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Belt and Road Initiative Tax Journal 2023年第2期4卷 64-68页

作者： Robert Danon Daniel Gutmann Guglielmo Maisto adolfo martín jiménez University of Lausanne CMS Francis Lefebvre Avocats France Maisto e Associati Italy University of Cadiz Spain

The successful implementation of the Global Anti-Base Erosion(GloBE)rules on a global scale cannot be achieved without an international effective dispute prevention and resolution ***,the development of a dispute prevention and resolution framework for the GloBE rules faces significant *** article offers two possible options for an effective dispute prevention and resolution mechanism:a model based on reciprocal domestic legislations and the multilateral convention model.

关键词： Global Anti-Base Erosion rules Dispute prevention and resolution mechanism Multilateral convention

Portal Venous Thrombosis and Splenic Hemangioma, Secondary to Acute Pancreatitis: Case Report

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Open Journal of Gastroenterology 2024年第1期14卷 11-17页

作者： Gustavo adolfo Hernández Valdez Harvey Yair Zamora Veliz Estefany Gilberty Mendoza Verdin Quitzia Mayanim Rentería Fonseca Itzel Velázquez Viniegra Janette Alejandra Gamiño Gutierrez Diana Rita Velázquez jimenez Florencio Favian Andrade Luis Fernando Baez Bustos Jorge Morales Rojas María Jacqueline martínez Tejeda Graciela Gaddy Robles martínez Juan Antonio Contreras Escamilla Departamento de Medicina Interna ISSSTE Tepic General Hospital APP Tepic Nayarit México General Surgery Department ISSSTE Tepic General Hospital APP Tepic Nayarit México Hospital Civil Fray Antonio Alcalde Guadalajara Jalisco México

We present an unusual case of portal vein thrombosis with a splanchnic hemangioma secondary to acute biliary pancreatitis. We report a 45-year-old patient, who has systemic arterial hypertension in treatment, was admitted for abdominal pain in the epigastrium, with irradiation to the right hypochondrium, accompanied by nausea and vomiting of 10 occasions of bile content, physical examination with pain in the right hypochondrium, Murphy positive. We have laboratory studies with a lipase of 788, so a diagnosis of pancreatitis is made with an etiology to be determined. The laboratories suggestive of acute biliary pancreatitis (lipase 788.71);an imaging study was subsequently performed (ultrasonography) with the result of stone in the common bile duct. A laparoscopy was performed with relative improvement, so he was discharged and returned 20 days after surgery due to abdominal pain of the same intensity in the left hypochondrium. Ending his hospitalization with a splenectomy for splenic hemangioma with portal vein thrombosis.

关键词： Pancreatitis Esplenic Hemangioma Esplenectomy Portal Vein Thrombosis Surgery

BaTiO3 solid solutions co-doped with Gd3+ and Eu3+:Synthesis,structural evolution and dielectric properties

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Journal of Rare Earths 2024年第10期42卷 1920-1926页

作者： R.martínez-López M.Pérez-Labra J.A.Romero-Serrano F.R.Barrientos-Hernández M.Reyes-Pérez M.I.Valenzuela-Carrillo G.Urbano-Reyes V.E.Reyes-Cruz G.I.Dávila-Pulido Academic Area of Earth Sciences and Materials Autonomous University of Hidalgo State Metallurgy and Materials Department ESIQIE-IPNUPALM Autonomous University of Coahuila Boulevard Adolfo López Mateos S/n

In this paper,the synthesis,structural evolution,and dielectric properties of BaTiO3solid solutions codoped with rare earth elements(Gd3+and Eu3+) prepared using the solid-state reaction method are *** pure precursor powders of BaCl3,TiO2,Gd2O3,and Eu2O3were mixed in stoichiometric proportions,ground in an agate mortar before being uniaxially pressed at 250 MPa and sintered at 1300℃ in air atmosphere for 6 h to obtain Ba1-3xGd2xTi1-3xEu4xO3（x=0,0.0015,0.01 and0.1）.X-ray diffraction（XRD） and Rietveld's refinement results reveal the crystal phase ferroelectric tetragonal BaTiO3for the samples with x=0,0.0015 and 0.01, as well as a consistent increment in the lattice parameters caused by the *** solubility limit of Gd3+and Eu3+in the BaTiO3structure is reached for the sample with x>0.01,and the orthorhombic Eu2TiO5and monoclinic BaTi2O5secondary phases were *** Raman results show the characteristic peaks of ferroelectric tetragonal BaTiO3around 716 cm-1（LO of A1 symmetry）,515 cm-1（TO of A1 symmetry）,and 305 cm-1（B1）.The maximum relative permittivity measured at 1 kHz was recorded to be 6151.8 for the sample with x=0.0015,and a decrease in the Curie temperature to 105℃ with respect to the undoped sample was *** punctual microanalysis for the samples with x=0.0015,0.01,and 0.1 reveals grains composed of Ba,Ti,O,Gd,and Eu homogeneously distributed in the *** Ba/Ti ratios for samples with x=0.0015,0.01 and 0.1 are 2.86,2.91,and 0.68,respectively,indicating substitution at the Ti site for samples with x=0.0015 and 0.01 and a substitution at the Ba site for the sample with x=0.1.

关键词： BaTiO3 Doping Europium Gadolinium Rare earths Synthesis

Portal Venous Thrombosis and Splenic Hemangioma, Secondary to Acute Pancreatitis:Case Report

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Skeletons of 3D Surfaces Based on the Laplace-Beltrami Operator Eigenfunctions

Open Journal of Gastroenterology（肠胃病学期刊） 2024年第1期

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Applied Mathematics 2015年第2期6卷 414-420页

作者： adolfo Horacio Escalona-Buendia Lucila Ivonne Hernández-martínez Rarafel martínez-Vega Julio Roberto Murillo-Torres Omar nieto-Crisóstomo Academia de Informá tica Universidad Aut&oacute noma de la Ciudad de Mé xico Mexico City Mexico Academia de Matemá ticas Universidad Aut&oacute noma de la Ciudad de Mé xico Mexico City Mexico

In this work we describe the algorithms to construct the skeletons, simplified 1D representations for a 3D surface depicted by a mesh of points, given the respective eigenfunctions of the Discrete Laplace-Beltrami Operator (LBO). These functions are isometry invariant, so they are independent of the object’s representation including parameterization, spatial position and orientation. Several works have shown that these eigenfunctions provide topological and geometrical information of the surfaces of interest [1] [2]. We propose to make use of that information for the construction of a set of skeletons, associated to each eigenfunction, which can be used as a fingerprint for the surface of interest. The main goal is to develop a classification system based on these skeletons, instead of the surfaces, for the analysis of medical images, for instance.

关键词： Skeleton Centerline Discrete Laplace-Beltrami Operator Eigenfunctions Graph Theory

Improvement of transfection with reprogramming factors in urine-derived cells

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BIOCELL 2020年第3期44卷 401-409页

作者： OLIVIA A.ROBLES-RODRÍGUEZ MARÍA J.LOERA-ARIAS JOSÉJ.PÉREZ-TRUJILLO ARnULFO VILLAnUEVA-OLIVO ERnESTO PICÓn-GALInDO LAURA VILLARREAL-martÍnez adolfo SOTO-DOMÍnGUEZ HUMBERTO RODRÍGUEZROCHA ARACELY GARCÍA-GARCÍA ODILA SAUCEDO-CÁRDEnAS ROBERTO MOnTES DE OCA-LUnA Facultad de Medicina Departamento de HistologíaUniversidad Autónoma de Nuevo LeónMonterreyC.P.64460México Hospital Universitario“Dr.JoséEleuterio González González” Servicio de HematologíaUniversidad Autónoma de Nuevo LeónMonterreyC.P.64460México Centro de Investigación Biomédica del noreste Departamento de Genética MolecularInstituto Mexicano del Seguro SocialMonterreyC.P.64720México

Human-induced pluripotent stem cells(iPSCs)are an accessible source of adult-derived,patient-specific pluripotent stem cells for use in basic research,drug discovery,disease modeling,and stem cell *** the accessibility of methods to obtain iPSCs regardless of the cell source can enhance their clinical ***,our purpose is to report a simple protocol to obtain iPS-like cells from urine-derived renal epithelial cells(RECs)using different extracellular matrices and transfection *** this study,we began by culturing urine-derived cells from healthy donors to establish a primary culture of renal epithelial cells,followed by their ***,we generated iPS-like cells by transfecting renal epithelial cells(RECs)with vectors expressing Oct4,Sox2,L-Myc,Lin-28,and Klf4,and we compared the efficacy of different extracellular matrices and transfection *** resultant iPS-like cells showed a human embryonic stem cell-like morphology and expressed the specific pluripotency markers Oct3/4,nanog,Lin28,and *** concluded that Lipofectamine Stem Cell transfection reagent is more effective than FuGEnE in obtaining iPS-like cells under the conditions ***,the three matrices are similar in their efficiency of obtaining iPS-like *** report provides an experimental protocol for obtaining and generating iPS-like cells from urine samples for further cell therapy research on different human diseases.

关键词： Reprogramming factors iPSCs Renal epithelial cells Extracellular matrix Transfection reagent

Production of Ag-ZnO powders by hot mechanochemical processing

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Transactions of nonferrous Metals Society of China 2019年第2期29卷 365-373页

作者： D.GUZMán C.AGUILAR P.ROJAS J.M.CRIADO M.J.DIánez R.ESPInOZA A.GUZMán C.martínez Departamento de Ingeniería en Metalurgia Universidad de Atacama Departamento de Ingeniería Metalúrgica y de Materiales Universidad Técnica Federico Santa María Escuela de Dise?o Universidad Adolfo Ibá?ez Instituto de Ciencias de Materiales de Sevilla C.S.I.C Departamento de Ciencia de los Materiales Universidad de Chile Laboratorio de Corrosión Instituto de QuímicaPontificia Universidad Católica de Valparaíso

Ag–CdO composites are still one of the most commonly used electrical contact materials in low-voltage applications owing to their excellent electrical and mechanical ***,considering the restriction on using Cd due to its toxicity,it is necessary to find alternative materials that can replace these *** this study,the synthesis of Ag-ZnO alloys from Ag-Zn solid solutions was investigated by hot mechanochemical *** hot mechanochemical processing was conducted in a modified attritor mill at 138℃under flowing O2 at 1200 cm3/min for 3.0 *** microstructure and phase evolution were investigated using X-ray diffractometry,field emission gun scanning electron microscopy and transmission electron *** results suggest that it is possible to complete the oxidation of Ag-Zn solid solution by hot mechanochemical processing at a low temperature and short *** novel synthesis route can produce Ag-ZnO composites with a homogeneous distribution of nanoscale ZnO precipitates,which is impossible to achieve using the conventional material processing *** the fact that the fundamental approach to improving electric contact material performance resides in obtaining uniform dispersion of the second-phase in the Ag matrix,this new processing route could open the possibility for Ag-ZnO composites to replace non-environmentally friendly Ag-CdO.

关键词： Ag-ZnO nanocomposite electrical contact material powder synthesis milling

Effects of vacuum-assisted closure and Drotrecogin alpha on inflammatory markers in severe acute pancreatitis

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Advances in Bioscience and Biotechnology 2013年第8期4卷 43-53页

作者： Oscar Arias-Carvajal José Manuel Hermosillo-Sandoval Carlos Alberto Gutiérrez-martínez Fermín Paul Pacheco-Moisés Genaro Gabriel Ortiz adolfo Daniel Rodríguez-Carrizalez Luis Miguel Román-Pintos Alejandra Guillermina Miranda-Díaz Department of Chemistry University of Guadalajara Guadalajara México Department of General Surgery Specialties Hospital National Occidental Medical Centre Social Security Institute of México Guadalajara México Department of Physiology University Health Sciences Centre University of Guadalajara Guadalajara México Intensive Care Unit Specialties Hospital National Occidental Medical Centre Social Security Institute of México Guadalajara México Occidental Biomedical Research Centre Social Security Institute of México Guadalajara México

In severe acute pancreatitis (SAP) inflammatory processes foster necrosis, cellular lysis and liberation of vasoactive substances associated with multiple organ failure. The effects of vacuum-assisted closure and Drotrecogin alpha on inflammatory cytokines were evaluated in SAP patients with infected necrosis. Methods: Forty-six patients were included in three groups: Group 1, necrosectomy and abdominal cavity washing;Group 2, necrosectomy plus vacuum-assisted closure (VAC), and Group 3, necrossectomy plus VAC plus Drotrecogin alpha. Immunoreactive IL-32, TnF-α, IL-6, TGF-β and IL-2 cytokines were quantified with ELISA method. Results: IL-32 was significantly increased in all patients, predominantly the non-survivor of Group 3 (p 0.0001). Group 2 maintained increased IL-32 levels throughout. Peak TnF-α was observed in non-survivors of Groups 1 and 2, with a frank tendency to decrease in Group 3. The IL-6 was increased, sustained throughout the study, peaking at the onset in non-survivors. At the end IL-6 tended to diminish, predominantly in survivors. TnF-α and IL-6 were significantly increased on hospitalization, with a maximum peak in non-survivors of all groups. Initial values of TGF-β were significantly increased in survivors of the three groups, and were significantly diminished in non-survivors;affecting pancreas regeneration and favoring systemic inflammation, with possible multiple-organ repercussions. IL-2 levels were elevated, predominantly in non-survivors of Group 1. There was positive correlation between the increase IL-32 and TnF-α, and negative correlation between the increase in TnF-α and decrease in TGF-β;and, a tendency for negative correlation between the IL-2 increased and TGF-β levels. Conclusion: We found a generalized, sustained inflammatory state that fosters a torpid outcome in SAP patients.

关键词： Severe Acute Pancreatitis Systemic Inflammation Proinflammatory Cytokines

Review of natural products with hepatoprotective effects

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World Journal of Gastroenterology 2014年第40期20卷 14787-14804页

作者： Eduardo Madrigal-Santillán Eduardo Madrigal-Bujaidar Isela álvarez-González María Teresa Sumaya-martínez José Gutiérrez-Salinas Mirandeli Bautista ángel Morales-González Manuel García-Luna y González-Rubio J Leopoldo Aguilar-Faisal José A Morales-González Laboratorio Medicina de Conservación Escuela Superior de Medicina Instituto Politécnico Nacional Plan de San Luis y Díaz Mirón Col. Casco de Santo Tomás Del. Miguel Hidalgo México DF 11340 México Laboratorio de Genética Escuela Nacional de Ciencias Biológicas Instituto Politécnico Nacional Unidad profesional Adolfo López Mateos Col. Lindavista Delegación Gustavo A. Madero México DF 07738 México Secretaria de Investigación y Estudios de Posgrado Universidad Autónoma de Nayarit "Ciu-dad de la Cultura Amado Nervo" Nayarit 28000 México Laboratorio de Bioquímica y Medicina Experimental División de Investigación Biomédica Centro Médico Nacional "20 de Noviembre" ISSSTE México DF 03100 México área Académica de Farmacia Instituto de Ciencias de la Salud UAEH Pachuca Hidalgo 42000 México Escuela Superior de Cómputo Instituto Politécnico Nacional Av. Juan de Dios Bátiz s/n esquina Miguel Othón de Mendizabal Unidad Profesional Adolfo López Mateos México DF 07738 Mexico Facultad de Odontología UNAM México DF 04510 Mexico

The liver is one of the most important organs in the body,performing a fundamental role in the regulationof diverse processes,among which the metabolism,secretion,storage,and detoxification of endogenous and exogenous substances are *** to these functions,hepatic diseases continue to be among the main threats to public health,and they remain problems throughout the *** enormous advances in modern medicine,there are no completely effective drugs that stimulate hepatic function,that offer complete protection of the organ,or that help to regenerate hepatic ***,it is necessary to identify pharmaceutical alternatives for the treatment of liver diseases,with the aim of these alternatives being more effective and less *** use of some plants and the consumption of different fruits have played basic roles in human health care,and diverse scientific investigations have indicated that,in those plants and fruits so identified,their beneficial effects can be attributed to the presence of chemical compounds that are called *** present review had as its objective the collecting of data based on research conducted into some fruits(grapefruit,cranberries,and grapes)and plants[cactus pear(nopal)and cactus pear fruit,chamomile,silymarin,and spirulina],which are consumed frequently by humans and which have demonstrated hepatoprotective capacity,as well as an analysis of a resin(propolis)and some phytochemicals extracted from fruits,plants,yeasts,and algae,which have been evaluated in different models of hepatotoxicity.

关键词： Hepatoprotection Grapefruit Vaccinium spp Vitis vinifera L Opuntia ficus-indica Spirulina Propolis Glucans Alcoholic liver disease

Antioxidant Capacity and Bioaccessibility of Synergic Mango (cv. Ataulfo) Peel Phenolic Compounds in Edible Coatings Applied to Fresh-Cut Papaya

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Food and nutrition Sciences 2015年第3期6卷 365-373页

作者： Gustavo Rubén Velderrain-Rodríguez Maribel Ovando-martínez Mónica Villegas-Ochoa Jesús Fernando Ayala-Zavala Abraham Wall-Medrano Emilio álvarez-Parrilla Tomás Jesús Madera-Santana Humberto Astiazarán-García Orlando Tortoledo-Ortiz Gustavo adolfo González-Aguilar Coordinación en Tecnología de Alimentos de Origen Vegetal Centro de Investigación en Alimentación y Desarrollo Hermosillo México Instituto de Ciencias Biomédicas Universidad Autónoma de Ciudad Juárez Chihuahua México Departamento de nutrición Humana Coordinación de Nutrición Centro de Investigación en Alimentación y Desarrollo Hermosillo México

Edible coatings (EC) applied to fresh-cut fruits are used to increase their shelf-life and to deliver antioxidant bioactives such as phenolic compounds (PC) that reduce their oxidative damage while enhance their functional value. However, the combination of different PC may have synergetic, additive or antagonic effects on the final antioxidant capacity (AOXC). The aim of this study was to examine the AOXC of binary combinations of selected PC from mango peel and their bioaccessibility from 6% alginate-based EC applied to fresh-cut papaya, under simulated gastrointestinal conditions. Among equimolar (0.1 mM) combinations, gallic + protocatechuic acids (AB) were synergic in radical scavenging activity (RSA) as assayed by DPPH (90% RSA) and FRAP (0.39 mg TE/mL) methods;when assayed in 6% alginate-based EC, their RSA increased (117.85% RSA, 0.88 mg TE/mL). The application of EC + AB to papaya cubes and further in vitro digestion decreased their AOXC probably due to interactions between EC and papaya’s matrix. Therefore, further studies are needed in order to evaluate the effect of combination of phenolic and EC applied in other fruits matrix on antioxidants bioaccessibility.

关键词： Edible Coating Phenolic Acids Antioxidant Capacity Bioaccessibility