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Leishmaniasis in the Argentine Republic: Temporal and geographical distribution from 2013 to 2017

Asian Pacific Journal of Tropical Medicine 2019年第7期12卷 300-305页

作者： GermanóMaría J Salomón María C neira Gisela Lozano Esteban Mackern-Oberti Juan P Cargnelutti Diego E Consejo nacional de Investigaciones Científicas y Técnicas Centro Científico y Tecnológico de MendozaInstituto de Medicina y Biología Experimental de CuyoMendozaArgentina Universidad nacional de Cuyo Facultad de Ciencias Médicasárea de ParasitologíaMendozaArgentina Universidad Juan agust.n Maza Facultad de Ciencias Veterinarias y AmbientalesCentro de Investigación en Parasitología RegionalMendozaArgentina Universidad nacional de Cuyo Facultad de Ciencias MédicasInstituto de FisiologíaMendozaArgentina

Objective: To assess the temporal and geographical distribution of confirmed cases of cutaneous, mucocutaneous and visceral leishmaniasis in the Argentine Republic from 2013 to 2017. Methods: A retrospective study was carried out using data collected from the Integrated Surveillance Bulletin database of the national System of Health Surveillance. Confirmed cases of cutaneous, mucocutaneous and visceral leishmaniasis up to the 52 nd epidemiological week of each year was included. Results: In the 5 years period, 1 295 confirmed leishmaniasis cases were reported in the Argentine Republic. One thousand twenty-eight(1 028) cases corresponded to cutaneous leishmaniasis(87.10%), being the most common type of leishmaniasis. Mucocutaneous leishmaniasis was in the second place in the country with 115 cases reported, mostly in the northwest and northeast regions. A total of 52 individuals with visceral leishmaniasis were identified and Misiones Province was the most affected. Conclusions: It is important to analyze the temporal and geographical distribution of leishmaniasis in order to provide an adequate management and surveillance.

关键词： Leishmaniasis Epidemiology Argentine Republic Temporal distribution Geographical distribution

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Areas with Potential for Commercial Timber Plantations of Enterolobium cyclocarpum (Jacq.) Griseb. in Michoacán, México

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Open Journal of Forestry（林学期刊） 2016年第5期

作者： HipólitoJesúsMuñoz-Flores J.TrinidadSáenz-Reyes agust.nRueda-Sánchez

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Optimized combinations of statins and azoles against Acanthamoeba trophozoites and cysts in vitro

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Asian Pacific Journal of Tropical Medicine 2019年第6期12卷 283-287页

作者： Ines Sifaoui Carmen M Martín-navarro Atteneri López-Arencibia María Reyes-Batlle Basilio Valladares JoséE.Pinero Sutherland K Maciver Jacob Lorenzo-Morales University Institute of Tropical Diseases and Public Health of the Canary Islands University of La LagunaCanary IslandsSpain Centre for Integrative Physiology Biomedical SciencesEdinburgh Medical SchoolUniversity of EdinburghScotlandUK

Objective: To evaluate the combination of several statins(atorvastatin, fluvastatin and simvastatin) and azoles(voriconazole, posaconazole and itraconazole) against Acanthamoeba spp. Methods: The efficiency of the different drug combinations against the trophozoite stage of different Acanthamoeba strains were evaluated by Alamar Blue assay. Effect on the cyst stage was observed by inverted microscope. Cytotoxicity of combinations of azoles and statins was evaluated by measuring the release of lactate dehydrogenase from a murine macrophage cell line. Results: Combinations of any of the tested statins and voriconazole or posaconazole were more efficient in inhibiting Acanthamoeba compared to statins or azoles individually. The drug combinations at the combined inhibitory concentrations 50% showed lower toxicity compared to that of the compounds ***: The combinations of statins together with voriconazole and posaconazole are more efficient than these drugs alone, and these combinations have lower cytotoxicity in mammalian cell lines.

关键词： Keratitis Voriconazole Posaconazole Atorvastatin Fluvastatin Simvastatin

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Cooperative Virus-Virus Interactions:An Evolutionary Perspective

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BioDesign Research 2022年第1期2022卷 111-123页

作者： Ernesto Segredo-Otero Rafael Sanjuán Institute for Integrative Systems Biology(I2SysBio) Consejo Superior de Investigaciones Científicas-Universitat de ValènciaC/Catedrático Agustín Escardino 946980 PaternaValènciaSpain

Despite extensive evidence of virus-virus interactions,not much is known about their biological ***,virusvirusinteractions could have evolved as a form of cooperation or simply be a by-product of other ***,we review anddiscuss different types of virus-virus interactions from the point of view of social evolution,which provides a well-establishedframework for interpreting the fitness costs and benefits of such *** also classify interactions according to theirmechanisms of action and speculate on their evolutionary *** in any other biological system,the evolutionarystability of viral cooperation critically requires cheaters to be excluded from cooperative *** discuss how cheaterviruses exploit cooperative traits and how viral populations are able to counteract this maladaptive process.

关键词： interpreting spite classify

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Effect of electromagnetic interaction on microstructure and corrosion resistance of 7075 aluminium alloy during modified indirect electric arc welding process

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Transactions of nonferrous Metals Society of China 2019年第3期29卷 473-484页

作者： J. S. REYnA-MOnTOYA M. A. GARCIA-REnTERIA V. L. CRUZ-HERnAnDEZ F. F. CURIEL-LOPEZ L. R. DZIB-PEREZ L. A. FALCOn-FRAnCO Faculty of Metallurgy Autonomous University of CoahuilaCarretera 57 Km. 5 CP 25720 Monclova Coahuila México Instituto de Investigación en Metalurgia y Materiales Universidad Michoacana de San Nicolás de Hidalgo A. P. 888 CP 58030 Morelia Michoacán México Centre for Corrosion Research Autonomous University of CampecheAv. Agustín Melgar s/n Col. Buenavista CP 24039 Campeche Cam México

The effects of applying an electromagnetic interaction of low intensity (EMILI) on the microstructure and corrosion resistance of 7075-T651 Al alloy plates (13 mm in thickness) during modified indirect electric arc (MIEA) welding were investigated. The welding process was conducted in a single pass with a heat input of ~1.5 kJ/mm. The microstructural observations of the welds were correlated with the effect of EMILI on the local mechanical properties and the corrosion resistance in natural seawater by means of microhardness measurements and electrochemical impedance spectroscopy, respectively. Microstructural characterization of the welds revealed a grain refinement in the weld metal due to the electromagnetic stirring induced by EMILI of 3 mT during welding. In addition, observations in the scanning electron microscope showed that the precipitation of Cu-rich phases and segregation of eutectics were reduced in the heat affected zone (HAZ) also as an effect of EMILI. The high corrosion dissolution of the 7075-T651 welds in natural seawater and the extent of overaging in the HAZ were reduced when welding with EMILI of 3 mT. Thus, EMILI along with the MIEA technique may lead to welded joints with better microstructural characteristics, improved mechanical properties in the HAZ and reduced electrochemical activity.

关键词： 7075-T651 Al alloy modified indirect arc welding microstructural characterization corrosion resistance electromagnetic interaction

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