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The relationships between selected soil properties and caesium-137 identify organic carbon,nitrogen and water soluble phenols as indicators of soil erosion processes in different forest stands

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Journal of Forestry Research 2021年第6期32卷 2589-2598页

作者： Federico Romeo Paolo Porto Carmelo Mallamaci adele Muscolo Department of Agriculture Mediterranea UniversityFeo di Vito89122Reggio CalabriaItaly

In the last few decades,the use of environmental radionuclides,particularly caesium-137(^(137)Cs),represented one of the most valid methods for estimating soil ***,the cost associated with the use of the equipment needed for radiometric analyses is still high and,for this reason,finding more easily measurable indicators can be *** is a strong correlation between^(137)Cs,organic carbon(OC),nitrogen(N)and water soluble phenols(WSP)exists,indicating the latter parameters as possible early indicators of soil *** on the above assumptions,the main purpose of this work is to identify specific soil chemical parameters able to indicate early triggering of soil ***,several soil parameters such as pH,electric conductivity(EC),WSP,OC,N and C/N have been evaluated against^(137)Cs and on a comparative *** addition,since the rate of soil erosion depends on the degree of coverage and canopy structure,two different tree species(Pinus nigra laricio *** Fagus sylvatica L.)have been considered in this contribution in which ten different scenarios of forest management have been *** results show that the reduction in tree cover of managed sites triggers erosion and nutrient loss *** has been observed that the loss of^(137)Cs,compared to the control areas,is closely correlated with those of WSP,OC and *** parameters(WSP,OC and N),more easily assessable,can be a valid tool to understand easily,triggering of erosive phenomena.

关键词： ^(137)Cs Erosion indicators Forest thinning Beech forest Pine forest

Epidemiology, clinical-treatment patterns and outcome in 256 hepatocellular carcinoma cases

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World Journal of Gastroenterology 2013年第21期19卷 3207-3216页

作者： Luigi Fenoglio Cristina Serraino Elisabetta Castagna adele Cardellicchio Fulvio Pomero Maurizio Grosso Carlo Senore Department of Internal Medicine Santa Croce Hospital12100 CuneoPiedmontItaly Department of Diagnostic Radiology Santa Croce Hospital12100 CuneoPiedmontItaly AO Città della Salute e della Scienza CPO Piemonte10123 TurinPiedmontItaly

AIM: To analyze the epidemiology, clinical characteristics, treatment patterns and outcome in hepatocellular carcinoma (HCC) patients. METHODS: We analyzed clinical, pathological and therapeutic data from 256 consecutive patients, examined at S. Croce Hospital in Cuneo-Piedmont, with a diagnosis of HCC between 30th June 2000 and 1st July 2010. We analyzed the hospital imaging database and examined all medical records, including the diagnosis code for HCC (155.0 according to the ICD-9M classification system), both for inpatients and outpatients, and discovered 576 relevant clinical records. After the exclusion of reports relating to multiple admissions for the same patient, we identified 282 HCC patients. Moreover, from this HCC series, we excluded 26 patients: 1 patient because of an alternative final diagnosis, 8 patients because of a lack of complete clinical data in the medical record and 17 patients because they were admitted to different health care facilities, leaving 256 HCC patients. To highlight possible changes in HCC patterns over the ten-year period, we split the population into two five-year groups, according to the diagnosis period: 30 th June 2000-30th June 2005 and 1st July 2005-1st July 2010. Patients underwent a 6-mo follow up. RESULTS: Two hundred and fifty-six HCC patients were included (male/female 182/74; mean age 70 years), 133 in the first period and 123 in the second. Hepatitis C virus (HCV) infection was the most common HCC risk factor (54.1% in the first period, 50.4% in the second;P = 0.63); in the first period, 21.8% of patients were alcoholics and 15.5% were alcoholics in the second period (P > 0.05); the non-viral/non-alcoholic etiology rate was 3.7% in the first period and 20.3% in the second period (P < 0.001). Child class A patients increased significantly in the second period (P < 0.001). Adjusting for age, gender and etiology, there was a significant increase in HCC surveillance during the second period (P = 0.01). Differences bet

关键词： Hepatocellular carcinoma Epidemiology Clinical characteristics Surveillance Survival

Genistein Mitigates the Gastro-Toxic Effects of Bisphenol A in Male Wistar Rats

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Journal of Biosciences and Medicines 2022年第9期10卷 60-78页

作者： Abayomi Oluwatosin Ige Olayinka Oyinkansola Adebayo Bernard Omokheshi adele Anthony Olusoji Odetola Idara Emmanuel Emediong Elsie Olufunke Adewoye Applied and Environmental Physiology Unit Department of Physiology University of Ibadan Ibadan Nigeria Department of Physiology College of Health Sciences Nnamdi Azikwe University Akwa Nigeria

Exposure to Bisphenol A (BPA) worldwide is on the increase. Its toxicities in various tissues expressing estrogen receptors have been reported. However, limited information exists on its effects on the gastric tissue. This study therefore investigated the gastric effects of BPA exposure and the likely ameliorative potential of genistein, a phytoestrogen antioxidant, known to interact with estrogen receptors. Eighty-four male Wistar rats were randomly divided into 6 groups (n = 14) and orally treated for 28 days. Group I-IV received distilled water (0.2 ml), corn oil (3 ml/kg), BPA (50 mg/kg) and genistein (50 mg/kg) respectively. Group V was pre-treated daily with BPA one hour prior to genistein administration while Group VI was pre-treated daily with genistein one hour prior to BPA treatment. Thereafter, blood was collected into heparinized bottles for hematological analysis. Gastric juice was collected for pH and electrolytes determination. Gastric tissue was excised and analyzed for superoxide dismutase (SOD), reduced glutathione (GSH), malondialdehyde, nitric oxide (NO), mucin, parietal and mucous cell counts, and histology. The BPA only treatment group exhibited significant increases (p white blood cell count, neutrophil-lymphocyte ratio, mucin concentration, NO, and malondialdehyde while gastric juice pH, bicarbonate, SOD, and GSH levels were reduced compared to control. The gastric mucosa also showed pathologies consistent with inflammation. Genistein pre-and post-treatment in BPA exposed rats significantly (p < 0.05) ameliorated these effects of BPA. However, some signs of gastric inflammation were still evident in the mucosal samples. Bisphenol A induces gastro-toxicity by increasing gastric acidity, reducing gastric juice bicarbonate level and disrupting prooxidant/antioxidant balance. Genistein pre- and post-treatment ameliorated these gastro-toxic effects of Bisphenol A via gastroprotective, antioxidant and anti-inflammatory mechanisms.

关键词： Bisphenol A Genistein Stomach Gastro-Protection Gastric Impairment

Technology Readiness of a Vertical-Axis Hydro-Kinetic Turbine

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Journal of Power and Energy Engineering 2018年第8期6卷 63-85页

作者： Stefan Runge Thorsten Stoesser Emily Morris Madeleine white Hydro-Environmental Research Centre Cardiff University Cardiff Wales UK

In this paper, the development of a vertical axis hydrokinetic twin turbine for harvesting energy from flowing water in man-made channels is described. The Technology Readiness Level (TRL) assessment procedure, developed by NASA and modified by the US Department of Energy, is followed and it is shown that the hydrokinetic turbine successfully reaches TRL 7, which is a full-scale, similar (prototypical) system demonstrated in a relevant environment. The concept of the twin turbine (TRL 1 - 3) is first validated and tested using a 1:10 scale laboratory model at Cardiff University and efficiencies of up to 75% are achieved (TRL 4 - 5). In order to justify system functionality and performance in a relevant environment as well as up-scalability, a 1:3 scale model of the twin turbine is implemented and tested in a discharge channel of a water treatment plant in Atlanta, thereby achieving TRL6. This paved the way for an application in the form of an array of ten full-scale twin turbine prototypes, including all relevant components such as housing, drive-train, gear-box and generator. Successful deployment and testing in the South Boulder Canal near Denver means that the hydrokinetic twin turbine system reached TRL7.

关键词： Hydro-Turbine Vertical-Axis VAT Micro-Hydro TRL Technology Readiness Level

Single-entity electrochemistry at confined sensing interfaces

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Science China Chemistry 2020年第5期63卷 589-618页

作者： Yi-Lun Ying Jiajun Wang Anna Rose Leach Ying Jiang Rui Gao Cong Xu Martin A.Edwards Andrew D.Pendergast Hang Ren Connor K.Terry Weatherly Wei Wang Paolo Actis Lanqun Mao Henry S.white Yi-Tao Long State Key Laboratory of Analytical Chemistry for Life Science School of Chemistry and Chemical EngineeringNanjing UniversityNanjing 210023China School of Electronic and Electrical Engineering University of LeedsWoodhouse LaneLS29JTLeedsUK Beijing National Laboratory for Molecular Sciences Key Laboratory of Analytical Chemistry for Living BiosystemsInstitute of Chemistrythe Chinese Academy of Sciences(CAS)Beijing 100190China College of Chemistry Beijing Normal UniversityBeijing 100875China University of Chinese Academy of Sciences Beijing 100049China Department of Chemistry University of UtahSalt Lake CityUT 84112United States Department of Chemistry The University of North Carolina at Chapel HillChapel HillNorth Carolina 27599United States Department of Chemistry&Biochemistry Miami UniversityOxfordOH 45056United States

Measurements at the single-entity level provide more precise diagnosis and understanding of basic biological and chemical *** advances in the chemical measurement provide a means for ultra-sensitive *** the single analyte and electrons near the sensing interface can greatly enhance the sensitivity and *** this review,we summarize the recent progress in single-entity electrochemistry of single molecules,single particles,single cells and even brain *** benefits of confining these entities to a compatible size sensing interface are ***,the opportunities and challenges of single entity electrochemistry are addressed.

关键词： single entity electrochemistry confining effect sensors nanopores nanoparticles single cell brain

新西兰苹果品种及砧木育种成就与对中国的启示

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果树学报 2016年第4期33卷 482-491页

作者：张恒涛 BUS Vincent G.M. white Allan G. 阎振立过国南张瑞萍刘珍珍 YAO Jia-long CHAGNE David 中国农业科学院郑州果树研究所郑州450009 新西兰植物与食品研究所新西兰Havelock North 4157 新西兰植物与食品研究所新西兰Auckland 1142 新西兰植物与食品研究所新西兰Palmerston North 4442

20世纪60年代新西兰的Don Mc Kenzie博士从果农***配置的杂交后代中选出了世界级的苹果品种‘嘎拉’。随后,新西兰植物与食品研究所于80年代初期开始了持续专业的苹果育种研究,先后培育出了一系列优良的世界性品种。苹果育种技术也从常... 详细信息

20世纪60年代新西兰的Don Mc Kenzie博士从果农***配置的杂交后代中选出了世界级的苹果品种‘嘎拉’。随后,新西兰植物与食品研究所于80年代初期开始了持续专业的苹果育种研究,先后培育出了一系列优良的世界性品种。苹果育种技术也从常规育种进入了分子育种时代,一跃成为世界苹果育种强国,吸引了世界众多果树科研单位和育种者争相学习其先进技术和科研成果。为了进一步提升中国苹果育种水平,缩小与苹果育种强国的差距,作者系统的介绍了新西兰的苹果品种和砧木选育的发展历程、选育方法,特别是生物技术在新品种选育中的应用,并对比分析目前中国苹果品种及砧木选育的方法,提出中国苹果育种方法的改进建议,希望对中国的苹果育种工作有所启发。

关键词：苹果品种砧木遗传标记基因组选择新西兰中国

含氟达拉滨预处理方案对异基因造血干细胞移植过程中造血重建、移植物抗宿主病及患者生存的影响

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中国组织工程研究与临床康复 2009年第32期13卷 6314-6318页

作者：杨凯陈惠仁何学鹏司英健杜振兰张小妹解放军北京军区总医院造血干细胞移植中心北京市100700

目的:观察接受不同预处理方案改良Bucy(白消安/阿糖胞苷/环磷酰胺)或白消安/氟达拉滨对异基因造血干细胞移植后造血重建,移植物抗宿主病及生存的影响。方法:选择2006-12/2008-06解放军北京军区总医院收治的行异基因造血干细胞移植恶性... 详细信息

目的:观察接受不同预处理方案改良Bucy(白消安/阿糖胞苷/环磷酰胺)或白消安/氟达拉滨对异基因造血干细胞移植后造血重建,移植物抗宿主病及生存的影响。方法:选择2006-12/2008-06解放军北京军区总医院收治的行异基因造血干细胞移植恶性血液病患者27例,按移植预处理方案不同分为两组,10例给予以氟达拉滨+白消安为基础的预处理方案:移植前2～6d氟达拉滨30mg/(m2·d),移植前3～6d白消安3.2mg/(kg·d);17例给予以改良Bucy为基础的预处理方案:移植前4～6d白消安4mg/(kg·d),移植前两三天环磷酰胺60mg/(kg·d)和阿糖胞苷2.0g/(m2·d)。比较两组患者移植后白细胞、血小板重建时间,移植物抗宿主病的发生及其程度,复发与移植相关死亡率。结果:白细胞、血小板重建时间在Bucy组与白消安/氟达拉滨组分别为[(8.45±2.31),(8.96±2.47)d,P=0.957;(13.31±4.80),(15.89±5.21)d,P=0.662]。Bucy组与白消安/氟达拉滨组患者急性移植物抗宿主病发生率分别为[47%(8/17),40%(4/10),P=0.629]。27例患者截至统计时间10例死亡,其中复发死亡4例,移植物抗宿主病死亡3例,感染死亡2例,其他移植合并症死亡1例。Bucy组与白消安/氟达拉滨组1年内总生存率分别为(58.30±19.80)%和(73.00±11.80)%,1年内无病生存率为(48.60±18.70)%和(72.20±12.80)%,白消安/氟达拉滨组总生存率及无病生存率均较Bucy组高,但两组1年内总生存率、无病生存率差异均无显著性意义(P=0.511,0.854)。结论:氟达拉滨应用于移植预处理方案中,可降低异基因造血干细胞移植过程中髓外毒性,但对疗效并无明显影响。

关键词：氟达拉滨异基因造血干细胞移植移植物抗宿主病

内镜自体荧光成像技术将提高Barrett食管早期瘤检测率

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世界核心医学期刊文摘（胃肠病学分册） 2005年第9期1卷 30-31页

作者： Kara M.A. Peters F.P. ten Kate F.J.W. J.J.G.H.M. Bergman 赵天智 Dept. of Gastroenterol. and Hepatol. Academic Medical Center Meibergdreef 9 1105 AZ Amsterdam Netherlands Dr.

Background: The aim of this study was to investigate the feasibility of detecting high-grade dysplasia (HGD) and early cancer (EC) in Barrett’s esophagus (BE) with a prototype video autofluorescence endoscope. Methods: Sixty patients with BE were evaluated with a prototype, high-resolution video-endoscope that has separate charge-coupled devices for white light endoscopy (WLE) and autofluorescence imaging (AFI). Nondysplastic BE appears green on AFI, whereas potentially neoplastic areas appear blue/violet. The BE was first screened with WLE for visible abnormalities and then was examined by AFI to detect additional lesions. Lesions that raised a suspicion of neoplasia and control areas that were normal on AFI were sampled for histopathologic assessment. Finally, random 4-quadrant biopsy specimens were obtained at 2-cm intervals. Results: A diagnosis of HGD/EC was made in 22 patients; one patient had no visible abnormality, and 21 had endoscopically detectable areas with HGD/EC. In 6 of the latter 21 patients, the HGD/EC was detected with AFI alone; in another patient, HGD/EC was detected with AFI and random biopsies. In 14 patients, HGD/EC was detected with both WLE and AFI; in 3 of these 14 patients, additional lesions containing HGD/EC were detected by AFI alone. Conclusions: The results of this study suggest that video AFI may improve the detection of HGD/EC in patients with BE.

关键词： Barrett 自体荧光不典型增生瘤形成早期癌变组织病理学屏幕显示天智高分辨率四象限

入院时中性粒细胞与淋巴细胞比值和血糖水平对急性脑出血患者短期预后不良的预测价值

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中国神经免疫学和神经病学杂志 2019年第4期26卷 275-280页

作者：杨小旺张富山褚小朋杨永新高丽孙昌勇滕兆平江苏省扬州市扬州大学附属江都人民医院神经内科

目的分析急性脑出血患者短期预后不良的相关危险因素,并探讨入院时中性粒细胞与淋巴细胞比值(neutrophil-to-lymphocyte ratio,NLR)和入院即刻血糖水平(admission blood glucose,ABG)对短期预后不良的预测价值。方法收集2017-01-2018-0... 详细信息

目的分析急性脑出血患者短期预后不良的相关危险因素,并探讨入院时中性粒细胞与淋巴细胞比值(neutrophil-to-lymphocyte ratio,NLR)和入院即刻血糖水平(admission blood glucose,ABG)对短期预后不良的预测价值。方法收集2017-01-2018-05期间作者医院收治的急性脑出血患者226例,根据3个月时改良Rankin评分量表(modified Rankin scale,mRS)评分分为预后良好(mRS≤2分)组124例,预后不良(mRS>2分)102例,单因素分析两组患者入院时的临床、影像学及实验室资料,采用二分类Logistic回归分析探讨影响急性脑出血患者短期预后不良的危险因素,采用受试者工作特征(receiver operating characteristic,ROC)曲线评价NLR和ABG对短期预后不良的预测价值。结果 (1)与预后良好组相比,预后不良组患者糖尿病病史、饮酒史比例以及年龄、美国国立卫生研究院卒中量表(National Institute of Health stroke scale,NIHSS)评分均升高,血肿体积大,出血破入脑室比例高,白细胞计数(ABC)、中性粒细胞计数(ANC)、NLR及ABG升高,淋巴细胞计数(ALC)低(均P<0.05)。(2)二分类Logistic回归分析显示患者年龄(OR=1.051,95%CI:1.013~1.090,P<0.01)、血肿体积(OR=1.055,95%CI:1.003~1.110,P<0.05)、NLR(OR=1.389,95%CI:1.124~1.716,P<0.01)、ABG(OR=1.308,95%CI:1.074~1.593,P<0.05)及NIHSS评分(OR=1.151,95%CI:1.065~1.243,P<0.01)升高为急性脑出血患者短期预后不良的独立危险因素。(3)ROC曲线分析表明,NLR和ABG的ROC曲线下面积分别为0.767(95%CI:0.705~0.829,P<0.01)、0.678(95%CI:0.609~0.747,P<0.05)。结论入院时年龄、血肿体积、NIHSS评分、NLR及ABG升高是急性脑出血患者短期预后不良的独立危险因素,NLR和ABG对急性脑出血患者短期预后不良有一定的预测价值。

关键词：脑出血预后中性粒细胞淋巴细胞比值血糖危险因素预测价值