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Comprehensive analysis of glacier recession(2000-2020)in the Nun-Kun Group of Glaciers,Northwestern Himalaya

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Journal of Mountain Science 2024年第3期21卷 768-785页

作者： Shakil ahmad ROMSHOO Ummer AMEEN Mustafa Hameed BHAT Tariq ABDULLAH Department of Geoinformatics University of KashmirSrinagarKashmir 190006India Islamic University of Science and Technology AwantiporaKashmir 192122India Centre of Excellence for Glacier Studies in the Western Himalaya University of KashmirSrinagarKashmir 190006India

Himalayan glaciers are shrinking rapidly,especially after *** shrinkage,however,shows a differential pattern in space and time,emphasizing the need to monitor and assess glacier changes at a larger *** this study,changes of 48 glaciers situated around the twin peaks of the Nun and Kun mountains in the northwestern Himalaya,hereafter referred to as Nun-Kun Group of Glaciers(NKGG),were investigated using Landsat satellite data during *** in glacier area,snout position,Equilibrium Line Altitude(ELA),surface thickness and glacier velocity were assessed using remote sensing data supplemented by field *** study revealed that the NKGG glaciers have experienced a recession of 4.5%±3.4%and their snouts have retreated at the rate of 6.4±1.6 m·a^(-1).Additionally,there was a 41%increase observed in the debris cover area during the observation *** the geodetic approach,an average glacier elevation change of-1.4±0.4 m·a^(-1)was observed between 2000 and *** observed mass loss of the NKGG has resulted in the deceleration of glacier velocity from 27.0±3.7 m·a^(-1)in 2000 to 21.2±2.2 m·a^(-1)in *** ELA has shifted upwards by 83.0±22 m during the *** morphological and topographic factors showed a strong influence on glacier ***,a higher recession of 12.9%±3.2%was observed in small glaciers,compared to 2.7%±3.1%in larger *** debris-covered glaciers showed lower shrinkage(2.8%±1.1%)compared to the clean glaciers(9.3%±5%).The glacier depletion recorded in the NKGG during the last two decades,if continued,would severely diminish glacial volume and capacity to store water,thus jeopardizing the sustainability of water resources in the basin.

关键词： Nun-Kun range Glacier recession Glacier snout Remote Sensing Himalaya Glacier velocity

Recent advances in the diagnosis of drug-induced liver injury

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World Journal of Hepatology 2024年第2期16卷 186-192页

作者： Taqwa Ahmed Jawad ahmad Department of Medicine Icahn School of Medicine at Mount SinaiNew YorkNY 10029United States Department of Recanati-Miller Transplantation Institute Icahn School of Medicine at Mount SinaiNew YorkNY 10029United States

Drug-induced liver injury(DILI)is a major problem in the United States,commonly leading to hospital *** DILI is difficult as it is a diagnosis of exclusion requiring a temporal relationship between drug exposure and liver injury and a thorough work up for other *** addition,DILI has a very variable clinical and histologic presentation that can mimic many different etiologies of liver *** scoring systems can assess the probability that a drug caused the liver injury but liver biopsy findings are not part of the criteria used in these *** review will address some of the recent updates to the scoring systems and the role of liver biopsy in the diagnosis of DILI.

关键词： Drug induced liver injury Liver biopsy Diagnosis RUCAM RECAM

A Review of Privacy and Security of Edge Computing in Smart Healthcare Systems: Issues, Challenges, and Research Directions

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Tsinghua Science and Technology 2024年第4期29卷 1152-1180页

作者： ahmad Alzu’bi Ala’a Alomar Shahed Alkhaza’leh Abdelrahman Abuarqoub Mohammad Hammoudeh Department of Computer Science Jordan University of Science and TechnologyIrbid 22110Jordan Cardiff School of Technologies Cardiff Metropolitan UniversityCardiff CF52YBUK Department of Information and Computer Science King Fahd University of Petroleum and MineralsDhahran 31261Kingdom of Saudi Arabia

The healthcare industry is rapidly adapting to new computing environments and technologies. With academics increasingly committed to developing and enhancing healthcare solutions that combine the Internet of Things (IoT) and edge computing, there is a greater need than ever to adequately monitor the data being acquired, shared, processed, and stored. The growth of cloud, IoT, and edge computing models presents severe data privacy concerns, especially in the healthcare sector. However, rigorous research to develop appropriate data privacy solutions in the healthcare sector is still lacking. This paper discusses the current state of privacy-preservation solutions in IoT and edge healthcare applications. It identifies the common strategies often used to include privacy by the intelligent edges and technologies in healthcare systems. Furthermore, the study addresses the technical complexity, efficacy, and sustainability limits of these methods. The study also highlights the privacy issues and current research directions that have driven the IoT and edge healthcare solutions, with which more insightful future applications are encouraged.

关键词： edge computing fog computing data privacy healthcare systems intelligent edges

Volume-complementary bipolar layered oxide enables stable symmetric sodium-ion batteries

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Nano Research 2024年第5期17卷 4125-4133页

作者： Bo Peng Feng Wang Nazir ahmad Lai Yu Shenghua Chen Genqiang Zhang School of Materials Science and Engineering Key Laboratory of Efficient Conversion and Solid-state Storage of Hydrogen and Electricity of Anhui ProvinceAnhui University of TechnologyMa’anshan 243002China Hefei National Research Center for Physical Sciences at the Microscale Chinese Academy of Sciences(CAS)Key Laboratory of Materials for Energy ConversionDepartment of Materials Science and EngineeringUniversity of Science and Technology of ChinaHefei 230026China National Innovation Platform(Center)for Industry-Education Integration of Energy Storage Technology School of Chemical Engineering and TechnologyXi’an Jiaotong UniversityXi’an 710049China

The commercialization of sodium-ion batteries is based on developing low-cost,highly stable,and safe cathode and anode ***,the promising hard carbon anode and layered oxide cathode suffer from low sodium-embedded potential near 0.1 V and severe phase transitions,which cause safe problem and short lifespan,***,we design a low-strain bipolar P2-Na_(0.7)Ni_(0.25)Fe_(0.2)Ti_(0.55)O_(2) to solve the mentioned obstacles,whereas(Ni,Fe)and Ti provide charge compensation when it is used as cathode and anode,*** is revealed that the bipolar layered oxide undergoes solid-solution reaction when used as cathode or anode,and exhibits volume-complementary feature in a sodium-ion full-cell,as identified by in-situ X-ray ***,the safe symmetric sodium-ion full-cell exhibits excellent cyclic stability with 91.7%capacity retention after 200 *** work will provide a new horizon for designing safe and stable sodium-ion batteries.

关键词： sodium-ion batteries bipolar layered oxides solid-solution reaction volume complementation symmetric battery

Computational and bioinformatics tools for understanding disease mechanisms

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BIOCELL 2024年第6期48卷 935-944页

作者： MOHD ATHAR ANU MANHAS NISARG RANA ahmad IRFAN Physics Department University of CagliariCittadella UniversitariaMonserrato(CA)09042Italy Department of Chemistry School of Energy TechnologyPandit Deendayal Energy UniversityGandhinagar382426India Department of Chemistry College of ScienceKing Khalid UniversityAbha61413Saudi Arabia

Computational methods have signiﬁcantly transformed biomedical research,offering a comprehensive exploration of disease mechanisms and molecular protein *** article reviews a spectrum of computational tools and network analysis databases that play a crucial role in identifying potential interactions and signaling networks contributing to the onset of disease *** utilization of protein/gene interaction and genetic variation databases,coupled with pathway analysis can facilitate the identiﬁcation of potential drug *** bridging the gap between molecular-level information and disease understanding,this review contributes insights into the impactful utilization of computational methods,paving the way for targeted interventions and therapeutic advancements in biomedical research.

关键词： Interaction database Disease mechanisms Protein function Network analysis Bioinformatics Genetic variations Protein-protein interactions Signaling pathways

Radial solution of the Logarithmic Laplacian system

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Applied Mathematics(A Journal of Chinese Universities) 2024年第1期39卷 114-124页

作者： ZHANG Li-hong NIE Xiao-feng WANG Guo-tao Bashir ahmad School of Mathematics and Computer Science Shanxi Normal UniversityLinfen 041004China Nonlinear Analysis and Applied Mathematics(NAAM)Research Group Department of MathematicsFaculty of ScienceKing Abdulaziz UniversityJeddah 21589Saudi Arabia.

The paper generalizes the direct method of moving planes to the Logarithmic Laplacian ***,some key ingredients of the method are discussed,for example,Narrow region principle and Decay at ***,the radial symmetry of th... 详细信息

关键词： the Logarithmic Laplacian system radial symmetry the direct method of moving planes

Impact of index admission cholecystectomy vs interval cholecystectomy on readmission rate in acute cholangitis: National Readmission Database survey

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World Journal of Gastrointestinal Endoscopy 2024年第6期16卷 350-360页

作者： Abdullah Sohail Ahmed Shehadah Ammad Chaudhary Khadija Naseem Amna Iqbal ahmad khan Shailendra Singh Department of Internal Medicine University of Iowa Roy J and Lucille A Carver College of MedicineIowaIA 52242United States Department of Internal Medicine Rochester General HospitalRochesterNY 14621United States Department of Internal Medicine Henry Ford HospitalDetroitMI 48202United States Department of Internal Medicine Cleveland Clinic FoundationClevelandOH 44195-0001United States Department of Internal Medicine University of ToledoToledoOH 43606United States Department of Gastroenterology and Hepatology Case Western Reserve University HospitalClevelandOH 44106United States Division of Gastroenterology and Hepatology West Virginia University School of MedicineMorgantownWV 26505United States

BACKGROUND Elective cholecystectomy(CCY)is recommended for patients with gallstone-related acute cholangitis(AC)following endoscopic decompression to prevent recurrent biliary ***,the optimal timing and implications of CCY remain *** To examine the impact of same-admission CCY compared to interval CCY on patients with gallstone-related AC using the National Readmission Database(NRD).METHODS We queried the NRD to identify all gallstone-related AC hospitalizations in adult patients with and without the same admission CCY between 2016 and *** primary outcome was all-cause 30-d readmission rates,and secondary outcomes included in-hospital mortality,length of stay(LOS),and hospitalization *** Among the 124964 gallstone-related AC hospitalizations,only 14.67%underwent the same admission *** all-cause 30-d readmissions in the same admission CCY group were almost half that of the non-CCY group(5.56%vs 11.50%).Patients in the same admission CCY group had a longer mean LOS and higher hospitalization costs attrib-utable to *** the most common reason for readmission was sepsis in both groups,the second most common reason was AC in the interval CCY *** Our study suggests that patients with gallstone-related AC who do not undergo the same admission CCY have twice the risk of readmission compared to those who undergo CCY during the same *** readmis-sions can potentially be prevented by performing same-admission CCY in appropriate patients,which may reduce subsequent hospitalization costs secondary to readmissions.

关键词： Acute cholangitis Gallstone-related complications National Readmission Database 30-d readmission rates Resource utilization In-hospital mortality

Cancer cell cycle heterogeneity as a critical determinant of therapeutic resistance

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Genes & Diseases 2024年第1期11卷 189-204页

作者： Ebrahim H.Maleki ahmad Reza Bahrami Maryam M.Matin Department of Biology Faculty of ScienceFerdowsi University of Mashhad*** MashhadIran Jagiellonian Centre for Experimental Therapeutics(JCET) Jagiellonian University31-007 KrakowPoland Doctoral School of Exact and Natural Sciences Jagiellonian University30-348 KrakowPoland Industrial Biotechnology Research Group Institute of BiotechnologyFerdowsi University of Mashhad*** MashhadIran Novel Diagnostics and Therapeutics Research Group Institute of BiotechnologyFerdowsi University of Mashhad***MashhadIran Stem Cell and Regenerative Medicine Research Group Iranian Academic Center for EducationCulture and Research(ACECR)Khorasan Razavi Branch917751376 MashhadIran

Intra-tumor heterogeneity is now arguably one of the most-studied topics in tumor biology,as it represents a major obstacle to effective cancer *** tumor cells are highly diverse at genetic,epigenetic,and phenotypic levels,intra-tumor heterogeneity can be assumed as an important contributing factor to the nullification of chemotherapeutic effects,and recurrence of the *** on the role of heterogeneous subpopulations of cancer cells with varying cell-cycle dynamics and behavior during cancer progression and treatment;herein,we aim to establish a comprehensive definition for adaptation of neoplastic cells against *** discuss two parallel and yet distinct subpopulations of tumor cells that play pivotal roles in reducing the effects of chemotherapy:"resistant"and"tolerant"***,this review also highlights the impact of the quiescent phase of the cell cycle as a survival mechanism for cancer *** understanding the mechanisms under-lying the quiescence,it provides an insightful perspective on cancer stem cells(CsCs)and their dual and intertwined functions based on their cell cycle state in response to ***-over,CSCs,epithelial-mesenchymal transformed cells,circulating tumor cells(CTCs),and disseminated tumor cells(DTCs),which are mostly in a quiescent state of the cell cycle are proved to have multiple biological links and can be implicated in our viewpoint of cell cycle heterogeneity in ***,increasing our knowledge of cell cycle heterogeneity is a key to identifying new therapeutic solutions,and this emerging concept may provide us with new opportunities to prevent the dreadful cancer recurrence.

关键词： Cancer stem cells(CSCs) Carcinoma Cell cycle heterogeneity Quiescence Therapy resistance Therapy tolerance Tumor dormancy

Robust design of sliding mode control for airship trajectory tracking with uncertainty and disturbance estimation

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Journal of Systems Engineering and Electronics 2024年第1期35卷 242-258页

作者： WASIM Muhammad ALI Ahsan CHOUDHRY Mohammad ahmad SHAIKH Inam Ul Hasan SALEEM Faisal Department of Aeronautics and Astronautics Engineering Institute of Space TechnologyIslamabad 44000Pakistan Department of Electrical Engineering University of Engineering and TechnologyTaxila 47080Pakistan Department of Measurements and Control Systems Silesian University of TechnologyGliwice 44-101Poland The Joint Doctoral School Silesian University of TechnologyGliwice 44-100Poland

The robotic airship can provide a promising aerostatic platform for many potential *** applications require a precise autonomous trajectory tracking control for *** has a nonlinear and uncertain *** is prone to wind disturbances that offer a challenge for a trajectory tracking control *** paper addresses the airship trajectory tracking problem having time varying reference path.A lumped parameter estimation approach under model uncertainties and wind disturbances is opted against distributed *** uses extended Kalman filter(EKF)for uncertainty and disturbance *** estimated parameters are used by sliding mode controller(SMC)for ultimate control of airship trajectory *** comprehensive algorithm,EKF based SMC(ESMC),is used as a robust solution to track airship *** proposed estimator provides the estimates of wind disturbances as well as model uncertainty due to the mass matrix variations and aerodynamic model *** stability and convergence of the proposed method are investigated using the Lyapunov stability *** simulation results show that the proposed method efficiently tracks the desired *** method solves the stability,convergence,and chattering problem of SMC under model uncertainties and wind disturbances.

关键词： airship chattering extended Kalman filter(EKF) model uncertainties estimation sliding mode controller(SMC)