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Effects of positive end-expiratory pressure on intracranial pressure,cerebral perfusion pressure,and brain oxygenation in acute brain injury:Friend or foe?A scoping review

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Journal of Intensive Medicine 2024年第2期4卷 247-260页

作者： Greta Zunino Denise Battaglini Daniel agustin Godoy IRCCS Ospedale Policlinico San Martino GenovaItaly Dipartimento di Scienze Diagnostiche e Chirurgiche Integrate Universitàdegli Studi di GenovaGenovaItaly Neurointensive Care Unit Sanatorio PasteurCatamarcaArgentina

Background Patients with acute brain injury(ABI)are a peculiar population because ABI does not only affect the brain but also other organs such as the lungs,as theorized in brain–lung crosstalk *** patients often require mechanical ventilation(MV)to avoid the complications of impaired respiratory function that can follow ABI;MV should be settled with meticulousness owing to its effects on the intracranial compartment,especially regarding positive end-expiratory pressure(PEEP).This scoping review aimed to(1)describe the physiological basis and mechanisms related to the effects of PEEP in ABI;(2)examine how clinical research is conducted on this topic;(3)identify methods for setting PEEP in ABI;and(4)investigate the impact of the application of PEEP in ABI on the *** The five-stage paradigm devised by Peters et *** expanded by Arksey and O'Malley,Levac et al.,and the Joanna Briggs Institute was used for *** also adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses(PRISMA)extension *** criteria:we compiled all scientific data from peer-reviewed journals and studies that discussed the application of PEEP and its impact on intracranial pressure,cerebral perfusion pressure,and brain oxygenation in adult patients with *** criteria:studies that only examined a pediatric patient group(those under the age of 18),experiments conducted solely on animals;studies without intracranial pressure and/or cerebral perfusion pressure determinations,and studies with incomplete *** authors searched and screened for inclusion in papers published up to July 2023 using the PubMed-indexed online *** were presented in narrative and tubular *** The initial search yielded 330 references on the application of PEEP in ABI,of which 36 met our inclusion *** has recognized beneficial effects on gas exchange,but it produces hemodynamic changes that should be predicted to avoi

关键词： Acute brain injury Mechanical ventilation Positive end-expiratory pressure Intracranial pressure Brain-lung crosstalk Multimodal monitoring

The Influence of Company Performance on Company Value(K-Pop Entertainment Company Registered on *** South Korea 2018-2022)

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Economics World 2024年第3期11卷 156-164页

作者： Ryana Putri agustin Eddy Winarso Jenderal Achmad Yani University CimahiBandungIndonesia

A well-managed company is a company that maximizes the value of its company,which is aimed at achieving maximum profits for *** research aims to determine and analyze the influence of company size,profitability,and financial leverage on the value of companies listed on the South Korean Stock Exchange KOSPI *** population consists of 8 South Korean K-Pop entertainment companies registered on KOSPI *** sampling technique used was purposive sampling with a total sample of 8 companies and a 5-year observation *** that 40 data were *** analysis technique is multiple linear *** results obtained show that partially company size has no significant effect on company value,profitability has a significant positive effect on company value,and financial leverage has a significant negative effect on company ***,simultaneously company size,profitability,and financial leverage influence company value.

关键词： company size profitability financial leverage company value

New Rotative Radiofrequency Technology: A Multicenter Retrospective Study on Efficacy and Safety

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Journal of Cosmetics, Dermatological Sciences and Applications 2024年第1期14卷 69-83页

作者： José Antonio Ferrández Martínez Gregorio Viera Mármol Fabrizio Vignoli Joanet Perera agustin Blanch Mara Suárez Alicia Robledo Jorge Reyna Vargas Lamas Sinclair Barcelona Spain Studio Vignoli Bologna Italy Clinica Perla Medic Alicante Spain Dr. agustin Blanch Clinica Barcelona Spain Intek Medical Technology S.L.U. Barcelona Spain

Background: Non-ablative radiofrequency (RF) technology is widely used for the treatment of signs of aging, skin laxity, localized fat and cellulite. However, many RF devices suffer from technical limitations that make the results highly dependent on the user’s experience or clinical limitations that compromise safety, efficacy and comfort. Objective: To evaluate the efficacy and safety of a novel semi-automatic non-ablative RF device for skin tightening, body shaping and cellulite reduction. Materials and methods: A retrospective multicenter study was performed using a novel rotative RF device with temperature and impedance control (Sculpt&Shape®, Sinclair, Spain). 58 subjects underwent a minimum of 4 treatments every 1-2 weeks. A total of 120 treatments (56.7% body and 43.3% facial) and 1034 sessions were performed. Efficacy was evaluated by 3 researchers using the Global Aesthetic Improvement Scale (GAIS) and anthropometric measurements were collected. Subject and practitioner satisfaction were recorded. Safety was evaluated by analyzing the perception of pain during the treatment and the side and adverse effects immediately after treatment and over the next 48 hours. Results: Between 25% and 50% improvement was achieved according to the GAIS. Statistically significant (p < 0.01) abdominal fold reduction of 5.1 mm and circumference reduction of 32.0 mm, 16.4 mm and 13.9 mm were recorded for the abdomen, legs and arms, respectively. 77.5% of subjects and 94.9% of practitioners were either satisfied or very satisfied. Minor adverse effects were found in 0.97% of the sessions. Conclusion: This novel semi-automatic rotative RF device has been found to provide treatments that are effective, safe and comfortable for both practitioners and subjects. .

关键词： Rotative Radiofrequency RF Cellulite Skin Tightening Body Shaping

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让中国文学保持与世界接轨

中国新闻发布（实务版） 2024年第4期 31-32页

作者：夏海明不详

我第一次到中国是2007年8月底。那时,我刚毕业不久,从来没有离开过家乡,更没有在国外生活的经验,选择去北京的某所大学读书可以说是一种探险,也是我一生中意义最大的经历之一。我大学读的是中西翻译和汉学研究专业,但那时我对中国文化... 详细信息

我第一次到中国是2007年8月底。那时,我刚毕业不久,从来没有离开过家乡,更没有在国外生活的经验,选择去北京的某所大学读书可以说是一种探险,也是我一生中意义最大的经历之一。我大学读的是中西翻译和汉学研究专业,但那时我对中国文化和中国国情的了解非常有限。当时决定到中国来,我的主要目标是进修汉语课程,实地提升我的中文水平,以及拓宽对中国各方面的了解。

关键词：汉学研究汉语课程中文水平读书中国国情

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中央银行数字货币的相关法律框架

中国金融 2024年第1期 24-25页

作者：奥古斯汀·卡斯滕斯柳十嘉国际清算银行中国人民银行湖南省分行

当前面临的重要工作是更新完善法律框架,以确保货币在数字背景下的合法性、隐私性、职业操守和可选择性中央银行数字货币的重要性在讨论法律问题之前,需要先研究一下中央银行数字货币的本质。中央银行的关键角色是为社会公众提供货币,... 详细信息

当前面临的重要工作是更新完善法律框架,以确保货币在数字背景下的合法性、隐私性、职业操守和可选择性中央银行数字货币的重要性在讨论法律问题之前,需要先研究一下中央银行数字货币的本质。中央银行的关键角色是为社会公众提供货币,目前主要通过现金和中央银行准备金的方式来实现。但在实践中,这些货币只占公众所用货币的一小部分,大部分货币是以银行存款的形式存放于商业银行。即便如此,中央银行在确保公众对货币的信任方面仍然发挥了关键作用。

关键词：中央银行数字货币银行存款商业银行职业操守法律框架隐私性准备金

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技术创新的小步前行和大步跨越

中国金融 2024年第14期 17-18页

作者：奥古斯汀·卡斯滕斯牟思思(译) 张赶(译) 王韬(译) 国际清算银行中国人民银行重庆市分行重庆国家金融科技认证中心

为规划真正连贯的未来金融体系愿景,我们必须借助高端技术来为高效的经济和金融体系,以及健全的治理和监管提供支撑技术和创新的力量不容小觑。订阅用户突破100万,流媒体播放平台奈飞(Netflix)花了三年半的时间,流媒体音乐服务平台Spot... 详细信息

为规划真正连贯的未来金融体系愿景,我们必须借助高端技术来为高效的经济和金融体系,以及健全的治理和监管提供支撑技术和创新的力量不容小觑。订阅用户突破100万,流媒体播放平台奈飞(Netflix)花了三年半的时间,流媒体音乐服务平台Spotify用了5个月,聊天机器人程序ChatGPT则是5天,而社交平台Threads仅用了一个小时。这些创新的数字平台均创造了前所未有的机会。当第一款智能手机问世时,没有人能预测到今天会涌现数百万个应用程序(App)。如果没有20世纪90年代中期研发出来的蓝牙技术,今天的智能手表、无线耳机以及可在手机和电视上播放的流媒体视频将无从谈起。技术应用加速改变了创新对社会的影响。

关键词：聊天机器人流媒体服务平台智能手表无线耳机数字平台蓝牙技术智能手机

Water evacuations in remote tourist regions: evaluating case studies from natural hazards in North Patagonian lakes, Argentina

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Journal of Mountain Science 2022年第6期19卷 1782-1807页

作者： SALGADO Pablo agustin VILLAROSA Gustavo BEIGT Debora OUTES Valeria IPATEC(Instituto Andino-Patagonico de Tecnologias Biologicas y Geoambientales) CONICET-UNCOAv.de los Pioneros 23508400 S.C.de BarilocheArgentina Centro Regional Uniuersitario Bariloche Universidad Nacional del ComahueQuintral 12508400 S.C.de BarilocheArgentina

The remote North Patagonian region is a sparsely populated territory and a world famous tourist destination located on the leeward side of the Andes Mountains. Recent disasters triggered by various types of geoenvironmental hazards(including volcanic eruptions, mass-wasting processes and extreme weather events) heavily disrupted ground transport networks in a region with already limited territorial accessibilities. All these catastrophes prompted the need to evacuate or assist a number of secluded visitors, locals and livestock extemporaneously on board of coastguards and tourist passenger-ships from the shores of the many glacial lakes that make up part of the regional attraction. Despite the recurrence of these types of events, water evacuations in the region continue to be spontaneous, improvised and hazardous procedures. This contribution reconstructs and assesses a number of recent local-scale cases of lake evacuations and assistances from a number of Patagonian urban centers, rural areas and tourist sites. For each case study, we systematically elaborated on the prime components of an evacuation process, which enabled us to recognize key achievements, failures and conditioning factors for managing emergencies via water transport, most of them inherent to the studied region. Some of the complexities to emerge from case studies referred to: complex hazard-related scenarios;limited ground-based accessibilities and risk of isolation;various inter-and intra-organizational issues, incidental to natural reserves and tourist regions;a wide range of particular demographic features;and the availability and vulnerability of water transport resources. We suggested fundamental and replicable recommendations for developing water evacuation plans, also identifying forthcoming problems to solve in order to improve the management of emergencies through this alternative means of transport.

关键词： Water transport Emergency management Accessibility problems Tourism activities Volcanic crises Mountain area

Applying machine learning techniques to predict laminar burning velocity for ammonia/hydrogen/air mixtures

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Energy and AI 2023年第3期13卷 207-218页

作者： Cihat Emre Ustun Mohammad Reza Herfatmanesh agustin Valera-Medina Amin Paykani School of Physics Engineering and Computer ScienceUniversity of HertfordshireHatfieldAL109ABUnited Kingdom College of Physical Sciences and Engineering Cardiff UniversityCardiffCF243AAUnited Kingdom

Ammonia utilisation in internal combustion engines has attracted wide interest due to the current trend toward decarbonisation,as ammonia is a zero-carbon fuel with different combustion properties to *** laminar burning velocity(LBV)is a fundamental property of fuels with a significant effect on the combustion processes and accurate calculations and measurements of the LBV over a wide range of fuel blends,pressures and flow conditions is a time-consuming,complicated *** main goal of the current study is to predict the LBV of NH_(3)/H_(2)/air mixtures using a hybrid machine learning(ML)approach based on a training dataset consisting of both the experimental LBV values and additional data obtained from numerical simulations with a detailed kinetic *** ML model training data is collected from existing experimental LBV in the literature for NH_(3)/H_(2)/air ***,synthetic data is generated using one-dimensional(1D)simulations to reduce data inhomogeneity and increase accuracy of the ML *** total,24 different ML algorithms are tested to find the best model both for the experimental and the hybrid *** results suggest that both Gaussian Process Regression(GPR)and Neural Networks(NNs)can be utilised to predict LBV of NH_(3)/H_(2)/air mixtures with reasonable *** hybrid ML model achieved a coefficient of determination of R^(2)=***,hybrid ML model hyperparameters are optimised to achieve a coefficient of determination of R^(2)=*** was also found that ML can speed up LBV computation from 9500 to 27000 times compared to 1D simulations with a reduced mechanism.

关键词： Machine learning Ammonia Hydrogen Laminar burning velocity Combustion

Dual Phase Renewable Fuel Combustion in an Atmospheric Gas Turbine Burner

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Journal of Thermal Science 2023年第3期32卷 1278-1291页

作者： AGWU Ogbonnaya RUNYON Jon GOKTEPE Burak CHONG TUNG Cheng NG Jo-Han GILES Anthony VALERA-MEDINA agustin School of Engineering Cardiff UniversityWales CF243AAUK China-UK Low Carbon College Shanghai Jiao Tong UniversityLin'gang 201306China Faculty of Engineering and Physical Sciences University of Southampton MalaysiaIskandar Puteri 79100Malaysia

Expanding the fuel flexibility of continuous combustion systems to include multiphase fuel combustion offers additional support to combat the problem of energy security and,potentially,environmental *** this study,apart from establishing stability limits and measuring post-combustion emissions,flames generated from simultaneous combustion of biodiesel and syngas were examined using C_(2)*and CH*chemiluminescence imaging to capture changes in the reaction *** proportion of syngas in the fuel mix was varied from 0 to 30%content(by energy contribution)while maintaining a total power output of 15 *** overall equivalence ratio was held at 0.7 in cases other than for determining the flammability *** results indicate a reduction of stability limits as gas proportion in fuel blend ***,chemiluminescence imaging of the two targeted species suggest a general reduction in reaction rate as well as reaction zone area and length with increase in gas ratio in the dual phase ***,emissions performance in the context of NOxand CO was investigated as liquid-to-gas ratios were ***,the study demonstrates the feasibility,limitations and potential benefits of multiphase renewable fuel combustion in a swirl-stabilised burner.

关键词： dual fuel gas turbine multiphase combustion