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Early Childho.d Develo.ment.(0 - 6 Years o.d) fro. Healt.y t.0}Pat.o.o.ic: A Review o. t.e Lit.rat.re

o.en Jo.rnal o. Medical Psycho.o.y 2020年第3期9卷 100-122页

作者： Chkirat. Meriem Mammad Khao.la Cht.bo. Ghizlane Mdaghri Alao.i Asmaa ahami o. t. ahmed Clinical Neuro.cience and Applied Nut.it.o. Unit Department of Biology Faculty of Sciences Kenitra Morocco Pediat.ic Service 2 Children’s Hospital University Hospital Center (UHC) Ibn Sina Rabat Morocco Research t.am in Co.genit.l Ano.alies Faculty of Medicine and Pharmacy Mohammed V University Rabat Morocco

Early childho.d develo.ment.invo.ves an appro.riat. glo.al int.rvent.o. co.cerning t.e different.areas o. develo.ment.such as: physical, co.nit.ve, language and so.io.emo.io.al [1]. Especially during t.e first.six ye... 详细信息

t.le="t.xt.align:just.fy;"> Early childho.d develo.ment.invo.ves an appro.riat. glo.al int.rvent.o. co.cerning t.e different.areas o. develo.ment.such as: physical, co.nit.ve, language and so.io.emo.io.al [1]. Especially during the first six years of life in an adequate environment rich in exchange and interaction. We will present in this article a review of the literature concerning normal early childhood development, focus firstly in normal development’s steps, the importance of first experiences and first aid with a stable and caring attachment figure. second, we will describe the various developmental disorders, occurring during this age group which extends from birth to 6 years and based on the DSM5 classification, namely that developmental delay may concern only one aspect of development (e.g. language delay or motor delay specifically) or concern the different aspects of development (overall development delay). The dynamics of development is also important to clarify because schematically we contrast the pathologies fixed to progressive pathologies (where we find the concepts of stagnation or regression in the development of the child). We will discuss in the third chapter, the interest of early detection as well as the multiple clinical and psychometric diagnostic tools, which aim to detect any delay or disorder in order to initiate appropriate care and minimize the long-term consequences.

关键词： Early Childho.d No.mal Develo.ment Develo.ment.l Diso.der Early Screening Remediat.o.

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Engineering nano.edicines fo. immuno.enic eradicat.o. o. cancer cells:Recent.t.ends and synergist.c appro.ches

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Act. Pharmaceut.ca Sinica B 2024年第6期14卷 2475-2504页

作者： ahmed o.Elzo.hby o.ar Samir Hagar E.Emam ahmed So.iman Riham M.Abdelgalil Yo.na M.Elmo.shedy Kadria A.Elkho.airy Mahmo.d L.Nasr Divisio. o. Engineering in Medicine and Divisio. o. Renal Medicine Department of MedicineBrigham and Women's HospitalHarvard Medical SchoolBoston 02115MAUSA Cancer Nano.echno.o.y Research Labo.at.0}y(CNRL) Faculty of PharmacyAlexandria UniversityAlexandria 21521Egypt

Resist.nce t.0}cancer immuno.herapy is mainly at.ribut.d t.0}po.r t.mo. immuno.enicit. as well as t.e immuno.uppressive t.mo. micro.nviro.ment.t.E)leading t.0}failure o. immune *** t.erapeut.c st.at.gies including chemo.herapy,radio.herapy,pho.o.ynamic,pho.o.hermal,magnet.c,chemo.ynamic,so.o.ynamic and o.co.yt.c t.erapy,have been develo.ed t.0}induce immuno.enic cell deat.(ICD)o. cancer cells and t.ereby elicit.immuno.enicit. and bo.st.t.e ant.t.mo. immune ***,many challenges hamper t.e clinical applicat.o. o. ICD inducers result.ng in mo.est.immuno.enic ***,we o.t.ine t.e current.st.t. o. using nano.edicines fo. bo.st.ng ICD o. cancer ***,synergist.c appro.ches used in co.binat.o. wit. ICD inducing nano.edicines fo. remo.eling t.e t.E via t.rget.ng immune checkpo.nt.,phago.yt.0}is,macro.hage po.arizat.o.,t.mo. hypo.ia,aut.0}hagy and st.o.al mo.ulat.o. t.0}enhance immuno.enicit. o. dying cancer cells were *** furt.er highlight.t.e emerging t.ends o. using nano.at.rials fo. t.iggering amplified ICD-mediat.d ant.t.mo. immune *** ret.culum lo.alized ICD,fo.used ult.aso.nd hypert.ermia,cell membrane camo.flaged nano.edicines,amplified react.ve o.ygen species(Ro.)generat.o.,met.llo.immuno.herapy,io. mo.ulat.0}s and engineered bact.ria are amo.g t.e mo.t.inno.at.ve *** challenges,merit. and demerit. o. ICD inducer nano.edicines were also.discussed wit. shedding light.o. t.e fut.re ro.e o. t.is t.chno.o.y in impro.ing t.e o.t.o.es o. cancer immuno.herapy.

关键词： Immuno.enic cell deat. Immuno.enic eradicat.o. Nano.edicines Drug delivery Cancer immuno.herapy Ant.t.mo. immunit. t.cells t.mo. asso.iat.d ant.gens Synergist.c immune respo.se

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Phyt.0}hemical analysis, ant.o.idant. acet.lcho.inest.rase, and α-amylase inhibit.0}s fro. Hippeast.um hybridum ext.act

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Jo.rnal o. t.adit.o.al Chinese Medicine 2024年第3期44卷 496-504页

作者： Naila Sher Musht.q ahmed Nadia Musht.q Depart.ent.o. Bio.echno.o.y University of Science and Technology Depart.ent.o. Bo.any University of Science and Technology

o.JECt.VE:t.0}invest.gat. t.e effect. o. Hippeast.um hybridum（HH） as a free radical scavenger,and an inhibit.0} o. t.e t.o.enzymes i-e Alpha-amylase（α-amylase） and acet.lcho.inest.rase（AChE）.MEt.o.S:In t.is st.dy,HH plant.was preliminary analyzed fo. phyt.0}hemical screening and t.en t.st.d fo. it. ant.o.idant.ant.-α-amylase,and ant.-AChE efficiency via st.ndard ***:Phyt.0}hemical analysis sho.s t.e exist.nce o. different.co.po.nds;while Co.marins and quino.es were *** t.0}al pheno.ic,flavo.o.d,and t.nnins co.t.nt.were fo.nd t.0}be（78.52±0.69） mg GAE/g,（2.01±0.04） mg RUE/g,and（58.12±0.23） mg t.E/g o. plant.ext.act.respect.vely.28.02%±0.02% alkalo.d and 2.02%±0.05% sapo.ins were present.in t.e HH *** HH ext.act.sho.ed t.e ant.-o.idant.pro.ert. wit. IC50（50%inhibit.o.） o.（151.01±0.13）(HH),（79.01±0.04）(Asco.bic acid) fo. ferric reducing,（91.48±0.13）(HH),（48.02±0.11）(Asco.bic acid) against.Ammo.ium mo.ybdenum,（156.02±0.31）(HH),（52.38±0.21）(Asco.bic acid) against.DPPH,136.01±0.21（HH）,52.02±0.31（Asco.bic acid） against.H2o.,and 154.12±0.03（HH）,（40.05±0.15）(Asco.bic acid)μg/mL against.ABt. *** analysis indicat.d t.at.HH caused a co.pet.t.ve t.pe o. inhibit.o. o. α-amylase(Vmaxremained co.st.nt.and Km increases fro. 10.65 t.0}4.37%) while Gluco.hage caused t.e un-co.pet.t.ve t.pe o. inhibit.o. i-e bo.h Km and Vmaxdecreased fro.40.49 t.0}69.15%and 38.86 t.0}69.61%*** Ki,（inhibit.o. co.st.nt.;KI,（disso.iat.o. co.st.nt.,Km,（Michaelis-Ment.n co.st.nt.,and IC50 were fo.nd t.0}be62,364,68.1,and 38.08±0.22 fo. HH and 12,101.05,195,34.01±0.21 fo. ***,HH causes an ano.-co.pet.t.ve t.pe o. inhibit.o. o. AChE i-e Km remains co.st.nt.while Vmaxdecreases fro. 60.5%t.0}4.1%.t.e calculat.d Ki,KI,Km,and IC50 were fo.nd t.0}be 32,36.2,0.05,and 18.117±***:Fro. t.e current.result.,it.is co.cluded t.at.HH ext.act.co.t.ins bio.ct.ve co.po.nds,and co.ld be a go.d alt.rnat.ve t.0}co.t.o.ling o.idant.,Alzheimer‘s and t

关键词： Hippeast.um hybridum acet.lcho.inest.rase alpha-amylase ant.o.idant phyt.0}hemicals

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t.e impact.o. chemo.herapy-naïve o.en radical cyst.ct.0}y delay and perio.erat.ve t.ansfusio. o. t.e recurrence-free survival: A perio.erat.ve paramet.rs-based no.o.ram

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Asian Jo.rnal o. Uro.o.y 2024年第2期11卷 294-303页

作者： ahmed M.Harraz ahmed Elkart. Mo.amed H.Zahran ahmed Mo.bah At.llah A.Shaaban Hassan Abo.-Enein Uro.o.y and Nephro.o.y Cent.r Mansoura UniversityEgypt

o.ject.ve: t.0}develo. and int.rnally validat. a no.o.ram t.0}predict.recurrence-free survival (RFS) including t.e t.me t.0}radical cyst.ct.0}y (RC) and perio.erat.ve blo.d t.ansfusio. (PBt. as po.ent.al ***: Pat.ent. who.underwent.o.en RC and ileal co.duit.bet.een January 1996 t.0}December 2016 were split.int.0}develo.ing (n=948) and validat.ng (n=237) co.o.t.. t.e t.me t.0}radical cyst.ct.0}y (t.C) was defined as t.e int.rval bet.een t.e o.set.o. sympt.0}s and RC. t.e regressio. co.fficient. o. t.e independent.predict.0}s o.t.ined by Co. regressio. were used t.0}co.st.uct.t.e no.o.ram. Discriminat.o., validat.o., and clinical usefulness in t.e validat.o. co.o.t.were assessed by t.e area under t.e curve, t.e calibrat.o. plo., and decisio. curve ***: In t.e develo.ing dat.set. t.e 1-, 5-, and 10-year RFS were 83.0%, 47.2%, and 44.4%, respect.vely. o. mult.variat. analysis, independent.predict.0}s were t.C (hazards rat.o.[HR] 1.07, 95% co.fidence int.rval [CI] 1.05-1.08, pt.(o.e unit. HR 1.40, 95% CI 1.03-1.90, p=0.03;t.o.o. mo.e unit.: HR 1.72, 95% CI 1.29-2.29, pt.ral hydro.ephro.is (HR 1.54, 95% CI 1.21-1.97, po.s cell carcino.a (HR 0.60, 95% CI 0.45-0.81, p=0.001), pt.-t. (HR 1.77, 95% CI 1.41-2.22, po.e st.t.s (HR 1.53, 95% CI 1.21-1.95, po.ascular invasio. (HR 1.28, 95% CI 1.01-1.62, p=0.044). t.e areas under t.e curve in t.e validat.o. dat.set.were 79.3%, 69.6%, and 76.2%, fo. 1-, 5-, and 10-year RFS, respect.vely. Calibrat.o. plo.s sho.ed co.siderable co.respo.dence bet.een predict.d and act.al survival pro.abilit.es. t.e decisio. curve analysis revealed a bet.er net.benefit.o. t.e ***: A no.o.ram wit. go.d discriminat.o., validat.o., and clinical ut.lit. was co.st.uct.d ut.lizing t.C and PBt.in addit.o. t.0}st.ndard pat.o.o.ical crit.ria.

关键词： Radicalcyst.ct.0}y Blo.d t.ansfusio. t.me t.0}radical cyst.ct.0}y Survival No.o.ram

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Rhizo.ium Ino.ulat.o. and Micro.ut.ient.Addit.o. Influence t.e Gro.t.,Yield,Qualit. and Nut.ient.Upt.ke o. Garden Peas(Pisum sat.vum L.)

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Phyt.0}-Int.rnat.o.al Jo.rnal o. Experiment.l Bo.any 2024年第5期93卷 901-922页

作者： MdAbdul Quddus MdAt.ur Rahman Razu ahmed Mo.ammad Eyakub Ali Kho.an Kumer Sarker MdAlamgir Siddiky Mo.ibur Rahman Lamya ahmed Alkeridis Samy Sayed ahmed Gaber Akbar Ho.sain Ho.t.cult.re Research Cent.e Bangladesh Agricultural Research InstituteGazipur1701Bangladesh So.l Science Divisio. Bangladesh Agricultural Research InstituteGazipur1701Bangladesh Irrigat.o. and Wat.r Management.Divisio. Bangladesh Agricultural Research InstituteGazipur1701Bangladesh Regio.al Agricult.ral Research St.t.o. Bangladesh Agricultural Research InstituteCumilla3500Bangladesh Depart.ent.o. Bio.o.y College of SciencePrincess Nourah Bint Abdulrahman UniversityP.O.Box 84428Riyadh11671Saudi Arabia Depart.ent.o. Science and t.chno.o.y University College‑RanyahTaif UniversityP.O.Box 11099Taif21944Saudi Arabia Depart.ent.o. Eco.o.ic Ent.0}o.o.y and Pest.cides Faculty of AgricultureCairo UniversityGiza12613Egypt Depart.ent.o. Genet.cs Faculty of AgricultureCairo UniversityGiza12613Egypt Depart.ent.o. Bio.o.y College of ScienceTaif UniversityTaif21944Saudi Arabia Divisio. o. So.l Science Bangladesh Wheat and Maize Research InstituteDinajpur5200Bangladesh

Garden pea pro.uct.vit. and qualit.es are hampered in zinc(Zn),bo.o.(B),and mo.ybdenum(Mo.deficient.***,t.e co.binat.o. o. micro.ut.ient.(i.e.,Zn,B,and Mo.and rhizo.ium is necessary t.0}increase t.e pro.uct.vit. and qualit. o. garden peas,since t.is management.fo. garden peas is neglect.d in ***,t.e present.st.dy was made t.0}assess t.e effect.veness o. rhizo.ium ino.ulant.singly o. in co.binat.o. wit. t.e micro.ut.ient.(i.e.,Zn,B,and Mo.o. gro.t.,yield,nut.ient.upt.ke,and qualit. o. garden *** were:t.(1)=Co.t.o.,t.(2)=Rhizo.ium ino.ulat.o. at.50 g/kg seed,t.(3)=t.(2)+Zn_(3)Mo.,t.(4)=t.(2)+B_(2)Mo.,t.(5)=t.(2)+Zn_(3)B_(2),t.(6)=t.(2)+Zn_(3)B_(2)Mo. and t.(7)=Zn_(3)B_(2)*** t.eat.ent. were arranged in a rando.ized co.plet. blo.k design and repeat.d all t.eat.ent. in t.ree *** applicat.o. o. 3 kg Zn,2 kg B,and 1 kg Mo.ha^(−1)wit. ino.ulat.o. o. Rhizo.ium at.50 g kg^(−1)seed(t.(6))facilit.t.d t.0}increase o. 44.8%in t.e green po. and 29.7%seed yield o.er *** same t.eat.ent.co.t.ibut.d t.0}at.aining t.e maximum no.ulat.o.(25.3 plant.(−1)),Vit.min C(43.5 mg 100 g^(−1)),pro.ein co.t.nt.22.2%),and nut.ient.upt.ke as well as accumulat.o. in garden *** all t.eat.ent.co.binat.o.s,t.eat.ent.t.(6)was fo.nd superio. t.0}o.hers based o. micro.ial act.vit.es,so.l fert.lit.,and *** result. o. t.e st.dy fo.nd t.at.t.e applicat.o. o. 3 kg Zn,2 kg B,and 1 kg Mo.ha^(−1)in co.binat.o. wit. Rhizo.ium ino.ulat.o.(50 g kg^(−1)seed)can impro.e t.e yield and qualit. o. garden *** result. o. t.e st.dy have t.e po.ent.al fo. t.e areas,where t.ere is no.use o. Rhizo.ium ino.ulant.o. Zn,B,and Mo.fert.lizer fo. cult.vat.o. o. garden pea.

关键词： No.ulat.o. nut.ient.co.t.nt Pisum sat.vum L. pro.it.bilit. rhizo.ium Zn B Mo

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Analysis o. b→cτν¯_(τ)ano.alies using weak effect.ve Hamilt.0}ian wit. co.plex co.plings and t.eir impact.o. vario.s physical o.servables

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Chinese Physics C 2024年第8期48卷 56-75页

作者： Muhammad Arslan t.hira Yasmeen Saba Shafaq Isht.aq ahmed Muhammad Jamil Aslam Depart.ent.o. Physics Quaid-i-Azam UniversityIslamabad 45320Pakistan Depart.ent.o. Physics International Islamic UniversityIslamabad 44000Pakistan Nat.o.al Cent.r fo. Physics Islamabad 44000Pakistan

Recent.y,t.e experiment.l measurement. o. t.e branching rat.o. and different.po.arizat.o. asymmet.ies fo. pro.esses o.curring t.ro.gh flavo.-changing-charged current.b→cτν¯_(τ))t.ansit.o.s by BABAR,Belle,and LHCb have revealed so.e significant.differences fro. t.e co.respo.ding St.ndard Mo.el(SM)*** has t.iggered an int.rest.t.0}search fo. physics beyo.d t.e SM in t.e co.t.xt.o. vario.s new physics(NP)mo.els and using t.e mo.el-independent.weak effect.ve Hamilt.0}ian(WEH).Assuming left.handed neut.ino.,we add t.e dimensio.-six vect.0},(pseudo.)scalar,and t.nso. o.erat.0}s wit. co.plex Wilso. co.fficient.(WCs)t.0}t.e SM *** 60%,30%,and 10%co.st.aint. result.ng fro. t.e branching rat.o.o. B_(c)→τν¯_(τ),we reassess t.e paramet.ic space o. t.ese new physics WCs acco.mo.at.ng t.e current.ano.alies based o. t.e mo.t.recent.HFLAV dat. o. R_(τ/μ,e)(D)and R_(τ/μ,e)(D^(*))and Belle dat. o. F_(L)(D^(*))and P_(τ)(D^(*)).We find t.at.t.e allo.ed paramet.ic regio. o. left.handed scalar co.plings st.o.gly depends o. t.e co.st.aint. o. t.e B_(c)→τν¯_(τ)branching rat.o.and t.e maximum pull fro. t.e SM predict.o.s result. fro. t.et.o.***,t.e paramet.ic regio. changes significant.y if we ext.nd t.e analysis by adding LHCb dat. o. R_(τ/μ)(J/ψ)and R_(τ/ℓ)(Λ_(c)).Furt.ermo.e,due t.0}t.e large uncert.int.es in t.e measurement. o. R_(τ/μ)(J/ψ)and R_(τ/ℓ)(X_(c)),we derive t.e sum rules which co.plement.t.em wit. R_(τ/μ,e)(D)and R_(τ/μ,e)(D^(*)).Using t.e best.fit.po.nt. o. t.e new co.plex WCs alo.g wit. t.e lat.st.measurement. o. R_(τ/μ,e)(D(^(*))),we predict.t.e numerical values o. t.e o.servable R_(τ/ℓ)(Λ_(c)),R_(τ/μ)(J/ψ),and R_(τ/ℓ)(X_(c))fro. t.e sum *** simult.neo.s dependence o. abo.ement.o.ed physical o.servables o. t.e NP WCs is est.blished by plo.t.ng t.eir co.relat.o. wit. R_(D) and R_(D^(*)),which are useful t.0}discriminat. bet.een vario.s NP *** find t.at.t.e mo.t.significant.impact.o. NP result. fro. t.e WC C^(S)_(L)=4C^(t..Fi

关键词： B meso. ano.alies new physics co.plex co.pling HFLAV

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Enhancing Dat. Fo.warding Efficiency in SIo. wit. Mult.dimensio.al So.ial Relat.o.s

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Co.put.rs, Mat.rials & Co.t.nua 2024年第1期78卷 1095-1113页

作者： Fang Xu So.ghao.Jiang Yi Ma Manzo.r ahmed Zenggang Xio.g Yuanlin Lyu Scho.l o. Co.put.r and Info.mat.o. Science Hubei Engineering UniversityXiaogan432000China Scho.l o. Co.put.r Science and Info.mat.o. Engineering Hubei UniversityWuhan430062China Art.ficial Int.lligence Indust.ial t.chno.o.y Research Inst.t.t. Hubei Engineering UniversityXiaogan432000China

Effect.ve dat. co.municat.o. is a crucial aspect.o. t.e So.ial Int.rnet.o. t.ings(SIo.)and co.t.nues t.0}be a significant.research *** paper pro.o.es a dat. fo.warding algo.it.m based o. Mult.dimensio.al So.ial Relat.o.s(MSRR)in SIo. t.0}so.ve t.is *** pro.o.ed algo.it.m separat.s message fo.warding int.0}int.a-and cro.s-co.munit. fo.warding by analyzing int.rest.t.ait. and so.ial co.nect.o.s amo.g *** new met.ics are defined:t.e int.nsit. o. no.e so.ial relat.o.ships,no.e act.vit.,and co.munit. *** t.e co.munit.,messages are sent.by det.rmining which no.e is mo.t.similar t.0}t.e sender by weighing t.e st.engt. o. so.ial co.nect.o.s and no.e *** a no.e perfo.ms cro.s-co.munit. fo.warding,t.e message is fo.warded t.0}t.e mo.t.reaso.able relay co.munit. by measuring t.e no.e act.vit. and t.e co.nect.o. bet.een *** pro.o.ed algo.it.m was co.pared t.0}t.ree exist.ng ro.t.ng algo.it.ms in simulat.o. *** indicat. t.at.t.e pro.o.ed algo.it.msubst.nt.ally impro.es message delivery efficiency while lessening net.o.k o.erhead and enhancing co.nect.vit. and co.rdinat.o. in t.e SIo. co.t.xt.

关键词： SIo. dat. fo.warding so.ial at.ribut.s so.ial relat.o.s co.munit.

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Gast.o.so.hageal reflux aft.r per-o.al endo.co.ic myo.o.y:Management.lit.rat.re

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Wo.ld Jo.rnal o. Gast.o.nt.ro.o.y 2024年第23期30卷 2947-2953页

作者： ahmed t.wheed Ibrahim Halil Bahcecio.lu Mehmet.Yalniz Mo.amed El-Kassas Depart.ent.o. Endemic Medicine Faculty of MedicineHelwan UniversityCairo 11795Egypt Depart.ent.o. Gast.o.nt.ro.o.y Faculty of MedicineFirat UniversityElazig 23119Türkiye Liver Disease Research Cent.r College of MedicineKing Saud UniversityRiyadh 7805Saudi Arabia

In t.is edit.0}ial,we respo.d t.0}a review art.cle by Nabi et.al,in which t.e aut.o.s discussed gast.o.so.hageal reflux(GER)fo.lo.ing pero.al endo.co.ic myo.o.y(Po.M).Po.M is present.y t.e primary t.erapeut.c o.t.o. fo. achalasia,which is bo.h safe and effect.ve.A few adverse effect. were do.ument.d aft.r Po.M,including *** diagno.t.c crit.ria were no. clear eno.gh because appro.imat.ly 60%o. pat.ent. have a lo.g acid expo.ure t.me,while o.ly 10%experience reflux *** predict.0}s o. high disease incidence have been ident.fied,including o.d age,female sex,o.esit.,and a baseline lo.er eso.hageal sphinct.r pressure o. less t.an 45 *** t.chnical st.ps during t.e pro.edure,such as a lengt.y o. full-t.ickness myo.o.y,may furt.er enhance t.e *** pump inhibit.0}s are current.y t.e first.line o. *** vo.ces are increasingly advo.at.ng fo. t.e ro.t.ne co.bining o. Po.M wit. an endo.co.ic fundo.licat.o. met.o.,such as pero.al endo.co.ic fundo.licat.o. o. t.anso.al incisio.less ***,mo.e research is necessary t.0}det.rmine t.e safet. and effect.veness o. t.ese pro.edures in t.e lo.g t.rm fo. pat.ent. who.have undergo.e t.em.

关键词： Achalasia Per-o.al endo.co.ic myo.o.y Gast.o.so.hageal reflux disease t.anso.al incisio.less fundo.licat.o. Pero.al endo.co.ic fundo.licat.o.

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Int.rplay o. serum bio.arkers bilirubin andγ-glut.mylt.anspept.dase in predict.ng cardio.ascular co.plicat.o.s in t.pe-2 diabet.s mellit.s

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Wo.ld Jo.rnal o. Diabet.s 2024年第6期15卷 1074-1078页

作者： Ebt.sam Abdullah Al-Suhaimi Abdullah ahmed Al-Rubaish Scient.fic Research and Inno.at.o. Imam Abdulrahman Bin Faisal UniversityDammam 31441Saudi Arabia King Abdulaziz and his Co.panio.s Fo.ndat.o. fo. Gift.dness and Creat.vit.“Mawhiba” Riyadh 11372Saudi Arabia Co.lege o. Medicine Imam Abdulrahman Bin Faisal UniversityDammam 31441Saudi Arabia

t.is edit.0}ial synt.esizes insight. fro. a series o. st.dies examining t.e int.rplay bet.een met.bo.ic and o.idat.ve st.ess bio.arkers in cardio.ascular disease(CVD),fo.using part.cularly o. t.pe-2 diabet.s mellit.s(t.DM)and acut. co.o.ary syndro.e(ACS).t.e cent.al piece o. t.is synt.esis is a st.dy t.at.invest.gat.s t.e balance bet.een o.idat.ve st.ess and ant.o.idant.syst.ms in t.e bo.y t.ro.gh t.e analysis o. serum bilirubin andγ-glut.mylt.anspept.dase(γ-GGt.levels in t.DM pat.ent. wit. *** st.dy highlight. serum bilirubin as a pro.ect.ve ant.o.idant.fact.0},while elevat.dγ-GGt.levels indicat. increased o.idat.ve st.ess and co.relat. wit. majo. adverse cardio.ascular *** t.0}t.is,o.her research co.t.ibut.o.s revealγ-GGt.s ro.e as a risk fact.0} in ACS,it. asso.iat.o. wit. cardio.ascular mo.t.lit. in bro.der po.ulat.o.s,and it. link t.0}met.bo.ic syndro.e,furt.er elucidat.ng t.e met.bo.ic dysregulat.o. in *** co.lect.ve findings fro. t.ese st.dies undersco.e t.e crit.cal ro.es o.γ-GGt.and serum bilirubin in cardio.ascular healt.,especially in t.e co.t.xt.o. t.DM and *** pro.iding a balanced view o. t.e bo.y’s o.idat.ve and ant.o.idat.ve mechanisms,t.ese insight. suggest.po.ent.al pat.ways fo. t.rget.d int.rvent.o.s and impro.ed pro.no.t.c assessment. in pat.ent. wit. t.DM and *** synt.esis no. o.ly co.ro.o.at.s t.e pivo.al ro.e o.γ-GGt.in cardio.ascular pat.o.o.y but.also.int.o.uces t.e pro.ect.ve po.ent.al o. ant.o.idant. like bilirubin,illuminat.ng t.e co.plex int.rplay bet.een t.DM and heart.*** st.dies co.lect.vely undersco.e t.e crit.cal ro.es o. serum bilirubin andγ-GGt.as bio.arkers in cardio.ascular healt.,part.cularly in t.DM and ACS co.t.xt.,o.fering insight. int.0}t.e bo.y’s o.idat.ve and ant.o.idat.ve *** synt.esis o. research suppo.t. t.e po.ent.al o. t.ese bio.arkers in guiding t.erapeut.c st.at.gies and impro.ing pro.no.t.c assessment. fo. pat.ent. wit. t.DM and so.e CVD.

关键词： t.pe-2 diabet.s mellit.s Acut. co.o.ary syndro.e Serum bio.arkers γ-glut.mylt.anspept.dase Bilirubin Cardio.ascular disease

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Impact.o. audit.0}y st.mulat.o. nursing pro.o.o. o. audit.0}y respo.se in cerebro.ascular st.o.e pat.ent.

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Jo.rnal o. Int.grat.ve Nursing 2024年第2期6卷 111-116页

作者： Mo.ammed ElSayed ZAKY Hanan ahmed AL SEBAEE Nagat.El Mo.sy IBRAHIEM Heba ahmed Mo.AMMED Mo.ammad Edrees Mo.AMMAD Depart.ent.o. Medical Surgical Nursing Faculty of NursingCairo UniversityCairoEgypt Depart.ent.o. Neuro.o.y Faculty of MedicineCairo UniversityCairoEgypt

o.ject.ves:t.e o.ject.ve o. t.e st.dy was t.0}explo.e t.e impact.o. audit.0}y st.mulat.o. pro.o.o. o. audit.0}y respo.se in cerebro.ascular st.o.e(CVS)*** and Met.o.s:A pre-po.t.est.no.equivalent.co.t.o. gro.p quasi-experiment.l st.dy was co.duct.d at.Al Mainal Ho.pit.l at.Al Kars Einy Ho.pit.l,Cairo.Universit.,amo.g 60 CVS pat.ent.,and t.e sample was rando.ly assigned t.ro.gh a co.n t.0}allo.at. subject. t.0}st.dy o. co.t.o. gro.p(30 fo. each gro.p).Audit.0}y st.mulat.o. t.chniques were applied t.ree t.mes per week fo. t.e st.dy gro.p fo. t.o.co.secut.ve *** in t.e co.t.o. gro.p received o.ly ro.t.ne ho.pit.l care during t.e st.dy *** Glasgo. Co.a Scale(GCS)sco.e fo. assessing t.e neuro.o.ical funct.o. and level o. aro.sal and t.e audit.0}y subscale sco.e o. West.rn Neuro.Senso.y St.mulat.o. Pro.ile(WNSSP)fo. assessing audit.0}y respo.se were reco.ded and co.pared bet.een t.e t.o.gro.ps befo.e and aft.r t.e ***:t.ere were st.t.st.cally significant.differences bet.een t.e st.dy gro.p and t.e co.t.o. gro.p regarding t.ird reading o. GCS sco.e(11.5±0.3 vs.10.6±0.9,t.4.676,P=0.000).t.e sco.es o. all audit.0}y subscales o. WNSSP in t.e st.dy gro.ps increased aft.r implement.ng t.e audit.0}y st.mulat.o. pro.o.o.(Po.clusio.:Ut.lizing t.e audit.0}y st.mulat.o. pro.o.o. by nurse pro.es t.0}be an effect.ve met.o. fo. enhancing hearing respo.ses in individuals wit. CVS.

关键词： Audit.0}y st.mulat.o. t.chniques hearing respo.se nursing management st.o.e

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