检索结果-南通市图书馆

Paediatric-appropriate facilities in emergencydepartments of community hospitals in Ontario：A cross-sectional study

World Journal of Emergency Medicine 2017年第4期8卷 264-268页

作者： muhammad Akhter Hamid Sohaib Siddiqui Jabeen Fayyaz Ayesha Chandna Aliya Ariz Joe Butchey Elancheliyan Ambalavanar Niraj Mistry aftab muhammad azad Junaid A. Bhatti Dennis Scolnik Scarborough and Rouge Hospital Toronto Canada University of Toronto Department of Paediatrics Toronto Canada Sickkids Hospital Toronto Canada Saskatchewan Cancer Agency Regina Canada Hamilton Health Sciences Centre Hamilton Canada Hamad Medical Corporation Doha Qatar Sunnybrook Research Institute Toronto Canada

BACKGROUND: We assessed whether the paediatric-appropriate facilities were available at Emergency Departments(ED) in community hospitals in a Canadian ***: We conducted a cross-sectional survey of EDs in community hospitals in Ontario, Canada that had inpatient paediatric facilities and a neonatal intensive care unit. Key informants were ED chiefs, clinical educators, or managers. The survey included questions about paediatric facilities related to environment, triage, training, and staff in ***: Of 52 hospitals, 69%(n=36) responded to our survey. Of them, 14% EDs(n=5) had some separated spaces available for paediatric patients. About 53%(n=19) of EDs lacked children activities, e.g., toys. Only 11%(n=4) EDs were using paediatric triage scales and 42%(n=15) had a designated paediatric resuscitation bay. Only half of the ED(n=18) required from their staff to update paediatric life support training. Only 31%(n=11) had a designated liaison paediatrician for the ED. Paediatric social worker was present in only 8%(n=3) of EDs in community ***: Most of the Ontario community hospital EDs included in this survey had inadequate facilities for paediatric patients such as specific waiting and treatment areas.

关键词： Child-friendly Environment, Survey Triage Waiting area

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Repurposing of FDA-Approved drugs to predict new inhibitors against key regulatory genes in Mycobacterium tuberculosis

引用

BIOCELL 2021年第6期45卷 1569-1583页

作者： XINJUN YANG aftab ALAM NAIYAR IQBAL KHALID RAZA Department of Pediatrics 3201 HospitalHanzhongChina Centre for Interdisciplinary Research in Basic Sciences Jamia Millia IslamiaNew DelhiIndia Department of Computer Science and Information Technology Maulana Azad National Urdu UniversityHyderabadIndia Department of Computer Science Jamia Millia IslamiaNew DelhiIndia

Tuberculosis(TB)disease has become one of the major public health concerns globally,especially in developing *** research studies have already been carried out for TB,but we are still struggling for a complete and quick cure for *** progress of Mycobacterium tuberculosis(MTB)strains resistant to existing drugs makes its cure and control very ***,it is the need of the hour to search for newer and effective drugs that can inhibit an increasing number of putative drug *** applied the drug repurposing concept to identify promising FDAapproved drugs against five key-regulatory genes(FurB,IdeR,KstR,MosR,and RegX3)of the *** FDA drugs were virtually screened using a structure-based approach by GOLD versions 5.2,and subjected to rigid docking followed by an induced-fit docking algorithm to enhance the accuracy and prioritize drugs for *** found 11 candidate drugs(including ZINC03871613,ZINC03871614,ZINC03871615 as top scorer candidate drugs)that were frequently present within the top 20 GoldScore ranks and showed promising ***,molecular dynamics simulation was performed to monitor the effect of the top scorer drugs on the structural stability of all the five targets,indicating that inhibitors preferentially bind to the active site of the *** work suggests that these known FDA-approved drugs open new application domains in the form of anti-tuberculosis agents.

关键词： Virtual screening Molecular docking MD simulation PPI network

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：