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Asian Pacific Journal of Tropical Biomedicine 2015年第5期5卷 382-386页

作者： afrah eltayeb mohammed Department of Biology Faculty of Science Princess Nourah bint Abdulrahman University

Objective: To investigate the environmental-friendly extracellular biosynthetic technique for the production of the silver nanoparticles(AgN Ps) by using leaf extract of Eucalyptus camaldulensis(E. camaldulensis). Methods: The NP were characterized by colour changes and the UV-visible spectroscopy. The cytotoxic effects of prepared AgN Ps was detected against four types of pathogenic bacteria, including two Gram-negative bacteria(Pseudomonas aeruginosa and Escherichia coli) and two Gram-positive bacteria(Staphylococcus aureus and Bacillus subtilis) by using agar well diffusion method. Results: A peak absorption value between 400-450 nm for the extract and the colour change to dark brown were corresponding to the plasmon absorbance of AgN Ps. On the other hand, aqueous extract of E. camaldulensis leaves could be effective against tested microorganisms which showed inhibition zones of 9.0-14.0 mm. Furthermore, biologically synthesized AgN Ps had higher ability to suppress the growth of the tested microorganisms(12.0-19.0 mm). Conclusions: Our findings indicated that extracellular synthesis of Ag NPs mediated by E. camaldulensis leaf extract had an efficient bactericidal activity against the bacterial species tested. The exact mechanism of the extracellular biosynthesis of metal NP was not well understood. Further studies are needed to highlight the biosynthesis process of AgN Ps and also to characterize the toxicity effect of these particles.

关键词： Eucalyptus camaldulensis Silver nanoparticles Antimicrobial activity Bacteria

Diagnosing Breast Cancer Accurately Based on Weighting of HeterogeneousClassification Sub-Models

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Computer Systems Science & Engineering 2022年第9期42卷 1257-1272页

作者： Majdy Mohamed eltayeb Eltahir Tarig mohammed Ahmed Department of Information Systems College of Science&Arts at MahayilKing Khalid UniversityMuhayel Aseer62529Kingdom of Saudi Arabia Department of Information Technology Faculty of Computing and Information TechnologyKing Abdul-Aziz UniversityJeddah21589Kingdom of Saudi Arabia Department of Computer Sciences Faculty of Mathematical Sciences and InformaticsUniversity of KhartoumKhartoum11115Sudan

In developed and developing countries, breast cancer is one of the leading forms of cancer affecting women alike. As a consequence of growing lifeexpectancy, increasing urbanization and embracing Western lifestyles, the highprevalence of this cancer is noted in the developed world. This paper aims todevelop a novel model that diagnoses Breast Cancer by using heterogeneous datasets. The model can work as a strong decision support system to help doctors tomake the right decision in diagnosing breast cancer patients. The proposed modelis based on three datasets to develop three sub-models. Each sub-model worksindependently. The final diagnosis decision is taken by the three sub-models independently. The power of the model comes from the diversity checks of patientsand this reduces the risk of wrong diagnosing. The model has been developedby conducting intensive experiments. Several classification algorithms were usedto select the best one in each sub-model. As the final results, the sub-modelaccuracies were 72%, 74% and 97%.

关键词： Breast cancer data mining classification

Optimal Load Balancing in Cloud Environment of Virtual Machines

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Computer Systems Science & Engineering 2022年第6期41卷 919-932页

作者： Fuad A.M.Al-Yarimi Sami Althahabi Majdy mohammed eltayeb Department of Computer Science King Khalid UniversityMuhayel AseerKingdom of Saudi Arabia Department of Information System King Khalid UniversityMuhayel AseerKingdom of Saudi Arabia

Cloud resource scheduling is gaining prominence with the increasingtrends of reliance on cloud infrastructure solutions. Numerous sets of cloudresource scheduling models were evident in the literature. Cloud resource scheduling refers to the distinct set of algorithms or programs the service providersengage to maintain the service level allocation for various resources over a virtualenvironment. The model proposed in this manuscript schedules resources of virtual machines under potential volatility aspects, which can be applied for anypriority metric chosen by the server administrators. Also, the model can be flexible for any time frame-based analysis of the load factor. The model discussed inthis manuscript relies on the Bollinger Bands tool for understanding the potentialvolatility aspects of a Virtual Machine. The experimental study of the model compared to the contemporary load balancing model called STLB (Starvation Threshold-based Load Balancing) refers to a simple and potential model that can bemore pragmatic for sustainable ways of load balancing.

关键词： Cloud computing service level agreements virtual machines load balancing scheduling

Mortality and rebleeding following variceal haemorrhage in liver cirrhosis and periportal fibrosis

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World Journal of Hepatology 2016年第31期8卷 1336-1342页

作者： Sara Elfadil Abbas mohammed Abdelmunem eltayeb Abdo Hatim Mohamed Yousif Mudawi Department of Internal Medicine Faculty of MedicineUniversity of Khartoum National Centre for Gastrointestinal and Liver Disease Ibn Sina specialized Hospital

AIMTo investigate mortality and rebleeding rate and identify associated risk factors at 6 wk and 5 d following acute variceal haemorrhage in patients with liver cirrhosis and schistosomal periportal fibrosis. METHODSThis is a prospective study conducted during the period from March to December 2014. Patients with portal hypertension presenting with acute variceal haemorrhage secondary to either liver cirrhosis (group A) or schistosomal periportal fibroses (group B) presenting within 24 h of the onset of the bleeding were enrolled in the study and followed for a period of 6 wk. Analysis of data was done by Microsoft Excel and comparison between groups was done by Statistical Package of Social Sciences version 20 to calculate means and find the levels of statistical differences and define the mortality rates, the P value of RESULTSA total of 94 patients were enrolled in the study. Thirty-two patients (34%) had liver cirrhosis (group A) and 62 (66%) patients had periportal fibrosis (group B). Mortality: The 6-wk and 5-d mortality were 53% and 16% respectively in group A compared to 10% and 0% in group B (P value P value P value P value P value P value P value CONCLUSIONThe 6-wk and 5-d mortality and rebleeding rate were significantly higher in patients with liver cirrhosis compared to patients with schistosomal periportal fibrosis.

关键词： Variceal haemorrhage Periportal fibrosis Liver cirrhosis Mortality Rebleeding

Carbamazepine solubility enhancement in tandem with swellable polymer osmotic pump tablet: A promising approach for extended delivery of poorly water-soluble drugs

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Asian Journal of Pharmaceutical Sciences 2014年第3期9卷 146-154页

作者： Hadjira Rabti Jumah Masoud mohammed Salmani eltayeb Sulimen Elamin Narimane Lammari Jie Zhang Qineng Ping Department of Pharmaceutics School of PharmacyChina Pharmaceutical University24 TongjiaxiangNanjing 210009China Department of Pharmaceutics College of PharmacyAl-Mustansiriya UniversityAl-Qadisiya DistrictBaghdadIraq Department of Pharmaceutics Faculty of PharmacyOmdurman Islamic UniversityKhartoum 00249Sudan

Elementary osmotic pump(EOP)is a unique extended release(ER)drug delivery system based on the principle of *** has the ability to minimize the amount of the drug,accumulation and fluctuation in drug level during chronic ***(CBZ),a poorly water-soluble antiepileptic drug,has serious side effects on overdoses and chronic *** aim of the present study was to design a new EOP tablet of CBZ containing a solubility enhancers and swellable polymer to reduce its side effects and enhance the patient ***,a combination of solubilizing carriers was selected to improve the dissolution of the slightly soluble ***,designing the new EOP tablet and investigating the effect of different variables of core and coat formulations on drug release behavior by single parameter optimization and by Taguchi orthogonal design with analysis of variance(ANOVA),*** results showed that CBZ solubility was successfully enhanced by a minimum amount of combined polyvinyl pyrrolidone(PVP K30)and sodium lauryl sulfate(SLS).The plasticizer amount and molecular weight(MW)together with the osmotic agent amount directly affect the release rate whereas the swellable polymer amount and viscosity together with the semi-permeable membrane(SPM)thickness inversely influence the release *** addition,the tendency of following zero order kinetics was mainly affected by the coat components rather than those of the ***,orifice size does not have any significant effect on the release behavior within the range of 0.1 mm to 0.8 *** this study we report the successful formulation of CBZ-EOP tablets,which were similar to the marketed product Tegretol CR 200 and able to satisfy the USP criterion limits and to deliver about 80%of CBZ at a rate of approximately zero order for up to 12 h.

关键词： Elementary osmotic pump Carbamazepine Solubility enhancement Taguchi orthogonal design Zero order

Peripheral Hematological Parameters in Sudanese Women with Polycystic Ovary Syndrome

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Case Reports in Clinical Medicine 2022年第7期11卷 253-260页

作者： Shaza mohammed Enaam T. Elhaj Mohamed A. Ahmed Reem eltayeb Ishag Adam Faculty of Medicine and Health Sciences Al-Neelain University Khartoum Sudan College of Applied Medical Sciences Shaqra University Shaqra Kingdom of Saudi Arabia Department of Obstetrics and Gynecology Unaizah College of Medicine and Medical Sciences Qassim University Unaizah Kingdom of Saudi Arabia Faculty of Medicine University of Khartoum Khartoum Sudan

The aim of this study is to assess the association between polycystic ovarian syndrome (PCOS) and hematological parameters [hemoglobin, red cell parameters, white blood cells (WBCs), platelets volume (MPV)]. This is a matched case-control study (60 women in each arm of the study) which was conducted in Saad Abualila infertility center Hospital in Khartoum, Sudan. Infertile women with PCOS were the cases and healthy non pregnant women were the controls. The gynecological characteristics were gathered through questionnaire and blood samples were analyzed for different blood parameters by automated hematology analyzer. While the two groups were matched in their age;body mass index was significantly higher in women with PCOs compared to the normal control. The investigated different hematological parameters (hemoglobin, RBCs, RDW, WBCs, platelets and MPV) showed no statistical difference between the women with PCOS and the controls.

关键词： Hemoglobin Platelets Volume Polycystic Ovarian Syndrome Red Blood Cells White Blood Cells

Determinations of Amino Acids and Fatty Acids Levels in Date Palm Kernel Flour in Sudan

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Journal of Agricultural Science and Technology(A) 2020年第5期10卷 283-289页

作者： Rehab Salih Mahmoud Abdalla mohammed Ahmed Hassan eltayeb Ammar mohammed Elamin Hassan Abdelrahim Mohamed El Hussein Sudanese Nuclear and Radiological Regulatory Authority Ministry of Higher Education and Scientific ResearchKhartoum 11111Sudan Sudan Academy of Sciences Ministry of Higher Education and Scientific ResearchKhartoum 11111Sudan Sudan Atomic Energy Commission Ministry of Higher Education and Scientific ResearchKhartoum 11111Sudan Central Laboratory Ministry of Higher Education and Scientific ResearchKhartoum 11111Sudan

The aim of this study was the determination of various levels in date palm kernel(DPK)flour for enhancing production performance of animals natural feed in Sudan,in addition to protecting the environment from *** material used is flour of date seeds from the following date varieties:Berkawi,Gandilla,Tamouda,Klmah,Mashreq Wad Khatib,Mashreq Wad *** research was conducted at the following institutions:Geological Research Authority of Sudan,preparation of the DPK;Institute Penyelidikan Produk Halal of University Putra Malaysia,determination of amino acids using high performance liquid chromatography mass spectroscopy mass spectroscopy(HPLC MSMS)fluorescence;University of Medical Sciences and Technology-Sudan,determination of fatty acids using gas chromatography-mass spectrometry(GC-MS).Seeds were collected from various areas of Sudan and from *** seeds were mixed together and they weigh 8 *** preparation includes five steps,namely(1)washing,(2)soaking,(3)flushing,(4)drying,(5)*** flour was then used to determine its contents of amino acids by high performance liquid chromatography-fluorescence detector(HPLC-FLD)and fatty acids by *** of the following amino acids were determined in the sample(percentages in w/w are indicated between parenthesis):hydroxyprofine(0.224),aspartic acid(7.029),serine(6.350),glutamic acid(1.745),glycine(3.183),histicline(0.705),arginine(7.262),threonine(ND),alanine(15.558),proline(4.302),cysteine(34.326),tyrosine(2.070),voline(0.402),methionine(2.989),lysine(4.723),isoleucine(2.203),leucine(4.485),phenylalanine(2.442)while the determined fatty acids are:lauric acid(11.765),tetradecanoic acid(14.214),methyl palmitoleate(16.235),palmitic acid(16.431),cis-10-Heptadecenoic acid,methyl ester(17.253),margaric acid(17.464),linoleic acid(18.183),oleic acid(18.236),stearic acid(18.449),methyl ester(20.106)and arachidic acid(20.308).The seeds of the dates are found to be rich in amino acids as well a

关键词： DPK solid waste nutritional value amino acids fatty acids

Five-year retrospective hospital-based study on epidemiological data regarding human leishmaniasis in West Kordofan state,Sudan

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World Journal of Clinical Infectious Diseases 2022年第2期12卷 61-68页

作者： Abdullah Abdulslam Abdullah Musa Ahmed Ahmed Gadeed Adam eltayeb Safa Ahmed Suad Hamad mohammed Hussein Department of Biomedical Sciences Faculty of Veterinary SciencesUniversity of GadarifGadarif 208Sudan Department of Reproductive Health Sciences Pan African University Life and Earth Sciences InstituteUniversity of IbadanIbadan 119Oyo StateNigeria Department of Veterinary Surgery and Anaesthesia Faculty of Veterinary MedicineALsalam UniversityAl-fula 120West Kordofan StateSudan Environmental Studies and Research Center Al-Salam UniversityAl-fula 120West Kordofan StateSudan Al-Sadaga Hospital Al-fula 124West Kordofan StateSudan Department of Zoonotic Disease and Disease Control Ministry of Animal ResourcesAl-Hamadi 215South Kordofan StateSudan Department of Statistics and Health Information Ministry of HealthAlfula 127West Kordofan StateSudan

BACKGROUND Leishmaniasis is a neglected zoonotic disease,endemic in *** this disease is very important to inform the health care policymakers and the governments to apply proper health and economic *** To find out the frequency and distribution of human leishmaniasis based on sex and age for 5 years in the West Kordofan state,*** A 5-year retrospective study from 2016 through 2020 was carried out using local hospital records of leishmaniasis *** positive results were recorded after performing at least one of the following leishmaniasis standard tests:direct agglutination test,enzyme-linked immunosorbent assay and leishmania skin *** sex and age of each patient were *** collected data were analyzed using STATA package version *** A total of 162443 patient records from 2016 to 2020 were *** these,4.39%were found to be positive for *** disease has been more common in males(65.3%)than in females(34.7%).The highest reported prevalence(6.58%)was in patients 15-44 years,and the lowest prevalence(1.95%)was among patients≥65 *** The results of the current study indicate that leishmaniasis is endemic in the study area even though the numbers of patients in the 5 consecutive years were *** addition,the disease was common in males and *** interpretation of these findings should take into consideration the absence of information about some important confounding factors.

关键词： Epidemiology Human Leishmaniasis West Kordofan Sudan Endemicity

Oral candidiasis and potential risk factors among disabled and nondisabled in Al-Baha region, Saudi Arabia

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World Journal of Clinical Cases 2024年第27期12卷 6077-6086页

作者： Abdullah Ali H Alzahrani Nagesh Bhat Pankaj Kukreja eltayeb mohammed Alhassan Abdallah Ibrahim A Mudawi Faisal A Alzahrani Mohammad A Albanghali Department of Dental Health Faculty of Applied Medical SciencesAl-Baha UniversityAl Bahah 65731Saudi Arabia Department of Preventive Dental Sciences School of DentistryAlBaha UniversityAl Bahah 65731Saudi Arabia Department of Biomedical Dental Sciences School of DentistryAlBaha UniversityAl Bahah 65731Saudi Arabia Department of Medical Services General Administration Public SecurityThe Saudi Ministry of InteriorRiyadh 11235Saudi Arabia Department of Public Health Faculty of Applied Medical SciencesAl-Baha UniversityAl Bahah 65731Saudi Arabia

BACKGROUND Oral candidiasis(OC)is an oral health disease that could influence patients’oral health quality of *** To estimate prevalence of OC among disabled and non-disabled individuals and its potential risk factors in the Al-Baha region,Saudi *** An observational cross-sectional study was carried out among 148 disabled and non-disabled *** technique of concentrated oral rinse employing the Sabouraud Dextrose Agar medium accompanied with 0.05%chloramphenicol was conducted to assess and isolate *** examination using the World Health Organization guidelines was conducted to examine participants’oral hea-lth status.A pre-designed questionnaire was also used to evaluate sociodemo-graphic,medical history,and oral hygiene habits of the studied *** Out of 148 participants(n=57,38%)had colonized *** of the studied population had visible Candida ***,Candida was found in the oral rinses without the subject presenting any lesions or issues caused by Candida(asymptomatic colonization).The most common prevalent OC among participants were Candida albicans,Candida glabrata,Candida dubliniensis,Candida krusei,Candida tropicalis,and Candida parapsilosis(n=35,61%;n=8,14%;n=6,10%;n=5,9%;n=2,4%;and n=1,2%)***,smoking,poor plaque,and gingival status were key potential risk factors that significantly associated with candida’s density and presence(P=0.001,P=0.001,P=0.01,and P=0.01)*** status had no statistically significant effect on presence and density of *** The prevalence of OC is almost third of the studied population;thus,may provoke a need to develop preventive strategies to reduce the OC rate and establish solid treatment plans.

关键词： Oral health Candida Oral candidiasis Dental public health Disabled Disability Risk factors Epidemiology

Management and Outcome of Hyperemesis Gravidarum at Tertiary Obstetric Facility, Khartoum-Sudan

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Open Journal of Obstetrics and Gynecology 2016年第11期6卷 630-636页

作者： Atif B. Fazari Hasouna Z. S. Ahmed Rasha eltayeb mohammed H. Ali Khalifa Elmusharaf Reproductive and Child Health Research Unit University of Medical Sciences & Technology Khartoum Sudan Omdurman Maternity Hospital Ministry of Health Khartoum Sudan Latifa Hospital Dubai Health Authority Dubai UAE Police Hospital Red Sea State Port Sudan Sudan Academy Charity Teaching Hospital State Ministry of Health Khartoum Sudan Royal Preston Hospital Lancashire UK Graduate Entry Medical School University of Limerick Limerick Ireland

Introduction: Hyperemesis gravidarum (HG) is vomiting and/or nausea in pregnancy causes dehydration, electrolytes imbalance, weight loss and further serious organs dysfunction. Methods: This was a descriptive, prospective, cross-sectional hospital based total coverage analytic study, which was conducted from November 2013 to May 2014 at Omdurman New Hospital (ONH) for Obstetrics & Gynecology, Khartoum-Sudan. Results: HG prevalence is 13% of complicated pregnancy of ONH admission. Acetonurea is reported in all cases with significant association between acetonurea and smoking (P value = 0.005). A significant association between Hemoglobulin level and the readmission the (P value = 0.01) was reported. One maternal death is reported from severe hypoglycemia and liver impairment. Conclusion: Hyperemesis gravidarum has serious maternal morbidity with social negative impacts and significant financial burden on the health services.

关键词： Hyperemesis Gravidarum Acetonurea Maternal Morbidity