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Comparison of brimonidine-timolol and dorzolamidetimolol in the management of intraocular pressure increase after phacoemulsification

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International Journal of Ophthalmology(English edition) 2015年第5期8卷 945-949页

作者： adem Turk Osman Melih Ceylan Gokcen Gokce Mehmet Borazan Mehmet Kola Department of Ophthalmology Faculty of MedicineKaradeniz Technical University Department of Ophthalmology Medical Park Hospital Department of Ophthalmology Kayseri Military Hospital Department of Ophthalmology Faculty of MedicineMevlana University

AIM: To compare the effectiveness of brimonidine/timolol fixed combination(BTFC) and dorzolamide/timolol fixed combination(DTFC) in the management of short-term intraocular pressure(IOP) increase after phacoemulsification surgery.·METHODS: Eighty eyes of 80 patients undergoing phacoemulsification and intraocular lens(IOL)implantation were randomly assigned into three *** 1 consisted of 28 eyes and represented the control group. Group 2 consisted of 25 eyes undergoing phacoemulsification surgery and BTFC was instilled at the end of surgery. Group 3 consisted of 27 eyes undergoing phacoemulsification surgery and DTFC was instilled at the end of surgery. IOP was measured preoperatively and 6, 24 h and 1wk postoperatively.·RESULTS: There was no statistically significant difference in preoperative baseline IOP among the three groups(P =0.84). However, IOP was significantly lower in groups 2 and 3 compared to the control group(P 25 mm Hg at 6h after surgery(P =0.008). However, IOP decreased and was >25 mm Hg in only one eye in each group at24 h after surgery.·CONCLUSION: BTFC and DTFC have similar effects in reducing increases in IOP after phacoemulsificationsurgery and can both be recommended for preventing IOP spikes after such surgery.

关键词： cataract brimonidine dorzolamide timolol intraocular pressure phacoemulsification postoperative complication

Energy potential assessment and techno-economic analysis of micro hydro-photovoltaic hybrid system in Goda Warke village,Ethiopia

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Clean Energy 2024年第1期8卷 237-260页

作者： Ephrem Assefa Feyissa Getachew Shunki Tibba Tarekegn Limore Binchebo Endeshaw Alemu Bekele adem Tibesso Kole Department of Mechanical Engineering Bule Hora UniversityBule HoraEthiopia Agro Technical and Technology College Menschen fuer Menschen FoundationHararEthiopia Faculty of Mechanical Engineering Jimma Institute of TechnologyJimmaEthiopia Department of Thermal Technology Silesian University of TechnologyGliwicePoland Jimma Agricultural Engineering Research Center JimmaOromia Agricultural Research InstituteEthiopia

Rural Ethiopia has significant untapped potential for hydro and solar energy generation ***,challenges arise from seasonal variations and unfavourable topographic positions of flowing rivers,hindering the efficient exploitation of these *** the country’s abundance in hydro and solar energy resources,>75%of the population still lack access to electricity from the national *** work deals with energy resource potential assessment and techno-economic analysis of micro hydro-photovol-taic(PV)hybrid systems,considered in the case study of Goda Warke village,located in the Yaya Gulele district.A novel framework is proposed that utilizes the Natural Resource Soil Conservation Service curve number method to assess the energy potential of micro-hydro energy in ungauged basins,specifically at the exit point of the Girar River basin *** average monthly flow rate in the basin is 0.975 m3/s,while the area exhibits a solar radiation potential of 5.39 kWh/m^(2)/*** policy promotes expanding ac-cess to modern energy sources and utilization of indigenous energy *** results indicate that the hydro/PV/diesel generator(DG)/battery and hydro/PV/battery systems are the most optimal choices based on net present cost,with the inclusion of a DG for economic ***-hydro energy covers most of the electric load in the area,achieving a capacity factor of 47.5%.The cost of energy and net present cost were found to be sensitive to variables such as the price of diesel fuel,pipe head loss,and the growth of the village *** optimized system demonstrated a hydro energy potential of 1405.37 MWh/year and a PV energy output of 274.04 MWh/year,resulting in a levelized cost of energy of 0.0057 and 0.049$/kWh for the hydro and PV components,respectively.

关键词： energy potential hybrid micro hydro-photovoltaic Natural Resource Soil Conservation Service curve number sensitivity variable

Inappropriate use of digoxin in patients presenting with digoxin toxicity

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Journal of Geriatric Cardiology 2015年第2期12卷 143-146页

作者： Mustafa adem Tatlisu Kazim Serhan Ozcan Baris Gungor Ahmet Zengin Mehmet Baran Karatas Zekeriya Nurkalem Department of Cardiology Sivas Numune State Hospital Rahmi Crunay Street Sivas 58000 Turkey Department of Cardiology Kocaeli Derince Education and Research Hospital ibni Sina Street Kocaeli 41900 Turkey Department of Cardiology Dr.Siyami Ersek Cardiovascular Surgery Education and Research Hospital Tlbbiye street lstanbul 34668 Turkey Department of Cardiology Istanbul Medipol University Kosuyolu Istanbul 34718 Turkey

Background Digoxin remains widely used today despite its narrow therapeutic index and toxicity. The objective of this study was to investigate the percentage of inappropriate use of digoxin and long-term outcomes of elderly patients hospitalized for digoxin toxicity. Methods The study included 99 consecutive patients hospitalized for digoxin toxicity. The other study criteria for the inappropriate use of digoxin was regarded if participants having depressed left ventricular systolic function （ejection fraction 〈 45%） who were not on optimal medical therapy including beta-blocker and angiotensin-converting-enzyme inhibitor therapy or if participants having permanent AF who were not on optimal beta-blocker therapy. Results Appropriate digoxin usage was confirmed in 33 of patients in spite of its narrow therapeutic index. A total of 16 of 99 patients died, with a mean follow-up time of 22.1 ± 10.3 months. Conclusions Contrary to popular belief, the rate of inappropriate digoxin usage remains high. On account of its narrow therapeutic index and toxicity, digoxin should be used more carefully according to the current evidence and guidelines.

关键词： Digoxin Ejection fraction Indications Toxicity

Effects of phacoemulsification surgery on ocular hemodynamics

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International Journal of Ophthalmology(English edition) 2013年第4期6卷 537-541页

作者： adem Turk Suleyman Mollamehmetoglu Halil Ibrahim Imamoglu Mehmet Kola Hidayet Erdol Nurettin Akyol Department of Ophthalmology School of MedicineKaradeniz Technical University

AIM:To evaluate the possible effects of phacoemulsification cataract surgery on ocular hemodynamics.·METHODS:In this prospective study,intraocular pressure(IOP),pulsatile ocular blood flow(POBF),and ocular pulse amplitude(OPA) were measured pre-operatively(baseline) and at 1 week and 3 weeks postoperation in 52 eyes of 26 patients(mean age 63.15±10.25 years) scheduled for unilateral phacoemulsification cataract surgery with intraocular lens *** all of the eyes,a blood flow analyzer(Paradigm DICON;Paradigm Medical Industries Inc.;USA) was used to obtain measurements of IOP,POBF,and *** data obtained from operated eyes were compared statistically to untreated fellow phakic eyes of the patients.·RESULTS:For operated eyes,the mean baseline IOP,POBF,and OPA values were 15.9±4.64mmHg,17.41±4.84μL/s,and 2.91 ±1.12mmHg,*** IOP,POBF,and OPA values were 17.19 ±4.34mmHg,17.56 ±6.46μL/s,and3.12 ±1.1mmHg,respectively,in the nonoperated control *** significant differences from baseline measurements were not observed 1 week and 3 weeks postoperation for the operated or nonoperated *** were also no statistically significant differences in any measurements between the operated and nonoperated eyes in all the examination periods(P >0.05for all).·CONCLUSION:Uncomplicated phacoemulsification surgery does not affect ocular hemodynamics in normotensive eyes with cataracts.

关键词： cataract cataract extraction intraocular pressure phacoemulsification regional blood flow

Intestinal obstruction due to giant liver cyst:A case report

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World Journal of Clinical Cases 2023年第26期11卷 6246-6251页

作者： adem Küçük Shukri Said Mohamed Abdishakur Mohamed Abdi Abdullahi Yusuf Ali Düzce University Faculty of Medicine Pediatric Surgery ClinicDüzce 81110MerkezTurkey Department of Pediatric Surgery Somali Mogadishu Training and Research HospitalMogadishu 0000000Somalia

BACKGROUND Congenital hepatic cysts are relatively rare but are now diagnosed earlier and more frequently with a routine prenatal *** liver cysts are divided into simple and solitary intrahepatic biliary cysts,depending on the biliary *** some solitary liver cysts are symptomatic in childhood,even in newborns,they are often found incidentally in *** SUMMARY A 3-mo-old female infant was admitted to Mogadishu Somali Training and Research Hospital with recurrent vomiting,respiratory problems,and abdominal bloating *** examination,the abdomen was greatly distended and extremely *** had repeated vomiting for 3 d,no stool output,and decreased *** abdominal ultrasonography detected a solitary cystic lesion measuring 10 cm×10 cm×14 cm,extending from the liver or right kidney to the *** the magnetic resonance imaging examination of the patient,a solitary cystic structure of 10 cm×10 cm×14 cm in the right abdomen was observed,extending to the pelvis and possibly originating from the *** patient was operated via fenestration after her fluid and electrolytes *** nutrition was initiated on the 2nd postoperative day,and the drain was removed on the 5th postoperative *** patient visited the outpatient clinic control 1 mo later with no clinical *** Congenital liver cysts are usually followed without *** rarely reach gigantic dimensions and may cause respiratory distress,intestinal obstruction and recurrent *** can provide quite successful outcomes in the treatment of giant sized simple liver cysts.

关键词： Congenital liver cyst Simple liver cyst Fenestration Pain Intestinal obstruction Case report

Gastrointestinal bezoars: A retrospective analysis of 34 cases

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World Journal of Gastroenterology 2005年第12期11卷 1813-1817页

作者： Kenan Erzurumlu Zafer Malazgirt Ahmet Bektas adem Dervisoglu Cafer Polat Gokhan Senyurek Ibrahim Yetim Kayhan Ozkan Department of Surgery

AIM: Bezoars (BZ) are the most common foreign bodies of gastrointestinal tract. Clinical manifestations vary depending on the location of BZ from no symptoms to acute abdominal syndrome. When located in small bowel, they frequently cause small bowel obstruction (SBO). We aimed to present our experience by reviewing ***: Thirty-four patients with gastrointestinal BZ were presented. The data were collected from hospital records and analyzed retrospectively. Morbidity and mortality rates were statistically analyzed between the subgroups according to SBO and endoscopic or surgical treatment ***: The 34 patients had phytobezoars (PBZ). Two patients with mental retardation and trichotillomania had trichobezoars (TBZ). More than half of them (55.88%) had previous gastric surgery. Also most of them had small bowel bezoars resulting in obstruction. Surgical and endoscopic morbidity rates were 32.14% and 14.28% *** total morbidity rate of this study was 29.41%. Four patients in surgically treated group died. There was no death in endoscopically treated group. The total and surgical mortality rates were 11.76% and 14.28% respectively. The differences in morbidity and mortality rates between the subgroups were not statistically ***: BZ are commonly seen in stomach and small intestine. SBO is the most common *** uncomplicated, endoscopic or surgical removal can be applied easily.

关键词： Bezoars Phytobezoar Trichobezoar

Preparation and characterization of octenyl succinic anhydride nano starch from tiger nut meals

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Food Quality and Safety 2023年第3期7卷 503-515页

作者：王舰张瑞黄镇宇蔡铭楼文雨王龑 adem Gharsallaoui Hynek Roubik 杨开孙培龙 College of Food Science and Engineering Key Laboratory of Food Macromolecular Resources Processing Technology ResearchZhejiang University of TechnologyHangzhouChina CNRS LAGEPP UMR 5007Univ.LyonUniversitéClaude Bernard Lyon 1VilleurbanneLyonFrance Department of Sustainable Technologies Faculty of Tropical AgriSciencesCzech University of Life Sciences PraguePragueCzech Republic

Tiger nut(Cyperus esculentus L.)is an ideal raw material for oil extraction,but starch-rich tiger nut meal,a by-product of oil extraction,has not been fully *** this,starch was isolated from tiger nut meal,and then starch nanoparticles were prepared by gelatinization,ultrasonication and nanoprecipitation under different *** preparation parameters were optimized by measuring the particle size with dynamic light scattering,and the physicochemical properties of native starch and nano starch were *** results showed that,compared to native starch,starch nanoparticle(nano starch)has a higher amylose content(39.05%),solubility(56.13%),and swelling power(58.01%).Furthermore,native starch and nano starch were esterified with octenyl succinic anhydride(OSA),respectively,conferring amphiphilic *** effects of OSA modification on the resistant starch content,thermal properties,and microstructure of starches were *** resistant starch content of tiger nut native starch increased by 10.81%after OSA modification,while the resistant starch content of OSA nano starch increased to 37.76%.Compared to native starch,the gelatinization temperature of OSA nano starch decreased by 2.7℃ and nano starch decreased by 5.68℃.OSA modified nano starch showed a unique microstructure,such as a slender fiber structure and a regular oblate *** hydrophobic OSA groups aggregated to form hydrophobic cavities with a hydrophilic surface in the aqueous *** findings presented in this investigation provide a better understanding of the design and development of OSA nano starch and provide valuable guidance to further enhance the added value of tiger nuts and future applications in the food industry.

关键词： tiger nut starch ultrasonication nanoprecipitation modification OSA nano starch physicochemical properties

Prevalence of smear positive pulmonary tuberculosis in Gondar prisoners,North West Ethiopia

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Asian Pacific Journal of Tropical Medicine 2015年第2期8卷 127-131页

作者： Zelalem Addis Emebet adem Abebe Alemu Wubet Birhan Biniam Mathewos Belaynesh Tachebele Yegnasew Takele School of Biomedical and Laboratory Science College of Medicine and Health ScienceUniversity of GondarGondarEthiopia Leishmania Research and Treatment Center College of Medicine and Health SciencesUniversity of GondarGondarEthiopia University of Gondar Hospital Service Laboratory College of Medicine and Health SciencesUniversity of GondarGondarEthiopia

Objective:To assess the prevalence and risk factors of smear positive pulmonary tuberculosis among Condar town *** West ***:A cross sectional study was conducted from February to July,2008 in Condar *** with cough duration of more than two weeks were involved in the study by giving three sputum samples and filling the questionnaires prepared for risk factor *** fast staining technique was employed to delect the presence of the Mycobacterium tuberculosis bacilli in the sputum *** was analyzed using SPSS version13 computer software and presented in ***-square test was used to assess associations and a P-value less than 0.05 was taken as ***:A total of 384 prisoners,349 male and 35 females,with a mean age of 33.3 years were involved in the *** prevalence of smear positive pulmonary tuberculosis among those prisoners with cough duration of more than two wecks was 8.59%.Only the length of imprisonment had a significant association(χ~2= 18.82,P-value<0.0001) with the prevalence of ***:This study indicated that tuberculosis among prisoners with cough duration of more then two weeks in Gondar prison is very *** Periodic screening of the prisoners and screening of newly introduced prisoners should be practiced so as to minimise the burden of tuberculosis in prisoners.

关键词： Tuberculosis Smear positive pulmonary tuberculosis Prisoners Gondar Ethiopia

Xanthogranulomatous appendicitis: A comprehensive literature review

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World Journal of Gastrointestinal Surgery 2021年第1期13卷 76-86页

作者： Sami Akbulut Khaled Demyati Cemalettin Koc adem Tuncer Emrah Sahin Mehmet Ozcan Emine Samdanci Department of Surgery and Liver Transplant Institute Inonu University Faculty of MedicineMalatya 44280Turkey Department of Surgery An-Najah National UniversityNablus44839Palestine Department of Pathology Inonu University Faculty of MedicineMalatya 44280Turkey

BACKGROUND Xanthogranulomatous inflammation is characterized histologically by a collection of lipid-laden macrophages admixed with lymphocytes,plasma cells,neutrophils,and often multinucleated giant cells with or without cholesterol *** To review the medical literature on xanthogranulomatous appendicitis(XGA).METHODS We present a patient with XGA and review published articles on XGA accessed via the PubMed,MEDLINE,Google Scholar,and Google *** used were“appendix vermiformis,”“appendectomy,”“acute appendicitis,”and“XGA.”The search included articles published before May 2020,and the publication language was not *** search included letters to the editor,case reports,review articles,original articles,and meeting *** or abstracts containing adequate information about age,sex,clinical presentation,white blood cells,initial diagnosis,surgical approach,histopathological and immunohistochemical features of appendectomy specimens were included in the *** A total of 29 articles involving 38 patients with XGA,were retrospectively ***(52.6%)of the 38 patients,aged 3 to 78 years(median:34;IQR:31)were female,and the remaining 18(47.4%)were ***-five patients were diagnosed with acute appendicitis,ruptured appendicitis,or subacute appendicitis,and the remaining 13 patients underwent surgery for tumoral lesions of the ileocecal ***-two of the patients underwent urgent or semi-urgent surgery,and the remaining 16 patients underwent interval *** Xanthogranulomatous inflammation rarely affects the appendix *** is associated with significant diagnostic and therapeutic dilemmas due to its variable *** is often associated with interval appendectomies,and a significant number of patients require bowel resection due to the common presentation of a tumoral *** is usually identified retrospectively on surgical pathology and has no unique features in preo

关键词： Appendix vermiformis Acute appendicitis Appendectomy Interval appendectomy Xanthogranulomatous inflammation CD68 antibody staining