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Biomaterials for spinal cord repair

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Neuroscience Bulletin 2013年第4期29卷 445-459页

作者： agnes E. Haggerty Martin oudega Departments of Bioengineering University of Pittsburgh Departments of the Center for the Neural Basis of Cognition University of Pittsburgh Departments of Physical Medicine and Rehabilitation University of Pittsburgh Departments of Neurobiology University of Pittsburgh

Spinal cord injury （SCI） results in permanent loss of function leading to often devastating personal, economic and social problems. A contributing factor to the permanence of SCI is that damaged axons do not regenerate, which prevents the re-establishment of axonal circuits involved in function. Many groups are working to develop treatments that address the lack of axon regeneration after SCI. The emergence of biomaterials for regeneration and increased collaboration between engineers, basic and translational scientists, and clinicians hold promise for the development of effective therapies for SCI. A plethora of biomaterials is available and has been tested in various models of SCI. Considering the clinical relevance of contusion injuries, we primarily focus on polymers that meet the specific criteria for addressing this type of injury. Biomaterials may provide structural support and/or serve as a delivery vehicle for factors to arrest growth inhibition and promote axonal growth. Designing materials to address the specific needs of the damaged central nervous system is crucial and possible with current technology. Here, we review the most prominent materials, their optimal characteristics, and their potential roles in repairing and regenerating damaged axons following SCI.

关键词： spinal cord injury axon regeneration biodegradable materials extracellular matrix proteins functionalrecovery growth factor guidance injury and repair spinal motor neuron

Preface to A Study of agnes Heller’s Thoughts on Aesthetic Modernity by Fu Qilin

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Comparative Literature:East & West 2007年第1期 57-59页

作者： agnes Heller New School for Social Research in New York

本文是阿格妮丝·赫勒为书稿《阿格妮丝·赫勒审美现代性思想研究》所写的序,肯定了此书从美学现代性角度考察其著述的新颖性与合法性,有助于帮助读者理解她的现代性理论、伦理学与历史哲学。赫勒在文中重新阐释了从现代美学起源到当代... 详细信息

本文是阿格妮丝·赫勒为书稿《阿格妮丝·赫勒审美现代性思想研究》所写的序,肯定了此书从美学现代性角度考察其著述的新颖性与合法性,有助于帮助读者理解她的现代性理论、伦理学与历史哲学。赫勒在文中重新阐释了从现代美学起源到当代的某些重要问题,也谈及其近年的美学与艺术转向。

关键词：赫勒现代美学现代性理论 Heller 历史哲学审美现代性 favorite familiar

Attention-deficit/hyperactivity disorder and suicide:A systematic review

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World Journal of Psychiatry 2017年第1期7卷 44-59页

作者： Judit Balazs agnes Kereszteny Vadaskert Child and Adolescent Psychiatry Hospital Institute of Psychology Eotvos Loránd University School of Ph.D. Studies Semmelweis University

AIM To investigate suicidality and attention-deficit/hyperactivity disorder(ADHD), this paper aims to systematically review the literature as an extension of previous *** We searched five databases(Ovid MEDLINE, Psychinfo, PubM ed, Scopus, Web of Science) with two categories of search terms:(1) suicide; suicidal; suicide behavior; suicide attempt; suicidal thought; and(2) ADHD. RESULTS The search resulted 26 articles. There is a positive association between ADHD and suicidality in both sexes and in all age groups. Comorbid disorders mediate between suicidality and ADHD. CONCLUSION Recognizing ADHD, comorbid conditions and suicidality is important in prevention.

关键词： Attention-deficit/hyperactivity disorder Suicide Systematic review

Geological applications using geospatial standards-an example from OneGeology-Europe and GeoSciML

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维普期刊数据库

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International Journal of Digital Earth 2010年第S01期3卷 31-49页

作者： John Laxton Jean-Jacques Serrano agnes Tellez-Arenas British Geological Survey Murchison HouseWest Main Rd.Edinburgh EH93LAUK BRGM 3 Avenue Claude-GuilleminBP 36009Orleans 45060France

The Geoscience Markup Language(GeoSciML)has been developed to enable the interchange of geoscience information,principally that portrayed on geological maps as well as boreholes.A GeoSciML testbed was developed both to test the implementation of the data model and its application in web *** OneGeology-Europe project aims to use the GeoSciML data model,and build on the experience of the GeoSciML testbed,in implementing a geoportal for a harmonised geological map of Europe at 1:1 million *** involves the integration of web services from 20 participating *** important objective of OneGeology-Europe is to contribute to Infrastructure for Spatial Information in the European Community(INSPIRE),both through the development of a geological data specification and the use of the INSPIRE technical *** and the OneGeology-Europe project are also steps towards incorporating geoscience data into a Digital *** the development of GeoSciML and the implementation of web services for GeoSciML and OneGeology-Europe,have followed a standards-based *** technical architecture comprises a geoportal providing access to a Catalogue Service for the Web for metadata describing both the data and services ***-Europe will provide bothWeb Map Services view andWeb Feature Services download services,which aim to be compliant with the INSPIRE implementing rules.

关键词： data exchange model web services spatial data standards INSPIRE digital earth geoinformatics geology

“Classical Realism” and the Problematic of Marxist Literary Criticism-An Examination of Wu Zuxiang's Review on Dream of the Red Chamber

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Frontiers of Literary Studies in China-Selected Publications from Chinese Universities 2019年第4期13卷 546-562页

作者： agnes Zhuo LIU Institute of Literature Chinese Academy of Social SciencesBeijing 100732China

The term of“Classical Realism”was derivate from the dominate discourse of realism and used for studies of Chinese ancient vernacular novels ever since *** Zuxiang took this term and organized his analysis of Dream of the Red Chamber with the Marxist literary ***'s adoption of realism principle might be defended as a strategic cover for that the discussion of literary skills would be labeled as bourgeois in that *** paper attempts to argue that the framework of Marxist literary criticism had indicated the transformation of scientific method of literature *** Wu's remark of Dream of the Red Chamber as the“great work of Classical Realism”is rather a conclusion from his consistent reflection on new literature after May Fourth,rather than the influence of ideological construction.

关键词： Classical Realism Wu Zuxiang Dream of the Red Chamber Marxist literary criticism

A comparison of single shot nanosecond and femtosecond polarization-resolved laser-induced breakdown spectroscopy of Al

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Chinese Physics B 2013年第1期22卷 273-277页

作者： Nakimana agnes 陶海岩郝作强孙长凯高勋林景全 School of Science Changchun University of Science and Technology

Aluminum samples have been analyzed by femtosecond polarization-resolved laser-induced breakdown spectroscopy （fs-PRLIBS）. We compare the obtained spectra with those obtained from nanosecond PRLIBS （ns-PRLIBS）. The main specific features of fs-PRLIBS are that a lower plasma temperature leads to a low level of continuum and no species are detected from the ambient gas. Furthermore, signals obtained by fs-PRLIBS show a higher stability than those of ns-PRLIBS. However, more elements are detected in the ns-PRLIBS spectra.

关键词： polarization-resolved laser-induced breakdown spectroscopy femtosecond laser nanosecond laser shielding

Lesion-induced changes of brevican expression in the perineuronal net of the superior vestibular nucleus

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Neural Regeneration Research 2022年第3期17卷 649-654页

作者： agnes Magyar Eva Racz Clara Matesz Ervin Wolf Peter Kiss Botond Gaal Pediatrics Clinic Faculty of MedicineUniversity of DebrecenDebrecenHungary Department of Anatomy Histology and EmbryologyFaculty of MedicineUniversity of DebrecenDebrecenHungary Division of Oral Anatomy Faculty of DentistryUniversity of DebrecenDebrecenHungary MTA-DE Neuroscience Research Group DebrecenHungary

Damage to the vestibular sense organs evokes static and dynamic deficits in the eye movements,posture and vegetative *** a shorter or longer period of time,the vestibular function is partially or completely restored via a series of processes such as modification in the efficacy of synaptic *** the plasticity of adult central nervous system is associated with the alteration of extracellular matrix,including its condensed form,the perineuronal net,we studied the changes of brevican expression in the perineuronal nets of the superior vestibular nucleus after unilateral labyrinth *** results demonstrated that the unilateral labyrinth lesion and subsequent compensation are accompanied by the changing of brevican staining pattern in the perineuronal nets of superior vestibular nucleus of the *** reduction of brevican in the perineuronal nets of superior vestibular nucleus may contribute to the vestibular plasticity by suspending the non-permissive role of brevican in the restoration of perineuronal net *** a transitory decrease,the brevican expression restored to the control level parallel to the partial restoration of impaired vestibular *** bilateral changing in the brevican expression supports the involvement of commissural vestibular fibers in the vestibular *** experimental procedures were approved by the 'University of Debrecen–Committee of Animal Welfare'(approval No.6/2017/DEMAB) and the 'Scientific Ethics Committee of Animal Experimentation'(approval ***/06/éLB/2270-10/2017;approved on June 6,2017).

关键词： brainstem brevican chondroitin sulfate proteoglycan extracellular matrix labyrinth lesion neural plasticity perineuronal net perisynaptic matrix vestibular compensation vestibular system

Environmental Impacts of the Yangtze Three Gorges Project: An Overview of the Chinese-German Research Cooperation

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Journal of Earth Science 2010年第6期21卷 817-823页

作者： Günter Subklew Julia Ulrich Leander Fürst agnes Hltkemeier Forschungszentrum Jülich GmbH

The construction of the Three Gorges Dam on the Yangtze River in China has a great influence on the ecosystems involved. In order to investigate these environmental effects in the Yangtze catchment area as well as downstream of the dam, Forschungszentrum Julich has organized a research network for the Chinese and Germaa partners. In the research fields of （1） interaction water/ sediment/contaminants, （2） vegetation/biodiversity, （3） changing land use/erosion/mass movements, and （4） atmosphere, the partners have accumulated a great deal of expertise in handling major issues and also in developing models and recommendations for action. The following provides an overview of the research network and the research tasks. On the German side, five projects in research field （3） have been in operation since 2008. The results are reported in contributions by Ehret et al., Jaehnig and Cai, Schonbrodt et al., and Seeber et al.. Another five projects in research field （1） have started by September 2010. The research tasks undertaken in these five projects are presented below.

关键词： Three Gorges Dam Yangtze River environmental research ecosystem.

Breast cancer liver metastasis:time to resection and criteria

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Hepatobiliary Surgery and Nutrition 2022年第5期11卷 749-751页

作者： Francesco Giovinazzo Angela Bucaro Salvatore agnes General Surgery and Liver Transplantation Unit Fondazione Policlinico Universitario Agostino GemelliRomeItaly

A manuscript recently published by Grazi pools outcomes from data on patients undergoing surgical resection for breast cancer liver metastases(BCLMs).In the manuscript,Grazi shows no definitive proof of liver resections(LR)effectiveness for ***,the author suggests surgery may be possible in selected patients(1-3).Several retrospective case series have been published evaluating patients’survival following resection for BCLM,reporting results for 5-year overall and disease-free *** tries to make recommendations based on the data that show which patients have a good prognosis following liver ***,the conclusion that surgical treatment is an option with a survival advantage for selected patients is not evident in the current literature as the criteria for surgery are not well established.

关键词： resection surgery cancer