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Clinical characteristics and surgical treatment of schwannomas of the esophagus and stomach: A case series and systematic review

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World Journal of Gastrointestinal Oncology 2019年第9期11卷 750-760页

作者： Jesús Morales-Maza Francisco Ulises Pastor-Sifuentes Germán E Sánchez-Morales Emilio Sanchez-Garcia Ramos Oscar Santes Uriel Clemente-Gutiérrez adriana simoneta pimienta-ibarra Heriberto Medina-Franco Department of Surgery Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán

BACKGROUND Gastrointestinal schwannomas are slow-growing benign mesenchymal neoplasms that originate from Schwann cells of the nerve sheath of Auerbach′s plexus or less frequently from Meissner′s *** main differential diagnosis of gastric schwannomas are the gastrointestinal stromal tumors(GISTs),which are classified by their *** treatment of choice for gastric schwannomas is surgery where laparoscopy plays an important *** resection,subtotal or total gastrectomy can be *** its counterpart,esophageal schwannomas are benign tumors of the esophagus that are very uncommon since they comprise less than 2%of all esophageal *** main differential diagnosis is the leiomyoma which corresponds to the most common benign esophageal tumor,followed by *** treatment consists on tumoral enucleation or *** To review the available literature about gastrointestinal schwannomas;especially lesions from de stomach and esophagus,including diagnosis,treatment,and follow up,as well as,reporting our institutional *** A systematic review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyzes *** following databases were used for reviewing process:Pub Med,Ovid,MEDLINE,and *** English language manuscripts were *** gastrointestinal schwannomas specifically located in the esophagus and stomach were *** that did not report long-term follow-up were *** Gastric localization showed a higher prevalence in both,the literature review and our institution:94.95%(n=317)and 83%(n=5)*** a follow-up with disease-free survival greater than 36 mo in most cases:62.01%(n=80)vs66.66%(n=4).In both groups,the median size was>4.1 *** treatment is curative in most cases CONCLUSION Schwannoma must be taken into account in the differential diagnosis of gastrointestinal mesenchymal *** has a good prognosis,and most are benig

关键词： Schwannoma Esophagus Stomach Surgery Systematic review

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