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Maternal & child health nursing : care of the childbearing & childrearing family / adele Pillitteri. 5th ed.

1999年

作者： adele Pillitteri.

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Pro and anti-inflammatory diets as strong epigenetic factors in inflammatory bowel disease

2007年

作者： adele Pillitteri.

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World Journal of Gastroenterology 2024年第27期30卷 3284-3289页

作者： adele Rostami Kristen White Kamran Rostami Digestive Health Clinic Palmerston North 4410New Zealand Digestive Health Clinic&Kōtare Wellness Ltd Palmerston North 4410New Zealand Department of Gastroenterology Palmerston North HospitalPalmerston North 4442New Zealand

Inflammatory bowel disease(IBD)is the consequence of a complex interplay between environmental factors,like dietary habits,that alter intestinal microbiota in response to luminal antigens in genetically susceptible *** represents an auspicious area for the discovery of how environmental factors influence the pathogenesis of inflammation,prognosis,and response to ***,it relates to gene expression control in response to environmental *** increasing number of patients with IBD globally is indicative of the negative effects of a food supply rich in trans and saturated fats,refined su-gars,starches and additives,as well as other environmental factors like seden-tarism and excess bodyweight,influencing the promotion of gene expression and increasing DNA hypomethylation in *** many genetic variants are now associated with Crohn's disease(CD),new therapeutic strategies targeting modi-fiable environmental triggers,such as the implementation of an anti-inflammatory diet that involves the removal of potential food antigens,are of growing interest in the current ***,as a strong epigenetic factor in the pathogenesis of inflammatory disorders like IBD,provides novel insights into the pathophysio-logy of intestinal and extraintestinal inflammatory disorders.

关键词： Inflammatory bowel disease Epigenetic Anti-inflammatory diet Immunogenetics Microbiome Polymeric diet Elemental diet

Garcinia Kola and Kolaviron Attenuates Bisphenol A-Induced Memory Impairment and Hippocampal Neuroinflammation in Male Wistar Rats

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Journal of Biosciences and Medicines 2024年第2期12卷 111-130页

作者： Nazizi Adamu Kayinu Bernard Omokheshi adele Abayomi Oluwatosin Ige Applied and Environmental Physiology Unit Department of Physiology University of Ibadan Ibadan Nigeria Department of Physical and Health Education College of Education Akwanga Nigeria

Bisphenol A (BPA), a toxicant which can leach into food from plastic containers, is reported to induce neurotoxicity among others via oxidative mechanisms. However, antioxidant compounds have been suggested to mitigate BPA-induced toxicities. Garcinia kola (GK) and its bioactive compound, kolaviron, are well-established natural antioxidants, which can exert protective effects against BPA-induced toxicities. This study was designed to investigate the likely mitigating effect of GK and kolaviron on BPA-induced memory impairment and hippocampal neuroinflammation in male Wistar rats. Thirty-five rats were equally grouped and treated as follows: I and II received distilled water and corn oil, respectively at 0.2 mL, while III - VII received BPA (50 mg/kg), BPA + GK (200 mg/kg), BPA + kolaviron (200 mg/kg), GK and kolaviron, respectively for 28 days p.o. Thereafter, behavioral studies were done using the Novel Object Recognition and Y maze tests. Subsequently under anaesthesia, the hippocampus in each animal was dissected out, homogenized and analysed for malondialdehyde, superoxide dismutase, catalase, reduced glutathione, glutathione transferase, nitrites, interleukin-6, tumour necrosis factor-α, acetylcholinesterase, glutamate acid decarboxylase, and arginase activity. Data were analyzed by ANOVA and Tukey Post-hoc test at p p Garcinia kola and Kolaviron mitigate bisphenol A-induced memory impairment and neuroinflammation via antioxidant potentiation and neurotransmitter balance.

关键词： Bisphenol A Memory Impairment Neuroinflammation Neuroprotection Garcinia Kola Kolaviron Antioxidant

An Automated,Highly Selective Reaction Monitoring Instrument Using Molecular Rotational Resonance Spectroscopy

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Precision Chemistry 2024年第2期2卷 57-62页

作者： Ann adele Byars Khushi R.Kompally Emily Mechnick Reilly E.Sonstrom Alexander Mikhonin Justin L.Neill Ruth Boetzel James MacGregor Courtney Talicska Jian Li Yizhou Liu BrightSpec Inc.CharlottesvilleVirginia 22903United States Pfizer R&D UK Limited Sandwich CT139NJUnited Kingdom Analytical Research and Development Pfizer Research and DevelopmentGrotonConnecticut 06340United States

Online monitoring of chemical reactions by using analytical chemistry tools is a powerful way to maximize control over these *** this paper,we demonstrate the use of molecular rotational resonance,an emerging and extraordinarily selective spectroscopic technique,to perform automated reaction monitoring *** interface using a six-port valve with a calibrated sample loop,coupled to a temperature controlled inlet for analyte volatilization,was developed and *** reactions were chosen for initial characterization:an amine-aldehyde condensation reaction to form an imine product and an isotopic exchange reaction of aβ-ketoester with keto-enol *** spectrometer was able to provide kinetic information about the reaction and determine reaction *** the future,this system can be extended to detect and quantify impurities and characterize reaction selectivity,in addition to the reaction progress.

关键词： molecular rotational resonance spectroscopy reaction monitoring reaction kinetics isotopes process analytical technology

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空中英语教室（高级版．彭蒙惠英语） 2024年第1期 24-26,45,46页

作者： adele Peters Heather Carlson Kehren 不详

18钢拱桥:专门供熊、驼鹿及其他野生动物使用的桥如果你在加拿大卡尔加里市以西的加拿大横贯公路上开车——这条公路穿越落基山脉、两侧林立着望不尽的森林——你会看到一座建设中的巨大钢拱桥。它即将是该地区最新的野生动物通道,帮助... 详细信息

18钢拱桥:专门供熊、驼鹿及其他野生动物使用的桥如果你在加拿大卡尔加里市以西的加拿大横贯公路上开车——这条公路穿越落基山脉、两侧林立着望不尽的森林——你会看到一座建设中的巨大钢拱桥。它即将是该地区最新的野生动物通道,帮助熊、驼鹿、偶尔出现的大角羚羊和其他动物穿越四排车道的高速车流。

关键词：钢拱桥公路穿越野生动物通道加拿大车流车道

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空中英语教室（高级版．彭蒙惠英语） 2024年第8期 16-18,42,43页

作者： Lebawit Lily Girma adele Peters 不详

酒店房价上涨最快的城市根据一份最新报告指出,从波士顿到孟买,全球各大城市的酒店房价预计将以两位数的百分比升,即使曾经预测酒店房价已经涨到最高点美国运通全球商务旅行集团发布的《2024年酒店监测报告》显示,布宜诺斯艾利斯摘得今... 详细信息

酒店房价上涨最快的城市根据一份最新报告指出,从波士顿到孟买,全球各大城市的酒店房价预计将以两位数的百分比升,即使曾经预测酒店房价已经涨到最高点美国运通全球商务旅行集团发布的《2024年酒店监测报告》显示,布宜诺斯艾利斯摘得今年桂冠,年涨幅达17%。这份报告研究了全球80多个城市的酒店价格波动情况,预测标准包括当前的挂牌价格、更广泛的宏观经济趋势、酒店开发渠道和历史数据。

关键词：商务旅行房价上涨美国运通监测报告大城市新闻集锦宏观经济历史数据

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空中英语教室（高级版．彭蒙惠英语） 2024年第5期 20-22,43,44页

作者： Nate Berg Michael Grothaus adele Peters 不详

底特律的未来街道将会为行驶于其上的车辆充电未来的电动车充电。有可能藏在底特律一条街道的沥青之下。这是美国首度将电动车充电技术内嵌于公共道路中。这条电动车充电道路建于底特律市中心外一段四分之一英里(约402.34米)长的街道中... 详细信息

底特律的未来街道将会为行驶于其上的车辆充电未来的电动车充电。有可能藏在底特律一条街道的沥青之下。这是美国首度将电动车充电技术内嵌于公共道路中。这条电动车充电道路建于底特律市中心外一段四分之一英里(约402.34米)长的街道中,是对一项被称为磁共振感应的新兴技术进行测试。它是利用内嵌于街道里的铜线圈将电力从电网传送给路面上方经过的电动车。车载接收器会吸收那些电力——通常只有少量而为电池持续充电。

关键词：公共道路电动车充电底特律新兴技术磁共振接收器电力

Diagnosis of CAH in a Sub Saharan Country: Visible Part of Iceberg

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Open Journal of Pediatrics 2024年第2期14卷 227-233页

作者： Suzanne Sap Ritha Mbono Hélène Kamo Jocelyn Tony Charlotte Eposse Jeannette Epée Isabelle Mekone adele Bodieu Gaelle Ntsoli Paul Olivier Koki Mother and Child Center of the Chantal Biya Foundation University of Yaoundé I Yaoundé Cameroon Laquintinie Hospital University of Douala Douala Cameroon Genral Hospital of Garoua University of Garoua Garoua Cameroon Human Reproductive Center and Research on Fertility of Yaoundé University of Yaoundé I Yaoundé Cameroon Yaounde General Hospital University of Yaoundé I Yaoundé Cameroon Yaounde Central Hospital Yaoundé Cameroon Laquintiinie Hospital Douala Cameroon

Introduction :Congenital adrenal hyperplasia (CAH) is the most common cause of primary adrenal insufficiency. It is a rare monogenic recessive disorder. In African setting in absence of neonatal screening, the diagnosis is still late, based on a clinical approach. During this clinical enquiry, information from past history or pedigree of the patient is of a huge importance and may revealed surprises. Patients and Methods: In this observational study, we retrospectively included all patients with a diagnosis of CAH. The diagnosis of CAH was retained based on a high 17 hydroxyprogesterone level in addition to clinical and morphological findings. From patients’ files, we extracted data on family history of disease, pedigree, clinical findings and genetics when available of 39 patients from two endocrinopeadiatric centers. Results: In 13 (30%) families, we found 20 reported deaths of infant less than 12 months. In these 13 families, half of the patients followed had 21 hydroxylase deficiencies and had 11 hydroxylase deficiencies. Unsurprisingly, we suspected adrenal insufficiency in these patients at verbal autopsy even in families with a patient with 11 hydroxylase deficiency. Other non DSD malformations or genetic disorders with apparently no link with CAH were reported in 3 families. The father of a patient reported to have hypospadias. Conclusion: Each diagnosis of CAH made in our context is visible part of an iceberg. Behind a diagnosis of CAH made in our setting, is a long course of care, a dramatic past history revealing access to appropriate care disparity. Neonatal screening should thus be considered as an emergency.

关键词： Congenital Adrenal Hyperplasia

Acute Metabolic Complications of Diabetes in the Oueme-Plateau Provincial Teaching Hospital: Epidemiological, Clinical, Paraclinical and Evolutionary Aspects

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Open Journal of Internal Medicine 2024年第1期14卷 83-92页

作者： Finangnon Armand Wanvoegbe Comlan Jules Gninkoun Hubert Dedjan Kouessi Anthelme Agbodande Van Carrel Yongolo Prosper Singbo Elisé Boko Manchouhoud Alalade adele Cakpo Ingrid Thomas Angele Azon Kouanou Internal Medicine Department Oueme-Plateau Provincial Teaching Hospital Porto-Novo Benin Endocrinology Department Hubert Koutoukou Maga National Teaching Hospital Cotonou Benin Endocrinology Department Oueme-Plateau Provincial Teaching Hospital Porto-Novo Benin Internal Medicine Department Hubert Koutoukou Maga National Teaching Hospital Cotonou Benin

Introduction: Diabetes mellitus, a metabolic disease, is now an important public health problem across the world. Our aim was to study the epidemiological, clinical, paraclinical, and evolutionary aspects of acute metabolic complications (AMC) of diabetes in the endocrinology department of the Oueme-Plateau Provincial Teaching Hospital. Methods: This was a descriptive cross-sectional study with data collection based on the medical records of patients presenting with acute metabolic complications of diabetes in the endocrinology department of the Oueme-Plateau Provincial Teaching Hospital during the 3 years study period (from January 2020 to December 2022). Results: Over 788 patients hospitalized during the study period, 157 had an acute metabolic complication of diabetes, which is a hospital prevalence of 19.9%. Among these 157 cases, 140 were suitable for analysis and therefore constituted our study sample. The mean age of the patients was 49.9 ± 14.7 years, with 19 as minimum and 90 years as maximum. Most of them were women (52.4%). Hypertensive diabetics accounted for 54.9% of cases. Ketoacidosis was the most common complication (62.1%), followed by hyperosmolar hyperglycemic syndrome (23.6%) and hypoglycemia (14.3%). Infection (69.3%) and therapeutic noncompliance (22.9%) were the most common triggers. The average length period of their hospital stay was 7.1 ± 5.1 days, and the outcome was satisfactory in 87.9% of the cases. Unfortunately, there were 3.6% deaths during hospitalization. Conclusion: Acute metabolic complications of diabetes were dominated by ketoacidosis. Infection was the dominant factor in decompensation. Therapeutic education of diabetic patients as well as clinical and biological monitoring must be more stringent and rigorous.

关键词： Acute Metabolic Complications Diabetes Ketoacidosis Porto-Novo