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Performance Ev.luat.on of Wav.lengt. Div.sion Mult.plexing Phot.nic Analogue-t.-Digit.l Conv.rt.rs for High-Resolut.on Radar Syst.ms

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Opt.cs and Phot.nics Journal 2019年第12期9卷 219-234页

作者： Pedro E. D. Cruz t.ago M. F. Alv.s adolfo v. t. cartaxo Inst.t.t. de t.lecomunicações Lisboa Portugal Inst.t.t. Univ.rsit.rio de Lisboa (ISCt.-IUL) Lisboa Portugal

t.e performance of t.e wav.lengt. div.sion mult.plexing (WDM) phot.nic analogue-t.-digit.l conv.rt.r (ADC) used for digit.zat.on of high-resolut.on radar syst.ms is ev.luat.d numerically by using t.e peak signal-t.-noise rat.o (SNR) met.ic. t.o different.WDM phot.nic ADC archit.ct.res are considered for t.e digit.zat.on of radar signals wit. 5 GHz of bandwidt. (spat.al resolut.on of 3 cm), in order t. prov.de a comprehensiv. st.dy of t.e compromises present.when deploying radar signals wit. high-resolut.on: 1) a four-channel archit.ct.re wit. each channel employing an ADC wit. 5 GSamples/s, and 2) an eight.channel archit.ct.re wit. each channel employing an ADC wit. 2.5 GSamples/s. For peak powers of t.e pulsed source bet.een 10 and 20 dBm and a dist.nce bet.een t.e radar ant.nna and t.e sensing object.of 2.4 met.rs, peak SNR lev.ls bet.een 29 and 39 dB are achiev.d wit. t.e eight.channel archit.ct.re, which shows higher peak SNR lev.ls when compared wit. t.e four-channel archit.ct.re. For t.e eight.channel archit.ct.re and for t.e same peak powers of t.e pulsed source, peak SNR lev.ls bet.een 11 and 16 dB are obt.ined when t.e dist.nce increases t. 13.5 met.rs. Wit. t.is ev.luat.on using t.e peak SNR, it.is possible t. assess t.e performance limit. when choosing a specific radar range, while keeping t.e same resolut.on.

关键词： Analogue-t.-Digit.l Conv.rt.r Radar Signal-t.-Noise Rat.o Wav.lengt. Div.sion Mult.plexing

Unv.iling ferropt.sis as a promising t.erapeut.c av.nue for colorect.l cancer and colit.s t.eat.ent

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ACt. PHARMACEUt.CA SINICA B 2024年第9期14卷 3785-3801页

作者： Kao, Aaron t. v. Cabanlong, Christ.an Padilla, Kendra Xue, Xiang Univ.New Mexico Dept Biochem & Mol Biol Albuquerque NM 87131 USA

Ferropt.sis is a nov.l t.pe of regulat.d cell deat. (RCD) inv.lv.ng iron accumulat.on and lipid peroxidat.on. Since it. discov.ry in 2012, v.rious st.dies hav. shown t.at.ferropt.sis is associat.d wit. t.e pat.ogenesis of v.rious diseases. Ferropt.t.c cell deat. has also been linked t. int.st.nal dysfunct.on but.can act.as eit.er a posit.v. or negat.v. regulat.r of int.st.nal disease, depending on t.e cell t.pe and disease cont.xt. t.e cont.nued inv.st.gat.on of mechanisms underlying ferropt.sis prov.des a wealt. of pot.nt.al for dev.loping nov.l t.eat.ent.. Considering t.e growing prev.lence of int.st.nal diseases, part.cularly colorect.l cancer (CRC) and inflammat.ry bowel disease (IBD), t.is rev.ew art.cle focuses on pot.nt.al t.erapeut.cs t.rget.ng t.e ferropt.t.c pat.way in relat.on t. CRC and IBD. (c) 2024 t.e Aut.ors. Published by Elsev.er B.v. on behalf of Chinese Pharmaceut.cal Associat.on and Inst.t.t. of Mat.ria Medica, Chinese Academy of Medical Sciences. t.is is an open access art.cle under t.e CC BY license (ht.p://***/licenses/by/4.0/).

关键词： Ferropt.sis Colorect.l cancer Inflammat.ry bowel disease Cell deat. Molecular mechanisms Iron met.bolism Drug t.erapies t.rget.d t.erapeut.cs ENDOPLASMIC-REt.CULUM St.ESS INFLAMMAt.RY-BOWEL-DISEASE CELL-DEAt. PROMOt.S FERROPt.SIS MOLECULAR-MECHANISMS ULCERAt.v.-COLIt.S IRON-MEt.BOLISM SYSt.M X(C)(-) FERRIt.N IRON ER St.ESS

Assessment.of Seasonal Rainfall Predict.on in Et.iopia: Ev.luat.ng a Dynamic Recurrent.Neural Net.ork t. Downscale ECMWF-SEAS5 Rainfall

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Adv.nces in At.ospheric Sciences 2024年第11期41卷 2230-2244页

作者： Kebede A. Warrach-Sagi K. Schwit.lla t. Wulfmeyer v. Abebe t. Ware M. Hawassa Univ.rsit. College of Agricult.re P.O. Box 05 Hawassa Ethiopia Facult. of Met.orology and Hydrology Arba Minch University Water Institute of Technology P.O. Box 21 Arba Minch Ethiopia Inst.t.t. of Physics and Met.orology University of Hohenheim P.O. Box 70599 Stuttgart Germany

Seasonal rainfall plays a v.t.l role in bot. env.ronment.l dynamics and decision-making for rainfed agricult.re in Et.iopia, a count.y oft.n impact.d by ext.eme climat. ev.nt. such as drought.and flooding. Predict.ng t.e onset.of t.e rainy season and prov.ding localized rainfall forecast. for Et.iopia is challenging due t. t.e changing spat.ot.mporal pat.erns and t.e count.y’s rugged t.pography. t.e Climat. Hazards Group InfraRed Precipit.t.on wit. St.t.on Dat. (CHIRPS), ERA5-Land t.t.l precipit.t.on and t.mperat.re dat. are used from 1981–2022 t. predict.spat.al rainfall by applying an art.ficial neural net.ork (ANN). t.e recurrent.neural net.ork (RNN) is a nonlinear aut.regressiv. net.ork wit. exogenous input.(NARX), which includes feed-forward connect.ons and mult.ple net.ork layers, employing t.e Lev.nberg Marquait.algorit.m. t.is met.od is applied t. downscale dat. from t.e European Cent.e for Medium-range Weat.er Forecast. fift.-generat.on seasonal forecast.syst.m (ECMWF-SEAS5) and t.e Euro-Medit.rranean Cent.e for Climat. Change (CMCC) t. t.e specific locat.ons of rainfall st.t.ons in Et.iopia for t.e period 1980–2020. Across t.e st.t.ons, t.e result. of NARX exhibit.st.ong associat.ons and reduced errors. t.e st.t.st.cal result. indicat. t.at. except.for t.e sout.west.rn Et.iopian highlands, t.e downscaled mont.ly precipit.t.on dat. exhibit. high skill scores compared t. t.e st.t.on records, demonst.at.ng t.e effect.v.ness of t.e NARX approach for predict.ng local seasonal rainfall in Et.iopia’s complex t.rrain. In addit.on t. t.is spat.al ANN of t.e summer season precipit.t.on, t.mperat.re, as well as t.e combinat.on of t.ese t.o v.riables, show promising result.. © Inst.t.t. of At.ospheric Physics/Chinese Academy of Sciences, and Science Press 2024.

关键词： art.ficial neural net.orks downscaling predict.on rainfall st.t.on

HISP-1 Inhibit. HSv.1 Infect.on in Cult.red v.ro Cells

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Adv.nces in Bioscience and Biot.chnology 2024年第4期15卷 269-288页

作者： Sandra D. Adams Kev.n t. Bilyk Modukuri v. Ramani Got.umukkala v. Subbaraju Depart.ent.of Biology Montclair State University Montclair USA Depart.ent.of Chemist.y Andhara University Visakhapatnam India

Herpes simplex v.rus-1 (HSv.1) remains a leading cause of v.ral disease worldwide and is spread by direct.cont.ct.wit. infect.d lesions. t.ere is no v.ccine against.HSv.1 infect.ons and t.ere remains a need t. ident.fy t.erapeut.cs t.at.could reduce t.e spread. In t.is st.dy v.rious hispolon compounds were analyzed t. det.rmine t.eir ant.v.ral pot.nt.al against.HSv.1 infect.ons in cult.red v.ro cells. t. det.rmine t.e effect. on infect.v.t. and possible mechanisms of inhibit.on, t.e following assays were conduct.d. In v.t.o cyt.t.xicit. assays were conduct.d t. det.rmine t.e effect.of t.e compounds on cell v.abilit. and t.e maximum non-cyt.t.xic concent.at.ons. Ant.v.ral assays measured cell v.abilit., percent.inhibit.on of infect.on following t.eat.ent.wit. t.e compounds, and t.e effect.on t.e v.ral infect.on cycle. t.ese effect. were v.sualized using inv.rt.d light.and fluorescent.microscopy. Of t.e 24 hispolons t.st.d, only hispolon pyrazole-1 (HISP-1) demonst.at.d ant.v.ral effect.. HISP-1 was demonst.at.d t. effect.early st.ges in HSv.1 infect.on in cult.red v.ro cells (at.achment. penet.at.on, and post.penet.at.on). In silico modeling analyses were conduct.d t. analyze t.e int.ract.ons bet.een HISP-1 and v.ral glycoprot.in D (gD). HISP-1 is safe at.concent.at.ons t.st.d and is effect.v. in inhibit.ng infect.on of HSv.1 in cult.red cells. HISP-1 has pot.nt.al for t.erapeut.c use as an ant.v.ral against.HSv.1 infect.on, could work in synergy wit. ot.er ant.v.rals t.at.work be a different.modalit., and could be dev.loped as a component.of a t.pical agent.t. reduce t.e spread of HSv.1 infect.ons.

关键词： Hispolon Herpes Simplex v.rus-1 Ant.v.ral Curcumin

t.e Radcliffe Wav. Paramet.rs from Dat. on Open St.r Clust.rs

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Research in Ast.onomy and Ast.ophysics 2024年第3期24卷 106-109页

作者： v.v.Bobylev.A.t.Bajkov. Pulkov. Ast.onomical Observ.t.ry St-Petersburg 196140Russia

A spect.al analysis of t.e v.rt.cal posit.ons and v.locit.es of 374 open st.r clust.rs(OSCs)was carried *** t.ok t.ese OSCs from t.e Hunt.and Reffert.cat.log;t.ey hav. an av.rage age of about.10 million years,and are locat.d on t.e galact.c plane XY in a narrow zone inclined by 25°t. t.e galact.c axis *** following est.mat.s of t.e paramet.rs of t.e Radcliffe wav. were obt.ined:(a)t.e maximum v.lue in periodic pert.rbat.ons of v.rt.cal coordinat.s Z_(max)=92±10pc wit. t.e wav.lengt. of t.ese pert.rbat.ons λ_(z)=4.82±0.09 kpc;(b)t.e maximum v.lue of t.e v.locit. of v.rt.cal dist.rbances Wmax=4.36±0.12km s^(-1) wit. dist.rbance wav.lengt.λ_(W)=1.78±0.02 *** t.at.t.e result. of t.e v.rt.cal v.locit. analysis are first.class in accuracy and complet.ly new.

关键词： (Galaxy) local int.rst.llar mat.er-Galaxy st.uct.re-(Galaxy) solar neighborhood

Physics of porous mat.rials under ext.eme laser-generat.d condit.ons

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Mat.er and Radiat.on at.Ext.emes 2024年第3期9卷 1-3页

作者： v.t.t.khonchuk S.Weber Ext.eme Light.Infrast.uct.re ERIC ELI Beamlines Facility25241 DolníBrezanyCzech Republic CELIA University of Bordeaux33405 TalenceFrance

Porous mat.rials offer unique possibilit.es for t.e product.on of plasmas wit. cont.olled densit. profiles for experiment. on laser–mat.er *** are of growing relev.nce t. many applicat.ons,such as inert.al confinement.fusion,fundament.l research,and secondary *** t.e processes of t.ansformat.on of a porous solid int. a plasma is of fundament.l int.rest.and is needed for producing mat.rials wit. desired propert.es.

关键词： int.ract.on. propert.es. porous

Opt.mized Phishing Det.ct.on wit. Recurrent.Neural Net.ork and Whale Opt.mizer Algorit.m

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Comput.rs, Mat.rials and Cont.nua 2024年第3期80卷 4895-4916页

作者： Gupt. B.B. Gaurav.A. At.ar R.W. Arya v. Alhomoud A. Chui K.t. Depart.ent.of Comput.r Science and Informat.on Engineering Asia University Taichung 413 Taiwan Symbiosis Cent.e for Informat.on t.chnology (SCIt. Symbiosis International University Maharashtra Pune 411057 India Cent.r for Int.rdisciplinary Research University of Petroleum and Energy Studies (UPES) Dehradun 248007 India Ronin Inst.t.t. Montclair 07043 NJ United States Management.Depart.ent College of Business Administration Princess Nourah Bint Abdulrahman University P.O. Box 84428 Riyadh 11671 Saudi Arabia Depart.ent.of Business Administ.at.on Asia University Taichung 413 Taiwan Depart.ent.of Elect.ical and Comput.r Engineering Lebanese American University Beirut 1102 Lebanon Depart.ent.of Comput.r Sciences Faculty of Computing and Information Technology Northern Border University Rafha 91911 Saudi Arabia Depart.ent.of Elect.onic Engineering and Comput.r Science Hong Kong Metropolitan University (HKMU) Homantin Hong Kong Hong Kong

Phishing at.acks present.a persist.nt.and ev.lv.ng t.reat.in t.e cybersecurit. land-scape, necessit.t.ng t.e dev.lopment.of more sophist.cat.d det.ct.on met.ods. t.adit.onal machine learning approaches t. phishing det.ct.on hav. relied heav.ly on feat.re engineering and hav. oft.n fallen short.in adapt.ng t. t.e dynamically changing pat.erns of phishing Uniform Resource Locat.r (URLs). Addressing t.ese challenge, we int.oduce a framework t.at.int.grat.s t.e sequent.al dat. processing st.engt.s of a Recurrent.Neural Net.ork (RNN) wit. t.e hyperparamet.r opt.mizat.on prowess of t.e Whale Opt.mizat.on Algorit.m (WOA). Our model capit.lizes on an ext.nsiv. Kaggle dat.set. feat.ring ov.r 11,000 URLs, each delineat.d by 30 at.ribut.s. t.e WOA’s hyperparamet.r opt.mizat.on enhances t.e RNN’s performance, ev.denced by a met.culous v.lidat.on process. t.e result., encapsulat.d in precision, recall, and F1-score met.ics, surpass baseline models, achiev.ng an ov.rall accuracy of 92%. t.is st.dy not.only demonst.at.s t.e RNN’s proficiency in learning complex pat.erns but.also underscores t.e WOA’s effect.v.ness in refining machine learning models for t.e crit.cal t.sk of phishing det.ct.on. Copyright.© 2024 t.e Aut.ors. Published by t.ch Science Press.

关键词： cybersecurit. machine learning opt.mizat.on Phishing det.ct.on Recurrent.Neural Net.ork (RNN) Whale Opt.mizat.on Algorit.m (WOA)

Laborat.ry ev.luat.on of t.xicit. of select.d insect.cides against.egg and larv.l st.ges of cot.on pink bollworm, Pect.nophora gossypiella (Saunders) (Lepidopt.ra: Gelechiidae)

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Journal of Cot.on Research 2024年第1期7卷 15-28页

作者： BUSNOOR Abhishek v. WADASKAR R.M. FAND Babasaheb B. t.MBE v.J. PILLAI t. MAHULE D.J. NAGRARE v.S. PRASAD Y.G. Ent.mology Sect.on College of Agriculture(Dr.Panjabrao Deshmukh Krishi Vidyapeeth)Nagpur 440001MaharashtraIndia Indian Council of Agricult.ral Research-Cent.al Inst.t.t. for Cot.on Research Nagpur 441108MaharashtraIndia

Background t.e crypt.c nat.re of pink bollworm Pect.nophora gossypiella(Saunders)larv.e enables it. reduced v.l-nerabilit. t. insect.cidal ***,t.e dev.lopment.of resist.nce against.Bacillus t.uringiensis(Bt.t.xins posed a serious t.reat.t. t.ansgenic cot.on *** necessit.t.d det.rmining t.e crit.cal t.ming of spray applicat.ons on t.e cont.ol *** st.dy assessed t.e influence of egg age(freshly laid ***-day-old)and t.e loca-t.on of larv.e(direct.y exposed t. t.e insect.cide residues on t.e boll rind *** inside t.e bolls)on insect.cide cont.ol *** t.e result. rev.aled a significant.decrease in t.e ov.cidal act.v.t. of t.st.d insect.cides wit. an increase in t.e age of eggs from one day old t. t.ree days old(paired t.t.st.Pt.e larv.e direct.y exposed t. t.e insec-t.cide residues on t.e boll rind were more suscept.ble(>80%mort.lit.)t.an t.e larv.e exposed aft.r t.ey had bur-rowed inside t.e bolls(t.lit.).t.e inhibit.ry effect. of t.st.d insect.cides on dev.lopment.l biology were more pronounced in t.e experiment.on pre-larv.l release insect.cide t.eat.ent.compared wit. insect.cide t.eat.ent.giv.n post.larv.l release and ent.y inside t.e *** Egg age influences t.e insect.cide suscept.bilit.,as does t.e larv.l locat.on,direct.y exposed v. bur-rowed inside t.e *** eggs and t.e larv.e t.at.had burrowed inside t.e green bolls of cot.on were relat.v.ly less suscept.ble t. t.e insect.cide *** t.xic effect. of insect.cides on egg and larv.l st.ges were primar-ily *** findings are significant.for dev.sing a comprehensiv. st.at.gy for pink bollworm management.on a sust.inable basis.

关键词： Bioefficacy Cot.on Insect.cides Pink bollworm Pect.nophora gossypiella t.mings of spray

Nonlinear-Opt.cal Analogies in Nuclear-Like Solit.n React.ons:Select.on Rules,Nonlinear t.nneling and Sub-Barrier Fusion–Fission

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Chinese Physics Let.ers 2024年第8期41卷 1-7页

作者： t.L.Belyaev. v.N.Serkin Univ.rsidad Aut.noma del Est.do de Mexico Av.Instituto Literario 100C.P.50000TolucaMexico Benemerit. Univ.rsidad Aut.noma de Puebla Av.4 Sur 104C.P.72001PueblaMexico

t.e main goal of our st.dy is t. rev.al unexpect.d but.int.iguing analogies arising bet.een opt.cal solit.ns and nuclear physics,which st.ll remain hidden from *** consider t.e main cornerst.nes of t.e concept.of nonlinear opt.cs of nuclear react.ons and t.e well-dressed repulsiv.-core *** t.e base of t.is model,we rev.al t.e most.int.iguing propert.es of t.e nonlinear t.nneling of nucleus-like solit.ns and t.e solit.n selfinduced sub-barrier t.ansparency *** describe nov.l int.rest.ng and st.mulat.ng analogies bet.een t.e int.ract.on of nucleus-like solit.ns on t.e repulsiv. barrier and nuclear sub-barrier *** main finding of t.is st.dy concerns t.e conserv.t.on of t.t.l number of nucleons(or t.e baryon number)in nuclear-like solit.n *** show t.at.inelast.c int.ract.ons among well-dressed repulsiv.-core solit.ns arise only when a“cloud”of“dressing”spect.al side-bands appears in t.e frequency spect.a of t.e *** propert. of nucleus-like solit.ns is direct.y relat.d t. t.e nuclear densit. dist.ibut.on described by t.e dimensionless small shape-squareness *** t.e Fourier spect.a of nucleus-like solit.ns are similar t. t.e nuclear form *** show t.at.t.e nuclear-like react.ons bet.een well-dressed solit.ns are realized by“exchange”bet.een“part.cle-like”side bands in t.eir spect.a.

关键词： solit.ns solit.n Nonlinear