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和AC/DC乐队一起打鼓

2013年

作者：阿德里安·霍普金斯（adrian hopkins）

本书主要内容包括：爵士鼓记谱符号、回到黑暗、下流胚子、那些摇滚的人，我们向您致敬、地狱钟声、地狱公路、摇滚难精、来点摇滚吧等。

ISBN: (纸本)9787549526277

本书主要内容包括：爵士鼓记谱符号、回到黑暗、下流胚子、那些摇滚的人，我们向您致敬、地狱钟声、地狱公路、摇滚难精、来点摇滚吧等。

关键词：器乐曲爵士鼓世界选集

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和披头士乐队一起打鼓

2013年

作者：阿德里安·霍普金斯（adrian hopkins）

本书主要内容包括：录音注解、披头士乐队演出所用的乐器、爵士鼓记谱符号、简介、她爱你、青春岁月、我想握住你的手、我很好等。

ISBN: (纸本)9787549526260

本书主要内容包括：录音注解、披头士乐队演出所用的乐器、爵士鼓记谱符号、简介、她爱你、青春岁月、我想握住你的手、我很好等。

关键词：器乐曲爵士鼓世界选集

Basic statistics for the behavioral sciences / Kenneth D. hopkins, B.R. hopkins, Gene V. Glass. 3rd ed.

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Basic statistics for the behavioral sciences / Kenneth D. Ho...

1996年

作者： Kenneth D. hopkins B.R. hopkins Gene V. Glass.

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和你喜欢的鼓手一起打鼓

2014年

作者：（英）阿德里安·霍普金斯（adrian hopkins）

本书主要内容包括：一定要相信、现在好了、活在祈祷中、超越这感觉、阿拉巴马甜蜜的家、自从你离开之后等。……

ISBN: (数字)9787549548668

ISBN: (纸本)9787549548668

本书主要内容包括：一定要相信、现在好了、活在祈祷中、超越这感觉、阿拉巴马甜蜜的家、自从你离开之后等。……

关键词：爵士鼓器乐曲

Sonicating bees demonstrate flexible pollen extraction without instrumental learning

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Current Zoology 2019年第4期65卷 425-436页

作者： Callin M. Switzer Avery L. Russell Daniel R. Papaj Stacey A. Combes Robin hopkins Department of Organismic and Evolutionary Biology Harvard University Cambridge MA USA Arnold Arboretum Harvard University Boston MA USA Department of Ecology and Evolutionary Biology University of Arizona Tucson AZ USA Department of Neurobiology Physiology and Behavior University of California at Davis Davis CA USA Department of Biology and eScience Institute University of Washington Seattle WA USA Department of Biological Sciences University of Pittsburgh Pittsburgh PA USA

Pollen collection is necessary for bee survival and important for flowering plant reproduction, yet if and how pollen extraction motor routines are modified with experience is largely unknown. Here, we used an automated reward and monitoring system to evaluate modification in a common pollen-extraction routine, floral sonication. Through a series of laboratory experiments with the bumblebee, Bombus impatiens, we examined whether variation in sonication frequency and acceleration is due to instrumental learning based on rewards, a fixed behavioral response to rewards, and/or a mechanical constraint. We first investigated whether bees could learn to adjust their sonication frequency in response to pollen rewards given only for specified frequency ranges and found no evidenee of instrumental learning. However, we found that absenee versus receipt of a pollen reward did lead to a predictable behavioral resp on se, which depe nded on bee size. Fin ally, we found some evide nee of mechanical con straints, in that flower mass affected sonication acceleration (but not frequency) through an interaction with bee size. In generalz larger bees showed more flexibility in sonication frequency and acceleration, potentially reflecting a size-based constraint on the range over which smaller bees can modify frequency and accelerati on. Overall our results show that although bees did not display instrumental learning of sonication frequency, their sonication motor routine is nevertheless flexible.

关键词： Bombus impatiens buzz pollination foraging innate behavior learned behavior Solanum

Prognostic model of survival outcomes in non-small cell lung cancer patients initiated on afatinib: pooled analysis of clinical trial data

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Cancer Biology & Medicine 2019年第2期16卷 341-349页

作者： Ashley M. hopkins Adel Shahnam Sasha Zhang Chris S. Karapetis Andrew Rowland Michael J. Sorich Flinders Centre for Innovation in Cancer Department of Clinical Pharmacology College of Medicine and Public Health Flinders University Adelaide 5042 Australia The Canberra Hospital Garran 2605 Australia

Objective: Several predictors of survival have been identified in EGFR-positive non-small cell lung cancer(NSCLC) patients treated with first generation EGFR inhibitors. Prognostic models of survival outcomes with afatinib have not been ***: A prognostic tool for overall survival(OS)/progression free survival(PFS) based on pre-treatment clinicopathological factors was developed for EGFR-positive advanced NSCLC patients treated with first-line afatinib using penalised regression of individual-participant data from LUX-Lung 3 and 6(n = 468). Favourable, intermediate and poor risk groups were identified and externally validated using LUX-Lung 1(n = 390) and LUX-Lung 2(n = 129) trials that initiated afatinib following previous chemotherapy or EGFR inhibitor ***: Discriminative performance was good in the development and validation cohorts. For patients treated with first-line afatinib, the median OS for the favourable, intermediate and poor risk groups were > 47.7, 29.3 and 16.4 months, respectively, and the median PFS were 17.3, 13.2 and 8.3 months, respectively. The improvement in median OS with afatinib use compared to chemotherapy was > 12.4 months for the favourable risk group, whereas no OS benefit was apparent for the poor risk group. The improvement in median PFS with afatinib use compared to chemotherapy was 10.2 months for the favourable risk group and 3.2 months for the poor risk ***: A prognostic tool was developed and validated to identify favourable, intermediate and poor risk groups for OS/PFS in EGFR-positive advanced NSCLC patients treated with afatinib. The prognostic groups can inform the likely absolute OS/PFS benefit expected from afatinib compared to chemotherapy in first-line treatment.

关键词： Afatinib non-small cell lung cancer prognostic model

The role of RAD9 in tumorigenesis

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分子细胞生物学报:英文版 2011年第1期3卷 39-43页

作者： Howard B.Lieberman Joshua D.Bernstock Constantinos G.Broustas Kevin M.hopkins Corinne Leloup Aiping Zhu Center for Radiological Research Columbia University College of Physicians and Surgeons630 W.168th St.New YorkNY 10032USA Department of Environmental Health Sciences Mailman School of Public Health722 W.168th St.New YorkNY 10032USA

RAD9 regulates multiple cellular processes that influence genomic integrity,and for at least some of its functions the protein acts as part of a heterotrimeric complex bound to HUS1 and RAD1 ***9 participates in DNA repair,including base excision repair,homologous recombination repair and mismatch repair,multiple cell cycle phase checkpoints and *** addition,functions including the transactivation of downstream target genes,immunoglobulin class switch recombination,as well as 3′–5′exonuclease activity have been *** RAD9 expression has been linked to breast,lung,thyroid,skin and prostate tumorigenesis,and a cause–effect relationship has been demonstrated for the latter ***,human RAD9 overproduction correlates with prostate cancer whereas deletion of Mrad9,the corresponding mouse gene,in keratinocytes leads to skin *** results reveal that RAD9 protein can function as an oncogene or tumor suppressor,and aberrantly high or low levels can have deleterious health *** is not clear which of the many functions of RAD9 is critical for carcinogenesis,but several alternatives are considered herein and implications for the development of novel cancer therapies based on these findings are examined.

关键词： RAD9 tumor suppressor oncogene tumorigenesis cell cycle checkpoints DNA repair

Mario Paint： An Accessible Environment of Musical Creativity and Sound Exploration

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Journal of Literature and Art Studies 2015年第10期5卷 847-858页

作者： Dr. Christopher hopkins Long Island University Brookville USA Five Towns College Dix Hills USA

Mario Paint, the 1992 Nintendo game for the Super NES, remains an accessible environment for musical creativity and sound exploration within its music mode. Although developed for a gaming system, the game＇s music mode is a streamlined tool built upon basic music theory and music composition. Through familiar video game sounds and icon and Westem music notation, players are able to compose chipttme works and explore the nature of sound through an inviting interface. Similar music composition software upgrades the process of composition established in Mario Paint, allowing for digital distribution and dissemination. Mario Paint continues to inspire new projects in the areas of video games and scholastic studies. Mario Paint and its successors are very reasonable entry-level programs for chiptune composers and fledgling music students

关键词： music composition Super NES Nintendo music theory music production sound chip

Gene Screen for Breast Cancer Better than Pathologist's "Eye"

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当代外语研究 2006年第11期 6-7页

作者： Johns hopkins 姜彬 Medical Institutions

医学研究人员最近发现了诊断肿瘤的新方法。根据约翰·霍普金斯大学医学研究中心的实验,研究人员通过从人体器官的体液中采集到某种特殊类别的细胞,并由其DNA信息中筛离出与肿瘤有关的化学成分。这种诊断方式较以往的病理学分析方式又... 详细信息

医学研究人员最近发现了诊断肿瘤的新方法。根据约翰·霍普金斯大学医学研究中心的实验,研究人员通过从人体器官的体液中采集到某种特殊类别的细胞,并由其DNA信息中筛离出与肿瘤有关的化学成分。这种诊断方式较以往的病理学分析方式又有了新的突破。

关键词：研究人员肿瘤医学研究中心霍普金斯大学特殊类化学成分新方法人体器官病理学家诊断方式