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Improved Outcomes Following Hepatocellular Carcinoma(HCC)Diagnosis in Patients Screened for HCC in a Large Academic Liver Center versus Patients Identified in the Community

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Journal of Clinical and Translational Hepatology 2017年第1期5卷 31-34页

作者： Nneoma Okoronkwo Yucai Wang Capecomorin Pitchumoni Baburao koneru Nikolaos Pyrsopoulos Department of Medicine Rutgers New Jersey Medical SchoolNew JerseyUSA Division of Gastroenterology Hepatology and Clinical NutritionSaint Peters University HospitalNew JerseyUSA Department of Surgery Rutgers New Jersey Medical SchoolNew JerseyUSA Division of Gastroenterology and Hepatology Rutgers New Jersey Medical SchoolNew JerseyUSA

Background and Aims:Hepatocellularcarcinoma(HCC)isthe sixth most commonly occurring cancer *** and adherence to HCC surveillance guidelines has been associated with earlier *** sought to evaluate characteristics and outcomes following HCC diagnosis in patients screened for HCC in a large academic liver center versus patients diagnosed and referred from the ***:We reviewed the records of patients diagnosed with HCC in the liver center of an academic institution from January 1999 till December *** were classified into two groups:patients followed in our hepatology clinic and patients with HCC recently referred to our *** analysis was performed using chi-squared test and multivariate analysis was performed using SPSS ***:The records of 410 patients were reviewed,and included 77.3%of patients referred from the community and 22.7%of patients followed in our *** the clinic group,75.6%were identified with one nodule at initial diagnosis,compared to 65.6%in the referral *** in the referral group were more likely to present with tumors≥5 cm at diagnosis,with 28.7%compared to 5.4%in the clinic group(P<0.0001).Patients referred from the community were also less likely to undergo transplant,with 32.2%as compared to 48.4%of the clinic group(P<0.004).Conclusion:Patients with chronic liver disease managed in an academic liver center present in the early stage of HCC diagnosis and are more likely to meet the Milan criteria and undergo *** referral to a specialized transplant center,if feasible,where a multidisciplinary approach is utilized might be essential in the management of chronic liver disease.

关键词： Hepatocellular carcinoma Liver transplant Tumor

Rectification of RF Fields in Load Dependent Coupled Systems: Application to Non-Invasive Electroceuticals

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Journal of Biomedical Science and Engineering 2016年第2期9卷 112-121页

作者： Sree N. koneru Charles R. Westgate Kenneth J. McLeod Clinical Science and Engineering Research Laboratory Binghamton University Binghamton NY USA Department of Electrical and Computer Engineering Binghamton University Binghamton NY USA

Electroceuticals are medical devices that employ electric signals to alter the activity of specific nerve fibers to achieve therapeutic effects. The rapid growth of RF microelectronics has resulted in the development of very small, portable, and inexpensive shortwave and microwave radio frequency (RF) amplifiers, raising the possibility of utilizing these new RF technologies to develop non-contact electroceutical devices. However, the bio-electromagnetics literature suggests that beyond 10 MHz, RF fields cannot influence biological tissue, beyond simple heating, because effective demodulation mechanisms at these frequencies do not exist in the body. However, RF amplifiers operating at or near saturation have non-linear interactions with complex loads, and if body tissue creates a complex loading condition, the opportunity exists for the coupled system to produce non-linear effects, that is, the equivalent of demodulation may occur. Correspondingly, exposure of tissue to pulsed RF energy could result in the creation of low frequency demodulation components capable of influencing tissue activity. Here, we develop a one-dimen- sional, numerical simulation to investigate the complex loading conditions under which such demodulation could arise. Applying these results in a physical prototype device, we show that up to7.5% demodulation can be obtained for a 40 MHz RF field pulsed at 1 KHz. Implications for this research include the possibility of developing wearable, electromagnetic electroceutical de- vices.

关键词： RF Demodulation in Tissue Non-Linear Coupling Complex Load-Line Electroceuticals Neuromodulation Stochastic Resonance

用PhotoScan扫描并清理的方法给电影人物建模

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艺术教育 2018年第2期 69-71页

作者： Santhosh koneru 无 blur studio动画公司茶树网学院

在本教程中,我将带大家预览为CG电影中人物建模及贴图的过程。我们将涵盖如何只用单个数码相机凭借照片扫描技术扫描演员,以及使用Agisoft PhotoScan软件数据生成数码版本。之后,我们会涉猎如何用ZBrush软件清理扫描,并利用软件提供的... 详细信息

在本教程中,我将带大家预览为CG电影中人物建模及贴图的过程。我们将涵盖如何只用单个数码相机凭借照片扫描技术扫描演员,以及使用Agisoft PhotoScan软件数据生成数码版本。之后,我们会涉猎如何用ZBrush软件清理扫描,并利用软件提供的分层系统在Mudbox中雕刻第三细节。最后,我们将一探怎样用Mudbox中的输出设定输出位移图,以及如何用V-Ray使它们处于Maya中的低精度网格中。

关键词：技术扫描建模人物电影清理数码相机数据生成 Maya

Rheumatoid Nodule Causing Perforation of Anterior Mitral Leaflet and Severe Mitral Regurgitation: A Rare Case Report

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World Journal of Cardiovascular Diseases 2014年第4期4卷 156-159页

作者： Jayanth koneru Matthew Cholankeril Priyank Shah Fayez Shamoon Hartaj Virk Mahesh Bikkina Seton Hall Cardiology Fellowship Program St. Joseph’s Regional Medical Center Paterson USA Seton Hall Cardiology Fellowship Program St. Michael’s Medical Center Newark USA Seton Hall Internal Medicine Program St. Michael’s Medical Center Newark USA

Rheumatoid arthritis (RA) is a systemic disorder that is chronic in nature and difficult to treat. RA presents in many variants. Here we present an interesting case only seldom described before. Our patient presented to emergency room with acute shortness of breath and was seen to have acute pulmonary edema. Patient later had urgent echocardiography which revealed severe mitral regurgitation from ruptured anterior leaflet. Patient was taken for heart valve replacement and was found to have RA nodule on ruptured leaflet. There are cases involving aortic valve but to our knowledge there are no reports of RA nodule on mitral leaflet.

关键词： Rheumatoid Arthritis Rheumatoid Nodule Heart Failure Mitral Valve Replacement