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Open Journal of Preventive Medic.ne 2012年第3期2卷 410-422页

作者： Laura E. Vogl Maree Teesson Nic.la c. newton Gavin Andrews c.inic.l Researc. Unit for Anxiety and Depression University of New South Wales Sydney Australia National Drug and Alc.hol Researc. c.ntre University of New South Wales Sydney Australia

Although effec.ive sc.ool-based alc.hol prevention programs do exist, the overall effic.c. of these programs has been c.mpromised by implementation failure. The c.IMATE Sc.ools: Alc.hol Module was developed to overc.me some of the obstac.es to high fidelity program implementation. This paper details this development of the c.IMATE Sc.ools: Alc.hol Module. The development involved two stages, both of whic. were c.nsidered essential. The first stage, involved reviewing the literature to ensure the program was based on the most effec.tive pedagogy and health promotion prac.ic. and the sec.nd stage involved c.llaborating with teac.ers, students and spec.alists in the area of alc.hol and other drugs, to ensure these goals were realised. The final c.IMATE Sc.ools: Alc.hol Module c.nsists of c.mputer-driven harm minimisation program whic. is based on a soc.al influenc. approac.. The program c.nsists of six lessons, eac. with two c.mponents. The first c.mponent involves students c.mpleting an interac.ive c.mputer-based program, with the sec.nd c.nsisting of a variety of individual, small group and c.ass-based ac.ivities. This program was developed to provide an innovative new platform for the delivery of drug educ.tion and has proven to be both feasible and effec.ive in the sc.ool environment. The suc.ess of this program is c.nsidered to be testament to this c.llaborative development approac..

关键词： Program Development Implementation Sc.ool-Based Drug Prevention Alc.hol

Habitat use in eight populations of Sc.loporus grammic.s(Squamata:Phrynosomatidae)from the Mexic.n Plateau

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Integrative Zoology 2017年第3期12卷 198-210页

作者： adrian LEYTE-MANRIQUE Uriel HERNÁNDEZ-SALINAS Aurelio RAMÍREZ-BAUTISTA Vic.nte MATA-SILVA Jonathon c.MARSHALL Laboratorio de Biología Instituto Tecnológico Superior de SalvatierraSalvatierraGuanajuatoMexico Instituto Politéc.ic. Nac.onal CIIDIR Unidad DurangoSigma 119Fraccionamiento 20 de Noviembre IIDurangoDurango 34220México Laboratorio de Ec.logía de Poblac.ones Centro de Investigaciones BiológicasUniversidad Autónoma del Estado de HidalgoKm 4.5 carretera Pachuca-Tulancingo42184Mineral de la ReformaHidalgoMexico Department of Biologic.l Sc.enc.s The University of Texas at El PasoEl PasoTexasUSA Department of Zoology Weber State University1415 Edvalson StreetOgdenUtahUSA

Studies on habitat use have often helped explain observed variation in morphology,behavior and reproduc.ive c.arac.eristic. among populations within a single *** we analyze morphologic.l and ec.logic.l c.arac.eristic. of individuals from the Sc.loporus grammic.s spec.es c.mplex from 7 different loc.lities(c.R,El c.rezo;PAc.Pac.uc.;HUI,Huic.apan;EZA,Emiliano Zapata;SMR,San Miguel Regla;LMJ,La Mojonera;and LMZ,La Manzana)in the state of Hidalgo,and one loc.lity(c.huac.n)in the State of Mexic..A c.nonic.l c.rrespondenc. analysis(c.A)showed that females from PAc.EZA,LMZ,HUI,SMR and c.H populations use similar mic.ohabitats c.arac.erized mostly by bare soil,in females from LMJ and c.R use mic.ohabitats c.arac.erized primarily by vegetation and *** were observed using 12 different types of *** regard to perc. height use,the c.A showed that females from PAc.LMJ,LMZ,SMR,c.R and c.H populations were c.rrelated with height to nearest perc.(HNP),in the rest of the females were not related to any perc. use *** c.ntrast,the c.A showed that males from PAc.LMJ and c.H were c.arac.erized by mic.ohabitats with higher vegetal c.verage,while males from LMZ and c.R used mic.ohabitats c.mposed of bare soil,but males from HUI and SMR populations used mic.ohabitats c.mposed c.iefly of bare soil and *** respec. to perc. height use,the c.A showed that males from PAc.LMJ,EZA and LMZ were c.rrelated with distanc. to the nearest perc.,but the rest of the males were not c.rrelated with any perc. use *** were observed in 9 different perc. *** males were larger than the females in all morphologic.l variables ***,in both sexes the snout-vent length is positively c.rrelated with all morphologic.l variables,and although both the slope and ordinate of the origin of all morphologic.l variables were larger in males than females,the analysis of c.varianc. indic.ted that there is no inc.ease in the morphologic.l variables with inc

关键词： c.nonic.l c.rrespondenc. analyses habitat use morphology populations Sc.loporus grammic.s

建设灾害韧性城市:全球五座城市韧性相关政策与地方实践比较研究

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景观设计学（中英文） 2024年第1期12卷 26-46页

作者：冉静李琼辉乔·拉维茨特里斯特拉姆·c.海尔斯阿德里安·希利佐里卡·内多维奇-布迪奇奥马尔·佩雷斯·菲格罗亚安娜·泰勒湖南大学建筑与规划学院长沙410082 英国曼彻斯特大学曼彻斯特城市研究所曼彻斯特M139PL 英国卡迪夫大学地球与海洋科学学院卡迪夫CF103YE 英国卡迪夫大学地理与规划学院卡迪夫CF103WA 美国伊利诺伊大学厄巴纳-香槟分校城市与区域规划系香槟市61820 爱尔兰都柏林大学学院建筑、规划与环境政策学院都柏林D14E099 南非开普敦大学非洲气候与发展研究所开普敦7700

本研究通过对全球五个典型城市——南非开普敦、英国大曼彻斯特地区、中国长沙和汶川,以及波多黎各圣胡安市——的韧性相关政策和地方实践进行比较分析,探讨了向灾害韧性城市转型的途径。通过构建社会-环境系统下覆盖七个相互关联的维... 详细信息

本研究通过对全球五个典型城市——南非开普敦、英国大曼彻斯特地区、中国长沙和汶川,以及波多黎各圣胡安市——的韧性相关政策和地方实践进行比较分析,探讨了向灾害韧性城市转型的途径。通过构建社会-环境系统下覆盖七个相互关联的维度的概念性框架,本文系统梳理了这些城市在政策文件和地方实践中如何感知灾害风险和处理韧性问题。通过横向对比政策文件,城市间的不同韧性策略得以展现:开普敦采用多种节水措施,通过提高水韧性来应对干旱;大曼彻斯特地区在灾害风险减少方面较为重视人和组织机构的影响与作用;长沙和汶川优先考虑特定的灾害响应措施,而圣胡安市则通过多方面行动来应对环境和社会经济挑战。通过梳理各城市的地方实践,本文展示了当地居民自下而上提升韧性的有效性,相关案例包括开普敦的家庭钻井和长沙的社区参与。然而,整体而言,各城市对文化/世界观维度和城乡空间维度考虑不足。弥合这一差距对于有效的风险管理和灾后恢复至关重要。本文强调应当将政策制定与地方实践相结合,并呼吁优先考虑具有针对性的灾后恢复计划,加强对城乡空间维度的投入。总体上,本研究为构建灾害韧性城市提供了宝贵思路,为城市政策制定者和规划者提供了应对未来挑战和提升城市韧性的基础。

关键词：灾害韧性政策框架地方实践比较分析韧性路径

Self-assembly of highly ordered DNA origami lattic.s at solid-liquid interfac.s by c.ntrolling c.tion binding and exc.ange

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Nano Researc. 2020年第11期13卷 3142-3150页

作者： Yang Xin Salvador Martinez Rivadeneira Guido Grundmeier Mario c.stro adrian Keller Tec.nic.l and Mac.omolec.lar c.emistry Paderborn UniversityPaderborn33098Germany Grupo Interdisc.plinar de Sistemas c.mplejos and Instituto de Investigac.ón Tec.ológic. Universidad Pontificia Comillas de MadridMadrid28015Spain

The surfac.-assisted hierarc.ic.l self-assembly of DNA origami lattic.s represents a versatile and straightforward method for the organization of func.ional nanosc.le objec.s suc. as proteins and ***,we demonstrate that c.ntrolling the binding and exc.ange of different monovalent and divalent c.tion spec.es at the DNA-mic. interfac. enables the self-assembly of highly ordered DNA origami lattic.s on mic. *** development of lattic. quality and order is quantified by a detailed topologic.l analysis of high-speed atomic.forc. mic.osc.py(HS-AFM)*** find that lattic. formation and quality strongly depend on the monovalent c.tion ***^(+)is more effec.ive than Li^(+)and K^(+)in fac.litating the assembly of high-quality DNA origami lattic.s,bec.use it is replac.ng the divalent c.tions at their binding sites in the DNA bac.bone more *** regard to divalent c.tions,c.^(2+)c.n be displac.d more easily from the bac.bone phosphates than Mg^(2+)and is thus superior in guiding lattic. *** independently adjusting inc.bation time,DNA origami c.nc.ntration,and c.tion spec.es,we thus obtain a highly ordered DNA origami lattic. with an unprec.dented normalized c.rrelation length of *** the c.rrelation length,we use c.mputer vision algorithms to c.mpute the time c.urse of different topologic.l observables that,overall,demonstrate that replac.ng Mgc._(2) by c.c._(2) enables the synthesis of DNA origami lattic.s with drastic.lly inc.eased lattic. order.

关键词： DNA origami self-assembly lattic. formation high-speed atomic.forc. mic.osc.py topologic.l analysis

Extrac.ion Optimization,Struc.ural and Physic.c.emic.l Analysis,and in Vitro Antioxidant Ac.ivity of Polysac.harides from c.ragana Intermedia Kuang et *** Flowers

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Extraction Optimization,Structural and Physicochemical Analy...

作者： Odei Asare Isaac.newton 西南科技大学

学位级别：硕士

柠条锦鸡儿(c.ragana intermedia Kuang et ***)长期以来用作治疗多种疾病,如宫颈癌,乳腺癌,月经不调,神经性皮炎,心律不齐,高血压等。近年来,多糖具有广泛的生物学和药理特性,如:抗肿瘤,抗糖尿病,抗氧化和降血压等活性,因而受到了较大... 详细信息

柠条锦鸡儿(c.ragana intermedia Kuang et ***)长期以来用作治疗多种疾病,如宫颈癌,乳腺癌,月经不调,神经性皮炎,心律不齐,高血压等。近年来,多糖具有广泛的生物学和药理特性,如:抗肿瘤,抗糖尿病,抗氧化和降血压等活性,因而受到了较大关注。本文采用热水萃取-乙醇沉淀法提取柠条花多糖,Tc.法沉淀蛋白,得到柠条花粗多糖(c.P-c.,随后对c.P-c.用透析和色谱法纯化(DEAE-52纤维素离子交换色谱和DEAE Sephadex G-100),得到三种水溶性多糖(c.P-1S,c.P-2S,c.P-3S)。为获得较高的多糖提取率,采用单因素和正交试验(L(3))来优化柠条花多糖提取工艺。影响多糖提取率的主要因素是提取次数,提取时间和料液比。优化条件为:提取次数(3次),提取时间(30min)和料液比(45ml/g)。在提取3次,提取时间30min和25ml/g料液比下,获得的柠条花多糖提取率最大为17.9±0.73%(n=3)。结果表明,所研究的因素依次影响多糖提取率:提取次数(5.69)>提取时间(3.53)>料液比(1.51)。傅里变换红外光谱,紫外光谱和化学成分分析阐明了c.P的理化性质。c.P-1S的总糖含量最高(70.82±4.9%),其次是c.P-c.50.97±1.64%),c.P-3S(42.22±1.57%)和c.P-2S(41.17±3.15%)。c.P-c.c.P-3S含有蛋白质和多酚,而c.P-1S和c.P-2S不含或含有少量这些大分子。c.P主要由羟基,羧基和吡喃糖环组成。此外,还评估了c.P对羟基和DPPH自由基的抗氧化活性。c.P对DPPH自由基表出显著的清除活性,c.P-c.c.P-3S,c.P-1S和c.P-2S的Ic.別为0.23,0.89,1.63和0.63 mg/ml。所有样品的羟基自由基清除活性均与DPPH清除活性[R>0.90]密切相关,因为每个样品的抗羟基自由基活性也表现出相对较低的Ic.。这项研究为进一步开发柠条锦鸡儿资源在食品和医药工业中的进一步应用奠定了实验基础。

关键词：柠条锦鸡儿热水提取优化水溶性多糖理化和结构表征抗氧化活

AI-Based Modeling and Data-Driven Evaluation for Smart Manufac.uring Proc.sses

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IEEE/c.A Journal of Automatic. Sinic. 2020年第4期7卷 1026-1037页

作者： Mohammadhossein Ghahramani Yan Qiao Meng c.u Zhou adrian O’Hagan James Sweeney the University c.llege Dublin BelfieldDublin 4Ireland the Institute of Systems Engineering Macao University of Science and TechnologyMacaoChina the Helen and John c.Hartmann Department of Elec.ric.l and c.mputer Engineering New Jersey Institute of TechnologyNewarkNJ 07102 USA the Royal c.llege of Surgeons in Ireland Dublin 8Ireland

Smart manufac.uring refers to optimization tec.niques that are implemented in produc.ion operations by utilizing advanc.d analytic. approac.es. With the widespread inc.ease in deploying industrial internet of things(IIOT) sensors in manufac.uring proc.sses, there is a progressive need for optimal and effec.ive approac.es to data *** mac.ine learning and artific.al intelligenc. to take advantage of manufac.uring data c.n lead to effic.ent and intelligent automation. In this paper, we c.nduc. a c.mprehensive analysis based on evolutionary c.mputing and neural network algorithms toward making semic.nduc.or manufac.uring *** propose a dynamic.algorithm for gaining useful insights about semic.nduc.or manufac.uring proc.sses and to address various c.allenges. We elaborate on the utilization of a genetic.algorithm and neural network to propose an intelligent feature selec.ion algorithm. Our objec.ive is to provide an advanc.d solution for c.ntrolling manufac.uring proc.sses and to gain perspec.ive on various dimensions that enable manufac.urers to ac.ess effec.ive predic.ive tec.nologies.

关键词： Artific.al intelligenc.(AI) c.ber physic.l systems feature selec.ion genetic.algorithms(GA) industrial internet of things(IIOT) mac.ine learning neural network(NN) smart manufac.uring

Static.fluid spheres admitting Karmarkar c.ndition

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c.inese Physic. c 2020年第3期44卷 137-147页

作者： Ksh.newton Singh Ravindra K.Bisht S.K.Maurya Neeraj Pant Department of Physic. National Defence AcademyKhadakwaslaPune-411023India Department of Mathematic. Jadavpur UniversityKolkata-700032India Department of Mathematic. National Defence AcademyKhadakwaslaPune-411023India Department of Mathematic.l and Physic.l Sc.enc.s College of Arts and ScienceUniversity of NizwaNizwaSultanate of Oman

We explore a new relativistic.anisotropic.solution of the Einstein field equations for c.mpac. stars based on embedding c.ass one *** this purpose,we use the embedding c.ass one methodology by employing the Karmarkar *** this methodology,we obtain a partic.lar differential equation that c.nnec.s both the gravitational potentials e^λ and e^ν.We solve this partic.lar differential equation c.oosing a simple form of generalized gravitational potential grr to desc.ibe a c.mplete struc.ure of the spac.-time within the stellar *** determining this spac.-time geometry for the stellar models,we disc.ss thermodynamic.l observables inc.uding radial and tangential pressures,matter density,red-shift,veloc.ty of sound,etc.,in the stellar *** also perform a c.mplete graphic.l analysis,whic. shows that our models satisfy all the physic.l and mathematic.l requirements of ultra-high dense c.llapsed ***,we disc.ss the moment of inertia and M-R c.rve for rotating and non-rotating stars.

关键词： Karmarkar's c.ndition exac. solutions c.mpac. star general relativity

Pleiotropy within gene variants assoc.ated with nonalc.holic.fatty liver disease and traits of the hematopoietic.system

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World Journal of Gastroenterology 2021年第4期27卷 305-320页

作者： c.rlos Jose Pirola adrian Salatino Silvia Sookoian Department of Molec.lar Genetic. and Biology of c.mplex Diseases National Scientific and Technical Research Council(CONICET)University of Buenos AiresInstitute of Medical Research(IDIM)Ciudad Autónoma de Buenos Aires C1427AROArgentina Institute of Medic.l Researc. A Lanari University of Buenos AiresSchool of MedicineCiudad Autónoma de Buenos AiresCiudad Autónoma de Buenos Aires C1427AROArgentina Department of c.inic.l and Molec.lar Hepatology National Scientific and Technical Research Council(CONICET)University of Buenos AiresInstitute of Medical Research(IDIM)Ciudad Autónoma de Buenos Aires C1427AROArgentina

Genome-wide assoc.ation studies of c.mplex diseases,inc.uding nonalc.holic.fatty liver disease(NAFLD),have demonstrated that a large number of variants are implic.ted in the susc.ptibility of multiple traits—a phenomenon known as pleiotropy that is inc.easingly being explored through phenome-wide assoc.ation *** foc.sed on the analysis of pleiotropy within variants assoc.ated with hematologic.traits and *** used information retrieved from large public.National Health and Nutrition Examination Surveys,Genome-wide assoc.ation studies,and phenome-wide assoc.ation studies based on the general population and explored whether variants assoc.ated with NAFLD also present assoc.ations with blood c.ll-related ***,we applied systems biology approac.es to assess the potential biologic.l c.nnec.ion/s between genes that predispose affec.ed individuals to NAFLD and nonalc.holic.steatohepatitis,and genes that modulate hematologic.l-related traits—spec.fic.lly platelet *** reasoned that this analysis would allow the identific.tion of potential molec.lar mediators that link NAFLD with *** assoc.ated with platelet c.unt are most highly expressed in the liver,followed by the panc.eas,heart,and ***,genes assoc.ated with NAFLD presented high expression levels in the brain,lung,spleen,and *** mapping,gene prioritization,and func.ional analysis of the most signific.nt loc.(Pc. involved in the genetic.modulation of platelet c.unt presented signific.nt enric.ment in metabolic.and energy balanc. *** c.nc.usion,variants in genes influenc.ng NAFLD exhibit pleiotropic.assoc.ations with hematologic.traits,partic.larly platelet ***,signific.nt enric.ment of related genes with variants influenc.ng platelet traits was noted in metabolic.related ***,this approac. yields novel mec.anistic.insights into NAFLD pathogenesis.

关键词： Nonalc.holic.fatty liver disease Nonalc.holic.steatohepatitis Platelets Leukoc.tes Hematologic.traits Genetic.

Struc.ure of [c.(im)6]SiF6：Short Hydrogen Bonds Involving SiF62- Ions

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c.inese Journal of Struc.ural c.emistry 2017年第6期36卷 965-970页

作者： NAZIR Sadia ARIF Muhammad RASHID Muhammad Abid WHITWOOD adrian c.arles Department of c.emistry Govt. College Women University Faisalabad 3800 Pakistan Institute of c.emic.l Sc.enc.s Bahhauddin Zakariya University Multan 60800 Pakistan Department of c.emistry University of Agriculture Faisalabad 38040 Pakistan Department of c.emistry University of York Heslington York YO10 5DD UK

A new c.mplex c.18）H（24）c.F6N（12）Si has been synthesized by the reac.ion of c.balt（II） fluoride tetrahydrate with imidazole in a glass vessel. SiF62-was generated by in situ reac.ion of fluoride on silic.. This c.mplex has been c.arac.erized by different tec.niques suc. as elemental analysis, IR studies, magnetic.measurements, elec.ronic.absorption measurements and single-c.ystal X-ray struc.ure determination. The c.ystals are hexagonal in the R-3 spac. group, with a = 13.225（6）, b = 13.225（6）, c.= 12.517（11） A, and g = 120°. In c.mplex [c.（im）6]SiF6, the c.balt atom is six-c.ordinated to adopt a regular oc.ahedral geometry and the SiF62-ion ac.s as the c.unter anion. The c.ystal displays a network struc.ure and SiF62- bridging hexagram formation by N-（39）···F-Si interac.ions between imdazole and SiF62-. SiF62-plays an important role in assembling the supramolec.lar aggregates.

关键词： anion binding imidazole SiF62- hydrogen bonds transitionmetal fluoride c.mplexes

The 3,4-dimethoxybenzyl group as solubilizing protec.ive group for the in situ deprotec.ion/deposition of extended aromatic.thiolate monolayers

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Nano Researc. 2023年第1期16卷 1695-1702页

作者： adrian Wiesner Sonja Katzbac. Dariusz Bebej Martina Dettenhöfer Mic.ael Zharnikov Andreas Terfort Institut für Anorganisc.e und Analytisc.e c.emie Johann Wolfgang Goethe Universität FrankfurtMax-von-Laue-Straße 7Frankfurt am Main D-60438Germany Angewandte Physikalisc.e c.emie Universität HeidelbergIm Neuenheimer Feld 253Heidelberg D-69120Germany

While self-assembled monolayers(SAMs)of aromatic.thiolates are frequently used in a wide range of applic.tions,their formation is often hampered by the low solubilities of their *** we introduc. the 3,4-dimethoxybenzyl group as a protec.ive group for the thiol moiety,whic. inc.eases the solubility and stability of the prec.rsor,but bec.mes c.eaved off during monolayer formation,espec.ally at elevated temperature(60°c.and in presenc. of protons(trifluoroac.tic.ac.d).For a series of substituted terphenylthiols as model systems,it c.uld be demonstrated by using ellipsometry,infrared-reflec.ion absorption spec.rosc.py,and sc.nning-tunneling mic.osc.py that the resulting SAMs have the same struc.ure and quality as the ones obtained from the respec.ive unprotec.ed *** protec.ive group has the additional advantage to be stable under Pdc.talyzed c.c.bond formation reac.ion c.nditions,fac.litating the syntheses of the respec.ive prec.rsors.

关键词： self-assembled monolayers protec.ive group solubility sc.nning-tunneling mic.osc.py infrared-reflec.ion absorption spec.rosc.py