan Africa

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World Journal of Cardiovascular Diseases 2018年第2期8卷 123-132页

作者： Félicité Kamdem Bertrand Hugo Mbatchou Ngahane Ba Hamadou Agborbessong Mongyui Marie Solange Doualla ahmadou musa jingi Anastase Dzudie Yves Monkam Henri Ngote Sidick Mouliom Caroline Kenmegne Jaff Kweban Fenkeu Romuald Hentchoya Albert Kana Aminata Coulibaly Henry Luma Internal Medicine Service Douala General Hospital Douala Cameroon Faculty of Medicine and Pharmaceutical Sciences University of Douala Douala Cameroon Faculty of Medicine and Biomedical Sciences University of Yaounde I Yaounde Cameroon Intensive Care Unit Douala General Hospital Douala Cameroon

Background: Venous thromboembolism (VTE) is a major cause of morbidity and mortality worldwide. It is also the most common complication in hospitalized patients. Aims:?To?study the in-hospital prevalence of VTE, describe the socio-demographic characteristics of patients, determine the frequency of risk factors, describe the clinical presentations, and determine the short term outcome of VTE in hospitalized patients in a low-income tertiary hospital setting.?Methods: We carried out a cross-sectional descriptive retrospective study over a period of 6 years and 4 months (January 2008 to April 2014) in the Douala General Hospital—Cameroon. Patients were cases of confirmed venous thromboembolic disease (VTE).?Results: A total of 78 case files were retained for this study, giving an in-hospital prevalence of 4.4 per 1000 admissions. There were 42 (53.8%) males and 36 (46.1%) females. Their ages ranged from 18 to 89 years (median: 53 years, [IQR: 40?-?61]).?There were 37 (47.4%) cases of Deep Vein Thrombosis (DVT), 31 (39.7%) cases of Pulmonary Embolism (PE), and 10 (12.8%) cases of PE associated with DVT (12.8%). The main risk factors were obesity (44.9%), hypertension (37.2%), immobility (20.5%), and long-haul travel (17.9%). The most frequent clinical presentations in PE were dyspnea (80.5%) and chest pain (65.9%). There were 8 (10%) in-hospital deaths. Conclusion: About twelve cases of VTE are seen yearly at the DGH, with an in-hospital mortality of ten percent. Obesity and hypertension were the main risk factors, with dyspnea and chest pain being the main clinical manifestations in PE, and lower limb swelling the main symptom in DVT.

关键词： Epidemiology Clinical Presentation Mortality Venous Thromboembolism Cameroon Sub-Saharan Africa

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Epidemiology of Venous Thrombo-Embolic Disease in Yaounde: A Cross-Sectional Study in Sub-Saharan Africa

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World Journal of Cardiovascular Diseases 2019年第5期9卷 360-369页

作者： Sylvain Raoul Simeni Njonnou Chris Nadège Nganou-Ngnindjo Ba Hamadou Bonaventure Jemea ahmadou musa jingi Jerome Boombhi Aimée Tiodoung Timnou Marie-Josiane Ntsama Essomba Lydienne Alida Tonye Aicha Mefire Yap Murielle Florence Helles Lema Liliane Mfeukeu-Kuate Sylvie Ndongo Amougou Samuel Kingue Department of Internal Medicine and Specialties Faculty of Medicine and Biomedical Sciences University of Yaounde I Ya-oundé Cameroon Yaounde Central Hospital Yaoundé Cameroon Department of Surgery and Specialties FMSB University of Yaounde I Yaoundé Cameroon Yaounde University Teaching Hospital Yaoundé Cameroon Yaounde General Hospital Yaoundé Cameroon

Background: Venous thromboembolic disease (VTE) is one of the main causes of cardiovascular death and a public health problem worldwide. It is?one of the most complications in admitted patients, particularly inlow-income settings. The epidemiological data on VTE are still lacking. Methods: We carried out a cross-sectional study in three hospitals in Yaoundé. We retrospectively reviewed records of patients admitted for VTE from January 2013 to December 2017. We collected data on socio-demography, clinical presentation, venous Doppler/pulmonary CT scan, and outcome. Results: We included 93 patients (43 males) with VTE. Their mean age was 53.3 ± 16.6 years. There were 46 (49.5%) cases of Deep Vein Thrombosis (DVT), 36 (38.7%) cases of Pulmonary Embolism (PE), and 11 (11.8%) cases of PE associated with DVT. The main risk factors were obesity/overweight (58.1%), immobility (43%), HIV infection (22.6%), prior admission (22.6%), and long trip (19.4%). The most frequent clinical presentation for PE was dyspnea (100%), tachypnea (87.2%), and chest pain (70.2%). For DVT, limb pain (93%), calf stiffness (86%), limb volume > 3 cm (82.4%) were the most common presentation. There were 9 (9.7%) in-hospital deaths. Mean hospital stay was 20.7 ± 30.8 days. Conclusion:VTE is underdiagnosed in our setting. Obesity and immobility were the main risk factors. Dyspnea and tachypnea were the main clinical presentation for PE whereas limb pain and calf stiffness were the main symptoms for DVT. In-hospital mortality is still high.

关键词： Venous Thromboembolic Disease Epidemiology Yaounde Sub-Saharan Africa

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