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Improvised Technique for Analyzing Data and Detecting Terrorist Attack Using Machine Learning Approach Based on Twitter Data

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Journal of Computer and Communications 2020年第7期8卷 50-62页

作者： aditi sarker Partha Chakraborty S. M. Shaheen Sha Mahmuda Khatun Md. Rakib Hasan Kawshik Banerjee Department of Computer Science and Engineering Comilla University Cumilla Bangladesh Department of Computer Science and Engineering Jahangirnagar University Dhaka Bangladesh Department of Information and Communication Technology Comilla University Cumilla Bangladesh Department of Computer Science and Engineering Rajshahi University of Engineering & Technology Rajshahi Bangladesh

Social media are interactive computer mediated technology that facilitates the sharing of information via virtual communities and networks. And Twitter is one of the most popular social media for social interaction and microblogging. This paper introduces an improved system model to analyze twitter data and detect terrorist attack event. In this model, a ternary search is used to find the weights of predefined keywords and the Aho-Corasick algorithm is applied to perform pattern matching and assign the weight which is the main contribution of this paper. Weights are categorized into three categories: Terror attack, Severe Terror Attack and Normal Data and the weights are used as attributes for classification. K-Nearest Neighbor (KNN) and Support Vector Machine (SVM) are two machine learning algorithms used to predict whether a terror attack happened or not. We compare the accuracy with our actual data by using confusion matrix and measure whether our result is right or wrong and the achieved result shows that the proposed model performs better.

关键词： Terrorist Ternary Search Aho-Corasick Automata Confusion Matrix

Rhabdomyolysis-related acute kidney injury in COVID-19:A critical concern

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World Journal of Virology 2025年第1期14卷 127-129页

作者： Md Safiullah sarker Virology Laboratory Infectious Diseases DivisionDhaka 1212Bangladesh

Rhabdomyolysis is a severe condition characterized by the breakdown of muscle tissue leading to the release of intracellular components into the *** condition,when associated with acute kidney injury(AKI),can result in significant morbidity and mortality,particularly in the context of coronavirus disease 2019(COVID-19).This editorial discusses a retrospective study on patients with COVID-19 who developed rhabdomyolysis-related *** study highlights that patients with rhabdomyolysis exhibited higher inflammatory markers,such as Creactive protein,ferritin,and procalcitonin,and experienced worse clinical outcomes compared to those with other causes of *** findings underscore the importance of early recognition and management of rhabdomyolysis in COVID-19 patients to improve prognosis and reduce mortality rates.

关键词： Rhabdomyolysis Acute kidney injury COVID-19 SARS-CoV-2 Creatine kinase Inflammation Prognosis Mortality

A Framework to Assess Possible Sources of Stakeholder Exploitation:A Developing Country Case

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International Journal of Disaster Risk Science 2024年第1期15卷 32-44页

作者： Kamran Shafique Syed Shams Tapan sarker School of Business University of Southern QueenslandSpringfeldQLD 4300Australia Business School University of QueenslandSt LuciaQLD 4072Australia

Solving complex post-disaster reconstruction challenges requires the altruistic involvement of heterogeneous stakeholder ***,small,more organized groups,such as government parastatals,private developers,and contractors often exploit large,unorganized groups,such as affected communities,leaving them more vulnerable to future *** on data collected from a case study in Pakistan,this study proposed a framework to assess,anticipate,and mitigate the exploitation of vulnerable stakeholders in post-disaster reconstruction *** framework draws on influential management theories and utilizes reciprocal relationships between stakeholder attributes(power,legitimacy,and urgency),participation,and *** study also argued for non-binary treatment of stakeholder *** framework will allow practitioners to address issues around the exploitation of stakeholder interests in future post-disaster reconstruction projects.

关键词： Collective action Pakistan Post-disaster reconstruction-Stakeholder participation Stakeholder exploitation

Strategies for translating proteomics discoveries into drug discovery for dementia

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Neural Regeneration Research 2024年第1期19卷 132-139页

作者： aditi Halder Eleanor Drummond School of Medical Sciences and Brain&Mind Center University of SydneyNSWSydneyAustralia Department of Aged Care Prince of Wales HospitalSydneyNSWAustralia

Tauopathies,diseases characterized by neuropathological aggregates of tau including Alzheimer's disease and subtypes of fro ntotemporal dementia,make up the vast majority of dementia *** there have been recent developments in tauopathy biomarkers and disease-modifying treatments,ongoing progress is required to ensure these are effective,economical,and accessible for the globally ageing *** such,continued identification of new potential drug targets and biomarkers is critical."Big data"studies,such as proteomics,can generate information on thousands of possible new targets for dementia diagnostics and therapeutics,but currently remain underutilized due to the lack of a clear process by which targets are selected for future drug *** this review,we discuss current tauopathy biomarkers and therapeutics,and highlight areas in need of improvement,particularly when addressing the needs of frail,comorbid and cognitively impaired *** highlight biomarkers which have been developed from proteomic data,and outline possible future directions in this *** propose new criteria by which potential targets in proteomics studies can be objectively ranked as favorable for drug development,and demonstrate its application to our group's recent tau interactome dataset as an example.

关键词： Alzheimer's disease biomarkers drug development drug discovery druggability frontotemporal dementia interactome proteomics tau tauopathies therapeutics

Therapeutic resistance in pancreatic ductal adenocarcinoma: Current challenges and future opportunities

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World Journal of Gastroenterology 2021年第39期27卷 6527-6550页

作者： aditi Jain Vikas Bhardwaj The Jefferson Pancreas Biliary and Related Cancer CenterDepartment of SurgerySidney Kimmel Cancer CenterThomas Jefferson UniversityPhiladelphiaPA 19107United States Department of Pharmaceutical Sciences Jefferson College of PharmacyThomas Jefferson UniversityPhiladelphiaPA 19107United States

Pancreatic ductal adenocarcinoma(PDAC)is the third leading cause of cancerrelated deaths in the United *** chemotherapeutic regimens such as gemcitabine+nab-paclitaxel and FOLFIRINOX(FOLinic acid,5-Fluroruracil,IRINotecan,and Oxaliplatin)significantly improve patient survival,the prevalence of therapy resistance remains a major roadblock in the success of these *** review discusses the molecular mechanisms that play a crucial role in PDAC therapy resistance and how a better understanding of these mechanisms has shaped clinical trials for pancreatic cancer ***,we have discussed the metabolic alterations and DNA repair mechanisms observed in PDAC and current approaches in targeting these *** discussion also includes the lessons learned following the failure of immunotherapy in PDAC and current approaches underway to improve tumor’s immunological response.

关键词： Pancreatic cancer Metabolism DNA repair Therapy-resistance Immunotherapy

Modeling and Analysis of PV Configurations to Extract Maximum Power Under Partial Shading Conditions

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CSEE Journal of Power and Energy Systems 2022年第6期8卷 1670-1683页

作者： aditi Atul Desai Suresh Mikkili Department of EEE National Institute of Technology GoaGoa 403401India

Photovoltaics(PV)are widely used as renewable energy sources for standalone and grid connected PV *** these PV systems face major reduction in output power and efficiency due to Partial Shading Conditions(PSCs).This research paper focuses on the different choices of optimum PV Configuration under a given shading pattern to extract maximum power by mitigating mismatching *** PV configurations,such as Series(S),Series Parallel(SP),Total Cross Tied(TCT),Bridge Linked(BL),Honey Comb(HC)and Alternate Total Cross Tied–Bridge Linked(A-TCT-BL)are modeled and analyzed under *** shading patterns,such as center,diagonal,corner,L-shaped,short and narrow,short and wide,long and narrow,long and wide and random,are considered to study the behavior of a 6×6 array form of a PV *** performances are compared based on open circuit voltage,short circuit current,global maximum power point(GMPP),maximum voltage,maximum current,shading loss,fill factor,mismatching loss and efficiency.A novel Hybrid Configuration called A-TCT-BL PV Configuration is proposed to generate maximum power under PSCs and to minimize the number of cross ties and wiring *** Configuration is an integration of TCT and BL PV Configuration and the simulation results prove the capability of this proposed PV Configuration to generate maximum power,fill factor,efficiency and minimum mismatching loss compared to S,SP,BL and HC PV Configurations under a majority of the PSCs investigated.A Canadian Solar CS5P-200M PV module is considered for simulation and is simulated using Matlab/Simulink software.

关键词： Alternate Total Cross Tied-Bridge Linked(A-TCT-BL)PV configuration mismatching loss partial shading conditions(PSCs) PV configurations

Molecularly targeted therapy for advanced hepatocellular carcinoma-a drug development crisis?

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World Journal of Gastrointestinal Oncology 2016年第2期8卷 173-185页

作者： Kiruthikah Thillai Paul Ross Debashis sarker department of medical oncology guy’s and st thomas nhs trustLondon SE1 9RTUnited Kingdom division of cancer studies king’s college londonguy’s hospitalLondon SE1 9RTUnited Kingdom institute of liver studies king’s college hospital nhs trustLondon SE5 9RSUnited Kingdom

Hepatocellular carcinoma is the fastest growing cause of cancer related death globally. Sorafenib,a multitargeted kinase inhibitor,is the only drug proven to improve outcomes in patients with advanced disease offering modest survival benefit. Although comprehensive genomic mapping has improved understanding of the genetic aberrations in hepatocellular cancer(HCC),this knowledge has not yet impacted clinical care. The last few years have seen the failure of several first and second line phase Ⅲ clinical trials of novel molecularly targeted therapies,warranting a change in the way new therapies are investigated in HCC. Potential reasons for these failures include clinical and molecular heterogeneity,trial design and a lack of biomarkers. This review discusses the current crisis in HCC drug development and how we should learn from recent trial failures to develop a more effective personalised treatment paradigm for patients with HCC.

关键词： Hepatocellular carcinoma Molecular targets Genomics Sorafenib Tyrosine kinase inhibitors

Understanding gaseous reduction in swine manure resulting from nanoparticle treatments under anaerobic storage conditions

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Journal of Environmental Sciences 2019年第8期31卷 179-191页

作者： Niloy Chandra sarker Md Borhan Ann-Marie Fortuna Shafiqur Rahman Agricultural and Biosystems Engineering Department North Dakota State University USDA-ARS Grazinglands Research Laboratory

Manure is an impending source of carbon(C), sulfur(S) and water(H_2 O). Consequently,microbial populations utilize these constituents to produce methane(CH4), carbon dioxide(CO_2), greenhouse gases(GHGs), and hydrogen sulfide(H_2 S). Application of nanoparticles(NPs) to stored manure is an emerging GHG mitigation technique. In this study, two NPs: nano zinc oxide(nZnO) and nano silver(nAg) were tested in swine manure stored under anaerobic conditions to determine their effectiveness in mitigating gaseous emissions and total gas production. The biological sources of gas production, i.e., microbial populations were characterized via Quantitative Polymerase Chain Reaction(qPCR) analysis. Additionally, pH, redox, and VFAs were determined using standard methods. Each treatment of the experiment was replicated three times and NPs were applied at a dose of 3 g/L of manure. Also, headspace gas from all treatment replicates were analyzed for CH_4 and CO_2 gas concentrations using an SRI-8610 Gas Chromatograph and H_2 S concentrations were measured using a Jerome 631 X meter. Nanoparticles tested in this study reduced the cumulative gas volume by 16%–79% compared to the control. Among the NPs tested, only nZnO consistently reduced GHG concentrations by 37%–97%. Reductions in H_2 S concentrations ranged from 87% to97%. Gaseous reductions were likely due to decreases in the activity and numbers of specific gas producing methanogenic archaea and sulfate reducing bacterial(SRB)species.

关键词： Swine manure Nanoparticles Greenhouse gas Methanogen Sulfate reducing bacteria(SRB)

De-twinning and Texture Change in an Extruded AM30 Magnesium Alloy during Compression along Normal Direction

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Journal of Materials Science & Technology 2015年第3期31卷 264-268页

作者： D.sarker J.Friedman D.L.Chen Department of Mechanical and Industrial Engineering Ryerson University

Twinning and de-twinning are the salient deformation mechanisms in hexagonal close-packed(hcp)metals. The aim of this study was to examine and quantify the de-twinning process involving a reversible motion of twin boundaries in an extruded AM30 magnesium alloy after re-compression along the normal direction(ND) of pre-compressed samples along the extrusion direction(ED). {1012} extension twins were first introduced at a compressive strain of 3.7% along the ED. The subsequent compressive deformation along the ND induced a gradual shrinkage of twins with increasing cumulative true strain,and the complete de-twinning occurred at a strain of ~7.7%. The twin width decreased linearly with increasing true strain. Texture measurements verified the rotation of c-axes of hcp unit cells towards the anti-compression direction due to {1012} extension twinning after compression along the ED, and a gradual return of c-axes to the initial orientation due to twin shrinking or de-twinning during the following compression along the ND. The {1012} twinning corresponded to the formation of new texture components C{1210} and D{0110} and a decrease in the initial texture components A{0001} and B{0001}, while the twin shrinking or de-twinning was characterized by a gradual vanishing of components C{1210} and D{0110} and an increase in the components A{0001} and B{0001}.

关键词： Magnesium alloy Compressive deformation Twinning D